Nanostructuration strategies to enhance microelectrode array (MEA) performance for neuronal recording and stimulation

Journal of Physiology Paris

Volumn 106, Issue 3-4, 2012, Pages 137-145

  Heim, Matthias ^a   Yvert, Blaise ^b,c   Kuhn, Alexander ^a  

^a INSTITUT DES SCIENCES MOLÉCULAIRES   (France)

^b UMR 5287   (France)

^c UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Electrochemistry; Microelectrode array; Nanostructures; Neuronal recording; Neuronal stimulation; Porous electrodes

Indexed keywords

CARBON NANOTUBE; NANOMATERIAL; POLYMER;

ARTICLE; CONTROLLED STUDY; ELECTRODE; FILM; GENERAL DEVICE; IMMOBILIZATION; IMPEDANCE; IN VITRO STUDY; IN VIVO STUDY; MEASUREMENT; MICROELECTRODE; MICROELECTRODE ARRAY; NERVE CELL; NERVE STIMULATION; NOISE; RECORDING; SENSITIVITY AND SPECIFICITY; SURFACE CHARGE;

ANIMALS; ELECTRIC IMPEDANCE; ELECTRODES, IMPLANTED; EQUIPMENT DESIGN; HYDROGEL; IRIDIUM; MICROELECTRODES; NANOTUBES, CARBON; NEURONS; PLATINUM; RATS;

EID: 84862161627     PISSN: 09284257     EISSN: 17697115     Source Type: Journal    
DOI: 10.1016/j.jphysparis.2011.10.001     Document Type: Article

References (118)

1. Abidian M.R., Martin D.C. Multifunctional nanobiomaterials for neural interfaces. Advanced Functional Materials 2009, 19(4):573-585.
2. Abidian M.R., Kim D.H., Martin D.C. Conducting-polymer nanotubes for controlled drug release. Advanced Materials 2006, 18(4):405-409.
3. Abidian M.R., Ludwig K.A., Marzullo T.C., Martin D.C., Kipke D.R. Interfacing conducting polymer nanotubes with the central nervous system: chronic neural recording using poly(3,4-ethylenedioxythiophene) nanotubes. Advanced Materials 2009, 21(37):3764-3770.
4. Abidian M.R., Corey J.M., Kipke D.R., Martin D.C. Conducting-polymer nanotubes improve electrical properties, mechanical adhesion, neural attachment, and neurite outgrowth of neural electrodes. Small 2010, 6:421-429.
5. Akin T., Najafi K., Smoke R.H., Bradley R.M. A micromachined silicon sieve electrode for nerve regeneration applications. IEEE Transactions on Biomedical Engineering 1994, 41(4):305-313.
6. Anderson D.J., Najafi K., Tanghe S.J., Evans D.A., Levy K.L., Hetke J.F., Xue X., Zappia J.J., Wise K.D. Batch fabricated thin-film electrodes for stimulation of the central auditory system. IEEE Transactions on Biomedical Engineering 1989, 36(7):693-704.
7. Arcot Desai S., Rolston J.D., Guo L., Potter S.M. Improving impedance of implantable microwire multi-electrode arrays by ultrasonic electroplating of durable platinum black. Frontiers in Neuroengineering 2010, 3.
8. Attard G.S., Bartlett P.N., Coleman N.R.B., Elliott J.M., Owen J.R., Wang J.H. Mesoporous platinum films from lyotropic liquid crystalline phases. Science 1997, 278(5339):838-840.
9. Bai Q., Wise K.D., Anderson D.J. A high-yield microassembly structure for three-dimensional microelectrode arrays. IEEE Transactions on Biomedical Engineering 2000, 47(3):281-289.
10. Beebe X., Rose T.L. Charge injection limits of activated iridium oxide electrodes with 0.2ms pulses in bicarbonate buffered saline (neurological stimulation application). IEEE Transactions on Biomedical Engineering 1988, 35(6):494-495.
11. Berdondini L., Imfeld K., Maccione A., Tedesco M., Neukom S., Koudelka-Hep M., Martinoia S. Active pixel sensor array for high spatio-temporal resolution electrophysiological recordings from single cell to large scale neuronal networks. Lab on a Chip 2009, 9(18):2644-2651.
12. Blau A., Ziegler C., Heyer M., Endres F., Schwitzgebel G., Matthies T., Stieglitz T., Meyer J.U., Göpel W. Characterization and optimization of microelectrode arrays for in vivo nerve signal recording and stimulation. Biosensors and Bioelectronics 1997, 12(9-10):883-892.
13. Borkholder D.A., Bao J., Maluf N.I., Perl E.R., Kovacs G.T.A. Microelectrode arrays for stimulation of neural slice preparations. Journal of Neuroscience Methods 1997, 77(1):61-66.
14. Brummer S.B., Turner M.J. Electrical stimulation with pt electrodes: II - Estimation of maximum surface redox (theoretical non-gassing) limits. IEEE Transactions on BME - Biomedical Engineering 1977, 24(5):440-443.
15. Bucher V., Graf M., Stelzle M., Nisch W. Low-impedance thin-film polycrystalline silicon microelectrodes for extracellular stimulation and recording. Biosensors and Bioelectronics 1999, 14(7):639-649.
16. Charvet G., Rousseau L., Billoint O., Gharbi S., Rostaing J.-P., Joucla S., Trevisiol M., Bourgerette A., Chauvet P., Moulin C., Goy F., Mercier B., Colin M., Spirkovitch S., Fanet H., Meyrand P., Guillemaud R., Yvert B. BioMEA(TM): a versatile high-density 3D microelectrode array system using integrated electronics. Biosensors and Bioelectronics 2010, 25(8):1889-1896.
17. Chen C.-H., et al. Hydrophilic modification of neural microelectrode arrays based on multi-walled carbon nanotubes. Nanotechnology 2010, 21(48):485501.
18. Chen H., Guo L., Ferhan A.R., Kim D.-H. Multilayered polypyrrole-coated carbon nanotubes to improve functional stability and electrical properties of neural electrodes. The Journal of Physical Chemistry C 2011, 115(13):5492-5499.
19. Cogan S.F. Neural stimulation and recording electrodes. Annual Review of Biomedical Engineering 2008, 10(1):275-309.
20. Cogan S.F., Ehrlich J., Plante T.D., Smirnov A., Shire D.B., Gingerich M., Rizzo J.F. Sputtered iridium oxide films for neural stimulation electrodes. Journal of Biomedical Materials Research - Part B Applied Biomaterials 2009, 89(2):353-361.
21. Comstock D.J., Christensen S.T., Elam J.W., Pellin M.J., Hersam M.C. Synthesis of nanoporous activated iridium oxide films by anodized aluminum oxide templated atomic layer deposition. Electrochemistry Communications 2010, 90:1543-1546.
22. Csicsvari J., Henze D.A., Jamieson B., Harris K.D., Sirota A., Barthó P., Wise K.D., Buzsáki G. Massively parallel recording of unit and local field potentials with silicon-based electrodes. Journal of Neurophysiology 2003, 90(2):1314-1323.
23. Cui X., Martin D.C. Electrochemical deposition and characterization of poly(3,4-ethylenedioxythiophene) on neural microelectrode arrays. Sensors and Actuators B: Chemical 2003, 89(1-2):92-102.
24. Cui X., Martin D.C. Fuzzy gold electrodes for lowering impedance and improving adhesion with electrodeposited conducting polymer films. Sensors and Actuators A: Physical 2003, 103(3):384.
25. Cui X., Hetke J.F., Wiler J.A., Anderson D.J., Martin D.C. Electrochemical deposition and characterization of conducting polymer polypyrrole/PSS on multichannel neural probes. Sensors and Actuators A: Physical 2001, 93(1):8-18.
26. Cui X., Lee V.A., Raphael Y., Wiler J.A., Hetke J.F., Anderson D.J., Martin D.C. Surface modification of neural recording electrodes with conducting polymer/biomolecule blends. Journal of Biomedical Materials Research Part B 2001, 56:261-272.
27. Cui X., Wiler J., Dzaman M., Altschuler R.A., Martin D.C. In vivo studies of polypyrrole/peptide coated neural probes. Biomaterials 2003, 24(5):777-787.
28. Deligkaris K., Tadele T.S., Olthuis W., van den Berg A. Hydrogel-based devices for biomedical applications. Sensors and Actuators B: Chemical 2010, 147(2):765-774.
29. Egert U., Schlosshauer B., Fennrich S., Nisch W., Fejtl M., Knott T., Müller T., Hämmerle H. A novel organotypic long-term culture of the rat hippocampus on substrate-integrated multielectrode arrays. Brain Research Protocols 1998, 2(4):229-242.
30. Feltham A.M., Spiro M. Platinized platinum electrodes. Chemical Reviews 1971, 71(2):177-193.
31. Foos J.S., Erker S.M. Rate enhancement in modified polypyrrole electrodes. Journal of the Electrochemical Society 1986, 133(9):1983-1984.
32. Frey U., Egert U., Heer F., Hafizovic S., Hierlemann A. Microelectronic system for high-resolution mapping of extracellular electric fields applied to brain slices. Biosensors and Bioelectronics 2009, 24(7):2191-2198.
33. Fröhlich R., Rpzany A., Riedmüller J., Bolz A., Schaldach M. Electroactive coating of stimulating electrodes. Journal of Materials Science: Materials in Medicine 1996, 7(7):393-397.
34. Fung A.O., Tsiokos C., Paydar O., Chen L.H., Jin S., Wang Y., Judy J.W. Electrochemical properties and myocyte interaction of carbon nanotube microelectrodes. Nano Letters 2010, 10(11):4321-4327.
35. Gabay T., et al. Electro-chemical and biological properties of carbon nanotube based multi-electrode arrays. Nanotechnology 2007, 18(3):035201.
36. Gesteland R.C., Howland B., Lettvin J.Y., Pitts W.H. Comments on microelectrodes. Proceedings of the IRE 1959, 47(11):1856-1862.
37. Ghosh S., Inganäs O. Conducting polymer hydrogels as 3D electrodes: applications for supercapacitors. Advanced Materials 1999, 11(14):1214-1218.
38. Green R., Williams C., Lovell N., Poole-Warren L. Novel neural interface for implant electrodes: improving electroactivity of polypyrrole through MWNT incorporation. Journal of Materials Science: Materials in Medicine 2008, 19(4):1625-1629.
39. Green R.A., Lovell N.H., Wallace G.G., Poole-Warren L.A. Conducting polymers for neural interfaces: challenges in developing an effective long-term implant. Biomaterials 2008, 29(24-25):3393-3399.
40. Gross G.W., Williams A.N., Lucas J.H. Recording of spontaneous activity with photoetched microelectrode surfaces from mouse spinal neurons in culture. Journal of Neuroscience Methods 1982, 5(1-2):13-22.
41. Guyton D.L., Hambrecht F.T. Capacitor electrode stimulates nerve or muscle without oxidation reduction reactions. Science 1973, 181(4094):74-76.
42. Guyton D., Terry Hambrecht F. Theory and design of capacitor electrodes for chronic stimulation. Medical and Biological Engineering and Computing 1974, 12(5):613-620.
43. Haberler C., Alesch F., Mazal P.R., Pilz P., Jellinger K., Pinter M.M., Hainfellner J.A., Budka H. No Tissue Damage by Chronic Deep Brain Stimulation in Parkinson's Disease. Annals of Neurology 2000, 48:372-376.
44. Hämmerle H., Kobuch K., Kohler K., Nisch W., Sachs H., Stelzle M. Biostability of micro-photodiode arrays for subretinal implantation. Biomaterials 2002, 23(3):797-804.
45. Heck D. Investigating dynamic aspects of brain function in slice preparations: spatiotemporal stimulus patterns generated with an easy-to-build multi-electrode array. Journal of Neuroscience Methods 1995, 58(1-2):81-87.
46. Heim, M., Urbanova, V., Bouffier, L., Mazzocco, C., Rousseau, L., Vytras, K., Bartlett, P.N., Kuhn, A., Yvert, B., submitted for publication. Mesoporous microelectrode arrays (MEAs) for low noise recording of neural networks.
47. Heuschkel M.O., Fejtl M., Raggenbass M., Bertrand D., Renaud P. A three-dimensional multi-electrode array for multi-site stimulation and recording in acute brain slices. Journal of Neuroscience Methods 2002, 114(2):135-148.
48. Hu J., Abdelsalam M., Bartlett P., Cole R., Sugawara Y., Baumberg J., Mahajan S., Denuault G. Electrodeposition of highly ordered macroporous iridium oxide through self-assembled colloidal templates. Journal of Materials Chemistry 2009, 19(23):3855-3858.
49. Hughes M., Chen G.Z., Shaffer M.S.P., Fray D.J., Windle A.H. Electrochemical capacitance of a nanoporous composite of carbon nanotubes and polypyrrole. Chemistry of Materials 2002, 14(4):1610-1613.
50. Hughes M., Shaffer M.S.P., Renouf A.C., Singh C., Chen G.Z., Fray D.J., Windle A.H. Electrochemical capacitance of nanocomposite films formed by coating aligned arrays of carbon nanotubes with polypyrrole. Advanced Materials 2002, 14(5):382-385.
51. Hutzler M., Lambacher A., Eversmann B., Jenkner M., Thewes R., Fromherz P. High-resolution multitransistor array recording of electrical field potentials in cultured brain slices. Journal of Neurophysiology 2006, 96(3):1638-1645.
52. Jackson A., Mavoori J., Fetz E.E. Long-term motor cortex plasticity induced by an electronic neural implant. Nature 2006, 444(7115):56-60.
53. Jan E., Hendricks J.L., Husaini V., Richardson-Burns S.M., Sereno A., Martin D.C., Kotov N.A. Layered carbon nanotube-polyelectrolyte electrodes outperform traditional neural interface materials. Nano Letters 2009, 9(12):4012-4018.
54. Janders, M., Egert, U., Stelzle, M., Nisch, W., 1996. Novel thin film titanium nitride micro-electrodes with excellent charge transfer capability for cell stimulation and sensing applications. In: Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE, vol. 241. pp. 245-247.
55. Johnson J.B. Thermal agitation of electricity in conductors. Physical Review 1928, 32(1):97.
56. Jun S., Hynd M., Smith K., Song J., Turner J., Shain W., Kim S. Electrical stimulation-induced cell clustering in cultured neural networks. Medical and Biological Engineering and Computing 2007, 45(11):1015-1021.
57. Kang K.S., Shay J.L. Blue sputtered iridium oxide films (Blue SIROF's). Journal of the Electrochemical Society 1983, 130(4):766-769.
58. Kang G., Borgens R.B., Cho Y. Well-ordered porous conductive polypyrrole as a new platform for neural interfaces. Langmuir 2011, 27(10):6179-6184.
59. Keefer E.W., Botterman B.R., Romero M.I., Rossi A.F., Gross G.W. Carbon nanotube coating improves neuronal recordings. Nature Nanotechnology 2008, 3(7):434-439.
60. Kim D.-H., Abidian M., Martin D.C. Conducting polymers grown in hydrogel scaffolds coated on neural prosthetic devices. Journal of Biomedical Materials Research Part A 2004, 71A:577-585.
61. Kim D.H., Richardson-Burns S.M., Hendricks J.L., Sequera C., Martin D.C. Effect of Immobilized Nerve Growth Factor on Conductive Polymers: Electrical Properties and Cellular Response 2007, Wiley, pp. 79-86.
62. Kim D.H., Wiler J.A., Anderson D.J., Kipke D.R., Martin D.C. Conducting polymers on hydrogel-coated neural electrode provide sensitive neural recordings in auditory cortex. Acta Biomaterialia 2010, 6(1):57-62.
63. Kotov N.A., Winter J.O., Clements I.P., Jan E., Timko B.P., Campidelli S., Pathak S., Mazzatenta A., Lieber C.M., Prato M., Bellamkonda R.V., Silva G.A., Kam N.W.S., Patolsky F., Ballerini L. Nanomaterials for neural interfaces. Advanced Materials 2009, 21:3970-4004.
64. Kotwal A., Schmidt C.E. Electrical stimulation alters protein adsorption and nerve cell interactions with electrically conducting biomaterials. Biomaterials 2001, 22(10):1055-1064.
65. Kovacs G.T.A. Enabling Technologies for Cultured Neural Networks 1994, 121. Academic Press, London, UK. D.A. Stenger, T.M. McKenna (Eds.).
66. Kovacs G.T.A., Storment C.W., Halks-Miller M., Belczynski C.R., Santina C.C.D., Lewis E.R., Maluf N.I. Silicon-substrate microelectrode arrays for parallel recording of neural activity in peripheral and cranial nerves. IEEE Transactions on Biomedical Engineering 1994, 41(6):567-577.
67. Kuncel A.M., Grill W.M. Selection of stimulus parameters for deep brain stimulation. Clinical Neurophysiology 2004, 115(11):2431-2441.
68. Lehmann V., Foll H. Formation mechanism and properties of electrochemically etched trenches in n-type silicon. Journal of the Electrochemical Society 1990, 137(2):653-659.
69. Li P., Lim X., Zhu Y., Yu T., Ong C.-K., Shen Z., Wee A.T.-S., Sow C.-H. Tailoring wettability change on aligned and patterned carbon nanotube films for selective assembly. The Journal of Physical Chemistry B 2007, 111(7):1672-1678.
70. Lovat V., Pantarotto D., Lagostena L., Cacciari B., Grandolfo M., Righi M., Spalluto G., Prato M., Ballerini L. Carbon nanotube substrates boost neuronal electrical signaling. Nano Letters 2005, 5(6):1107-1110.
71. Lu Y., Wang T., Cai Z., Cao Y., Yang H., Duan Y.Y. Anodically electrodeposited iridium oxide films microelectrodes for neural microstimulation and recording. Sensors and Actuators B: Chemical 2009, 137(1):334-339.
72. Lu Y., Li T., Zhao X., Li M., Cao Y., Yang H., Duan Y.Y. Electrodeposited polypyrrole/carbon nanotubes composite films electrodes for neural interfaces. Biomaterials 2010, 31(19):5169-5181.
73. Ludwig K.A., Uram J.D., Yang J., Martin D.C., Kipke D.R. Chronic neural recordings using silicon microelectrode arrays electrochemically deposited with a poly(3,4-ethylenedioxythiophene) (PEDOT) film. Journal of Neural Engineering 2006, 3(1):59-70.
74. Ludwig K.A., et al. Poly(3,4-ethylenedioxythiophene) (PEDOT) polymer coatings facilitate smaller neural recording electrodes. Journal of Neural Engineering 2011, 8(1):014001.
75. Mailley S.C., Hyland M., Mailley P., McLaughlin J.M., McAdams E.T. Electrochemical and structural characterizations of electrodeposited iridium oxide thin-film electrodes applied to neurostimulating electrical signal. Materials Science and Engineering: C 2002, 21(1-2):167-175.
76. Marrese C.A. Preparation of strongly adherent platinum black coatings. Analytical Chemistry 1987, 59(1):217-218.
77. Maynard E.M., Nordhausen C.T., Normann R.A. The Utah intracortical electrode array: a recording structure for potential brain-computer interfaces. Electroencephalography and Clinical Neurophysiology 1997, 102(3):228-239.
78. Mazzatenta A., Giugliano M., Campidelli S., Gambazzi L., Businaro L., Markram H., Prato M., Ballerini L. Interfacing neurons with carbon nanotubes: electrical signal transfer and synaptic stimulation in cultured brain circuits. The Journal of Neuroscience 2007, 27(26):6931-6936.
79. McCreery D.B., Agnew W.F., Yuen T.G.H., Bullara L. Charge density and charge per phase as cofactors in neural injury induced by electrical stimulation. IEEE Transactions on Biomedical Engineering 1990, 37(10):996-1001.
80. Merrill D.R., Bikson M., Jefferys J.G.R. Electrical stimulation of excitable tissue: design of efficacious and safe protocols. Journal of Neuroscience Methods 2005, 141(2):171-198.
81. Meyer R.D., Cogan S.F., Nguyen T.H., Rauh R.D. Electrodeposited iridium oxide for neural stimulation and recording electrodes. IEEE Transactions on Neural Systems and Rehabilitation Engineering 2001, 9(1):2-11.
82. Negi S., Bhandari R., Rieth L., Solzbacher F. Effect of sputtering pressure on pulsed-DC sputtered iridium oxide films. Sensors and Actuators B: Chemical 2009, 137(1):370-378.
83. Negi S., Bhandari R., Rieth L., Van Wagenen R., Solzbacher F. Neural electrode degradation from continuous electrical stimulation: comparison of sputtered and activated iridium oxide. Journal of Neuroscience Methods 2010, 186(1):8-17.
84. Nguyen-Vu T.D.B., Chen H., Cassell A.M., Andrews R., Meyyappan M., Li J. Vertically aligned carbon nanofiber arrays: an advance toward electrical-neural interfaces. Small 2006, 2(1):89-94.
85. Nguyen-Vu T.D.B., Chen H., Cassell A.M., Andrews R.J., Meyyappan M., Li J. Vertically aligned carbon nanofiber architecture as a multifunctional 3-D neural electrical interface. IEEE Transactions on Biomedical Engineering 2007, 54(6):1121-1128.
86. Norlin A., Pan J., Leygraf C. Investigation of electrochemical behavior of stimulation/sensing materials for pacemaker electrode applications. Journal of the Electrochemical Society 2005, 152(2):J7-J15.
87. Nyberg T., Inganäs O., Jerregård H. Polymer hydrogel microelectrodes for neural communication. Biomedical Microdevices 2002, 4(1):43-52.
88. Nyberg T., Shimada A., Torimitsu K. Ion conducting polymer microelectrodes for interfacing with neural networks. Journal of Neuroscience Methods 2007, 160(1):16-25.
89. Park S., Song Y.J., Boo H., Chung T.D. Nanoporous Pt microelectrode for neural stimulation and recording: in vitro characterization. The Journal of Physical Chemistry C 2010, 114(19):8721-8726.
90. Regehr W.G., Pine J., Rutledge D.B. A long-term in vitro silicon-based microelectrode-neuron connection. IEEE Transactions on Biomedical Engineering 1988, 35(12):1023-1032.
91. Richardson-Burns S.M., Hendricks J.L., Foster B., Povlich L.K., Kim D.-H., Martin D.C. Polymerization of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) around living neural cells. Biomaterials 2007, 28(8):1539-1552.
92. Richardson-Burns S.M., Hendricks J.L., Martin D.C. Electrochemical polymerization of conducting polymers in living neural tissue. Journal of Neural Engineering 2007, 4(2):L6-L13.
93. Robblee L.S., Rose T.L. Electrochemical guidelines for selection of protocols and electrode materials for neural stimulation. Neural Protheses: Fundamental Studies 1990, 25-66. Prentice Hall, Englewood Cliffs, New Jersey. W.F. Agnew, D.B. McCreery (Eds.).
94. Robinson D.A. The electrical properties of metal microelectrodes. Proceedings of the IEEE 1968, 56(6):1065-1071.
95. Rose T.L., Kelliher E.M., Robblee L.S. Assessment of capacitor electrodes for intracortical neural stimulation. Journal of Neuroscience Methods 1985, 12(3):181-193.
96. Schmidt C.E., Shastri V.R., Vacanti J.P., Langer R. Stimulation of neurite outgrowth using an electrically conducting polymer. Proceedings of the National Academy of Sciences 1997, 94(17):8948-8953.
97. Seung-Joon P., et al. Roughened polysilicon for low impedance microelectrodes in neural probes. Journal of Micromechanics and Microengineering 2003, 13(3):373.
98. Sirivisoot S., Pareta R., Webster J.T. Electrically controlled drug release from nanostructured polypyrrole coated on titanium. Nanotechnology 2011, 22(8):085101.
99. Slavcheva E., Vitushinsky R., Mokwa W., Schnakenberg U. Sputtered iridium oxide films as charge injection material for functional electrostimulation. Journal of the Electrochemical Society 2004, 151(7):E226-E237.
100. Stauffer W.R., Cui X.T. Polypyrrole doped with 2 peptide sequences from laminin. Biomaterials 2006, 27(11):2405-2413.
101. Su H.-C., Lin C.-M., Yen S.-J., Chen Y.-C., Chen C.-H., Yeh S.-R., Fang W., Chen H., Yao D.-J., Chang Y.-C., Yew T.-R. A cone-shaped 3D carbon nanotube probe for neural recording. Biosensors and Bioelectronics 2010, 26(1):220-227.
102. Szamocki R., Velichko A., Mücklich F., Reculusa S., Ravaine S., Neugebauer S., Schuhmann W., Hempelmann R., Kuhn A. Improved enzyme immobilization for enhanced bioelectrocatalytic activity of porous electrodes. Electrochemistry Communications 2007, 9(8):2121-2127.
103. Thomas C.A., Springer P.A., Loeb G.E., Berwald-Netter Y., Okun L.M. A miniature microelectrode array to monitor the bioelectric activity of cultured cells. Experimental Cell Research 1972, 74(1):61-66.
104. Urbanová V., Li Y., Vytras K., Yvert B., Kuhn A. Macroporous microelectrode arrays for measurements with reduced noise. Journal of Electroanalytical Chemistry 2011, 656:91-95.
105. Van Ooyen A., Topalov G., Ganske G., Mokwa W., Schnakenberg U. Iridium oxide deposited by pulsed dc-sputtering for stimulation electrodes. Journal of Micromechanics and Microengineering 2009, 19(7).
106. Voge C.M., Stegemann J.P. Carbon nanotubes in neural interfacing applications. Journal of Neural Engineering 2011, 8(1):011001.
107. Wadhwa R., Lagenaur C.F., Cui X.T. Electrochemically controlled release of dexamethasone from conducting polymer polypyrrole coated electrode. Journal of Controlled Release 2006, 110(3):531-541.
108. Walter P., Heimann K. Evoked cortical potentials after electrical stimulation of the inner retina in rabbits. Graefe's Archive for Clinical and Experimental Ophthalmology 2000, 238(4):315-318.
109. Wang K., Fishman H.A., Dai H., Harris J.S. Neural stimulation with a carbon nanotube microelectrode array. Nano Letters 2006, 6(9):2043-2048.
110. Weiland J.D., Anderson D.J., Humayun M.S. In vitro electrical properties for iridium oxide versus titanium nitride stimulating electrodes. IEEE Transactions on Biomedical Engineering 2002, 49(12):1574-1579.
111. Wessling B., Mokwa W., Schnakenberg U. RF-sputtering of iridium oxide to be used as stimulation material in functional medical implants. Journal of Micromechanics and Microengineering 2006, 16(6):S142-S148.
112. Wessling B., Besmehn A., Mokwa W., Schnakenberg U. Reactively sputtered iridium oxide. Journal of the Electrochemical Society 2007, 154(5):F83-F89.
113. Wessling B., Mokwa W., Schnakenberg U. Sputtered IR films evaluated for electrochemical performance I. Experimental results. Journal of the Electrochemical Society 2008, 155(5):F61-F65.
114. Yamato H., Ohwa M., Wernet W. Stability of polypyrrole and poly(3,4-ethylenedioxythiophene) for biosensor application. Journal of Electroanalytical Chemistry 1995, 397(1-2):163-170.
115. Yang J., Martin D.C. Microporous conducting polymers on neural microelectrode arrays: II. Physical characterization. Sensors and Actuators A: Physical 2004, 113(2):204-211.
116. Yang J., Kim D.H., Hendricks J.L., Leach M., Northey R., Martin D.C. Ordered surfactant-templated poly(3,4-ethylenedioxythiophene) (PEDOT) conducting polymer on microfabricated neural probes. Acta Biomaterialia 2005, 1(1):125-136.
117. Yu Z., McKnight T.E., Ericson M.N., Melechko A.V., Simpson M.L., Morrison B. Vertically aligned carbon nanofiber arrays record electrophysiological signals from hippocampal slices. Nano Letters 2007, 7(8):2188-2195.
118. Zhang X., Prasad S., Niyogi S., Morgan A., Ozkan M., Ozkan C.S. Guided neurite growth on patterned carbon nanotubes. Sensors and Actuators B: Chemical 2005, 106(2):843-850.