Antimalarial agents from plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva

Planta Medica

Volumn 68, Issue 12, 2002, Pages 1088-1091

  Zhang, Hong Jie ^a   Tamez, Pamela A ^a   Aydogmus, Zeynep ^a   Tan, Ghee Teng ^a   Saikawa, Yoko ^b   Hashimoto, Kimiko ^b   Nakata, Masaya ^b   Hung, Nguyen Van ^c   Xuan, Le Thi ^c   Cuong, Nguyen Manh ^d   Soejarto, D Doel ^a   Pezzuto, John M ^a   Fong, Harry H S ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b KEIO UNIVERSITY   (Japan)

^c INSTITUTE OF CHEMISTRY   (Viet Nam)

^d Cuc Phuong National Park   (Viet Nam)

Author keywords

Antimalarial activity; Araceae; Bioassay directed fractionation; Ficus fistulosa; Moraceae; Rhaphidophora decursiva; Roridin E; Trichothecene sesquiterpenoids; Verrucarin L acetate

Indexed keywords

3 INDOLECARBALDEHYDE; 3,4,5 TRIMETHOXYBENZYL ALCOHOL; 3ALPHA HYDROXYISOHOP 22(29) EN 24 IOC ACID; 3BETA GLUCOSITOSTEROL; ALPHA METHYL 3,4,5 TRIMETHOXYBEZYL ALCOHOL; ANTIMALARIAL AGENT; ARTEMISININ; AURANTIAMIDE ACETATE; CHLOROQUINE; CORYDALDINE; MACROCYCLIC COMPOUND; PALMANINE; QUININE; RORIDIN E; SATRATOXIN H; SATRATOXIN H 12',13' DIACETATE; SATRATOXIN H 13' ACETATE; SESQUITERPENOID; TRICHOTHECENE DERIVATIVE; UNCLASSIFIED DRUG; VERRUCARIN ACETATE;

ANTIMALARIAL ACTIVITY; ARTICLE; BARK; BIOASSAY; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; FICUS; FICUS FISTULOSA; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PLANT LEAF; PLASMODIUM FALCIPARUM; RHAPHIDOPHORA DECURSIVA;

ANIMALS; ANTIMALARIALS; ARACEAE; FICUS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PLANT BARK; PLANT EXTRACTS; PLANT LEAVES; PLASMODIUM FALCIPARUM; TRICHOTHECENES;

ARACEAE; CINCHONA PUBESCENS; MORACEAE; PLASMODIUM FALCIPARUM; RHAPHIDOPHORA; RHAPHIDOPHORA DECURSIVA;

EID: 0036969333     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-36350     Document Type: Article

References (21)

1. Rosenthal JP, Beck D, Bhat A, Biswas J, Brady L, Bridbord K et al. Combining high risk science with ambitious social and economic goals. Pharmaceutical Biology 1999; 37 (Supplement): 6-21
2. Soejarto DD, Gyllenhaal C, Regalado JC, Pezzuto JM, Fong HHS, Tan GT et al. Studies on biodiversity of Vietnam and Laos: the UIC-based ICBG program. Pharmaceutical Biology 1999; 37 (Supplement): 100-13
3. Tuyen NV; Kim DSHL, Fong HHS, Soejarto DD, Khanh TC, Tri MV et al. Structure elucidation of two triterpenoids from Ficus fistulosa. Phytochemistry 1998; 50: 467-9
4. Zhang HJ, Tamez PA, Hoang VD, Tan GT, Hung NV, Xuan LT et al. Antimalarial compounds from Rhaphidophora decursiva. Journal of Natural Products 2001; 64: 772-7
5. Zhang HJ, Qiu SX, Tamez PA, Tan GT, Aydogmus Z, Hung NV et al. Antimalarial agents from plants. II. Decursivine, a new antimalarial indole alkaloid from Rhaphidophora decursiva. Pharmaceutical Biology, 2002; 40: in press
6. Kitajima J, Kimizuka K, Arai M, Tanaka Y. Constituents of Ficus pumila leaves. Chemical Pharmaceutical Bulletin 1998; 46: 1647-9
7. 13C-NMR assignments of stigma-5-en-3-O-β-glucoside and its acetyl derivative. Magnetic Resonance Chemistry 2001; 39: 399-405
8. Jarvis BB, Midiwo JO, DeSilva T, Mazzola EP. Verrucarin L, a new macrocyclic trichothecene. Journal of Antibiotics 1981; 34: 120-1
9. Patra A, Mukhopadhyay PK. Carbon-13 NMR spectra of some benzene derivatives. Journal of Indian Chemical Society 1983; 60: 265-8
10. Koul S, Koul JL, Taneja SC, Dhar KL, Jamwal DS, Singh K, et al. Structure-activity relationship of piperine and its synthetic analogues for their inhibitory potentials of rat hepatic microsomal constitutive and inducible cytochrome P450 activities. Biorganic and Medicinal Chemistry 2000; 8: 251-68
11. Kametani T, Ohsawa T, Ihara M, Fukumoto K. Studies on the syntheses of heterocyclic compounds. DCCLV. Iminoketene cycloaddition. (4). Alternative syntheses of 5,6,7,8-tetrahydro-2,3-dimethoxy-8-oxoisoquinolo[1,2-b]quinazoline and rutecarpine. Chemical Pharmaceutical Bulletin 1978; 26: 922-6
12. Valencia E, Weiss I, Firdous S, Freyer AJ, Shamma M. The isoindolobenzazepine alkaloids. Tetrahedron 1984; 40: 3957-62
13. 13C-NMR chemical shift assignments for some 1H-pyrrole-2-carboxylic acid derivatives. Magnetic Resonance Chemistry 1986; 24: 827-33
14. Wahidulla S, D'Souza L, Kamat SY. Dipeptides from the red alga Acanthophora spicifera. Phytochemistry 1991; 30: 3323-5
15. Saikawa Y, Okamoto H, Inui T, Makabe M, Okuno T, Suda T et al. Toxic principles of a poisonous mushroom Podostroma cornu-damae. Tetrahedron 2001; 57: 8277-81
16. Isaka M, Punya J, Lertwerawat Y, Tanticharoen M, Thebtaranonth Y. Antimalarial activity of macrocyclic trichothecenes isolated from the fungus Myrothecium verrucaria. Journal of Natural Products 1999; 62: 329-31
17. Tamm C, Breitenstein W. The biosynthesis of trichothecene mycotoxins: Study of Secondary Metabolism. Editor(s): Steyn PS. Academic Press, New York: 1980: 69-104
18. Jarvis BB, Midiwo JO, Bean GA, Aboul-Nasr MB, Barros CS. The mystery of trichothecene antibiotics in Baccharis species. Journal of Natural Products 1988; 51: 736-44
19. Ueno Y, Hosoya M, Morita Y, Ueno I, Takashi T. Inhibition of the protein synthesis in rabbit reticulocyte by nivalenol, a toxic principle isolated from Fusarium nivale-growing rice. Journal of Biochemistry 1968; 64: 479-85
20. Cundliffe E, Davies JE. Inhibition of initiation, elongation, and termination of eukaryotic protein synthesis by trichothecene fungal toxins. Antimicrobial Agents and Chemotherapy 1977: 11: 491-9
21. Hernandez F, Cannon M. Inhibition of protein synthesis in Saccharomyces cerevisiae by the 12,13-epoxytrichothecenes trichodermol, diacetoxyscirpenol and verrucarin A: Reversibility of the effects. Journal of Antibiotics 1982; 35: 875-81