NAD + levels control Ca 2+ store replenishment and mitogen-induced increase of cytosolic Ca 2+by cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes

Journal of Biological Chemistry

Volumn 287, Issue 25, 2012, Pages 21067-21081

  Magnone, Mirko ^a   Bauer, Inga ^b   Poggi, Alessandro ^c   Mannino, Elena ^a   Sturla, Laura ^a   Brini, Marisa ^e   Zocchi, Elena ^a,d   De Flora, Antonio ^a   Nencioni, Alessio ^b   Bruzzone, Santina ^a,d  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d ADVANCED BIOTECHNOLOGY CENTER   (Italy)

^e UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHANNEL GATING; CYTOKINE SECRETIONS; CYTOSOLIC; ENDOPLASMIC RETICULUM; HUMAN T LYMPHOCYTES; INTRACELLULAR CA; JURKAT CELL; MITOGENS; NICOTINAMIDE MONONUCLEOTIDE; NICOTINIC ACID; PERIPHERAL BLOOD LYMPHOCYTES; PHOSPHORIBOSYLTRANSFERASE; SECOND MESSENGER; T CELL ACTIVATION; T CELLS; T LYMPHOCYTES;

AMIDES; CELL MEMBRANES; CYTOLOGY; PHYSIOLOGY;

CALCIUM;

CALCIUM ION; CD38 ANTIGEN; INTERLEUKIN 2; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NICOTINIC ACID; SMALL INTERFERING RNA; THAPSIGARGIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CELL ASSAY; CELLULAR DISTRIBUTION; CHANNEL GATING; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOCYTE PROLIFERATION; NUCLEIC ACID ANALYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SENSITIVITY ANALYSIS; T LYMPHOCYTE ACTIVATION; UPREGULATION;

ACRYLAMIDES; CALCIUM; CALCIUM SIGNALING; CELL PROLIFERATION; CYCLIC ADP-RIBOSE; CYTOKINES; ENZYME INHIBITORS; HUMANS; INTERLEUKIN-2; ION CHANNEL GATING; JURKAT CELLS; MITOGENS; NAD; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PIPERIDINES; T-LYMPHOCYTES; THAPSIGARGIN; TRPM CATION CHANNELS;

EID: 84862285448     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.324269     Document Type: Article

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