Contribution of domain interface residues to the stability of antibody C(H)3 domain homodimers

Biochemistry

Volumn 37, Issue 26, 1998, Pages 9266-9273

  Dall'Acqua, William ^a   Simon, Alexander L ^a,b   Mulkerrin, Michael G ^a   Carter, Paul ^a  

^a GENENTECH INC   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1;

ANTIBODY STRUCTURE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DIMERIZATION; DISSOCIATION; ESCHERICHIA COLI; GENE MUTATION; IMMUNOGLOBULIN STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STABILITY;

ALANINE; AMINO ACID SUBSTITUTION; CIRCULAR DICHROISM; DIMERIZATION; DNA MUTATIONAL ANALYSIS; HUMANS; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

ESCHERICHIA COLI;

EID: 0032581013     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980270i     Document Type: Article

References (78)

1. Davies, D. R., Padlan, E., and Sheriff, S. (1990) Annu. Rev. Biochem. 59, 439-473.
2. Mariuzza, R. A., and Poljak, R. J. (1993) Curr. Opin. Immunol. 5, 50-55.
3. Webster, D. M., Henry, A. H., and Rees, A. R. (1994) Curr. Opin. Struct. Biol. 4, 123-129.
4. Braden, B. C., and Poljak, R. J. (1995) FASEB J. 9, 9-16.
5. Clackson, T., and Wells, J. A. (1995) Science 267, 383-386.
6. Muller, Y. A., Li, B., Christinger, H. W., Wells, J. A., Cunningham, B. C., and de Vos, A. M. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 7192-7197.
7. Dall'Acqua, W., Goldman, E. R., Eisenstein, E., and Mariuzza, R. A. (1996) Biochemistry 35, 9667-9676.
8. Goodsell, D. S., and Olson, A. J. (1993) Trends Biochem. Sci. 18, 65-68.
9. Deonarain, M. P., Scrutton, N. S., and Perham, R. N. (1992) Biochemistry 31, 1491-1497.
10. Deonarain, M. P., Scrutton, N. S., and Perham, R. N. (1992) Biochemistry 31, 1498-1504.
11. Elsevier, J. P., Wells, L., Quimby, B. B., and Fridovich-Keil, J. E. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 7166-7171.
12. Bird, R. E., Hardman, K. D., Jacobson, J. W., Johnson, S., Kaufman, B. M., Lee, S. M., Lee, T., Pope, S. H., Riordan, G. S., and Whitlow, M. (1988) Science 242, 423-426.
13. Huston, J. S., Levinson, D., Mudgett-Hunter, M., Tai, M. S., Novotny, J., Margolies, M. N., Ridge, R. J., Bruccoleri, R. E., Haber, E., and Crea, R. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 5879-5883.
14. Deisenhofer, J. (1981) Biochemistry 20, 2361-2370.
15. Miller, S. (1990) J. Mol. Biol. 216, 965-973.
16. Carter, P., and Wells, J. A. (1988) Nature 332, 564-568.
17. Duncan, A. R., and Winter. G. (1988) Nature 332, 563-564.
18. Cunningham, B. C., and Wells, J. A. (1989) Science 244, 1081-1085.
19. Atwell, S., Ridgway, J. B. B., Wells, J. A., and Carter, P. (1997) J. Mol. Biol. 270, 26-35.
20. Hochuli, E. (1988) J. Chromatogr. 444, 293-302.
21. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5467.
22. Kunkel, T. A., Roberts, J. D., and Zakour, R. A. (1987) Methods Enzymol. 154, 367-382.
23. Rodrigues, M. L., Presta, L. G., Kotts, C. E., Wirth, C., Mordenti, J., Osaka, G., Wong, W. L. T., Nuijens, A., Blackburn, B., and Carter, P. (1995) Cancer Res. 55, 63-70.
24. Carter P., Kelley, R. F., Rodrigues, M. E., Snedecor, B., Covarrubias, M., Velligan, M. D., Wong, W. L. T., Rowland, A. M., Kotts, C. E., Carver, M. E., Yang, M., Bourell, J. H., Shephard, H. M., and Henner, D. (1992) Bio/Technology 10, 163-168.
25. Zhukovsky, E. A., Mulkerrin, M. G., and Presta, L. G. (1994) Biochemistry 33, 9856-9864.
26. Nozaki, Y. (1972) Methods Enzymol. 26, 43-50.
27. Santoro, M. M., and Bolen, D. W. (1988) Biochemistry 27, 8063-8068.
28. Barrick, D., and Baldwin, R. L. (1993) Biochemistry 32, 3790-3796.
29. Greene, R. F., and Pace, C. N. (1974) J. Biol. Chem. 249, 5388-5393.
30. Kellis, J. T., Jr., Nyberg, K., and Fersht, A. R. (1989) Biochemistry 28, 4914-4922.
31. Horovitz, A., Matthews, J. M., and Fersht, A. R. (1992) J. Mol. Biol. 227, 560-568.
32. Serrano, L., Horovitz, A., Avron, B., Bycroft, M., and Fersht, A. R. (1990) Biochemistry 29, 9343-9352.
33. Bourell, J. H., Clauser, K. P., Kelley, R., Carter, P., and Stults, J. T. (1994) Anal. Chem. 66, 2088-2095.
34. Venyaminov, S. Y., and Yang, J. S. (1996) in Circular Dichroism and the Conformational Analysis of Biomolecules, pp 69-107, Plenum Press, New York.
35. Missiakas, D., Betton, J. M., Minard, P., and Yon, J. M. (1990) Biochemistry 29, 8683-8689.
36. Glockshuber, R., Malia, M., Pfitzinger, I., and Pluckthun, A. A. (1990) Biochemistry 29, 1362-1367.
37. Robinson, C. R., and Sauer, R. T. (1996) Biochemistry 35, 13878-13884.
38. Provencher, S. W., and Glockner, J. (1981) Biochemistry 20, 33-37.
39. Manning, M. C., and Woody, R. W. (1987) Biopolymers 26, 1731-1752.
40. Manning, M. C., Illangasekare, M., and Woody, R. W. (1988) Biophys. Chem. 31, 77-86.
41. Ellerson, J. R., Yasmeen, D., Painter, R. H., and Dorrington, K. J. (1976) J. Immunol. 116, 510-517.
42. Schiffer M., Chang, C. H., Naik, V. M., and Stevens, F. J. (1988) J. Mol. Biol. 203, 799-802.
43. Holliger, P., Prospero, T., and Winter, G. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 6444-6448.
44. Whitlow, M., Filpula, D., Rollence, M. L., Feng, S. L., and Wood J. F. (1994) Protein Eng. 7, 1017-1026.
45. Desplancq, D., King, D. J., Lawson, A. D. G., and Mountain, A. (1994) Protein Eng. 7, 1027-1033.
46. Fersht, A. R., Shi, J., Knill-Jones, J., Lowe, D. M., Wilkinson, A. J., Blow, D. M., Brick, P., Carter, P., Waye, M. M. Y., and Winter, G. (1985) Nature 314, 235-238.
47. Street, I. P. Armstrong, C. R., and Withers, S. G. (1986) Biochemistry 25, 6021-6027.
48. Shirley, B. A., Stanssens, P., Hahn, U., and Pace, C. N. (1992) Biochemistry 31, 725-732.
49. Goldman, E. R., Dall'Acqua, W., Braden, B. C., and Mariuzza, R. A. (1997) Biochemistry 36, 49-56.
50. Ackers, G. K., and Smith, F. R. (1985) Annu. Rev. Biochem. 54, 597-629.
51. Fersht, A. R. (1988) Biochemistry 27, 1577-1580.
52. Eriksson, A. E., Baase, W. A., Zhang, X. J., Heinz, D. W., Blaber M., Baldwin. E. P., and Matthews, B. W. (1992) Science 255, 178-183.
53. Rashin, A. A., Rashin, B. H., Rashin, A., and Abagyan, R. (1997) Protein Sci. 6, 2143-2158.
54. Atwell, S., Ultsch, M., de Vos, A. M., and Wells, J. A. (1997) Science 278, 1125-1128.
55. Ysern, X., Fields, B. A., Bhat, T. N., Goldbaum, F. A., Dall'Acqua, W., Schwartz, F. P., Poljak, R. J., and Mariuzza, R. A. (1994) J. Mol. Biol. 238, 496-500.
56. Ross, P. D., and Subramanian, S. (1981) Biochemistry 20, 3096-3102.
57. Bhat, T. N., Bentley, G. A., Boulot, G., Greene, M. I., Tello, D., Dall'Acqua, W., Souchon, H., Schwartz, F. P., Mariuzza, R. A., and Poljak, R. J. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 1089-1093.
58. Koshy T. I., Luntz, T. L., Schejter, A., and Margoliash, E. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 8697-8701.
59. Schejter, A., Luntz, T. L., Koshy, T. I., and Margoliash, E. (1992) Biochemistry 31, 8336-8343.
60. Lascu, I., Deville-Bonne, D., Glaser, P., and Veron, M. (1993) J. Biol. Chem. 268, 20268-20275.
61. Alber, T. (1989) Annu. Rev. Biochem. 58, 765-798.
62. Shortle, D., and Meeker, A. K. (1986) Proteins: Struct., Funct., Genet. 1, 81-89.
63. Wells, J. A. (1991) Methods Enzymol. 202, 390-414.
64. Schreiber, G., and Fersht, A. R. (1995) J. Mol. Biol. 248, 478-486.
65. Green, S. M., and Shortle, D. (1993) Biochemistry 32, 10131-10139.
66. Speros, P. C., LiCata, V. J., Yontani, T., and Ackers, G. K. (1991) Biochemistry 30, 7254-7262.
67. LiCata, V. J., and Ackers, G. K. (1995) Biochemistry 34, 3133-3139.
68. Fields, B. A., Goldbaum, F. A., Dall'Acqua, W., Malchiodi, E. L., Cauerhff, A., Schwartz, F. P., Ysern, X., Poljak, R. J., and Mariuzza, R. A. (1996) Biochemistry 35, 15494-15503.
69. Cunningham, B. C., and Wells, J. A. (1993) J. Mol. Biol. 234, 554-563.
70. Chothia, C., and Janin, J. (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 4146-4150.
71. Chothia, C., Novotny, J., Bruccoleri, R., and Karplus, M. (1985) J. Mol. Biol. 186, 651-663.
72. Janin, J., and Chothia, C. (1990) J. Biol. Chem. 265, 16027-16030.
73. Wilson, L. A., and Stanfield, R. L. (1993) Curr. Opin. Struct. Biol. 3, 113-118.
74. Davies, D. R., and Cohen, G. H. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 7-12.
75. Ellison, J. W., Berson, B. J., and Hood, L. E. (1982) Nucleic Acids Res. 10, 4071-4079.
76. Chang, C. N., Kuang, W. J., and Chen, E. Y. (1986) Gene 44, 121-125.
77. Picken, R. N., Mazaitis, A. J., Maas, W. K., Rey, M., and Heyneker, H. (1983) Infect. Immun. 42, 269-275.
78. Rabat, E. A., Wu, T. T., Perry, H. M., Gottesman, K. S., and Foeller, C. (1991) Sequences of Proteins of Immunological Interest, 5th ed., Vol. 1, pp 688-696. National Institutes of Health, Bethesda, MD.