Functional interactions in cytochrome P450BM3. Fatty acid substrate binding alters electron-transfer properties of the flavoprotein domain

Biochemistry

Volumn 35, Issue 47, 1996, Pages 15029-15037

  Murataliev, Marat B ^a   Feyereisen, René ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DICHLOROPHENOLINDOPHENOL; CARBON MONOXIDE; CYTOCHROME C; CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; FATTY ACID; FERRICYANIDE; FLAVINE ADENINE NUCLEOTIDE; FLAVINE MONONUCLEOTIDE; FLAVOPROTEIN; HEME; HYBRID PROTEIN; LAURIC ACID; OXYGEN; OXYGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; FLUORESCENCE; HYDROXYLATION; NONHUMAN; PRIORITY JOURNAL;

BACTERIAL PROTEINS; CARBON MONOXIDE; CATALYSIS; CYTOCHROME C GROUP; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRON TRANSPORT; ESCHERICHIA COLI; FATTY ACIDS; FLAVOPROTEINS; HEME; HYDROXYLATION; LAURIC ACIDS; MIXED FUNCTION OXYGENASES; NADP; OXIDATION-REDUCTION; PROTEIN BINDING; SPECTROMETRY, FLUORESCENCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0030446061     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961667u     Document Type: Article

References (29)

1. Black. S. D., Linger, M. H., Freck, L. C., Kazemi. S., & Galbaith, J. A. (1994) Arch. Biochem. Biophys. 310, 126-133.
2. Boddupalli, S. S., Estabrook, R. W., & Peterson, J. A. (1990) J. Biol. Chem. 265, 4233-4239.
3. Boddupalli. S. S., Oster, T., Estabrook, R. W., & Peterson, J. A. (1992) J. Biol. Chem. 267, 10375-10380.
4. Hare, R. S., & Fulco, A. J. (1975) Biochem. Biophys. Res. Commun. 65, 665-672.
5. Ho, P. P., & Fulco, A. J. (1976) Biochim. Biophys. Acta 431, 239-256.
6. Klein, M. L., & Fulco, A. J. (1993) J. Biol. Chem. 268, 7553-7561.
7. Klein, M. L., & Fulco, A. J. (1994) Biochim. Biophys. Acta 1201, 245-250.
8. Kurzban, G. P., & Strobel, H. W. (1986) J. Biol. Chem. 261, 7824-7830.
9. Li, H., & Poulos, T. L. (1995) Acta Crystallogr. D51, 21-32.
10. Li, H., Darwish, K., & Poulos, T. L. (1991) J. Biol. Chem. 266, 11909-11914.
11. Lowry, O. H., Rosebrough, N. J., Farr, A. L., & Randall., R. J. (1951) J. Biol. Chem. 195, 265-275.
12. Matson, R. S., Hare, R. S., & Fulco, A. J. (1977) Biochim. Biophvs. Acta 487, 487-494.
13. Miles, J. S., Munro, A. W., Rospendowski, B. N., Smith, W. E., McKnight, J., & Thomson, A. J. (1992) Biochem. J. 288, 503-509.
14. Miura, Y., & Fulco, A. J (1974) J. Biol. Chem. 249, 1880-1888.
15. Modi, S., Sutcliffe, M. J., Primrose, W. U., Lian, L. Y., & Roberts, G. C. K. (1996) Nat. Struct. Biol. 3, 414-417.
16. Mueller, E. J., Loida, P. J., & Sligar, S. G. (1995) in Cytochrome P450. Structure, Mechanism, and Biochemistry (Ortiz de Montellano, P. R., Ed.) pp 83-124, Plenum Pres, New York, 83-124.
17. Munro, A. W., Lindsay, J. G., Coggins, J. R., Kelly, S. M., & Price, N. C. (1994) FEBS Lett. 343, 70-74.
18. Munro, A. W., Lindsay, J. G., Coggins, J. R., Kelly, S. M., & Price, N. C. (1995) Biochim. Biophys. Acta 1231, 255-264.
19. Narhi, L. O., & Fulco, A. J. (1986) J. Biol. Chem. 261, 7160-7169.
20. Narhi, L. O., & Fulco, A. J. (1987) J. Biol. Chem. 262, 6683-6690.
21. Narhi, L. O., Wen, L.-P., & Fulco, A. J. (1988) Mol. Cell Biochem. 79, 63-71.
22. Nelson, D. R., Koymans, L., Kamataki, T., Stegeman, J. J., Feyereisen, R., Waxman, D. J., Waterman, M. R., Gotoh, O., Coon, M. J., Estabrook, R. W., Gunsalus, I. C., & Nebert, D. W. (1996) Pharmacogenetics 6, 1-42.
23. Paulsen, M. D. & Ornstein, R. L. (1995) Proteins: Struct., Funct., Genet. 21, 237-243.
24. Porter, T. D. (1991) Trends Biochem. Sci. 16, 154-158.
25. Ravichandran, K. G., Boddupalli, S. S., Haseman, C. A., Peterson, J. A., & Deisenhofer, J. (1993) Science 261, 731-736.
26. Sevrioukova, I. F., & Peterson, J. A. (1995) Biochimie 77, 562-572.
27. Sevrioukova, I., Shaffer, C., Ballou, D. P., & Peterson, J. A. (1996) Biochemistry 35, 7058-7068.
28. Vermilion, J. L., Ballou, D. P., Massey, V., & Coon, M. J. (1981) J. Biol. Chem. 256, 266-277.
29. Wen, L.-P., & Fulco, A. J. (1987) J. Biol. Chem. 262, 6676-6682.