Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair

Journal of Molecular Biology

Volumn 420, Issue 3, 2012, Pages 204-219

  Strop, Pavel ^a   Ho, Wei Hsien ^a   Boustany, Leila M ^a   Abdiche, Yasmina N ^a   Lindquist, Kevin C ^a   Farias, Santiago E ^a   Rickert, Mathias ^a   Appah, Charles Takeshi ^a   Pascua, Edward ^a   Radcliffe, Teresa ^a   Sutton, Janette ^a   Chaparro Riggers, Javier ^a   Chen, Wei ^a   Casas, Meritxell Galindo ^a   Chin, Sherman Michael ^a   Wong, Oi Kwan ^a   Liu, Shu Hui ^a   Vergara, German ^a   Shelton, Dave ^a   Rajpal, Arvind ^a   Pons, Jaume ^a   more..

^a PFIZER INC   (United States)

Author keywords

bispecific antibodies; CD20; CD3; Fab arm exchange; Fc heterodimer

Indexed keywords

BISPECIFIC ANTIBODY; CD20 ANTIBODY; CD3 ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY ENGINEERING; ARTICLE; B LYMPHOCYTE; FEMALE; HUMAN; HUMAN CELL; HYBRIDOMA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STANDARD; WILD TYPE;

EID: 84862015979     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.04.020     Document Type: Article

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