Vis-à-Vis in the NKC: Genetically linked Natural killer cell receptor/ligand pairs in the Natural killer gene complex (NKC)

Journal of Innate Immunity

Volumn 3, Issue 3, 2011, Pages 227-235

  Vogler, Isabel ^a   Steinle, Alexander ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

C type lectin like receptors; Cytotoxicity; Immune response; Natural killer cells; Natural killer gene complex; Vertebrates

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CD94 ANTIGEN; DECTIN 1; GAMMA INTERFERON; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2A; NATURAL KILLER CELL RECEPTOR NKG2D; NK P6 PROTEIN; NK P80 ANTIGEN; UNCLASSIFIED DRUG;

B LYMPHOCYTE; BONE MARROW CELL; CELL COMMUNICATION; CELL STRESS; CELL SURFACE; CHROMOSOME 19; GAMMA DELTA T LYMPHOCYTE; GENE; GENE CLUSTER; HUMAN; KERATINOCYTE; NATURAL KILLER CELL; NATURAL KILLER GENE COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW;

ANIMALS; GENE REGULATORY NETWORKS; GENETIC LINKAGE; HUMANS; IMMUNITY, INNATE; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LIGANDS; MEMBRANE GLYCOPROTEINS; MICE; ORGAN SPECIFICITY; RECEPTOR CROSS-TALK; RECEPTORS, NATURAL KILLER CELL;

EID: 79955109235     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000324112     Document Type: Review

References (55)

1. Raulet DH, Vance RE: Self-tolerance of natural killer cells. Nat Rev Immunol 2006; 6: 520-531. (Pubitemid 43980524)
2. Vivier E, Tomasello E, Baratin M, Walzer T, Ugolini S: Functions of natural killer cells. Nat Immunol 2008; 9: 503-510. (Pubitemid 351560519)
3. Yokoyama WM, Plougastel BF: Immune functions encoded by the natural killer gene complex. Nat Rev Immunol 2003; 3: 304-316. (Pubitemid 37328683)
4. Di Santo JP: Natural killer cells: diversity in search of a niche. Nat Immunol 2008; 9: 473-475. (Pubitemid 351560514)
5. Bryceson YT, Long EO: Line of attack: NK cell specificity and integration of signals. Curr Opin Immunol 2008; 20: 344-352.
6. Kelley J, Walter L, Trowsdale J: Comparative genomics of natural killer cell receptor gene clusters. PLoS Genet 2005; 1: 129-139.
7. Yokoyama WM, Seaman WE: The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Annu Rev Immunol 1993; 11: 613-635. (Pubitemid 23115019)
8. Zelensky AN, Gready JE: The C-type lectinlike domain superfamily. FEBS J 2005; 272: 6179-6217.
9. Hao L, Klein J, Nei M: Heterogeneous but conserved natural killer receptor gene complexes in four major orders of mammals. Proc Natl Acad Sci USA 2006; 103: 3192-3197. (Pubitemid 43346446)
10. Reid DM, Gow NA, Brown GD: Pattern recognition: recent insights from Dectin-1. Curr Opin Immunol 2009; 21: 30-37.
11. Llera AS, Viedma F, Sanchez-Madrid F, Tormo J: Crystal structure of the C-type lectinlike domain from the human hematopoietic cell receptor CD69. J Biol Chem 2001; 276: 7312-7319.
12. Natarajan K, Sawicki MW, Margulies DH, Mariuzza RA: Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells. Biochemistry 2000; 39: 14779-14786.
13. Spreu J, Kienle EC, Schrage B, Steinle A: CLEC2A: a novel, alternatively spliced and skin-associated member of the NKC-encoded AICL-CD69-LLT1 family. Immunogenetics 2007; 59: 903-912. (Pubitemid 50005854)
14. Iizuka K, Naidenko OV, Plougastel BF, Fremont DH, Yokoyama WM: Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors. Nat Immunol 2003; 4: 801-807. (Pubitemid 36986765)
15. Glimcher L, Shen FW, Cantor H: Identification of a cell-surface antigen selectively expressed on the natural killer cell. J Exp Med 1977; 145: 1-9. (Pubitemid 8010087)
16. Chambers WH, Vujanovic NL, DeLeo AB, Olszowy MW, Herberman RB, Hiserodt JC: Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells. J Exp Med 1989; 169: 1373-1389. (Pubitemid 19104969)
17. Carlyle JR, Mesci A, Ljutic B, Belanger S, Tai LH, Rousselle E, Troke AD, Proteau MF, Makrigiannis AP: Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells. J Immunol 2006; 176: 7511-7524. (Pubitemid 43849055)
18. Arase N, Arase H, Park SY, Ohno H, Ra C, Saito T: Association with FcRgamma is essential for activation signal through NKR-P1 (CD161) in natural killer (NK) cells and NK1.1+ T cells. J Exp Med 1997; 186: 1957-1963. (Pubitemid 28013679)
19. Carlyle JR, Mesci A, Fine JH, Chen P, Belanger S, Tai LH, Makrigiannis AP: Evolution of the Ly49 and Nkrp1 recognition systems. Semin Immunol 2008; 20: 321-330.
20. Aust JG, Gays F, Mickiewicz KM, Buchanan E, Brooks CG: The expression and function of the NKRP1 receptor family in C57BL/6 mice. J Immunol 2009; 183: 106-116.
21. Tian W, Nunez R, Cheng S, Ding Y, Tumang J, Lyddane C, Roman C, Liou HC: C-type lectin OCILRP2/Clr-g and its ligand NKRP1f costimulate T cell proliferation and IL-2 production. Cell Immunol 2005; 234: 39-53. (Pubitemid 41140390)
22. Ljutic B, Carlyle JR, Filipp D, Nakagawa R, Julius M, Zuniga-Pflucker JC: Functional requirements for signaling through the stimulatory and inhibitory mouse NKR-P1 (CD161) NK cell receptors. J Immunol 2005; 174: 4789-4796.
23. Carlyle JR, Jamieson AM, Gasser S, Clingan CS, Arase H, Raulet DH: Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. Proc Natl Acad Sci USA 2004; 101: 3527-3532. (Pubitemid 38338229)
24. Plougastel B, Dubbelde C, Yokoyama WM: Cloning of Clr, a new family of lectin-like genes localized between mouse Nkrp1a and Cd69. Immunogenetics 2001; 53: 209-214. (Pubitemid 32436939)
25. Kartsogiannis V, Sims NA, Quinn JM, Ly C, Cipetic M, Poulton IJ, Walker EC, Saleh H, McGregor NE, Wallace ME, Smyth MJ, Martin TJ, et al: Osteoclast inhibitory lectin, an immune cell product that is required for normal bone physiology in vivo. J Biol Chem 2008; 283: 30850-30860.
26. Fine JH, Chen P, Mesci A, Allan DS, Gasser S, Raulet DH, Carlyle JR: Chemotherapy-induced genotoxic stress promotes sensitivity to natural killer cell cytotoxicity by enabling missing-self recognition. Cancer Res 2010; 70: 7102-7113.
27. Voigt S, Mesci A, Ettinger J, Fine JH, Chen P, Chou W, Carlyle JR: Cytomegalovirus evasion of innate immunity by subversion of the NKR-P1B:Clr-b missing-self axis. Immunity 2007; 26: 617-627. (Pubitemid 46756346)
28. Flornes LM, Nylenna O, Saether PC, Daws MR, Dissen E, Fossum S: The complete inventory of receptors encoded by the rat natural killer cell gene complex. Immunogenetics 2010; 62: 521-530.
29. Kveberg L, Dai KZ, Westgaard IH, Daws MR, Fossum S, Naper C, Vaage JT: Two major groups of rat NKR-P1 receptors can be distinguished based on chromosomal localization, phylogenetic analysis and Clr ligand binding. Eur J Immunol 2009; 39: 541-551.
30. Lanier LL, Chang C, Phillips JH: Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J Immunol 1994; 153: 2417-2428. (Pubitemid 24278110)
31. Iiai T, Watanabe H, Suda T, Okamoto H, Abo T, Hatakeyama K: CD161+ T (NT) cells exist predominantly in human intestinal epithelium as well as in liver. Clin Exp Immunol 2002; 129: 92-98.
32. Maggi L, Santarlasci V, Capone M, Peired A, Frosali F, Crome SQ, Querci V, Fambrini M, Liotta F, Levings MK, Maggi E, Cosmi L, et al: CD161 is a marker of all human IL- 17-producing T-cell subsets and is induced by RORC. Eur J Immunol 2010; 40: 2174-2181.
33. Rosen DB, Cao W, Avery DT, Tangye SG, Liu YJ, Houchins JP, Lanier LL: Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells. J Immunol 2008; 180: 6508-6517.
34. Aldemir H, Prod'homme V, Dumaurier MJ, Retiere C, Poupon G, Cazareth J, Bihl F, Braud VM: Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptor. J Immunol 2005; 175: 7791-7795. (Pubitemid 41798337)
35. Rosen DB, Bettadapura J, Alsharifi M, Mathew PA, Warren HS, Lanier LL: Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor. J Immunol 2005; 175: 7796-7799. (Pubitemid 41798338)
36. Pozo D, Vales-Gomez M, Mavaddat N, Williamson SC, Chisholm SE, Reyburn H: CD161 (human NKR-P1A) signaling in NK cells involves the activation of acid sphingomyelinase. J Immunol 2006; 176: 2397-2406. (Pubitemid 43201689)
37. Mathew PA, Chuang SS, Vaidya SV, Kumaresan PR, Boles KS, Pham HT: The LLT1 receptor induces IFN-gamma production by human natural killer cells. Mol Immunol 2004; 40: 1157-1163. (Pubitemid 38210268)
38. Roth P, Mittelbronn M, Wick W, Meyermann R, Tatagiba M, Weller M: Malignant glioma cells counteract antitumor immune responses through expression of lectin-like transcript-1. Cancer Res 2007; 67: 3540-3544. (Pubitemid 46762134)
39. Poggi A, Zocchi MR, Costa P, Ferrero E, Borsellino G, Placido R, Galgani S, Salvetti M, Gasperini C, Ristori G, Brosnan CF, Battistini L: IL-12-mediated NKRP1A up-regulation and consequent enhancement of endothelial transmigration of V delta 2+ TCR gamma delta+ T lymphocytes from healthy donors and multiple sclerosis patients. J Immunol 1999; 162: 4349-4354. (Pubitemid 29314828)
40. Roda-Navarro P, Arce I, Renedo M, Montgomery K, Kucherlapati R, Fernandez-Ruiz E: Human KLRF1, a novel member of the killer cell lectin-like receptor gene family: molecular characterization, genomic structure, physical mapping to the NK gene complex and expression analysis. Eur J Immunol 2000; 30: 568-576. (Pubitemid 30098850)
41. Vitale M, Falco M, Castriconi R, Parolini S, Zambello R, Semenzato G, Biassoni R, Bottino C, Moretta L, Moretta A: Identification of NKp80, a novel triggering molecule expressed by human NK cells. Eur J Immunol 2001; 31: 233-242.
42. Welte S, Kuttruff S, Waldhauer I, Steinle A: Mutual activation of natural killer cells and monocytes mediated by NKp80-AICL interaction. Nat Immunol 2006; 7: 1334-1342. (Pubitemid 46111255)
43. Kuttruff S, Koch S, Kelp A, Pawelec G, Rammensee HG, Steinle A: NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood 2008; 113: 358-369.
44. Biassoni R, Fogli M, Cantoni C, Costa P, Conte R, Koopman G, Cafaro A, Ensoli B, Moretta A, Moretta L, De Maria A: Molecular and functional characterization of NKG2D, NKp80, and NKG2C triggering NK cell receptors in rhesus and cynomolgus macaques: monitoring of NK cell function during simian HIV infection. J Immunol 2005; 174: 5695-5705. (Pubitemid 40593212)
45. Mavilio D, Benjamin J, Kim D, Lombardo G, Daucher M, Kinter A, Nies-Kraske E, Marcenaro E, Moretta A, Fauci AS: Identification of NKG2A and NKp80 as specific natural killer cell markers in rhesus and pigtailed monkeys. Blood 2005; 106: 1718-1725. (Pubitemid 41208586)
46. Spreu J, Kuttruff S, Stejfova V, Dennehy KM, Schittek B, Steinle A: Interaction of C-type lectin-like receptors NKp65 and KACL facilitates dedicated immune recognition of human keratinocytes. Proc Natl Acad Sci USA 2010; 107: 5100-5105.
47. Fuller GL, Williams JA, Tomlinson MG, Eble JA, Hanna SL, Pohlmann S, Suzuki-Inoue K, Ozaki Y, Watson SP, Pearce AC: The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade. J Biol Chem 2007; 282: 12397-12409. (Pubitemid 47100620)
48. Dennehy KM, Klimosch SN, Steinle A: Cutting edge: NKp80 uses an atypical hemi- ITAM to trigger NK cytotoxicity. J Immunol 2011; 186: 657-661.
49. Hamann J, Montgomery KT, Lau S, Kucherlapati R, van Lier RA: AICL: a new activation- induced antigen encoded by the human NK gene complex. Immunogenetics 1997; 45: 295-300. (Pubitemid 27101733)
50. Pende D, Rivera P, Marcenaro S, Chang CC, Biassoni R, Conte R, Kubin M, Cosman D, Ferrone S, Moretta L, Moretta A: Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity. Cancer Res 2002; 62: 6178-6186. (Pubitemid 35244469)
51. Akatsuka A, Ito M, Yamauchi C, Ochiai A, Yamamoto K, Matsumoto N: Tumor cells of non-hematopoietic and hematopoietic origins express activation-induced C-type lectin, the ligand for killer cell lectin-like receptor F1. Int Immunol 2010; 22: 783-790.
52. Kloss M, Decker P, Baltz KM, Baessler T, Jung G, Rammensee HG, Steinle A, Krusch M, Salih HR: Interaction of monocytes with NK cells upon Toll-like receptor-induced expression of the NKG2D ligand MICA. J Immunol 2008; 181: 6711-6719.
53. Thomas M, Boname JM, Field S, Nejentsev S, Salio M, Cerundolo V, Wills M, Lehner PJ: Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity. Proc Natl Acad Sci USA 2008; 105: 1656-1661. (Pubitemid 351346570)
54. Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Engle XA, Rigby WF, Pioli PA, Guyre PM, Conejo-Garcia JR: PILAR is a novel modulator of human T-cell expansion. Blood 2008; 112: 1259-1268.
55. Germain C, Bihl F, Zahn S, Poupon G, Dumaurier MJ, Rampanarivo HH, Berg PS, Spee P, Braud VM: Characterization of alternatively spliced transcript variants of CLEC2D gene. J Biol Chem 2010; 85: 36207-36215.