Activation of Wnt11 by transforming growth factor-β drives mesenchymal gene expression through non-canonical Wnt protein signaling in renal epithelial cells

Journal of Biological Chemistry

Volumn 287, Issue 25, 2012, Pages 21290-21302

  Zhang, Peng ^a   Cai, Yi ^a   Soofi, Abdul ^a   Dressler, Gregory R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C-JUN N-TERMINAL KINASE; CANONICAL WNT SIGNALING; COOPERATIVITY; EPITHELIAL CELLS; IN-VITRO; IN-VIVO; MARKER GENES; PROTEIN SIGNALING; RENAL EPITHELIAL CELLS; RENAL FIBROSIS; RENAL INTERSTITIAL FIBROSIS; RENAL TISSUE; SIGNALING PATHWAYS; TRANSFORMING GROWTH FACTORS; WNT SIGNALING PATHWAYS;

CELLS; PHOSPHORYLATION; PIGMENTS; SIGNALING;

GENE EXPRESSION;

MESSENGER RNA; SMAD2 PROTEIN; SMAD3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; WNT11 PROTEIN;

ALPHA SMA GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; CALCIUM SIGNALING; CELL IMMORTALIZATION; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC SCREENING; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; KIDNEY FIBROSIS; MARKER GENE; MESENCHYME CELL; MOLECULAR MODEL; MOUSE; NONHUMAN; PAI1 GENE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SNAIL1 GENE; TRANSIENT EXPRESSION; TRANSIENT TRANSFECTION; UPREGULATION; URETER OBSTRUCTION; WESTERN BLOTTING; WNT SIGNALING PATHWAY; WNT11 GENE; ZEB1 GENE;

ANIMALS; ANTIGENS, DIFFERENTIATION; CELL LINE; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FIBROSIS; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; KIDNEY; KIDNEY DISEASES; MAP KINASE KINASE 4; MICE; TRANSFORMING GROWTH FACTOR BETA1; URETERAL OBSTRUCTION; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84862279514     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.357202     Document Type: Article

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