SAR study on reactivators of ethyl-paraoxon inhibited acetylcholinesterase

Letters in Drug Design and Discovery

Volumn 9, Issue 6, 2012, Pages 587-594

  Holas, Ondrej ^a   Musilek, Kamil ^b,d   Horova, Anna ^c   Opletalova, Veronika ^a   Kuca, Kamil ^b,d  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b UNIVERSITY OF DEFENCE   (Czech Republic)

^c UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

^d UNIVERSITY OF HRADEC KRALOVE   (Czech Republic)

Author keywords

Acetylcholinesterase; Organophosphate; Oxime; Paraoxon; Reactivator; SAR

Indexed keywords

ACETYLCHOLINESTERASE; ASOXIME; CHOLINESTERASE REACTIVATOR; METHOXIME; OBIDOXIME; OXIME DERIVATIVE; PARAOXON; PRALIDOXIME; TRIMEDOXIME; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REACTIVATION; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

EID: 84861957447     PISSN: 15701808     EISSN: 1875628X     Source Type: Journal    
DOI: 10.2174/157018012800673083     Document Type: Article

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