HLA-G2, -G3, and -G4 isoforms expressed as nonmature cell surface glycoproteins inhibit NK and antigen-specific CTL cytolysis

Journal of Immunology

Volumn 166, Issue 8, 2001, Pages 5018-5026

  Riteau, B ^a   Rouas Freiss, N ^a   Menier, C ^a   Paul, P ^a   Dausset, J ^a   Carosella, E D ^a  

^a UNIVERSITÉ PARIS DIDEROT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HLA G ANTIGEN; HLA G1 ANTIGEN; HLA G2 ANTIGEN; HLA G3 ANTIGEN; HLA G4 ANTIGEN; HLA G5 ANTIGEN; HLA G6 ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; NATURAL KILLER CELL; PRIORITY JOURNAL;

EID: 0035871830     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.8.5018     Document Type: Article

References (51)

1. A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4
2. Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens
3. An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes
4. HLA-G revisited
5. The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association
6. Human placental HLA-G expression is restricted to differentiated cytotrophoblasts
7. A class I antigen, HLA-G, expressed in human trophoblasts
8. Non-classic sHLA class I in human oocyte culture medium
9. HLA-G expression during preimplantation human embryo development
10. The human amnion is a site of MHC class Ib expression: Evidence for the expression of HLA-E and HLA-G
11. Identification of a thymic epithelial cell subset sharing expression of the class lb HLA-G molecule with fetal trophoblasts
12. IL-10 selectively induces HLA-G expression in human trophoblasts and monocytes
13. Expression of HLA-G in human mononuclear phagocytes and selective induction by IFN-γ
14. Heterogeneity of HLA-G gene transcription and protein expression in malignant melanoma biopsies
15. Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis
16. The ILT2(LIR1) and CD94/NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells
17. Inhibitory receptors sensing HLA-G1 molecules in pregnancy: Decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-Gl-specific receptor
18. A human histocompatibility leucocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells
19. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules
20. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells
21. HLA-G-mediated inhibition of antigen-specific cytotoxic T lymphocytes
22. HLA-G inhibits the allogeneic proliferative response
23. Implication of HLA-G molecule in heart-graft acceptance
24. HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance
25. HLA-G, -E, -F preworkshop: Tools and protocols for analysis of non classical class I genes transcription and protein expression
26. The α1 domain of HLA-G1 and HLA-G2 inhibits cytotoxicity induced by natural killer cells: Is HLA-G the public ligand for natural killer cell inhibitory receptors?
27. HLA-G isoforms produced by placental cytotrophoblasts and found in amniotic fluid are due to unusual glycosylation
28. HLA-G: A tolerance molecule from the major histocompatibility complex
29. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
30. HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A
31. The immunotolerance role of HLA-G
32. NK cell receptor gene of the KIR family with two Ig domains but highest homology to KIR receptors with three Ig domains
33. The short forms of HLA-G are unlikely to play a role in pregnancy because they are not expressed at the cell surface
34. The full-length HLA-G1 and no other alternative form of HLA-G is expressed at the cell surface of transfected cells
35. Biochemical characterization of CD1d expression in the absence of β2-microglobulin
36. A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC which is not retained but is transported to the cell surface
37. The class I-b molecule Qa-1 forms heterodimers with H-2Ld and a novel 50-kD glycoprotein encoded centromeric to I-Eb
38. Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex
39. HLA-G polymorphisms and allele frequencies in Caucasians
40. The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18
41. Co-dominant expression of the HLA-G gene and various forms of alternatively spliced HLA-G mRNA in human first trimester trophoblast
42. Human cytomegalovirus gene products US3 and US6 down-regulate trophoblast class I molecules
43. Homozygous human TAP peptide transporter mutation in HLA class I deficiency
44. The role of peptide presentation in the physiological function of HLA-G
45. HLA-G1 protein expression is not essential for fetal survival
46. Homozygous HLA-G*0105N healthy individuals indicate thai membrane-anchored HLA-G1 molecule is not necessary for survival
47. Trophoblast cell line resistance to NK lysis mainly involves an HLA class I-independent mechanism
48. Early human decidual cells exhibit NK activity against the K562 cell line but not against first trimester trophoblast
49. Increased expression of human histocompatibility leucocyte antigen-G in colorectal cancer cells
50. Modulation of HLA-G antigens expression in myelomonocytic cells
51. The susceptibility to natural killer cell-mediated lysis of HLA class-I-positive melanomas reflects the expression of insufficient amounts of different HLA class I alleles