Protective effect of PNU-120596, a selective alpha7 nicotinic acetylcholine receptor-positive allosteric modulator, on myocardial ischemia-reperfusion injury in rats

Journal of Cardiovascular Pharmacology

Volumn 59, Issue 6, 2012, Pages 507-513

  Li, Hui ^a   Zhang, Zong Ze ^a   Zhan, Jia ^a   He, Xiang Hu ^a   Song, Xue Min ^a   Wang, Yan Lin ^a  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

alpha7 nicotinic acetylcholine receptor; cytokines; inflammation; myocardial reperfusion injury; PNU 120596

Indexed keywords

ALPHA BUNGAROTOXIN; CARDIAC AGENT; CREATINE KINASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MALONALDEHYDE; NICOTINIC RECEPTOR; PNU 120596; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; CYTOKINE PRODUCTION; DRUG EFFECT; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; REVIEW;

ALLOSTERIC REGULATION; ANIMALS; BUNGAROTOXINS; CYTOKINES; DISEASE MODELS, ANIMAL; INFLAMMATION; ISOXAZOLES; LIPID PEROXIDATION; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; NF-KAPPA B; NICOTINIC AGONISTS; PHENYLUREA COMPOUNDS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC;

EID: 84862188055     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0b013e31824c86c3     Document Type: Review

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