-
1
-
-
0034144269
-
A new classification system and their role in immunity
-
Zlotnik A, Yoshie O. Chemokines: A new classification system and their role in immunity. Immunity. 2000; 12:121-127.
-
(2000)
Immunity
, vol.12
, pp. 121-127
-
-
Zlotnik, A.1
Chemokines, Y.O.2
-
2
-
-
0030842854
-
The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4
-
D'Apuzzo M, Rolink A, Loetscher M, Hoxie JA, Clark-Lewis I, Melchers F, Baggiolini M, Moser B. The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4. Eur J Immunol. 1997; 27:1788-1793.
-
(1997)
Eur J Immunol
, vol.27
, pp. 1788-1793
-
-
D'Apuzzo, M.1
Rolink, A.2
Loetscher, M.3
Hoxie, J.A.4
Clark-Lewis, I.5
Melchers, F.6
Baggiolini, M.7
Moser, B.8
-
3
-
-
0033057179
-
Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors
-
Aiuti A, Tavian M, Cipponi A, Ficara F, Zappone E, Hoxie J, Peault B, Bordignon C. Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors. Eur J Immunol. 1999; 29:1823-1831.
-
(1999)
Eur J Immunol
, vol.29
, pp. 1823-1831
-
-
Aiuti, A.1
Tavian, M.2
Cipponi, A.3
Ficara, F.4
Zappone, E.5
Hoxie, J.6
Peault, B.7
Bordignon, C.8
-
4
-
-
0035383788
-
Janus kinase 2 is involved in stromal cell-derived factor-1α-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells
-
Zhang XF, Wang JF, Matczak E, Proper JA, Groopman JE. Janus kinase 2 is involved in stromal cell-derived factor-1α-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. Blood. 2001; 97:3342-3348.
-
(2001)
Blood
, vol.97
, pp. 3342-3348
-
-
Zhang, X.F.1
Wang, J.F.2
Matczak, E.3
Proper, J.A.4
Groopman, J.E.5
-
5
-
-
57349105727
-
Comparison of the potential multiple binding modes of bicyclam, monocylam, and noncyclam smallmolecule CXC chemokine receptor 4 inhibitors
-
Wong RS, Bodart V, Metz M, Labrecque J, Bridger G, Fricker SP. Comparison of the potential multiple binding modes of bicyclam, monocylam, and noncyclam smallmolecule CXC chemokine receptor 4 inhibitors. Mol Pharmacol. 2008; 74:1485-1495.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 1485-1495
-
-
Wong, R.S.1
Bodart, V.2
Metz, M.3
Labrecque, J.4
Bridger, G.5
Fricker, S.P.6
-
6
-
-
33745614886
-
Structural analogues of AMD3100 mobilise haematopoietic progenitor cells from bone marrow in vivo according to their ability to inhibit CXCL12 binding to CXCR4 in vitro
-
Martin C, Bridger GJ, Rankin SM. Structural analogues of AMD3100 mobilise haematopoietic progenitor cells from bone marrow in vivo according to their ability to inhibit CXCL12 binding to CXCR4 in vitro. Br J Haematol. 2006; 134:326-329.
-
(2006)
Br J Haematol
, vol.134
, pp. 326-329
-
-
Martin, C.1
Bridger, G.J.2
Rankin, S.M.3
-
7
-
-
64249173226
-
The AMD3100 story: The path to the discovery of a stem cell mobilizer (Mozobil)
-
De Clercq E. The AMD3100 story: The path to the discovery of a stem cell mobilizer (Mozobil). Biochem Pharmacol. 2009; 77:1655-1664.
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 1655-1664
-
-
De Clercq, E.1
-
8
-
-
33746685587
-
Characterization of the molecular pharmacology of AMD3100: A specific antagonist of the G-protein coupled chemokine receptor, CXCR4
-
Fricker SP, Anastassov V, Cox J, Darkes MC, Grujic O, Idzan SR, Labrecque J, Lau G, Mosi RM, Nelson KL, Qin L, Santucci Z, Wong RS. Characterization of the molecular pharmacology of AMD3100: A specific antagonist of the G-protein coupled chemokine receptor, CXCR4. Biochem Pharmacol. 2006; 72:588-596.
-
(2006)
Biochem Pharmacol.
, vol.72
, pp. 588-596
-
-
Fricker, S.P.1
Anastassov, V.2
Cox, J.3
Darkes, M.C.4
Grujic, O.5
Idzan, S.R.6
Labrecque, J.7
Lau, G.8
Mosi, R.M.9
Nelson, K.L.10
Qin, L.11
Santucci, Z.12
Wong, R.S.13
-
9
-
-
79251599039
-
Blockade of CXCR4 in oral squamous cell carcinoma inhibits lymph node metastases
-
Uchida D, Onoue T, Kuribayashi N, Tomizuka Y, Tamatani T, Nagai H, Miyamoto Y. Blockade of CXCR4 in oral squamous cell carcinoma inhibits lymph node metastases. Eur J Cancer. 2011; 47:452-459.
-
(2011)
Eur J Cancer
, vol.47
, pp. 452-459
-
-
Uchida, D.1
Onoue, T.2
Kuribayashi, N.3
Tomizuka, Y.4
Tamatani, T.5
Nagai, H.6
Miyamoto, Y.7
-
10
-
-
78650194206
-
CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: A novel target for therapy
-
Singh S, Srivastava SK, Bhardwaj A, Owen LB, Singh AP. CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: A novel target for therapy. Br J Cancer. 2010; 103:1671-1679.
-
(2010)
Br J Cancer
, vol.103
, pp. 1671-1679
-
-
Singh, S.1
Srivastava, S.K.2
Bhardwaj, A.3
Owen, L.B.4
Singh, A.P.5
-
11
-
-
0034120373
-
Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers
-
Hendrix CW, Flexner C, MacFarland RT, Giandomenico C, Fuchs EJ, Redpath E, Bridger G, Henson GW. Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers. Antimicrob Agents Chemother. 2000; 44:1667-1673.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1667-1673
-
-
Hendrix, C.W.1
Flexner, C.2
MacFarland, R.T.3
Giandomenico, C.4
Fuchs, E.J.5
Redpath, E.6
Bridger, G.7
Henson, G.W.8
-
12
-
-
2442643981
-
Stroma cell-derived factor 1α mediates desensitization of human neutrophil respiratory burst in synovial fluid from rheumatoid arthritic patients
-
Lenoir M, Djerdjouri B, Perianin A. Stroma cell-derived factor 1α mediates desensitization of human neutrophil respiratory burst in synovial fluid from rheumatoid arthritic patients. J Immunol. 2004; 172:7136-7143.
-
(2004)
J Immunol
, vol.172
, pp. 7136-7143
-
-
Lenoir, M.1
Djerdjouri, B.2
Perianin, A.3
-
13
-
-
0036116174
-
AMD3100, a CXCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity
-
Lukacs NW, Berlin A, Schols D, Skerlj RT, Bridger GJ. AMD3100, a CXCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity. Am J Pathol. 2002; 160:1353-1360.
-
(2002)
Am J Pathol
, vol.160
, pp. 1353-1360
-
-
Lukacs, N.W.1
Berlin, A.2
Schols, D.3
Skerlj, R.T.4
Bridger, G.J.5
-
14
-
-
38349073636
-
Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway
-
Otsuru S, Tamai K, Yamazaki T, Yoshikawa H, Kaneda Y. Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway. Stem Cells. 2008; 26:223-234.
-
(2008)
Stem Cells
, vol.26
, pp. 223-234
-
-
Otsuru, S.1
Tamai, K.2
Yamazaki, T.3
Yoshikawa, H.4
Kaneda, Y.5
-
15
-
-
34547114271
-
A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells
-
Zhu W, Boachie-Adjei O, Rawlins BA, Frenkel B, Boskey AL, Ivashkiv LB, Blobel CP. A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells. J Biol Chem. 2007; 282:18676-18685.
-
(2007)
J Biol Chem
, vol.282
, pp. 18676-18685
-
-
Zhu, W.1
Boachie-Adjei, O.2
Rawlins, B.A.3
Frenkel, B.4
Boskey, A.L.5
Ivashkiv, L.B.6
Blobel, C.P.7
-
16
-
-
77953536520
-
Stromal derived factor-1 regulates bone morphogenetic protein 2-induced osteogenic differentiation of primary mesenchymal stem cells
-
Hosogane N, Huang Z, Rawlins BA, Liu X, Boachie-Adjei O, Boskey AL, Zhu W. Stromal derived factor-1 regulates bone morphogenetic protein 2-induced osteogenic differentiation of primary mesenchymal stem cells. Int J Biochem Cell Biol. 2010; 42:1132-1141.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 1132-1141
-
-
Hosogane, N.1
Huang, Z.2
Rawlins, B.A.3
Liu, X.4
Boachie-Adjei, O.5
Boskey, A.L.6
Zhu, W.7
-
17
-
-
61649090805
-
Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model
-
Kitaori T, Ito H, Schwarz EM, Tsutsumi R, Yoshitomi H, Oishi S, Nakano M, Fujii N, Nagasawa T, Nakamura T. Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model. Arthritis Rheum. 2009; 60:813-823.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 813-823
-
-
Kitaori, T.1
Ito, H.2
Schwarz, E.M.3
Tsutsumi, R.4
Yoshitomi, H.5
Oishi, S.6
Nakano, M.7
Fujii, N.8
Nagasawa, T.9
Nakamura, T.10
-
18
-
-
0032983542
-
Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential
-
Wang D, Christensen K, Chawla K, Xiao G, Krebsbach PH, Franceschi RT. Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res. 1999; 14:893-903.
-
(1999)
J Bone Miner Res
, vol.14
, pp. 893-903
-
-
Wang, D.1
Christensen, K.2
Chawla, K.3
Xiao, G.4
Krebsbach, P.H.5
Franceschi, R.T.6
-
19
-
-
77957961918
-
Bone morphogenetic protein receptor in the osteogenic differentiation of rat bone marrow stromal cells
-
Wang A, Ding X, Sheng S, Yao Z. Bone morphogenetic protein receptor in the osteogenic differentiation of rat bone marrow stromal cells. Yonsei Med J. 2010; 51:740-745.
-
(2010)
Yonsei Med J
, vol.51
, pp. 740-745
-
-
Wang, A.1
Ding, X.2
Sheng, S.3
Yao, Z.4
-
20
-
-
80051945259
-
Myocyte enhancer factor 2c, an osteoblast transcription factor identified by dimethyl sulfoxide (DMSO)-enhanced mineralization
-
Stephens AS, Stephens SR, Hobbs C, Hutmacher DW, Bacic-Welsh D, Woodruff MA, Morrison NA. Myocyte enhancer factor 2c, an osteoblast transcription factor identified by dimethyl sulfoxide (DMSO)-enhanced mineralization. J Biol Chem. 2011; 286:30071-30086.
-
(2011)
J Biol Chem
, vol.286
, pp. 30071-30086
-
-
Stephens, A.S.1
Stephens, S.R.2
Hobbs, C.3
Hutmacher, D.W.4
Bacic-Welsh, D.5
Woodruff, M.A.6
Morrison, N.A.7
-
21
-
-
58649107153
-
Matrix vesicles originate from apical membrane microvilli of mineralizing osteoblast-like Saos-2 cells
-
Thouverey C, Strzelecka-Kiliszek A, Balcerzak M, Buchet R, Pikula S. Matrix vesicles originate from apical membrane microvilli of mineralizing osteoblast-like Saos-2 cells. J Cell Biochem. 2009; 106:127-138.
-
(2009)
J Cell Biochem
, vol.106
, pp. 127-138
-
-
Thouverey, C.1
Strzelecka-Kiliszek, A.2
Balcerzak, M.3
Buchet, R.4
Pikula, S.5
-
22
-
-
66149153412
-
Mechanical force induces type I collagen expression in human periodontal ligament fibroblasts through activation of ERK/JNK and AP-1
-
Kook SH, Hwang JM, Park JS, Kim EM, Heo JS, Jeon YM, Lee JC. Mechanical force induces type I collagen expression in human periodontal ligament fibroblasts through activation of ERK/JNK and AP-1. J Cell Biochem. 2009; 106:1060-1067.
-
(2009)
J Cell Biochem
, vol.106
, pp. 1060-1067
-
-
Kook, S.H.1
Hwang, J.M.2
Park, J.S.3
Kim, E.M.4
Heo, J.S.5
Jeon, Y.M.6
Lee, J.C.7
-
23
-
-
0347397553
-
Stromal cellderived factor-1 (SDF-1) recruits osteoclast precursors by inducing chemotaxis, matrix metalloproteinase-9 (MMP-9) activity, and collagen transmigration
-
Yu X, Huang Y, Collin-Osdoby P, Osdoby P. Stromal cellderived factor-1 (SDF-1) recruits osteoclast precursors by inducing chemotaxis, matrix metalloproteinase-9 (MMP-9) activity, and collagen transmigration. J Bone Miner Res. 2003; 18:1404-1418.
-
(2003)
J Bone Miner Res
, vol.18
, pp. 1404-1418
-
-
Yu, X.1
Huang, Y.2
Collin-Osdoby, P.3
Osdoby, P.4
-
24
-
-
18544379954
-
Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells
-
Kortesidis A, Zannettino A, Isenmann S, Shi S, Lapidot T, Gronthos S. Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells. Blood. 2005; 105:3793-3801.
-
(2005)
Blood
, vol.105
, pp. 3793-3801
-
-
Kortesidis, A.1
Zannettino, A.2
Isenmann, S.3
Shi, S.4
Lapidot, T.5
Gronthos, S.6
-
25
-
-
79960663308
-
Conditional inactivation of the CXCR4 receptor in osteoprecursors reduces postnatal bone formation due to impaired osteoblast development
-
Zhu W, Liang G, Huang Z, Doty SB, Boskey AL. Conditional inactivation of the CXCR4 receptor in osteoprecursors reduces postnatal bone formation due to impaired osteoblast development. J Biol Chem. 2011; 286:26794-26805.
-
(2011)
J Biol Chem
, vol.286
, pp. 26794-26805
-
-
Zhu, W.1
Liang, G.2
Huang, Z.3
Doty, S.B.4
Boskey, A.L.5
-
26
-
-
84862777340
-
Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect
-
Kumar S, Ponnazhagan S. Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect. Bone. 2012; 50:1012-1018.
-
(2012)
Bone
, vol.50
, pp. 1012-1018
-
-
Kumar, S.1
Ponnazhagan, S.2
-
27
-
-
0030666372
-
Cbfa1 a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GW, Beddington RS, Mundlos S, Olsen BR, Selby PB, Owen MJ. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell. 1997; 89:765-771.
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
Rosewell, I.R.6
Stamp, G.W.7
Beddington, R.S.8
Mundlos, S.9
Olsen, B.R.10
Selby, P.B.11
Owen, M.J.12
-
28
-
-
80053261320
-
SDF-1/CXCR4 mediates acute protection of cardiac function through myocardial STAT3 signaling following global ischemia/reperfusion injury
-
Huang C, Gu H, Zhang W, Manukyan MC, Shou W, Wang M. SDF-1/CXCR4 mediates acute protection of cardiac function through myocardial STAT3 signaling following global ischemia/reperfusion injury. Am J Physiol Heart Circ Physiol. 2011; 301:H1496-1505.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Huang, C.1
Gu, H.2
Zhang, W.3
Manukyan, M.C.4
Shou, W.5
Wang, M.6
-
29
-
-
0031966146
-
Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblastic cells
-
Nishimura R, Moriyama K, Yasukawa K, Mundy GR, Yoneda T. Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblastic cells. J Bone Miner Res. 1998; 13:777-785.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 777-785
-
-
Nishimura, R.1
Moriyama, K.2
Yasukawa, K.3
Mundy, G.R.4
Yoneda, T.5
-
30
-
-
33746599062
-
A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation
-
Itoh S, Udagawa N, Takahashi N, Yoshitake F, Narita H, Ebisu S, Ishihara K. A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation. Bone. 2006; 39:505-512.
-
(2006)
Bone
, vol.39
, pp. 505-512
-
-
Itoh, S.1
Udagawa, N.2
Takahashi, N.3
Yoshitake, F.4
Narita, H.5
Ebisu, S.6
Ishihara, K.7
-
31
-
-
75749101014
-
Bone morphogenetic protein 2 and dexamethasone synergistically increase alkaline phosphatase levels through JAK/STAT signaling in C3H10T1/2 cells
-
Mikami Y, Asano M, Honda MJ, Takagi M. Bone morphogenetic protein 2 and dexamethasone synergistically increase alkaline phosphatase levels through JAK/STAT signaling in C3H10T1/2 cells. J Cell Physiol. 2010; 223:123-133.
-
(2010)
J Cell Physiol
, vol.223
, pp. 123-133
-
-
Mikami, Y.1
Asano, M.2
Honda, M.J.3
Takagi, M.4
-
32
-
-
77957275514
-
Highly efficient osteogenic differentiation of human mesenchymal stem cells by eradication of STAT3 signaling
-
Levy O, Ruvinov E, Reem T, Granot Y, Cohen S. Highly efficient osteogenic differentiation of human mesenchymal stem cells by eradication of STAT3 signaling. Int J Biochem Cell Biol. 2010; 42:1823-1830.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 1823-1830
-
-
Levy, O.1
Ruvinov, E.2
Reem, T.3
Granot, Y.4
Cohen, S.5
-
33
-
-
43449139993
-
Physical and functional interactions between STAT5 and Runx transcription factors
-
Ogawa S, Satake M, Ikuta K. Physical and functional interactions between STAT5 and Runx transcription factors. J Biochem. 2008; 143:695-709.
-
(2008)
J Biochem
, vol.143
, pp. 695-709
-
-
Ogawa, S.1
Satake, M.2
Ikuta, K.3
-
34
-
-
35649019828
-
Mechanistic roles of leptin in osteogenic stimulation in thoracic ligament flavum cells
-
Fan D, Chen Z, Chen Y, Shang Y. Mechanistic roles of leptin in osteogenic stimulation in thoracic ligament flavum cells. J Biol Chem. 2007; 282:29958-29966.
-
(2007)
J Biol Chem
, vol.282
, pp. 29958-29966
-
-
Fan, D.1
Chen, Z.2
Chen, Y.3
Shang, Y.4
-
35
-
-
16244393552
-
Growth hormone attenuates the transcriptional activity of Runx2 by facilitating its physical association with Stat3β
-
Ziros PG, Georgakopoulos T, Habeos I, Basdra EK, Papavassiliou AG. Growth hormone attenuates the transcriptional activity of Runx2 by facilitating its physical association with Stat3β. J Bone Miner Res. 2004; 19:1892-1904
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1892-1904
-
-
Ziros, P.G.1
Georgakopoulos, T.2
Habeos, I.3
Basdra, E.K.4
Papavassiliou, A.G.5
|