Interference with xenobiotic metabolic activity by the commonly used vehicle solvents dimethylsulfoxide and methanol in zebrafish (Danio rerio) larvae but not Daphnia magna

Chemosphere

Volumn 88, Issue 8, 2012, Pages 912-917

  David, Rhiannon M ^a,d   Jones, Huw S ^a   Panter, Grace H ^b   Winter, Matthew J ^b   Hutchinson, Thomas H ^c   Kevin Chipman, J ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c CENTRE FOR ENVIRONMENT   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cytochromes P450; Daphnia magna; Solvents; Xenobiotic metabolism; Zebrafish

Indexed keywords

AQUATIC ORGANISMS; BIOCHEMISTRY; DETOXIFICATION; ENZYMES; GENE EXPRESSION; METABOLISM; METHANOL; POLYMERASE CHAIN REACTION; SOLVENTS; TOXICITY;

CYTOCHROMES P450; DAPHNIA MAGNA; DETOXIFICATION PROCESS; EFFECT OF SOLVENTS; LOW CONCENTRATIONS; METABOLIC ACTIVITY; XENOBIOTIC METABOLISM; ZEBRAFISH;

ORGANIC SOLVENTS;

AROCLOR 1254; CYTOCHROME P450; DIMETHYL SULFOXIDE; ETHOXYRESORUFIN; GLUCURONOSYLTRANSFERASE; METHANOL; XENOBIOTIC AGENT;

CRUSTACEAN; CYPRINID; CYTOCHROME; DETOXIFICATION; ENZYME ACTIVITY; FRESHWATER ENVIRONMENT; GENE EXPRESSION; LARVA; METABOLISM; METHANOL; ORGANIC POLLUTANT; POLLUTION EXPOSURE; POLYMERASE CHAIN REACTION; SOLVENT; TOXICITY TEST; XENOBIOTICS;

ARTICLE; CONTROLLED STUDY; DAPHNIA MAGNA; GENE EXPRESSION; IN VIVO STUDY; LARVA; NONHUMAN; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; ZEBRA FISH;

DANIO RERIO; DAPHNIA MAGNA;

EID: 84861949264     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2012.03.018     Document Type: Article

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