Structure-activity relationship and mode of action of N-(6-ferrocenyl-2- naphthoyl) dipeptide ethyl esters: Novel organometallic anticancer compounds

Journal of Medicinal Chemistry

Volumn 55, Issue 11, 2012, Pages 5455-5466

  Mooney, Áine ^a   Tiedt, Rachel ^a   Maghoub, Thamir ^a   O'Donovan, Norma ^a   Crown, John ^a,b   White, Blánaid ^a   Kenny, Peter T M ^a  

^a DUBLIN CITY UNIVERSITY   (Ireland)

^b ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; N (6 FERROCENYL 2 NAPHTHOYL) BETA ALANINE GLYCINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) DIPEPTIDE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) GAMMA AMINOBUTYRIC ACID GLYCINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) GLYCINE BETA ALANINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) GLYCINE D ALANINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) GLYCINE GAMMA AMINOBUTYRIC ACID ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) GLYCINE GLYCINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) GLYCINE L LEUCINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) GLYCINE L PHENYLALANINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) GLYCINE SARCOSINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) L ALANINE GLYCINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) L ALANINE L ALANINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) L ALANINE L LEUCINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) L ALANINE L PHENYLALANINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) SARCOSINE GLYCINE ETHYL ESTER; N (6 FERROCENYL 2 NAPHTHOYL) SARCOSINE SARCOSINE ETHYL ESTER; ORGANOMETALLIC COMPOUND; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MELANOMA CELL; OXIDATION; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; COORDINATION COMPLEXES; DIPEPTIDES; DNA DAMAGE; DRUG SCREENING ASSAYS, ANTITUMOR; ESTERS; FERROUS COMPOUNDS; GUANINE; HUMANS; NAPHTHALENES; OXIDATION-REDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84862275462     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3004027     Document Type: Article

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