Oxygen activation by cytochrome P450(BM-3): Effects of mutating an active site acidic residue

Archives of Biochemistry and Biophysics

Volumn 337, Issue 2, 1997, Pages 209-216

  Yeom, Hyeyeong ^a   Sligar, Stephen G ^a,b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; CYTOCHROME P450; LAURIC ACID; MUTANT PROTEIN; MYRISTIC ACID; PALMITIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ABSORPTION SPECTROSCOPY; ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; GENE MUTATION; HYDROXYLATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0031568234     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.9763     Document Type: Article

References (34)

1. 1. Narhi, L. O., and Fulco, A. J. (1986) J. Biol. Chem. 261, 7160-7169.
2. 2. Miura, Y., and Fulco, A. J. (1975) Biochim. Biophys. Acta 388, 305-317.
3. 3. Ravichandran, K. G., Bouddupalli, S. S., Hasemann, C. A., Peterson, J. A., and Deisenhofer, J. (1993) Science 261, 731-736.
4. 4. Narhi, L. O., and Fulco, A. J. (1987) J. Biol. Chem. 262, 6683-6690.
5. 5. Peterson, J. A., Graham-Lorence, S., Turan, G., and Capdevila, J. (1995) in Third International Symposium Cytochrome P450 Diversity, Woodshole, MA.
6. 6. Ragg, R., and Poulos, T. L. (1989) Biochemistry 28, 7586-7592.
7. 7. Ishigooka, M., Shimizu, T., Hiroya, K., and Hanato, M. (1992) Biochemistry 31, 1528-1531.
8. 8. Ellis, S. W., Hayhurst, G. P., Smith, G., Lightfoot, T., Wong, M. M. S., Simula, A. P., Ackland, M. J., Sternberg, M. J. E., Lennard, M. S., Tucker, G., and Wolf, C. R. (1995) J. Biol. Chem. 270, 29055-29058.
9. 9. Zhou, D., Korzekwa, K. R., Poulos, T., and Chen, S. (1992) J. Biol. Chem. 267, 762-768.
10. 10. Yeom, H., Sugar, S. G., Li, H., Poulos, T. L., and Fulco, A. J. (1995) Biochemistry 14733-14740.
11. 11. Gerber, N. C., and Sligar, S. G. (1992) J. Am. Chem. Soc. 114, 8742-8743.
12. 12. Gerber, N. C., and Sligar, S. G. (1994) J. Biol. Chem. 269, 4260-4266.
13. 13. Hasemann, C. A., Kurumbail, R. G., Boddupalli, S. S., Peterson, J. A., and Deisenhofer, J. (1995) Structure 2, 41-62.
14. 14. Shanthi, G., and Poulos, T. L. (1995) Biochemistry 34, 11221-11226.
15. 15. Sevrioukova, I. F., and Peterson, J. A. (1995) Arch. Biochem. Biophys. 317, 397-404.
16. 16. Aikens, J., and Sligar, S. G. (1994) J. Am. Chem. Soc. 116, 1143-1144.
17. 17. Raag, R., Martinis, S. A., Sligar, S. G., and Poulos, T. L. (1991) Biochemistry 30, 11420-11429.
18. 18. Wade, C. R. (1990) J. Comp. Aided Mol. Design 4, 199-204.
19. 19. Hiroya, K., Murakami, Y., Shimizu, T., Hanato, M., and Ortiz de Montellano, P. R. (1994) Arch. Biochem. Biophys. 310, 397-401.
20. 20. Cupp-Vickery, J. R., and Poulos, T. L. (1995) Nature Struct. Biol. 2, 144-153.
21. 21. Poulos, T. L., Finzel, B. C., and Howard, A. J. (1986) Biochemistry 25, 5314-5322.
22. 22. Hasemann, C. A., Ravichandran, K. G., Peterson, J. A., and Diesenhofer, J. (1994) J. Mol. Biol. 236, 1169-1185.
23. 23. Modi, S., Primrose, W. U., Boyle, J. M. B., Gibson, C. F., Lian, L.-Y., and Roberts, G. C. K. (1995) Biochemistry 34, 8982-8988.
24. 24. Shimada, H., Makino, R., Imai, M., Horiuchi, T., and Ishimura, Y. (1990) in International Symposia on Oxygenases and Oxygen Activation, pp. 133-136, Yamada Science Foundation.
25. 25. Imai, M., Shimada, H., Watanabe, Y., Matsushima-Hibiya, Y., Makino, R., Koga, H., Horiuchi, T., and Ishimura, Y. (1989) Proc. Natl. Acad. Sci. USA 86, 7823-7827.
26. 26. Kimata, Y., Shimada, H., Hirose, T., and Ishimura, Y. (1995) Biochem. Biophys. Res. Commun. 1, 96-102.
27. 27. Shimada, H., Watanabe, Y., Imai, M., Makino, R., Koga, H., Horiuchi, T., and Ishimura, Y. (1991) in Dioxygen Activation and Homogeneous Catalytic Oxidation (L. I. Simandi, Ed.), pp. 313-319, Elsevier Science, Amsterdam.
28. 28. Atkins, W., and Sligar, S. (1987) J. Am. Chem. Soc. 109, 3754-3760.
29. 29. Atkins, W., and Sligar, S. (1988) Biochemistry 27, 1610-1616.
30. 30. Gorsky, L., Koop, D., and Coon, M. (1984) J. Biol. Chem. 259, 6812-6817.
31. 31. Modi, S., Sutcliffe, M., Primrose, W., Lian, L., and Roberts, G. (1996) Nature Struct. Biol. 3, 414-417.
32. 32. Loida, P., and Sligar, S. (1993) Protein Eng. 6, 207-212.
33. 33. Loida, P., and Sligar, S. (1993) Biochemistry 32, 11530-11538.
34. 34. Paulson, M., and Ornstein, R. (1992) J. Comp. Aided Mol. Design 6, 449-460.