Effect of JBP485 on obstructive jaundice is related to regulation of renal Oat1, Oat3 and Mrp2 expression in ANIT-treated rats

Peptides

Volumn 36, Issue 1, 2012, Pages 78-85

  Liu, Tao ^a   Guo, Xinjin ^a   Meng, Qiang ^a   Wang, Changyuan ^a   Liu, Qi ^a   Sun, Huijun ^a   Ma, Xiaochi ^a   Kaku, Taiichi ^b   Liu, Kexin ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b Japan Bioproducts Industry Co Ltd   (Japan)

Author keywords

Biliary obstruction; JBP485; Mrp2; Oat1; Oat3; Pharmacokinetics

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; JBP 485; LIVER PROTECTIVE AGENT; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 3; SILYMARIN; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG STRUCTURE; DRUG UPTAKE; DRUG URINE LEVEL; HISTOCHEMISTRY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LIVER PROTECTION; MALE; MASS SPECTROMETRY; NONHUMAN; OBSTRUCTIVE JAUNDICE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION; WESTERN BLOTTING;

1-NAPHTHYLISOTHIOCYANATE; ALANINE TRANSAMINASE; ANIMALS; AREA UNDER CURVE; ASPARTATE AMINOTRANSFERASES; ATP-BINDING CASSETTE TRANSPORTERS; BILIRUBIN; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; JAUNDICE, OBSTRUCTIVE; KIDNEY; LIVER; MALE; ORGANIC ANION TRANSPORT PROTEIN 1; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; PEPTIDES, CYCLIC; RATS; RATS, WISTAR; TRANSCRIPTION, GENETIC;

RATTUS;

EID: 84862153113     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.04.003     Document Type: Article

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