Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains

Physiological Genomics

Volumn 44, Issue 9, 2012, Pages 487-494

  Houštěk, Josef ^a   Hejzlarová, Kateřina ^a   Vrbacký, Marek ^a   Drahota, Zdeněk ^a   Landa, Vladimír ^a   Zídek, Václav ^a   Mlejnek, Petr ^a   Šimáková, Miroslava ^a   Šilhavý, Jan ^a   Mikšík, Ivan ^a   Kazdová, Ludmila ^b   Oliyarnyk, Olena ^b   Kurtz, Theodore ^c   Pravenec, Michal ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Conplastic; Insulin resistance; Mitochondria; Spontaneously hypertensive rat

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; GLYCOGEN; MITOCHONDRIAL DNA;

AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; DNA SEQUENCE; GENE DOSAGE; GENETIC VARIABILITY; GLUCOSE METABOLISM; GLUCOSE UTILIZATION; HEART RATE; INSULIN SENSITIVITY; MITOCHONDRION; NONHUMAN; OBESITY; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PRIORITY JOURNAL; RAT; RAT STRAIN; RESPIRATORY CHAIN; SKELETAL MUSCLE;

ADENINE NUCLEOTIDES; ADIPOSE TISSUE; AMINO ACID SEQUENCE; ANIMALS; BLOOD GLUCOSE; BLOOD PRESSURE; DIETARY CARBOHYDRATES; DISEASE MODELS, ANIMAL; DNA, MITOCHONDRIAL; FATTY ACIDS, NONESTERIFIED; FRUCTOSE; GENETIC VARIATION; HAPLOTYPES; HEART RATE; HEREDITY; HYPERTENSION; INSULIN; INSULIN RESISTANCE; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; NADH DEHYDROGENASE; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; RATS; RATS, INBRED BN; RATS, INBRED F344; RATS, INBRED LEW; RATS, INBRED SHR;

EID: 84862127366     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00156.2011     Document Type: Article

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