-
1
-
-
0025663358
-
The pharmacology, metabolism, analysis, and applications of coumarin and coumarin-related compounds
-
Egan, D., O'Kennedy, R., Moran, E., Cox, D. et al., The pharmacology, metabolism, analysis, and applications of coumarin and coumarin-related compounds. Drug Metab. Rev. 1990, 22, 503-529.
-
(1990)
Drug Metab. Rev.
, vol.22
, pp. 503-529
-
-
Egan, D.1
O'Kennedy, R.2
Moran, E.3
Cox, D.4
-
2
-
-
0032767738
-
Coumarin metabolism, toxicity and carcinogenicity: relevance for human risk assessment
-
Lake, B. G., Coumarin metabolism, toxicity and carcinogenicity: relevance for human risk assessment. Food Chem. Toxicol. 1999, 37, 423-453.
-
(1999)
Food Chem. Toxicol.
, vol.37
, pp. 423-453
-
-
Lake, B.G.1
-
3
-
-
15044360544
-
Opinion of the scientific panel on food additives, flavourings, processing aids and materials in contacts with food (AFC) on a request from the commission related to coumarin
-
EFSA
-
EFSA, Opinion of the scientific panel on food additives, flavourings, processing aids and materials in contacts with food (AFC) on a request from the commission related to coumarin. EFSA J. 2004, 104, 1-36.
-
(2004)
EFSA J.
, vol.104
, pp. 1-36
-
-
-
4
-
-
79953308177
-
-
BfR, Consumers, who eat a lot of cinnamon, currently have an overly high exposure to coumarin. Health Assessment No. 043/2006
-
BfR, Consumers, who eat a lot of cinnamon, currently have an overly high exposure to coumarin. Health Assessment No. 043/2006, 2006.
-
(2006)
-
-
-
5
-
-
76749156320
-
Toxicology and risk assessment of coumarin: focus on human data
-
Abraham, K., Wöhrlin, F., Lindtner, O., Heinemeyer, G., Lampen, A., Toxicology and risk assessment of coumarin: focus on human data. Mol. Nutr. Food Res. 2010, 54, 228-239.
-
(2010)
Mol. Nutr. Food Res.
, vol.54
, pp. 228-239
-
-
Abraham, K.1
Wöhrlin, F.2
Lindtner, O.3
Heinemeyer, G.4
Lampen, A.5
-
6
-
-
80051843972
-
Quantification of free coumarin and its liberation from glucosylated precursors by stable isotope dilution assays based on liquid chromatography-tandem mass spectrometric detection
-
Rychlik, M., Quantification of free coumarin and its liberation from glucosylated precursors by stable isotope dilution assays based on liquid chromatography-tandem mass spectrometric detection. J. Agric. Food Chem. 2008, 56, 796-801.
-
(2008)
J. Agric. Food Chem.
, vol.56
, pp. 796-801
-
-
Rychlik, M.1
-
7
-
-
39749165640
-
HPLC analysis and safety assessment of coumarin in foods
-
Sproll, C., Ruge, W., Andlauer, C., Godelmann, R., Lachenmeier, D. W., HPLC analysis and safety assessment of coumarin in foods. Food Chem. 2008, 109, 462-469.
-
(2008)
Food Chem.
, vol.109
, pp. 462-469
-
-
Sproll, C.1
Ruge, W.2
Andlauer, C.3
Godelmann, R.4
Lachenmeier, D.W.5
-
8
-
-
78049314259
-
Quantification of flavoring constituents in cinnamon: high variation of coumarin in cassia bark from the German retail market and in authentic samples from Indonesia
-
Wöhrlin, F., Fry, H., Abraham, K., Preiss-Weigert, A., Quantification of flavoring constituents in cinnamon: high variation of coumarin in cassia bark from the German retail market and in authentic samples from Indonesia. J. Agric. Food Chem. 2010, 58, 10568-10575.
-
(2010)
J. Agric. Food Chem.
, vol.58
, pp. 10568-10575
-
-
Wöhrlin, F.1
Fry, H.2
Abraham, K.3
Preiss-Weigert, A.4
-
9
-
-
84988090440
-
Solvent-assisted supercritical fluid extraction for the isolation of semivolatile flavor compounds from cinnamons of commerce and their separation by series-coupled column gas chromatography
-
Miller, K. G., Poole, C. F., Chichila, T. M. P., Solvent-assisted supercritical fluid extraction for the isolation of semivolatile flavor compounds from cinnamons of commerce and their separation by series-coupled column gas chromatography. J. High. Resol. Chromatogr. 1995, 18, 461-471.
-
(1995)
J. High. Resol. Chromatogr.
, vol.18
, pp. 461-471
-
-
Miller, K.G.1
Poole, C.F.2
Chichila, T.M.P.3
-
10
-
-
35448990188
-
Zimt und Cumarin: eine Klarstellung aus wissenschaftlich-behördlicher Sicht
-
Abraham, K., Zimt und Cumarin: eine Klarstellung aus wissenschaftlich-behördlicher Sicht. Dtsch. Lebensmittel-Rundschau 2007, 103, 480-487.
-
(2007)
Dtsch. Lebensmittel-Rundschau
, vol.103
, pp. 480-487
-
-
Abraham, K.1
-
11
-
-
79953328643
-
-
SKLM (Senatskommission zur Beurteilung der gesundheitlichen Unbedenklichkeit von Lebensmitteln), natural constituents of foods: assessing the toxicity of substances administered as pure compounds compared to their ingestion as inherent food components. Statement of the DFG-Senate commission on Food Safety.
-
SKLM (Senatskommission zur Beurteilung der gesundheitlichen Unbedenklichkeit von Lebensmitteln), natural constituents of foods: assessing the toxicity of substances administered as pure compounds compared to their ingestion as inherent food components. Statement of the DFG-Senate commission on Food Safety. 2006.
-
(2006)
-
-
-
12
-
-
85078393980
-
Guidance on safety assessment of botanicals and botanical preparations intended for use as ingredients in food supplements
-
EFSA Scientific Committee..
-
EFSA Scientific Committee. Guidance on safety assessment of botanicals and botanical preparations intended for use as ingredients in food supplements. EFSA J. 2009, 7, 1249.
-
(2009)
EFSA J.
, vol.7
, pp. 1249
-
-
-
13
-
-
0033521964
-
Lack of effect of coumarin in women with lymphedema after treatment for breast cancer
-
Loprinzi, C. L., Kugler, J. W., Sloan, J. A., Rooke, T. W. et al., Lack of effect of coumarin in women with lymphedema after treatment for breast cancer. N. Engl. J. Med. 1999, 340, 346-350.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 346-350
-
-
Loprinzi, C.L.1
Kugler, J.W.2
Sloan, J.A.3
Rooke, T.W.4
-
14
-
-
0037951342
-
Safety aspects of a coumarin-troxerutin combination regarding liver function in a double-blind placebo-controlled study
-
Schmeck-Lindenau, H. J., Naser-Hijazi, B., Becker, E. W., Henneicke-von Zepelin, H. H., Schnitker, J., Safety aspects of a coumarin-troxerutin combination regarding liver function in a double-blind placebo-controlled study. Int. J. Clin. Pharmacol. Ther. 2003, 41, 193-199.
-
(2003)
Int. J. Clin. Pharmacol. Ther.
, vol.41
, pp. 193-199
-
-
Schmeck-Lindenau, H.J.1
Naser-Hijazi, B.2
Becker, E.W.3
Henneicke-von Zepelin, H.H.4
Schnitker, J.5
-
15
-
-
79953307346
-
-
EMA (European Medicines Agency). Guideline on the investigation of bioequivalence.
-
EMA (European Medicines Agency). Guideline on the investigation of bioequivalence. 2010.
-
(2010)
-
-
-
16
-
-
0017608619
-
Pharmacokinetics of coumarin and its 7-hydroxy-metabolites upon intravenous and peroral administration of coumarin in man
-
Ritschel, W. A., Brady, M. E., Tan, H. S., Hoffmann, K. A. et al., Pharmacokinetics of coumarin and its 7-hydroxy-metabolites upon intravenous and peroral administration of coumarin in man. Eur. J. Clin. Pharmacol. 1977, 12, 457-461.
-
(1977)
Eur. J. Clin. Pharmacol.
, vol.12
, pp. 457-461
-
-
Ritschel, W.A.1
Brady, M.E.2
Tan, H.S.3
Hoffmann, K.A.4
-
17
-
-
0018413880
-
First-pass effect of coumarin in man
-
Ritschel, W. A., Brady, M. E., Tan, H. S., First-pass effect of coumarin in man. Int. J. Clin. Pharmacol. Biopharm. 1979, 17, 99-103.
-
(1979)
Int. J. Clin. Pharmacol. Biopharm.
, vol.17
, pp. 99-103
-
-
Ritschel, W.A.1
Brady, M.E.2
Tan, H.S.3
-
18
-
-
0034599544
-
CYP2A6: a human coumarin 7-hydroxylase
-
Pelkonen, O., Rautio, A., Raunio, H., Pasanen, M., CYP2A6: a human coumarin 7-hydroxylase. Toxicology 2000, 144, 139-147.
-
(2000)
Toxicology
, vol.144
, pp. 139-147
-
-
Pelkonen, O.1
Rautio, A.2
Raunio, H.3
Pasanen, M.4
-
19
-
-
0026934672
-
Interindividual variability of coumarin 7-hydroxylation in healthy volunteers
-
Rautio, A., Kraul, H., Kojo, A., Salmela, E., Pelkonen, O., Interindividual variability of coumarin 7-hydroxylation in healthy volunteers. Pharmacogenetics 1992, 2, 227-233.
-
(1992)
Pharmacogenetics
, vol.2
, pp. 227-233
-
-
Rautio, A.1
Kraul, H.2
Kojo, A.3
Salmela, E.4
Pelkonen, O.5
-
20
-
-
0028218139
-
Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers
-
Merkel, U., Sigusch, H., Hoffmann, A., Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers. Eur. J. Clin. Pharmacol. 1994, 46, 175-177.
-
(1994)
Eur. J. Clin. Pharmacol.
, vol.46
, pp. 175-177
-
-
Merkel, U.1
Sigusch, H.2
Hoffmann, A.3
-
21
-
-
76749141073
-
scientific opinion of the panel on food additives, flavourings, processing aids and materials in contact with food on a request from the European Commission on coumarin in flavourings and other food ingredients with flavouring properties
-
EFSA
-
EFSA, scientific opinion of the panel on food additives, flavourings, processing aids and materials in contact with food on a request from the European Commission on coumarin in flavourings and other food ingredients with flavouring properties. EFSA J. 2008, 793, 1-15.
-
(2008)
EFSA J.
, vol.793
, pp. 1-15
-
-
-
22
-
-
0026454446
-
Rapid and sensitive determination of coumarin and 7-hydroxycoumarin and its glucuronide conjugate in urine and plasma by high-performance liquid chromatography
-
Egan, D. A., O'Kennedy, R., Rapid and sensitive determination of coumarin and 7-hydroxycoumarin and its glucuronide conjugate in urine and plasma by high-performance liquid chromatography. J Chromatogr. 1992, 582, 137-143.
-
(1992)
J Chromatogr.
, vol.582
, pp. 137-143
-
-
Egan, D.A.1
O'Kennedy, R.2
-
23
-
-
46749104406
-
Bioavailability and bioequivalence: focus on physiological factors and variability
-
Karalis, V., Macheras, P., Van Peer, A., Shah, V. P., Bioavailability and bioequivalence: focus on physiological factors and variability. Pharm. Res. 2008, 25, 1956-1962.
-
(2008)
Pharm. Res.
, vol.25
, pp. 1956-1962
-
-
Karalis, V.1
Macheras, P.2
Van Peer, A.3
Shah, V.P.4
-
24
-
-
0030743727
-
Percutaneous absorption and metabolism of coumarin in human and rat skin
-
Yourick, J. J., Bronaugh, R. L., Percutaneous absorption and metabolism of coumarin in human and rat skin. J. Appl. Toxicol. 1997, 17, 153-158.
-
(1997)
J. Appl. Toxicol.
, vol.17
, pp. 153-158
-
-
Yourick, J.J.1
Bronaugh, R.L.2
-
25
-
-
0029987971
-
Coumarin 7-hydroxylation in long-term adherents of a strict uncooked vegan diet
-
Rauma, A. L., Rautio, A., Pasanen, M., Pelkonen, O. et al., Coumarin 7-hydroxylation in long-term adherents of a strict uncooked vegan diet. Eur. J. Clin. Pharmacol. 1996, 50, 133-137.
-
(1996)
Eur. J. Clin. Pharmacol.
, vol.50
, pp. 133-137
-
-
Rauma, A.L.1
Rautio, A.2
Pasanen, M.3
Pelkonen, O.4
-
26
-
-
0014675753
-
Metabolism of coumarin in man
-
Shilling, W. H., Crampton, R. F., Longland, R. C., Metabolism of coumarin in man. Nature 1969, 221, 664-665.
-
(1969)
Nature
, vol.221
, pp. 664-665
-
-
Shilling, W.H.1
Crampton, R.F.2
Longland, R.C.3
-
27
-
-
0032126167
-
Determination of 2-hydroxyphenylacetic acid (2HPAA) in urine after oral and parenteral administration of coumarin by gas-liquid chromatography with flame-ionization detection
-
Meineke, I., Desel, H., Kahl, R., Kahl, G. F., Gundert-Remy, U., Determination of 2-hydroxyphenylacetic acid (2HPAA) in urine after oral and parenteral administration of coumarin by gas-liquid chromatography with flame-ionization detection. J. Pharm. Biomed. Anal. 1998, 17, 487-492.
-
(1998)
J. Pharm. Biomed. Anal.
, vol.17
, pp. 487-492
-
-
Meineke, I.1
Desel, H.2
Kahl, R.3
Kahl, G.F.4
Gundert-Remy, U.5
-
28
-
-
62549115713
-
CYP2A6 genotypes and coumarin-oxidation phenotypes in a Thai population and their relationship to tobacco smoking
-
Mahavorasirikul, W., Tassaneeyakul, W., Satarug, S., Reungweerayut, R. et al., CYP2A6 genotypes and coumarin-oxidation phenotypes in a Thai population and their relationship to tobacco smoking. Eur. J. Clin. Pharmacol. 2009, 65, 377-384.
-
(2009)
Eur. J. Clin. Pharmacol.
, vol.65
, pp. 377-384
-
-
Mahavorasirikul, W.1
Tassaneeyakul, W.2
Satarug, S.3
Reungweerayut, R.4
|