Peroxidase-like activity of uncoupled cytochrome P450: Studies with bilirubin and toxicological implications of uncoupling

Biochemical Pharmacology

Volumn 84, Issue 3, 2012, Pages 374-382

  De Matteis, Francesco ^a,b,c   Ballou, David P ^b   Coon, Minor J ^b   Estabrook, Ronald W ^c   Haines, Donovan C ^d  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d SAM HOUSTON STATE UNIVERSITY   (United States)

Author keywords

Bilirubin oxidation; BM3; Cytochrome P450; NADPH O 2 consumption ratio; Perfluorolaurate; Uncoupling

Indexed keywords

BILIRUBIN; BILIVERDIN; CYTOCHROME P450; LAURIC ACID DERIVATIVE; PERFLUOROLAURIC ACID; PEROXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; HYDROXYLATION; OXIDATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

BACILLUS MEGATERIUM; BILIRUBIN; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME ACTIVATION; NADP; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; PEROXIDASE; UNCOUPLING AGENTS;

EID: 84861962921     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.04.016     Document Type: Article

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