Apoptotic tumor cells induce IL-27 release from human DCs to activate Treg cells that express CD69 and attenuate cytotoxicity

European Journal of Immunology

Volumn 42, Issue 6, 2012, Pages 1585-1598

  Sekar, Divya ^a   Hahn, Christina ^a   Brüne, Bernhard ^a   Roberts, Edward ^b   Weigert, Andreas ^a  

^a GOETHE UNIVERSITY   (Germany)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Cancer; Cell death; Dendritic cells; Regulatory T cells; Tumor immunology

Indexed keywords

5' NUCLEOTIDASE; B7 ANTIGEN; CD3 ANTIGEN; CD39 ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 27; INTERLEUKIN 4; INTERLEUKIN 6; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CANCER CELL; CELL ACTIVATION; CELL CULTURE; CELL INTERACTION; CELL ISOLATION; CELL KILLING; CELL POPULATION; CELL TRANSFER; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TUMOR CELL;

ADENOSINE; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; APOPTOSIS; APYRASE; CELL LINE, TUMOR; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; INTERLEUKINS; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; NEOPLASMS; RECEPTORS, LYSOSPHINGOLIPID; T-LYMPHOCYTES, REGULATORY;

EID: 84862132122     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201142093     Document Type: Article

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