Association between two polymorphisms in the HLA-G gene and angiographic coronary artery disease

Molecular Medicine Reports

Volumn 5, Issue 5, 2012, Pages 1141-1145

  Boiocchi, Chiara ^a   Bozzini, Sara ^a   Zorzetto, Michele ^a   Pelissero, Gabriele ^b   Cuccia, Mariaclara ^a   Falcone, Colomba ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b IRCCS POLICLINICO SAN DONATO   (Italy)

Author keywords

Coronary artery disease; Human leukocyte antigen G; Immunogenetics; Polymorphisms

Indexed keywords

HLA G ANTIGEN;

ADULT; ANGIOGRAPHY; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENE; GENE DELETION; GENE EXPRESSION; GENE FREQUENCY; GENE INSERTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HLA G GENE; HOMOZYGOSITY; HUMAN; INDUSTRIALIZATION; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; POLYMERASE CHAIN REACTION; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR;

AGED; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; FEMALE; HAPLOTYPES; HLA-G ANTIGENS; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 84858212734     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.825     Document Type: Article

References (42)

1. Lusis AJ: Atherosclerosis. Nature 407: 233-234, 2000.
2. Ross R: Atherosclerosis is an inflammatory disease. Am Heart J 138: S419-S420, 1999.
3. Koenig W: Inflammation and coronary heart disease: an overview. Cardiol Rev 9: 31-35, 2001.
4. Heinrichs H and Orr HAT: HLA non-A,B,C class I genes: their structure and expression. Immunol Res 9: 265-274, 1990.
5. Redman CW, McMichael AJ, Stirrat GM, et al: Class I major histocompatibility complex antigens on human extravillous cytotrophoblast. Immunology 52: 457-468, 1984. (Pubitemid 14084347)
6. Crisa L, McMaster MT, Ishii JK, et al: Identification of a thymic epithelial cell subset sharing expression of the class Ib HLA-G molecule with fetal trophoblasts. J Exp Med 186: 289-298, 1997. (Pubitemid 27328029)
7. Le Discorde M, Moreau P, Sabatier P, et al: Expression of HLA-G in human cornea, an immuneprivileged tissue. Hum Immunol 64: 1039-1044, 2003. (Pubitemid 37413712)
8. Cirulli V, Zalatan J, McMaster M, et al: The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G. Diabetes 55: 1214-1222, 2006. (Pubitemid 44195357)
9. Hiby SE, King A, Sharkey A and Loke YW: Molecular studies of trophoblast HLA-G: polymorphism, isoforms, imprinting and expression in preimplantation embryo. Tissue Antigens 53: 1-13, 1999. (Pubitemid 29084169)
10. Wiendl H, Behrens L, Maier S, et al: Muscle fibers in inflammatory myopathies and cultured myoblasts express the nonclassical major histocompatibility antigen HLA-G. Ann Neurol 48: 679-684, 2000.
11. Aractingi S, Briand N, Le Danff C, et al: HLA-G and NK receptor are expressed in psoriatic skin: a possible pathway for regulating infiltrating T cells? Am J Pathol 159: 71-77, 2001. (Pubitemid 33704194)
12. Wiendl H, Feger U, Mittelbronn M, et al: Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity. Brain 128: 2689-2704, 2005. (Pubitemid 41552952)
13. Carosella ED, Paul P, Moreau P and Rouas-Freiss N: HLA-G and HLA-E: fundamental and pathophysiological aspects. Immunol Today 21: 532-534, 2000.
14. Carosella ED, Moreau P, Lemaoult J and Rouas-Freiss N: HLA-G: from biology to clinical benefits. Trends Immunol 29: 125-132, 2008.
15. Baricordi OR, Stignani M, Melchiorri L and Rizzo R: HLA-G and inflammatory diseases. Inflamm Allergy Drug Targets 7: 67-74, 2008.
16. Hofmeister V and Weiss EH: HLA-G modulates immune responses by diverse receptor interactions. Semin Cancer Biol 13: 317-323, 2003. (Pubitemid 38160930)
17. Bainbridge DR and Ellis SA: HLA-G suppresses proliferation of CD4 T-lymphocytes. J Reprod Immunol 48: 17-26, 2000.
18. + T cell regulatory mechanism. Proc Natl Acad Sci USA 98: 12150-12155, 2001.
19. Le Gal FA, Riteau B, Sedlik C, et al: HLA-G-mediated inhibition of antigen-specific cytotoxic T lymphocytes. Int Immunol 11: 1351-1356, 1999. (Pubitemid 29355674)
20. Bainbridge DR, Ellis SA and Sargent I: HLA-G suppresses proliferation of CD4(+) T-lymphocytes. J Reprod Immunol 48: 17-26, 2000.
21. Contini P, Ghio M, Merlo A, et al: Apoptosis of antigen-specific T lymphocytes upon the engagement of CD8 by soluble HLA class I molecules is Fas ligand/Fas mediated: evidence for the involvement of p56lck, calcium calmodulin kinase II, and Calcium-independent protein kinase C signaling pathways and for NF-kappaB and NF-AT nuclear translocation. J Immunol 175: 7244-7254, 2005. (Pubitemid 41713419)
22. Feger U, Tolosa E, Huang YH, et al: HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation. Blood 110: 568-577, 2007. (Pubitemid 47105395)
23. Harrison GA, Humphrey KE, Jakobsen IB and Cooper DW: A 14-bp deletion polymorphism in the HLA-G gene. Hum Mol Genet 2: 2200, 1993. (Pubitemid 24003437)
24. Van der Ven K, Skrablin S, Engels G and Krebs D: HLA-G polymorphisms and allele frequencies in Caucasians. Hum Immunol 59: 302-312, 1998. (Pubitemid 28225989)
25. Rousseau P, Le Discorde M, Mouillot G, et al: The 14 bp deletion-insertion polymorphism in the 3' UT region of the HLA-G gene influences HLA-G mRNA stability. Hum Immunol 64: 1005-1010, 2003. (Pubitemid 37413707)
26. Hviid TV, Hylenius S, Rørbye C and Nielsen LG: HLA-G allelic variants are associated with differences in the HLA-G mRNA isoform profile and HLA-G mRNA levels. Immunogenetics 55: 63-79, 2003. (Pubitemid 36702743)
27. Gazit E, Slomov Y, Goldberg I, et al: HLA-G is associated with Pemphigus vulgaris in Jewish patients. Hum Immunol 65: 39-46, 2004. (Pubitemid 38209933)
28. Glas J, Török HP, Tonenchi L, et al: The 14-bp deletion polymorphism in the HLA-G gene displays significant differences between ulcerative colitis and Crohn's disease and is associated with leocecal resection in Crohn's disease. Int Immunol 19: 621-626, 2007. (Pubitemid 47072205)
29. Veit TD, Vianna P, Scheibel I, et al: Association of the HLA-G 14-bp insertion/deletion polymorphism with juvenile idiopathic arthritis and rheumatoid arthritis. Tissue Antigens 71: 440-444, 2009.
30. Hviid TV, Hylenius S, Hoegh AM, et al: HLA-G polymorphisms in couples with recurrent spontaneous abortions. Tissue Antigens 60: 122-132, 2002. (Pubitemid 35305618)
31. Rebmann V, van der Ven K, Passler M, et al: Association of soluble HLA-G plasma levels with HLA-G alleles. Tissue Antigens 57: 15-21, 2001. (Pubitemid 32151071)
32. Farragher TM, Goodson NJ, Naseem H, et al: Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis. Arthritis Rheum 58: 359-369, 2008. (Pubitemid 351294870)
33. Torres MI, Le Discorde M, Lorite P, et al: Expression of HLA-G in inflammatory bowel disease provides a potential way to distinguish between ulcerative colitis and Crohn's disease. Int Immunol 16: 579-583, 2004. (Pubitemid 38489432)
34. Downs-Kelly E, Schade AE and Hansel DE: The role of HLA-G in gastrointestinal inflammatory disease and malignancy. Semin Cancer Biol 17: 451-458, 2007. (Pubitemid 350064560)
35. Nicolae D, Cox NJ, Lester LA, et al: Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet 76: 349-357, 2005. (Pubitemid 40129561)
36. Rizzo R, Mapp CE, Melchiorri L, et al: Defective production of soluble HLA-G molecules by peripheral blood monocytes in patients with asthma. J Allergy Clin Immunol 115: 508-513, 2005. (Pubitemid 40341703)
37. Maier S, Geraghty DE and Weiss EH: Expression and regulation of HLA-G in human glioma cell lines. Transplant Proc 31: 1849-1853, 1999. (Pubitemid 29275481)
38. Wiendl H: HLA-G in the nervous system. Hum Immunol 68: 286-293, 2007.
39. Fainardi E, Rizzo R, Melchiorri L, et al: Presence of detectable levels of soluble HLA-G molecules in CSF of relapsing-remitting multiple sclerosis: relationship with CSF soluble HLA-I and IL-10 concentrations and MRI findings. J Neuroimmunol 142: 149-158, 2003. (Pubitemid 38368598)
40. Dorling A, Monk N and Lechler R: HLA-G inhibits the transendothelial migration of human NK cells. Eur J Immunol 30: 586-593, 2000. (Pubitemid 30098852)
41. Forte P, Pazmany L, Matter-Reissmann UB, et al: HLA-G inhibits rolling adhesion of activated human NK cells on porcine endothelial cells. J Immunol 167: 6002-6008, 2001. (Pubitemid 33062798)
42. Le Bouteiller P, Pizzato N, Barakonyi A and Solier C: HLA-G, pre-eclampsia, immunity and vascular events. J Reprod Immunol 59: 219-234, 2003. (Pubitemid 36945237)