-
1
-
-
0032478615
-
Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid
-
An, S., T. Bleu, O. G. Hallmark, and E. J. Goetzl. 1998. Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid. J. Biol. Chem. 273:7906-7910.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7906-7910
-
-
An, S.1
Bleu, T.2
Hallmark, O.G.3
Goetzl, E.J.4
-
3
-
-
0034726004
-
Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species: Structure-activity relationship of cloned LPA receptors
-
Bandoh, K., J. Aoki, A. Taira, M. Tsujimoto, H. Arai, and K. Inoue. 2000. Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species: structure-activity relationship of cloned LPA receptors. FEBS Lett. 478:159-165.
-
(2000)
FEBS Lett.
, vol.478
, pp. 159-165
-
-
Bandoh, K.1
Aoki, J.2
Taira, A.3
Tsujimoto, M.4
Arai, H.5
Inoue, K.6
-
4
-
-
0033600761
-
Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid
-
Bandoh, K., J. Aoki, H. Hosono, S. Kobayashi, T. Kobayashi, K. Murakami-Murofushi, M. Tsujimoto, H. Arai, and K. Inoue. 1999. Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid. J. Biol. Chem. 274:27776-27785.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27776-27785
-
-
Bandoh, K.1
Aoki, J.2
Hosono, H.3
Kobayashi, S.4
Kobayashi, T.5
Murakami-Murofushi, K.6
Tsujimoto, M.7
Arai, H.8
Inoue, K.9
-
5
-
-
0032032681
-
Expression of catalytically inactive phospholipase C-β disrupts phospholipase C-β and mitogen-activated protein kinase signaling and inhibits small cell lung cancer growth
-
Beekman, A., B. Helfrich, P. A. Bunn, Jr., and L. E. Heasley. 1998. Expression of catalytically inactive phospholipase C-β disrupts phospholipase C-β and mitogen-activated protein kinase signaling and inhibits small cell lung cancer growth. Cancer Res. 58:910-913.
-
(1998)
Cancer Res.
, vol.58
, pp. 910-913
-
-
Beekman, A.1
Helfrich, B.2
Bunn Jr., P.A.3
Heasley, L.E.4
-
6
-
-
0034524664
-
ERM-Merlin and EBP50 protein families in plasma membrane organization and function
-
Bretscher, A., D. Chambers, R. Nguyen, and D. Reczek. 2000. ERM-Merlin and EBP50 protein families in plasma membrane organization and function. Annu. Rev. Cell Dev. Biol. 16:113-143.
-
(2000)
Annu. Rev. Cell Dev. Biol.
, vol.16
, pp. 113-143
-
-
Bretscher, A.1
Chambers, D.2
Nguyen, R.3
Reczek, D.4
-
7
-
-
0036404954
-
+ exchanger regulatory factor 2 mediates phosphorylation of serum- and glucocorticoid-induced protein kinase 1 by 3-phosphoinositide-dependent protein kinase 1
-
+ exchanger regulatory factor 2 mediates phosphorylation of serum- and glucocorticoid-induced protein kinase 1 by 3-phosphoinositide-dependent protein kinase 1. Biochem. Biophys. Res. Commun. 298:207-215.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.298
, pp. 207-215
-
-
Chun, J.1
Kwon, T.2
Lee, E.3
Suh, P.G.4
Choi, E.J.5
Kang, S.S.6
-
8
-
-
0036786445
-
Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to lpa(2)
-
Contos, J. J., I. Ishii, N. Fukushima, M. A. Kingsbury, X. Ye, S. Kawamura, J. H. Brown, and J. Chun. 2002. Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Mol. Cell. Biol. 22:6921-6929.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6921-6929
-
-
Contos, J.J.1
Ishii, I.2
Fukushima, N.3
Kingsbury, M.A.4
Ye, X.5
Kawamura, S.6
Brown, J.H.7
Chun, J.8
-
9
-
-
0034162958
-
Genomic characterization of the lysophosphatidic acid receptor gene, lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA
-
Contos, J. J., and J. Chun. 2000. Genomic characterization of the lysophosphatidic acid receptor gene, lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA. Genomics 64:155-169.
-
(2000)
Genomics
, vol.64
, pp. 155-169
-
-
Contos, J.J.1
Chun, J.2
-
11
-
-
0035021984
-
Lysophosphatidic acid and ovarian cancer: A paradigm for tumorigenesis and patient management
-
Erickson, J. R., Y. Hasegawa, X. Fang, A. Eder, M. Mao, T. Furui, J. Aoki, A. Morris, and G. B. Mills. 2001. Lysophosphatidic acid and ovarian cancer: a paradigm for tumorigenesis and patient management. Prostaglandins 64: 63-81.
-
(2001)
Prostaglandins
, vol.64
, pp. 63-81
-
-
Erickson, J.R.1
Hasegawa, Y.2
Fang, X.3
Eder, A.4
Mao, M.5
Furui, T.6
Aoki, J.7
Morris, A.8
Mills, G.B.9
-
12
-
-
0036120653
-
Convergence of multiple signaling cascades at glycogen synthase kinase-3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway
-
Fang, X., S. Yu, J. L. Tanyi, Y. Lu, J. R. Woodgett, and G. B. Mills. 2002. Convergence of multiple signaling cascades at glycogen synthase kinase-3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway. Mol. Cell. Biol. 22:2099-2110.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2099-2110
-
-
Fang, X.1
Yu, S.2
Tanyi, J.L.3
Lu, Y.4
Woodgett, J.R.5
Mills, G.B.6
-
13
-
-
0032697808
-
Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer
-
Goetzl, E. J., H. Dolezalova, Y. Kong, Y. L. Hu, R. B. Jaffe, K. R. Kalli, and C. A. Conover. 1999. Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer. Cancer Res. 59:5370-5375.
-
(1999)
Cancer Res.
, vol.59
, pp. 5370-5375
-
-
Goetzl, E.J.1
Dolezalova, H.2
Kong, Y.3
Hu, Y.L.4
Jaffe, R.B.5
Kalli, K.R.6
Conover, C.A.7
-
15
-
-
0037131192
-
Regulation of G protein-coupled receptor signaling by scaffold proteins
-
Hall, R. A., and R. J. Lefkowitz. 2002. Regulation of G protein-coupled receptor signaling by scaffold proteins. Circ. Res. 91:672-680.
-
(2002)
Circ. Res.
, vol.91
, pp. 672-680
-
-
Hall, R.A.1
Lefkowitz, R.J.2
-
17
-
-
0032498963
-
+ exchange
-
+ exchange. Nature 392: 626-630.
-
(1998)
Nature
, vol.392
, pp. 626-630
-
-
Hall, R.A.1
Premont, R.T.2
Chow, C.W.3
Blitzer, J.T.4
Pitcher, J.A.5
Claing, A.6
Stoffel, R.H.7
Barak, L.S.8
Shenolikar, S.9
Weinman, E.J.10
Grinstein, S.11
Lefkowitz, R.J.12
-
18
-
-
0029836932
-
Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex
-
Hecht, J. H., J. A. Weiner, S. R. Post, and J. Chun. 1996. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J. Cell Biol. 135:1071-1083.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1071-1083
-
-
Hecht, J.H.1
Weiner, J.A.2
Post, S.R.3
Chun, J.4
-
19
-
-
0024520745
-
Site-directed mutagenesis by overlap extension using the polymerase chain reaction
-
Ho, S. N., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
-
(1989)
Gene
, vol.77
, pp. 51-59
-
-
Ho, S.N.1
Hunt, H.D.2
Horton, R.M.3
Pullen, J.K.4
Pease, L.R.5
-
20
-
-
0037155199
-
PDZ domains: Structural modules for protein complex assembly
-
Hung, A. Y., and M. Sheng. 2002. PDZ domains: structural modules for protein complex assembly. J. Biol. Chem. 277:5699-5702.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5699-5702
-
-
Hung, A.Y.1
Sheng, M.2
-
21
-
-
0034596054
-
+ exchanger regulatory factor 2
-
+ exchanger regulatory factor 2. J. Biol. Chem. 275:16632-16637.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16632-16637
-
-
Hwang, J.I.1
Heo, K.2
Shin, K.J.3
Kim, E.4
Yun, C.H.5
Ryu, S.H.6
Shin, H.S.7
Suh, P.G.8
-
22
-
-
0034082879
-
Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate
-
Im, D. S., C. E. Heise, M. A. Harding, S. R. George, B. F. O'Dowd, D. Theodorescu, and K. R. Lynch. 2000. Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate. Mol. Pharmacol. 57:753-759.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 753-759
-
-
Im, D.S.1
Heise, C.E.2
Harding, M.A.3
George, S.R.4
O'Dowd, B.F.5
Theodorescu, D.6
Lynch, K.R.7
-
23
-
-
0033788829
-
Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system
-
Ishii, I., J. J. Contos, N. Fukushima, and J. Chun. 2000. Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system. Mol. Pharmacol. 58:895-902.
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 895-902
-
-
Ishii, I.1
Contos, J.J.2
Fukushima, N.3
Chun, J.4
-
24
-
-
17744380191
-
TAZ: A novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
-
Kanai, F., P. A. Marignani, D. Sarbassova, R. Yagi, R. A. Hall, M. Donowitz, A. Hisaminato, T. Fujiwara, Y. Ito, L. C. Cantley, and M. B. Yaffe. 2000. TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. EMBO J. 19:6778-6791.
-
(2000)
EMBO J.
, vol.19
, pp. 6778-6791
-
-
Kanai, F.1
Marignani, P.A.2
Sarbassova, D.3
Yagi, R.4
Hall, R.A.5
Donowitz, M.6
Hisaminato, A.7
Fujiwara, T.8
Ito, Y.9
Cantley, L.C.10
Yaffe, M.B.11
-
26
-
-
1842373861
-
Phospholipase C isozymes selectively couple to specific neurotransmitter receptors
-
Kim, D., K. S. Jun, S. B. Lee, N. G. Kang, D. S. Min, Y. H. Kim, S. H. Ryu, P. G. Suh, and H. S. Shin. 1997. Phospholipase C isozymes selectively couple to specific neurotransmitter receptors. Nature 389:290-293.
-
(1997)
Nature
, vol.389
, pp. 290-293
-
-
Kim, D.1
Jun, K.S.2
Lee, S.B.3
Kang, N.G.4
Min, D.S.5
Kim, Y.H.6
Ryu, S.H.7
Suh, P.G.8
Shin, H.S.9
-
28
-
-
0037769717
-
Cyclooxygenase-2 in human pathological disease
-
Koki, A., N. K. Khan, B. M. Woerner, A. J. Dannenberg, L. Olson, K. Seibert, D. Edwards, M. Hardy, P. Isakson, and J. L. Masferrer. 2002. Cyclooxygenase-2 in human pathological disease. Adv. Exp. Med. Biol. 507:177-184.
-
(2002)
Adv. Exp. Med. Biol.
, vol.507
, pp. 177-184
-
-
Koki, A.1
Khan, N.K.2
Woerner, B.M.3
Dannenberg, A.J.4
Olson, L.5
Seibert, K.6
Edwards, D.7
Hardy, M.8
Isakson, P.9
Masferrer, J.L.10
-
29
-
-
0032491428
-
The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3
-
Lamprecht, G., E. J. Weinman, and C. H. Yun. 1998. The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3. J. Biol. Chem. 273:29972-29978.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29972-29978
-
-
Lamprecht, G.1
Weinman, E.J.2
Yun, C.H.3
-
30
-
-
0035943075
-
Oligomerization of NHERF-1 and NHERF-2 PDZ domains: Differential regulation by association with receptor carboxyl termini and by phosphorylation
-
Lau, A. G., and R. A. Hall. 2001. Oligomerization of NHERF-1 and NHERF-2 PDZ domains: differential regulation by association with receptor carboxyl termini and by phosphorylation. Biochemistry 40:8572-8580.
-
(2001)
Biochemistry
, vol.40
, pp. 8572-8580
-
-
Lau, A.G.1
Hall, R.A.2
-
31
-
-
0037142080
-
+ exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling
-
+ exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling. Nature 417:858-861.
-
(2002)
Nature
, vol.417
, pp. 858-861
-
-
Mahon, M.J.1
Donowitz, M.2
Yun, C.C.3
Segre, G.V.4
-
32
-
-
0033057582
-
Activation of the Ras-GRF/CDC25Mm exchange factor by lysophosphatidic acid
-
Mattingly, R. R., V. Saini, and I. G. Macara. 1999. Activation of the Ras-GRF/CDC25Mm exchange factor by lysophosphatidic acid. Cell. Signal 11: 603-610.
-
(1999)
Cell. Signal
, vol.11
, pp. 603-610
-
-
Mattingly, R.R.1
Saini, V.2
Macara, I.G.3
-
34
-
-
0030907226
-
Lysophosphatidic acid: G-protein signalling and cellular responses
-
Moolenaar, W. H., O. Kranenburg, F. R. Postma, and G. C. Zondag. 1997. Lysophosphatidic acid: G-protein signalling and cellular responses. Curr. Opin. Cell Biol. 9:168-173.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 168-173
-
-
Moolenaar, W.H.1
Kranenburg, O.2
Postma, F.R.3
Zondag, G.C.4
-
35
-
-
0031472910
-
Suppression of phospholipase C-β, -γ, and -δ families alters cell growth and phosphatidylinositol 4,5-bisphosphate levels
-
Nebigil, C. G. 1997. Suppression of phospholipase C-β, -γ, and -δ families alters cell growth and phosphatidylinositol 4,5-bisphosphate levels. Biochemistry 36:15949-15958.
-
(1997)
Biochemistry
, vol.36
, pp. 15949-15958
-
-
Nebigil, C.G.1
-
36
-
-
0035004560
-
Lysophosphatidic acid synthesis and release
-
Pages, C., M. F. Simon, P. Valet, and J. S. Saulnier-Blache. 2001. Lysophosphatidic acid synthesis and release. Prostaglandins Other Lipid Mediat. 64:1-10.
-
(2001)
Prostaglandins Other Lipid Mediat.
, vol.64
, pp. 1-10
-
-
Pages, C.1
Simon, M.F.2
Valet, P.3
Saulnier-Blache, J.S.4
-
37
-
-
0034927336
-
Regulation of phosphoinositide-specific phospholipase C
-
Rhee, S. G. 2001. Regulation of phosphoinositide-specific phospholipase C. Annu. Rev. Biochem. 70:281-312.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 281-312
-
-
Rhee, S.G.1
-
38
-
-
0035871981
-
Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: Overexpression of the high-affinity receptor edg4 in differentiated thyroid cancer
-
Schulte, K. M., A. Beyer, K. Kohrer, S. Oberhauser, and H. D. Roher. 2001. Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: overexpression of the high-affinity receptor edg4 in differentiated thyroid cancer. Int. J. Cancer 92:249-256.
-
(2001)
Int. J. Cancer
, vol.92
, pp. 249-256
-
-
Schulte, K.M.1
Beyer, A.2
Kohrer, K.3
Oberhauser, S.4
Roher, H.D.5
-
39
-
-
0032555484
-
Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway
-
Sheng, H., C. S. Williams, J. Shao, P. Liang, R. N. DuBois, and R. D. Beauchamp. 1998. Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. J. Biol. Chem. 273:22120-22127.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22120-22127
-
-
Sheng, H.1
Williams, C.S.2
Shao, J.3
Liang, P.4
DuBois, R.N.5
Beauchamp, R.D.6
-
40
-
-
0027214868
-
Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C-β by G protein α and βγ subunits
-
Smrcka, A. V., and P. C. Sternweis. 1993. Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C-β by G protein α and βγ subunits J. Biol. Chem. 268:9667-9674.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 9667-9674
-
-
Smrcka, A.V.1
Sternweis, P.C.2
-
41
-
-
0034670378
-
2 purinergic and M3 muscarinic acetylcholine receptors activate different phospholipase C-β isoforms that are uniquely susceptible to protein kinase C-dependent phosphorylation and inactivation
-
2 purinergic and M3 muscarinic acetylcholine receptors activate different phospholipase C-β isoforms that are uniquely susceptible to protein kinase C-dependent phosphorylation and inactivation. J. Biol. Chem. 275:39767-39772.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39767-39772
-
-
Strassheim, D.1
Williams, C.L.2
-
42
-
-
0031812221
-
Contribution of phospholipase C-β3 phosphorylation to the rapid attenuation of opioid-activated phosphoinositide response
-
Strassheim, D., P. Y. Law, and H. H. Loh. 1998. Contribution of phospholipase C-β3 phosphorylation to the rapid attenuation of opioid-activated phosphoinositide response. Mol. Pharmacol. 53:1047-1053.
-
(1998)
Mol. Pharmacol.
, vol.53
, pp. 1047-1053
-
-
Strassheim, D.1
Law, P.Y.2
Loh, H.H.3
-
43
-
-
0035475318
-
Expanding the role of NHERF, a PDZ-domain containing protein adapter, to growth regulation
-
Voltz, J. W., E. J. Weinman, and S. Shenolikar. 2001. Expanding the role of NHERF, a PDZ-domain containing protein adapter, to growth regulation. Oncogene 20:6309-6314.
-
(2001)
Oncogene
, vol.20
, pp. 6309-6314
-
-
Voltz, J.W.1
Weinman, E.J.2
Shenolikar, S.3
-
44
-
-
0032080043
-
Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFFR)
-
Wang, S., R. W. Raab, P. J. Schatz, W. B. Guggino, and M. Li. 1998. Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFFR). FEBS Lett. 427:103-108.
-
(1998)
FEBS Lett.
, vol.427
, pp. 103-108
-
-
Wang, S.1
Raab, R.W.2
Schatz, P.J.3
Guggino, W.B.4
Li, M.5
-
45
-
-
0033834085
-
Signal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA
-
Weinman, E. J., C. Minkoff, and S. Shenolikar. 2000. Signal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA. Am. J. Physiol. Renal Physiol. 279:F393-F399.
-
(2000)
Am. J. Physiol. Renal Physiol.
, vol.279
-
-
Weinman, E.J.1
Minkoff, C.2
Shenolikar, S.3
-
46
-
-
0032569235
-
Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers
-
Xu, Y., Z. Shen, D. W. Wiper, M. Wu, R. E. Morton, P. Elson, A. W. Kennedy, J. Belinson, M. Markman, and G. Casey. 1998. Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers. JAMA 280: 719-723.
-
(1998)
JAMA
, vol.280
, pp. 719-723
-
-
Xu, Y.1
Shen, Z.2
Wiper, D.W.3
Wu, M.4
Morton, R.E.5
Elson, P.6
Kennedy, A.W.7
Belinson, J.8
Markman, M.9
Casey, G.10
-
47
-
-
0037040897
-
+ exchanger isoform 3 revisited: The roles of SGK1 and NHERF2
-
+ exchanger isoform 3 revisited: the roles of SGK1 and NHERF2. J. Biol. Chem. 277:7676-7683.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7676-7683
-
-
Yun, C.C.1
Chen, Y.2
Lang, F.3
|