Antiprotozoal activity of drimane and coloratane sesquiterpenes towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro

Phytotherapy Research

Volumn 24, Issue 10, 2010, Pages 1468-1472

  Wube, Abraham Abebe ^a   Bucar, Franz ^a   Gibbons, Simon ^b   Asres, Kaleab ^c   Rattray, Lauren ^d   Croft, Simon L ^d  

^a UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c ADDIS ABABA UNIVERSITY   (Ethiopia)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

antiplasmodial; antitrypanosomal; coloratane sesquiterpenes; drimane sesquiterpenes; Warburgia ugandensis

Indexed keywords

11ALPHA HYDROXYMUZIGADIOLIDE; 4 (13), 7 COLORATADIENE 12,11 OLIDE; 6ALPHA,9ALPHA DIHYDROXY 4 (13), 7 COLORATADIENE 11,12 DIAL; 7ALPHA HYDROXY 8 DRIMEN 11,12 OLIDE; 7BETA HYDROXY 4 (13), 7 COLORATADIEN 11,12 OLIDE; ANTIPROTOZOAL AGENT; ANTITRYPANOSOMAL AGENT; CHLOROQUINE; CINNAMOLIDE; CINNAMOLIDE 3 BETA ACETATE; MUKAADIAL; MUZIGADIAL; MUZIGADIOLIDE; SESQUITERPENE; UGANDENSIDIAL; UGANDENSOLIDE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG RESISTANCE; DRUG SENSITIVITY; IC 50; IN VITRO STUDY; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; TRYPANOSOMA RHODESIENSE; TRYPANOSOMIASIS;

ANGIOSPERMS; ANTIPROTOZOAL AGENTS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PLANT BARK; PLANT EXTRACTS; PLANTS, MEDICINAL; PLASMODIUM FALCIPARUM; SESQUITERPENES; TRYPANOSOMA BRUCEI RHODESIENSE;

CANELLACEAE; PLASMODIUM FALCIPARUM; TRYPANOSOMA BRUCEI RHODESIENSE; WARBURGIA UGANDENSIS;

EID: 78649430749     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3126     Document Type: Article

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