In vitro release and in vitro-in vivo correlation for silybin meglumine incorporated into Hollow-type mesoporous silica nanoparticles

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 753-762

  Cao, Xia ^a   Deng, Wen Wen ^a   Fu, Min ^a   Wang, Liang ^a   Tong, Shan Shan ^a   Wei, Ya Wei ^a   Xu, Ying ^a   Su, Wei Yan ^a   Xu, Xi Ming ^a   Yu, Jiang Nan ^a  

^a JIANGSU UNIVERSITY   (China)

Author keywords

Hollow type mesoporous silica nanoparticle; In vitro dissolution; In vitro in vivo correlation; In vivo absorption; Silybin meglumine

Indexed keywords

NANOPARTICLE; SILIBININ; DRUG CARRIER; MEGLUMINE; SILICON DIOXIDE; SILYMARIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOG; DRUG ABSORPTION; DRUG SOLUBILITY; GASTROINTESTINAL SECRETION; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PARTICLE SIZE; PROCESS DEVELOPMENT; STOMACH JUICE; SUSTAINED DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY; ABSORPTION; ANALYSIS OF VARIANCE; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; METABOLISM; PH; POROSITY; STATISTICAL MODEL;

ABSORPTION; ANALYSIS OF VARIANCE; ANIMALS; DOGS; DRUG CARRIERS; GASTRIC JUICE; HYDROGEN-ION CONCENTRATION; LINEAR MODELS; MALE; MEGLUMINE; MODELS, BIOLOGICAL; NANOPARTICLES; PARTICLE SIZE; POROSITY; SILICON DIOXIDE; SILYMARIN;

EID: 84862316155     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S28348     Document Type: Article

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