-
2
-
-
0242492756
-
Virtual drug discovery and development for neglected diseases through public private partnerships
-
10.1038/nrd1230, 14668812
-
Nwaka S, Ridley RG. Virtual drug discovery and development for neglected diseases through public private partnerships. Nat Rev Drug Discov 2003, 2:919-928. 10.1038/nrd1230, 14668812.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 919-928
-
-
Nwaka, S.1
Ridley, R.G.2
-
3
-
-
33750531864
-
Innovative lead discovery strategies for tropical diseases
-
10.1038/nrd2144, 17080030
-
Nwaka S, Hudson A. Innovative lead discovery strategies for tropical diseases. Nat Rev Drug Discov 2006, 5:941-955. 10.1038/nrd2144, 17080030.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 941-955
-
-
Nwaka, S.1
Hudson, A.2
-
4
-
-
11144311139
-
Lessons from natural molecules
-
10.1038/nature03194, 15602548
-
Clardy J, Walsh C. Lessons from natural molecules. Nature 2004, 432:829-837. 10.1038/nature03194, 15602548.
-
(2004)
Nature
, vol.432
, pp. 829-837
-
-
Clardy, J.1
Walsh, C.2
-
5
-
-
0035179157
-
Antiparasitic properties of medicinal plants and other naturally occurring products
-
Tagboto S, Townson S. Antiparasitic properties of medicinal plants and other naturally occurring products. Adv Parasitol 2001, 50:199-295.
-
(2001)
Adv Parasitol
, vol.50
, pp. 199-295
-
-
Tagboto, S.1
Townson, S.2
-
6
-
-
23044511375
-
Ethnopharmacology and systems biology: A perfect holistic match
-
10.1016/j.jep.2005.05.033, 16026949
-
Verpoorte R, Choi YH, Kim HK. Ethnopharmacology and systems biology: A perfect holistic match. J Ethnopharmacol 2005, 100:53-56. 10.1016/j.jep.2005.05.033, 16026949.
-
(2005)
J Ethnopharmacol
, vol.100
, pp. 53-56
-
-
Verpoorte, R.1
Choi, Y.H.2
Kim, H.K.3
-
7
-
-
77949688527
-
Antiplasmodial activity ofAjuga bracteosaagainst Plasmodium berghei infected BALB/c mice
-
Chandel S, Bagai U. Antiplasmodial activity ofAjuga bracteosaagainst Plasmodium berghei infected BALB/c mice. Indian J Med Res 2010, 131:440-444.
-
(2010)
Indian J Med Res
, vol.131
, pp. 440-444
-
-
Chandel, S.1
Bagai, U.2
-
9
-
-
1542791551
-
Medicinal Plant Diversity in the Flora of Saudi Arabia 1: a Report on Seven Plant Families
-
10.1016/j.fitote.2003.12.012, 15030919
-
Atiqur-Rahman M, Mossa JS, Al-Said MS, Al-Yahya MA. Medicinal Plant Diversity in the Flora of Saudi Arabia 1: a Report on Seven Plant Families. Fitoterapia 2004, 75:149-161. 10.1016/j.fitote.2003.12.012, 15030919.
-
(2004)
Fitoterapia
, vol.75
, pp. 149-161
-
-
Atiqur-Rahman, M.1
Mossa, J.S.2
Al-Said, M.S.3
Al-Yahya, M.A.4
-
12
-
-
0019924883
-
Repertory of drugs and medicinal plants of Yemen
-
10.1016/0378-8741(82)90073-3, 7109666
-
Fleurentin J, Pelt JM. Repertory of drugs and medicinal plants of Yemen. J Ethnopharmacol 1982, 6:85-108. 10.1016/0378-8741(82)90073-3, 7109666.
-
(1982)
J Ethnopharmacol
, vol.6
, pp. 85-108
-
-
Fleurentin, J.1
Pelt, J.M.2
-
14
-
-
33745435902
-
Anti-infective potential of natural products: How to develop a strongerin vitroproof-of-concept
-
10.1016/j.jep.2006.04.003, 16698208
-
Cos P, Vlietinck AJ, Berghe DV, Maes L. Anti-infective potential of natural products: How to develop a strongerin vitroproof-of-concept. J Ethnopharmacol 2006, 106:290-302. 10.1016/j.jep.2006.04.003, 16698208.
-
(2006)
J Ethnopharmacol
, vol.106
, pp. 290-302
-
-
Cos, P.1
Vlietinck, A.J.2
Berghe, D.V.3
Maes, L.4
-
15
-
-
0027281689
-
Parasite lactate dehydrogenase as an assay forPlasmodium falciparumdrug sensitivity
-
Makler MT, Ries JM, Williams JA, Bancroft JE, Piper RC, Hinrichs DJ. Parasite lactate dehydrogenase as an assay forPlasmodium falciparumdrug sensitivity. Am J Trop Med Hyg 1993, 48:739-741.
-
(1993)
Am J Trop Med Hyg
, vol.48
, pp. 739-741
-
-
Makler, M.T.1
Ries, J.M.2
Williams, J.A.3
Bancroft, J.E.4
Piper, R.C.5
Hinrichs, D.J.6
-
16
-
-
0024948840
-
Continuous cultivation ofTrypanosoma bruceiblood stream forms in a medium containing a low concentration of serum protein without feeder cell layers
-
10.2307/3282883, 2614608
-
Hirumi H, Hirumi K. Continuous cultivation ofTrypanosoma bruceiblood stream forms in a medium containing a low concentration of serum protein without feeder cell layers. J Parasitol 1989, 75:985-989. 10.2307/3282883, 2614608.
-
(1989)
J Parasitol
, vol.75
, pp. 985-989
-
-
Hirumi, H.1
Hirumi, K.2
-
17
-
-
0030612893
-
The Alamar Blue asssay to determine drug sensitivity of African trypanosomes (T. b. rhodesiense, T. b. gambiense)in vitro
-
Raz B, Iten M, Grether-Buhler Y, Kaminsky R, Brun R. The Alamar Blue asssay to determine drug sensitivity of African trypanosomes (T. b. rhodesiense, T. b. gambiense)in vitro. Acta Trop 1997, 68:2592-2597.
-
(1997)
Acta Trop
, vol.68
, pp. 2592-2597
-
-
Raz, B.1
Iten, M.2
Grether-Buhler, Y.3
Kaminsky, R.4
Brun, R.5
-
18
-
-
0029861640
-
Efficient technique for screening drugs for activity againstTrypanosoma cruziusing parasites expressing beta-galactosidase
-
163582, 8913471
-
Buckner FS, Verlinde CL, La Flamme AC, Van Voorhis WC. Efficient technique for screening drugs for activity againstTrypanosoma cruziusing parasites expressing beta-galactosidase. Antimicrob Agents Chemother 1996, 40:2592-2597. 163582, 8913471.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 2592-2597
-
-
Buckner, F.S.1
Verlinde, C.L.2
La Flamme, A.C.3
Van Voorhis, W.C.4
-
19
-
-
0026321846
-
Antiprotozoal agents from plant sources
-
10.1055/s-2006-960017, 17226121
-
Phillipson JD, Wright CW. Antiprotozoal agents from plant sources. Planta Med 1991, 57:53-59. 10.1055/s-2006-960017, 17226121.
-
(1991)
Planta Med
, vol.57
, pp. 53-59
-
-
Phillipson, J.D.1
Wright, C.W.2
-
20
-
-
0035543633
-
Plant natural products with leishmanicidal activity
-
Chan-Bacab MJ, Peña-Rodríguez LM. Plant natural products with leishmanicidal activity. Nat Prod Rep 2001, 18:674-688.
-
(2001)
Nat Prod Rep
, vol.18
, pp. 674-688
-
-
Chan-Bacab, M.J.1
Peña-Rodríguez, L.M.2
-
21
-
-
2542446356
-
Comparative activities of the triterpene saponin Maesabalide-III and liposomal amphotericin-B (AmBisome) againstLeishmania donovaniin hamsters
-
10.1128/AAC.48.6.2056-2060.2004, 415622, 15155199
-
Maes L, Germonprez N, Quirijnen L, Van Puyvelde L, Cos P, Vanden Berghe D. Comparative activities of the triterpene saponin Maesabalide-III and liposomal amphotericin-B (AmBisome) againstLeishmania donovaniin hamsters. Antimicrob Agents Chemother 2004, 48:2056-2060. 10.1128/AAC.48.6.2056-2060.2004, 415622, 15155199.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2056-2060
-
-
Maes, L.1
Germonprez, N.2
Quirijnen, L.3
Van Puyvelde, L.4
Cos, P.5
Vanden Berghe, D.6
-
22
-
-
19944424798
-
A review of natural products with antileishmanial activity
-
10.1016/j.phymed.2003.10.006, 16008131
-
Rocha LG, Almeida JRGS, Macêdo RO, Barbosa-Filho JM. A review of natural products with antileishmanial activity. Phytomedicine 2005, 12:514-535. 10.1016/j.phymed.2003.10.006, 16008131.
-
(2005)
Phytomedicine
, vol.12
, pp. 514-535
-
-
Rocha, L.G.1
Almeida, J.R.G.S.2
Macêdo, R.O.3
Barbosa-Filho, J.M.4
-
23
-
-
77956223508
-
Antiplasmodial triterpenoids from the fruits of neem,Azadirachta indica
-
10.1021/np100325q, 20669933
-
Chianese G, Yerbanga SR, Lucantoni L, Habluetzel A, Basilico N, Taramelli D, Fattorusso E, Taglialatela-Scafati O. Antiplasmodial triterpenoids from the fruits of neem,Azadirachta indica. J Nat Prod 2010, 73:1448-1452. 10.1021/np100325q, 20669933.
-
(2010)
J Nat Prod
, vol.73
, pp. 1448-1452
-
-
Chianese, G.1
Yerbanga, S.R.2
Lucantoni, L.3
Habluetzel, A.4
Basilico, N.5
Taramelli, D.6
Fattorusso, E.7
Taglialatela-Scafati, O.8
-
24
-
-
77956044819
-
Screening of medicinal plants againstLeishmania amazonensis
-
10.3109/13880200903485729, 20731558
-
García M, Monzote L, Montalvo AM, Scull R. Screening of medicinal plants againstLeishmania amazonensis. Pharm Biol 2010, 48:1053-1058. 10.3109/13880200903485729, 20731558.
-
(2010)
Pharm Biol
, vol.48
, pp. 1053-1058
-
-
García, M.1
Monzote, L.2
Montalvo, A.M.3
Scull, R.4
-
25
-
-
77954687214
-
Recent developments in research on terrestrial plants used for the treatment of malaria
-
10.1039/c002196m, 20532364
-
Wright CW. Recent developments in research on terrestrial plants used for the treatment of malaria. Nat Prod Rep 2010, 27:961-968. 10.1039/c002196m, 20532364.
-
(2010)
Nat Prod Rep
, vol.27
, pp. 961-968
-
-
Wright, C.W.1
-
26
-
-
78649430749
-
Antiprotozoal activity of drimane and coloratane sesquiterpenes towardsTrypanosoma brucei rhodesienseandPlasmodium falciparum in vitro
-
10.1002/ptr.3126, 20878696
-
Wube AA, Bucar F, Gibbons S, Asres K, Rattray L, Croft SL. Antiprotozoal activity of drimane and coloratane sesquiterpenes towardsTrypanosoma brucei rhodesienseandPlasmodium falciparum in vitro. Phytother Res 2010, 24:1468-1472. 10.1002/ptr.3126, 20878696.
-
(2010)
Phytother Res
, vol.24
, pp. 1468-1472
-
-
Wube, A.A.1
Bucar, F.2
Gibbons, S.3
Asres, K.4
Rattray, L.5
Croft, S.L.6
-
27
-
-
77957264578
-
In VitroActivities of Plant Extracts from Saudi Arabia against Malaria, Leishmaniasis, Sleeping Sickness and Chagas Disease
-
10.1002/ptr.3108, 20127723
-
Abdel-Sattar E, Maes L, Salama MM. In VitroActivities of Plant Extracts from Saudi Arabia against Malaria, Leishmaniasis, Sleeping Sickness and Chagas Disease. Phytother Res 2010, 24:1322-1328. 10.1002/ptr.3108, 20127723.
-
(2010)
Phytother Res
, vol.24
, pp. 1322-1328
-
-
Abdel-Sattar, E.1
Maes, L.2
Salama, M.M.3
-
28
-
-
38749090587
-
Evaluation of Senegalese plants used in malaria treatment: focus onChrozophora senegalensis
-
Benoit-Vical F, Soh PN, Saléry M, Harguem L, Poupat C, Nongonierma R. Evaluation of Senegalese plants used in malaria treatment: focus onChrozophora senegalensis. J Ethnopharmacol 2008, 28:43-48.
-
(2008)
J Ethnopharmacol
, vol.28
, pp. 43-48
-
-
Benoit-Vical, F.1
Soh, P.N.2
Saléry, M.3
Harguem, L.4
Poupat, C.5
Nongonierma, R.6
-
29
-
-
0034753599
-
Evaluation of the flora of Puerto Rico forin vitroantiplasmodial and antimycobacterial activities
-
10.1002/ptr.880, 11746852
-
Antoun MD, Ramos Z, Vazques J, Oquendo I, Proctor GR, Gerena L, Franzblau SG. Evaluation of the flora of Puerto Rico forin vitroantiplasmodial and antimycobacterial activities. Phytother Res 2001, 15:638-642. 10.1002/ptr.880, 11746852.
-
(2001)
Phytother Res
, vol.15
, pp. 638-642
-
-
Antoun, M.D.1
Ramos, Z.2
Vazques, J.3
Oquendo, I.4
Proctor, G.R.5
Gerena, L.6
Franzblau, S.G.7
-
30
-
-
0036969333
-
Antimalarial agents from plants. III. Trichothecenes fromFicus fistulosaandRhaphidophora decursiva
-
10.1055/s-2002-36350, 12494335
-
Zhang HJ, Tamez PA, Aydogmus Z, Tan GT, Saikawa Y, Hashimoto K, Nakata M, Hung NV, Xuan le T, Cuong NM, Soejarto DD, Pezzuto JM, Fong HH. Antimalarial agents from plants. III. Trichothecenes fromFicus fistulosaandRhaphidophora decursiva. Planta Med 2002, 68:1088-1091. 10.1055/s-2002-36350, 12494335.
-
(2002)
Planta Med
, vol.68
, pp. 1088-1091
-
-
Zhang, H.J.1
Tamez, P.A.2
Aydogmus, Z.3
Tan, G.T.4
Saikawa, Y.5
Hashimoto, K.6
Nakata, M.7
Hung, N.V.8
Xuan le, T.9
Cuong, N.M.10
Soejarto, D.D.11
Pezzuto, J.M.12
Fong, H.H.13
-
31
-
-
0037296813
-
In vitroantiplasmodial activity of some plants used in Kisii, Kenya against malaria and their chloroquine potentiation effects
-
10.1016/S0378-8741(02)00327-6, 12648820
-
Muregi FW, Chhabra SC, Njagi EN, Lang'at-Thoruwa CC, Njue WM, Orago AS, Omar SA, Ndiege IO. In vitroantiplasmodial activity of some plants used in Kisii, Kenya against malaria and their chloroquine potentiation effects. J Ethnopharmacol 2003, 84:235-239. 10.1016/S0378-8741(02)00327-6, 12648820.
-
(2003)
J Ethnopharmacol
, vol.84
, pp. 235-239
-
-
Muregi, F.W.1
Chhabra, S.C.2
Njagi, E.N.3
Lang'at-Thoruwa, C.C.4
Njue, W.M.5
Orago, A.S.6
Omar, S.A.7
Ndiege, I.O.8
-
32
-
-
33645992430
-
Antimalarial compounds fromGrewia bilamellata
-
10.1021/np050313d, 16562832
-
Ma C, Zhang HJ, Tan GT, Hung NV, Cuong NM, Soejarto DD, Fong HH. Antimalarial compounds fromGrewia bilamellata. J Nat Prod 2006, 69:346-350. 10.1021/np050313d, 16562832.
-
(2006)
J Nat Prod
, vol.69
, pp. 346-350
-
-
Ma, C.1
Zhang, H.J.2
Tan, G.T.3
Hung, N.V.4
Cuong, N.M.5
Soejarto, D.D.6
Fong, H.H.7
-
33
-
-
77649191020
-
Antimalarial herbal remedies of Msambweni, Kenya
-
Nguta JM, Mbaria JM, Gakuya DW, Gathumbi PK, Kiama SG. Antimalarial herbal remedies of Msambweni, Kenya. J Ethnopharmacol 2010, 24:424-432.
-
(2010)
J Ethnopharmacol
, vol.24
, pp. 424-432
-
-
Nguta, J.M.1
Mbaria, J.M.2
Gakuya, D.W.3
Gathumbi, P.K.4
Kiama, S.G.5
-
34
-
-
33749434804
-
Antiparasitic activity of twoLavandulaessential oils againstGiardia duodenalis,Trichomonas vaginalisandHexamita inflata
-
10.1007/s00436-006-0234-8, 16741725
-
Moon T, Wilkinson JM, Cavanagh HM. Antiparasitic activity of twoLavandulaessential oils againstGiardia duodenalis,Trichomonas vaginalisandHexamita inflata. Parasitol Res 2006, 99:722-728. 10.1007/s00436-006-0234-8, 16741725.
-
(2006)
Parasitol Res
, vol.99
, pp. 722-728
-
-
Moon, T.1
Wilkinson, J.M.2
Cavanagh, H.M.3
-
35
-
-
78049275383
-
Antibacterial activity of essential oils of some Algerian aromatic plants against multidrug resistant bacteria
-
Mohamed SB, Eddine AD. Antibacterial activity of essential oils of some Algerian aromatic plants against multidrug resistant bacteria. J Essen Oil-Bear Plants 2010, 13:362-370.
-
(2010)
J Essen Oil-Bear Plants
, vol.13
, pp. 362-370
-
-
Mohamed, S.B.1
Eddine, A.D.2
-
36
-
-
50449086895
-
Brazilian flora extracts as source of novel antileishmanial and antifungal compounds
-
10.1590/S0074-02762008000500006, 18797756
-
Tempone AG, Sartorelli P, Teixeira D, Prado FO, Calixto IA, Lorenzi H, Melhem MS. Brazilian flora extracts as source of novel antileishmanial and antifungal compounds. Mem Inst Oswaldo Cruz 2008, 103:443-449. 10.1590/S0074-02762008000500006, 18797756.
-
(2008)
Mem Inst Oswaldo Cruz
, vol.103
, pp. 443-449
-
-
Tempone, A.G.1
Sartorelli, P.2
Teixeira, D.3
Prado, F.O.4
Calixto, I.A.5
Lorenzi, H.6
Melhem, M.S.7
-
37
-
-
27944462676
-
Plectranthus: A review of ethnobotanical uses
-
10.1016/j.jep.2005.09.011, 16289602
-
Lukhoba CW, Simmonds MSJ, Paton AJ. Plectranthus: A review of ethnobotanical uses. J Ethnopharmacol 2006, 103:1-24. 10.1016/j.jep.2005.09.011, 16289602.
-
(2006)
J Ethnopharmacol
, vol.103
, pp. 1-24
-
-
Lukhoba, C.W.1
Simmonds, M.S.J.2
Paton, A.J.3
-
38
-
-
44649118747
-
Antiplasmodial activities of some abietane diterpenes from the leaves of fivePlectranthusspecies
-
Van Zyl RL, Khan F, Edwards TJ, Drewes SE. Antiplasmodial activities of some abietane diterpenes from the leaves of fivePlectranthusspecies. S Afri J Sci 2008, 104:62-64.
-
(2008)
S Afri J Sci
, vol.104
, pp. 62-64
-
-
Van Zyl, R.L.1
Khan, F.2
Edwards, T.J.3
Drewes, S.E.4
-
39
-
-
78651404679
-
Antiplasmodial and cytotoxic activities of medicinal plants traditionally used in the village of Kiohima, Uganda
-
10.1016/j.jep.2010.11.013, 21075191
-
Lacroix D, Prado S, Kamoga D, Kasenene J, Namukobe J, Krief S, Dumontet V, Mouray E, Bodo B, Brunois F. Antiplasmodial and cytotoxic activities of medicinal plants traditionally used in the village of Kiohima, Uganda. J Ethnopharmacol 2011, 133:850-855. 10.1016/j.jep.2010.11.013, 21075191.
-
(2011)
J Ethnopharmacol
, vol.133
, pp. 850-855
-
-
Lacroix, D.1
Prado, S.2
Kamoga, D.3
Kasenene, J.4
Namukobe, J.5
Krief, S.6
Dumontet, V.7
Mouray, E.8
Bodo, B.9
Brunois, F.10
-
40
-
-
78650037196
-
Evaluating biological activities of the seed extracts fromTagetes minutaL. found in Northern Pakistan
-
Shahzadi I, Hassan A, Khan UW, Shah MM. Evaluating biological activities of the seed extracts fromTagetes minutaL. found in Northern Pakistan. J Med Plants Res 2010, 4:2108-2112.
-
(2010)
J Med Plants Res
, vol.4
, pp. 2108-2112
-
-
Shahzadi, I.1
Hassan, A.2
Khan, U.W.3
Shah, M.M.4
-
41
-
-
2342664601
-
In vitroantiplasmodial activity of medicinal plants native to or naturalised in South Africa
-
10.1016/j.jep.2004.02.011, 15137999
-
Clarkson C, Maharaj VJ, Crouch NR, Grace OM, Pillay P, Matsabisa MG, Bhagwandin N, Smith PJ, Folb PI. In vitroantiplasmodial activity of medicinal plants native to or naturalised in South Africa. J Ethnopharmacol 2004, 92:177-191. 10.1016/j.jep.2004.02.011, 15137999.
-
(2004)
J Ethnopharmacol
, vol.92
, pp. 177-191
-
-
Clarkson, C.1
Maharaj, V.J.2
Crouch, N.R.3
Grace, O.M.4
Pillay, P.5
Matsabisa, M.G.6
Bhagwandin, N.7
Smith, P.J.8
Folb, P.I.9
-
42
-
-
53449100940
-
Investigating South African plants as a source of new antimalarial drugs
-
10.1016/j.jep.2008.07.003, 18687395
-
Pillay P, Maharaj VJ, Smith PJ. Investigating South African plants as a source of new antimalarial drugs. J Ethnopharmacol 2008, 119:438-454. 10.1016/j.jep.2008.07.003, 18687395.
-
(2008)
J Ethnopharmacol
, vol.119
, pp. 438-454
-
-
Pillay, P.1
Maharaj, V.J.2
Smith, P.J.3
-
43
-
-
70450186312
-
Bioactive natural products derived from the East African flora
-
10.1039/b906089h, 19936385
-
Magadula JJ, Erasto P. Bioactive natural products derived from the East African flora. Nat Prod Rep 2009, 26:1535-1554. 10.1039/b906089h, 19936385.
-
(2009)
Nat Prod Rep
, vol.26
, pp. 1535-1554
-
-
Magadula, J.J.1
Erasto, P.2
-
44
-
-
3042819882
-
Natural products active against African trypanosomes: a step towards new drugs
-
10.1039/b311021b, 15162223
-
Hoet S, Opperdoes F, Brun R, Quetin-Leclercq J. Natural products active against African trypanosomes: a step towards new drugs. Nat Prod Rep 2004, 21:353-364. 10.1039/b311021b, 15162223.
-
(2004)
Nat Prod Rep
, vol.21
, pp. 353-364
-
-
Hoet, S.1
Opperdoes, F.2
Brun, R.3
Quetin-Leclercq, J.4
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