Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice

Journal of Biological Chemistry

Volumn 287, Issue 24, 2012, Pages 20755-20768

  Hager, Lauren ^a,b   Li, Lixin ^a   Pun, Henry ^a   Liu, Lu ^a   Hossain, Mohammad A ^a   Maguire, Graham F ^a   Naples, Mark ^c   Baker, Chris ^c   Magomedova, Lilia ^d   Tam, Jonathan ^a   Adeli, Khosrow ^b,c   Cummins, Carolyn L ^d   Connelly, Philip W ^a,b   Ng, Dominic S ^a,b  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL LEVELS; CHOLESTEROL METABOLISM; ENDOPLASMIC RETICULUM STRESS; ER STRESS; FREE CHOLESTEROLS; HEPATIC INSULIN RESISTANCE; HEPATIC TISSUE; INSULIN RESISTANCE; KNOCK OUTS; UP-REGULATION; WILD-TYPE CONTROLS;

CELL MEMBRANES; ELECTRIC RESISTANCE; GENE EXPRESSION; INSULIN; MAMMALS; NUTRITION; PHOSPHOLIPIDS; TISSUE;

CHOLESTEROL;

CHOLESTEROL; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PHOSPHATIDYLCHOLINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL CELL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE EXPRESSION; GLUCOSE TOLERANCE; INSULIN RESISTANCE; LIPOPROTEIN BLOOD LEVEL; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTEROL; DIETARY FATS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; INSULIN RESISTANCE; LECITHIN ACYLTRANSFERASE DEFICIENCY; LIPOPROTEINS; LIVER; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; RECEPTORS, LDL; RNA, MESSENGER; STEROL O-ACYLTRANSFERASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

MUS;

EID: 84862021619     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.340919     Document Type: Article

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