Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice

Neuropharmacology

Volumn 63, Issue 2, 2012, Pages 250-258

  Smith, Kiersten S ^a,b   Engin, Elif ^a,b   Meloni, Edward G ^a,b   Rudolph, Uwe ^a,b  

^a MCLEAN HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

subunit; Anxiety; Benzodiazepine; Conditioned fear; Fear potentiated startle; GABAA receptor

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA3; BENZODIAZEPINE; CHLORDIAZEPOXIDE; DIAZEPAM;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEAR; FEAR POTENTIATED STARTLE; GENOTYPE; LOCOMOTION; MALE; MAZE TEST; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; STARTLE REFLEX; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BEHAVIOR, ANIMAL; CHLORDIAZEPOXIDE; CONDITIONING (PSYCHOLOGY); DIAZEPAM; FEAR; MALE; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; PROTEIN SUBUNITS; RECEPTORS, GABA-A; STARTLE REACTION;

EID: 84861959996     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.03.001     Document Type: Article

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