A pH-sensitive multifunctional gene carrier assembled via layer-by-layer technique for efficient gene delivery

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 925-939

  Li, Peng ^a   Liu, Donghua ^a   Miao, Lei ^a   Liu, Chunxi ^a   Sun, Xiaoli ^a   Liu, Yongjun ^a   Zhang, Na ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Gene delivery; Layer by layer; Multifunctional nanovector; pH sensitivity

Indexed keywords

CHITOSAN; DNA PROTAMINE DNA COMPLEX; DRUG CARRIER; LIPOSOME; MACROGOL; NUCLEASE; O CARBOXYMETHYL CHITOSAN; UNCLASSIFIED DRUG; CARBOXYMETHYL CHITOSAN; CARBOXYMETHYL-CHITOSAN; CATION; DNA; DRUG DERIVATIVE; GREEN FLUORESCENT PROTEIN; PROTAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL TRANSPORT; CELL VIABILITY; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION KINETICS; DRUG EFFICACY; DRUG MECHANISM; ENZYME DEGRADATION; FLUORESCENCE ANALYSIS; GENE DELIVERY SYSTEM; GENE VECTOR; GENETIC TRANSFECTION; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PH MEASUREMENT; PHYSICAL CHEMISTRY; PROCESS OPTIMIZATION; SENSITIVITY ANALYSIS; TUMOR XENOGRAFT; ANIMAL; BIOLOGICAL MODEL; BLOOD; CELL STRAIN HEPG2; CHEMISTRY; DRUG STABILITY; FLUORESCENCE MICROSCOPY; GENETICS; HUMAN; METABOLISM; METHODOLOGY; PARTICLE SIZE; PH;

MUS;

ANIMALS; CATIONS; CHITOSAN; DNA; DRUG STABILITY; GREEN FLUORESCENT PROTEINS; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MICE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; PARTICLE SIZE; PROTAMINES; TRANSFECTION;

EID: 84862306302     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S26955     Document Type: Article

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