-
1
-
-
55249095625
-
Myeloproliferative disorders
-
Levine RL, Gilliland DG. Myeloproliferative disorders. Blood 2008; 112: 2190-2198.
-
(2008)
Blood
, vol.112
, pp. 2190-2198
-
-
Levine, R.L.1
Gilliland, D.G.2
-
2
-
-
33846037739
-
Oncogenic mechanisms in myeloproliferative disorders
-
DOI 10.1007/s00018-006-6272-7
-
Delhommeau F, Pisani DF, James C, Casadevall N, Constantinescu S, Vainchenker W. Oncogenic mechanisms in myeloproliferative disorders. Cell Mol Life Sci 2006; 63: 2939-2953. (Pubitemid 46072300)
-
(2006)
Cellular and Molecular Life Sciences
, vol.63
, Issue.24
, pp. 2939-2953
-
-
Delhommeau, F.1
Pisani, D.F.2
James, C.3
Casadevall, N.4
Constantinescu, S.5
Vainchenker, W.6
-
3
-
-
33744490974
-
Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model
-
DOI 10.1182/blood-2005-12-4824
-
Wernig G, Mercher T, Okabe R, Levine RL, Lee BH, Gilliland DG. Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model. Blood 2006; 107: 4274-4281. (Pubitemid 43801351)
-
(2006)
Blood
, vol.107
, Issue.11
, pp. 4274-4281
-
-
Wernig, G.1
Mercher, T.2
Okabe, R.3
Levine, R.L.4
Lee, B.H.5
Gilliland, D.G.6
-
4
-
-
34447627350
-
TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations
-
DOI 10.1038/sj.leu.2404750, PII 2404750
-
Pardanani A, Hood J, Lasho T, Levine RL, Martin MB, Noronha G et al. TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations. Leukemia 2007; 21: 1658-1668. (Pubitemid 47086756)
-
(2007)
Leukemia
, vol.21
, Issue.8
, pp. 1658-1668
-
-
Pardanani, A.1
Hood, J.2
Lasho, T.3
Levine, R.L.4
Martin, M.B.5
Noronha, G.6
Finke, C.7
Mak, C.C.8
Mesa, R.9
Zhu, H.10
Soll, R.11
Gilliland, D.G.12
Tefferi, A.13
-
5
-
-
70350123034
-
Chronic myeloproliferative diseases with and without the Ph chromosome: Some unresolved issues
-
Goldman JM, Green AR, Holyoake T, Jamieson C, Mesa R, Mughal T et al. Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues. Leukemia 2009; 23: 1708-1715.
-
(2009)
Leukemia
, vol.23
, pp. 1708-1715
-
-
Goldman, J.M.1
Green, A.R.2
Holyoake, T.3
Jamieson, C.4
Mesa, R.5
Mughal, T.6
-
6
-
-
33746437130
-
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
-
Pikman Y, Lee BH, Mercher T, McDowell E, Ebert BL, Gozo M et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med 2006; 3: e270.
-
(2006)
PLoS Med
, vol.3
-
-
Pikman, Y.1
Lee, B.H.2
Mercher, T.3
McDowell, E.4
Ebert, B.L.5
Gozo, M.6
-
7
-
-
70350446987
-
Phospho-STAT5 and phospho-Akt expression in chronic myeloproliferative neoplasms
-
Grimwade LF, Happerfield L, Tristram C, McIntosh G, Rees M, Bench AJ et al. Phospho-STAT5 and phospho-Akt expression in chronic myeloproliferative neoplasms. Br J Haematol 2009; 147: 495-506.
-
(2009)
Br J Haematol
, vol.147
, pp. 495-506
-
-
Grimwade, L.F.1
Happerfield, L.2
Tristram, C.3
McIntosh, G.4
Rees, M.5
Bench, A.J.6
-
8
-
-
84862005018
-
Developing pharmacological modulators of STAT signaling
-
Stephanou A (ed) Landes Bioscience: Austin
-
Nelson EA, Frank DA. Developing pharmacological modulators of STAT signaling. In: Stephanou A (ed). JAK-STAT Pathway in Disease. Landes Bioscience: Austin, 2009, pp 164-172.
-
(2009)
JAK-STAT Pathway in Disease
, pp. 164-172
-
-
Nelson, E.A.1
Frank, D.A.2
-
9
-
-
77949331464
-
STAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F mutant
-
Funakoshi-Tago M, Tago K, Abe M, Sonoda Y, Kasahara T. STAT5 activation is critical for the transformation mediated by myeloproliferative disorder-associated JAK2 V617F mutant. J Biol Chem 2010; 285: 5296-5307.
-
(2010)
J Biol Chem
, vol.285
, pp. 5296-5307
-
-
Funakoshi-Tago, M.1
Tago, K.2
Abe, M.3
Sonoda, Y.4
Kasahara, T.5
-
10
-
-
79953109597
-
The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors
-
Nelson EA, Walker SR, Weisberg E, Bar-Natan M, Barrett R, Gashin LB et al. The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors. Blood 2011; 117: 3421-3429.
-
(2011)
Blood
, vol.117
, pp. 3421-3429
-
-
Nelson, E.A.1
Walker, S.R.2
Weisberg, E.3
Bar-Natan, M.4
Barrett, R.5
Gashin, L.B.6
-
11
-
-
67651006461
-
Kinome profiling in pediatric brain tumors as a new approach for target discovery
-
Sikkema AH, Diks SH, den Dunnen WF, ter Elst A, Scherpen FJ, Hoving EW et al. Kinome profiling in pediatric brain tumors as a new approach for target discovery. Cancer Res 2009; 69: 5987-5995.
-
(2009)
Cancer Res
, vol.69
, pp. 5987-5995
-
-
Sikkema, A.H.1
Diks, S.H.2
Den Dunnen, W.F.3
Ter Elst, A.4
Scherpen, F.J.5
Hoving, E.W.6
-
12
-
-
0034693871
-
Janus kinases: Components of multiple signaling pathways
-
Rane SG, Reddy EP. Janus kinases: components of multiple signaling pathways. Oncogene 2000; 19: 5662-5679.
-
(2000)
Oncogene
, vol.19
, pp. 5662-5679
-
-
Rane, S.G.1
Reddy, E.P.2
-
13
-
-
57749084579
-
Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2
-
Gozgit JM, Bebernitz G, Patil P, Ye M, Parmentier J, Wu J et al. Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2. J Biol Chem 2008; 283: 32334-32343.
-
(2008)
J Biol Chem
, vol.283
, pp. 32334-32343
-
-
Gozgit, J.M.1
Bebernitz, G.2
Patil, P.3
Ye, M.4
Parmentier, J.5
Wu, J.6
-
14
-
-
73949096431
-
FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation
-
Yoshimoto G, Miyamoto T, Jabbarzadeh-Tabrizi S, Iino T, Rocnik JL, Kikushige Y et al. FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation. Blood 2009; 114: 5034-5043.
-
(2009)
Blood
, vol.114
, pp. 5034-5043
-
-
Yoshimoto, G.1
Miyamoto, T.2
Jabbarzadeh-Tabrizi, S.3
Iino, T.4
Rocnik, J.L.5
Kikushige, Y.6
|