A multidisciplinary approach for the analysis of an adulterated dietary supplement where the active pharmaceutical ingredient was embedded in the capsule shell

Journal of Pharmaceutical and Biomedical Analysis

Volumn 67-68, Issue , 2012, Pages 22-27

  Lanzarotta, Adam ^a   Crowe, John B ^a   Witkowski, Mark ^a   Gamble, Bryan M ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Adulteration; Dietary supplement; Infrared imaging; LC MS; Optical microscopy; Raman spectroscopy

Indexed keywords

ACTIVE PHARMACEUTICAL AGENT; CARBON DIOXIDE; CHEMICALS AND DRUGS; GELATIN; PHOSPHODIESTERASE V; TADALAFIL; UNCLASSIFIED DRUG;

ARTICLE; DIET SUPPLEMENTATION; DRUG CAPSULE; DRUG DETERMINATION; DRUG MANUFACTURE; ENCAPSULATION; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; MICROSCOPY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAMAN SPECTROMETRY; THICKNESS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIETARY SUPPLEMENTS; PHARMACEUTICAL PREPARATIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTRUM ANALYSIS, RAMAN; TANDEM MASS SPECTROMETRY;

EID: 84862141500     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.04.023     Document Type: Article

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