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Volumn 127, Issue 2, 2008, Pages 154-158

Plasma homocysteine levels & 677C→T methylenetetrahydrofolate reductase gene polymorphism in patiensts with coronary artery disease of different severity

Author keywords

Coronary artery disease; GENSINI score; Homocysteine; Methylenetetrahydrofolate reductase polymorphism

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYTOSINE; HOMOCYSTEINE; THYMINE;

EID: 46649094604     PISSN: 09715916     EISSN: 09715916     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (19)

References (27)
  • 1
    • 0037166647 scopus 로고    scopus 로고
    • Plasma total homocysteine and hospitalization for cardiovascular disease: The Hordaland Homocysteine Study
    • Nurk E, Tell GS, Vollset SE, Nygard O, Refsum H, Ueland PM. Plasma total homocysteine and hospitalization for cardiovascular disease: the Hordaland Homocysteine Study. Arch Intern Med 2002; 166: 1374-81.
    • (2002) Arch Intern Med , vol.166 , pp. 1374-1381
    • Nurk, E.1    Tell, G.S.2    Vollset, S.E.3    Nygard, O.4    Refsum, H.5    Ueland, P.M.6
  • 2
    • 1842331509 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for vascular disease: The European Concerted Action Project
    • Graham IM, Daly LE, Refsum H, Robinson K, Brattstrom LE, Ueland MP, et al Plasma homocysteine as a risk factor for vascular disease: the European Concerted Action Project. JAMA 1997; 277: 1775-81.
    • (1997) JAMA , vol.277 , pp. 1775-1781
    • Graham, I.M.1    Daly, L.E.2    Refsum, H.3    Robinson, K.4    Brattstrom, L.E.5    Ueland, M.P.6
  • 3
    • 0034808335 scopus 로고    scopus 로고
    • A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk
    • Lievers KJ, Boers GH, Verhoef P, den Heijer M, Kluijtmans LA, van der Put NM, et al. A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk. J Mol Med 2001; 79: 522-8.
    • (2001) J Mol Med , vol.79 , pp. 522-528
    • Lievers, K.J.1    Boers, G.H.2    Verhoef, P.3    den Heijer, M.4    Kluijtmans, L.A.5    van der Put, N.M.6
  • 4
    • 1242263957 scopus 로고    scopus 로고
    • Plasma homocysteine levels in patients with early coronary artery stenosis and high risk factors
    • Guo H, Lee JD, Ueda T, Shan J, Wang J. Plasma homocysteine levels in patients with early coronary artery stenosis and high risk factors. Jpn Heart J 2003; 44: 865-71.
    • (2003) Jpn Heart J , vol.44 , pp. 865-871
    • Guo, H.1    Lee, J.D.2    Ueda, T.3    Shan, J.4    Wang, J.5
  • 5
    • 0034511790 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and atherothrombosis
    • Cattaneo M. Hyperhomocysteinemia and atherothrombosis. Ann Med 2000; 32 (Suppl 1): 46-52.
    • (2000) Ann Med , vol.32 , Issue.SUPPL. 1 , pp. 46-52
    • Cattaneo, M.1
  • 6
    • 0034018386 scopus 로고    scopus 로고
    • Plasmahomocysteine and lipoprotein profile in patients with peripheral arterial occlusive disease
    • Rassoul F, Richter V, Janke C, Purschwitz K, Klötzer B, Geisel J, et al. Plasmahomocysteine and lipoprotein profile in patients with peripheral arterial occlusive disease. Angiology 2000; 51: 189-96.
    • (2000) Angiology , vol.51 , pp. 189-196
    • Rassoul, F.1    Richter, V.2    Janke, C.3    Purschwitz, K.4    Klötzer, B.5    Geisel, J.6
  • 7
    • 0037062676 scopus 로고    scopus 로고
    • Plasma homocysteine and parenteral myocardial infarction in young adults in Jerusalem
    • Kark JD, Sinnreich R, Rosenberg IH, Jacques PF, Selhub J. Plasma homocysteine and parenteral myocardial infarction in young adults in Jerusalem. Circulation 2000; 105: 2725-9.
    • (2000) Circulation , vol.105 , pp. 2725-2729
    • Kark, J.D.1    Sinnreich, R.2    Rosenberg, I.H.3    Jacques, P.F.4    Selhub, J.5
  • 8
    • 0033005234 scopus 로고    scopus 로고
    • Genetic analysis of the thermolabile variant of 5, 10-methylenetetrahydrofolate reductase as a risk factor for ischemic stroke
    • Harmon DL, Doyle RM, Meleady R, Dolye M, Shields DC, Barry R, et al. Genetic analysis of the thermolabile variant of 5, 10-methylenetetrahydrofolate reductase as a risk factor for ischemic stroke. Arterioscler Thromb Vasc Biol 1999; 19: 208-11.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 208-211
    • Harmon, D.L.1    Doyle, R.M.2    Meleady, R.3    Dolye, M.4    Shields, D.C.5    Barry, R.6
  • 9
    • 0034938880 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase genotypes and predisposition to atherothrombotic disease: Evidence that all three MTHFR C677T genotypes confer different levels of risk
    • Kluijtmans LA, Whitehead AS. Methylenetetrahydrofolate reductase genotypes and predisposition to atherothrombotic disease: evidence that all three MTHFR C677T genotypes confer different levels of risk. Eur Heart J 2001; 22: 294-9.
    • (2001) Eur Heart J , vol.22 , pp. 294-299
    • Kluijtmans, L.A.1    Whitehead, A.S.2
  • 10
    • 0042354109 scopus 로고    scopus 로고
    • Stimulatory effect of homocysteine on interleukin-8 expression in human endothelial cells
    • Geisel J, Jodden V, Obeid R, Knapp JP, Bodis M, Herrmann W. Stimulatory effect of homocysteine on interleukin-8 expression in human endothelial cells. Clin Chem Lab Med 2003; 41: 1045-8.
    • (2003) Clin Chem Lab Med , vol.41 , pp. 1045-1048
    • Geisel, J.1    Jodden, V.2    Obeid, R.3    Knapp, J.P.4    Bodis, M.5    Herrmann, W.6
  • 11
    • 0035810980 scopus 로고    scopus 로고
    • Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: Implications for vascular disease
    • Poddar R, Sivasubramanian N, DiBello PM, Robinson K, Jacobsen DW. Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: Implications for vascular disease. Circulation 2001; 103: 2717-23.
    • (2001) Circulation , vol.103 , pp. 2717-2723
    • Poddar, R.1    Sivasubramanian, N.2    DiBello, P.M.3    Robinson, K.4    Jacobsen, D.W.5
  • 12
    • 0036120318 scopus 로고    scopus 로고
    • Homocysteine upregulates vascular cell adhesion molecule-1 expression in cultured human aortic endothelial cells and enhances monocyte adhesion
    • Silverman MD, Tumuluri RJ, Davis M, Lopez G, Rosenbaum JT, Lelkes PI. Homocysteine upregulates vascular cell adhesion molecule-1 expression in cultured human aortic endothelial cells and enhances monocyte adhesion. Arterioscler Thromb Vasc Biol 2002; 22: 587-92.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 587-592
    • Silverman, M.D.1    Tumuluri, R.J.2    Davis, M.3    Lopez, G.4    Rosenbaum, J.T.5    Lelkes, P.I.6
  • 13
    • 0035969545 scopus 로고    scopus 로고
    • Decreased rate of coronary restenosis after lowering of plasma homocysteine levels
    • Schnyder G, Roffi M, Pin R, Flammer Y, Lange H, Eberli RF, et al. Decreased rate of coronary restenosis after lowering of plasma homocysteine levels. N Engl J Med 2001; 345: 1593-600.
    • (2001) N Engl J Med , vol.345 , pp. 1593-1600
    • Schnyder, G.1    Roffi, M.2    Pin, R.3    Flammer, Y.4    Lange, H.5    Eberli, R.F.6
  • 14
    • 0035002032 scopus 로고    scopus 로고
    • Total homocysteine, vitamin B12 and total antioxidant status in vegetarians
    • Herrmann W, Schorr H, Purschwitz K, Rassoul F, Richter V. Total homocysteine, vitamin B12 and total antioxidant status in vegetarians. Clin Chem 2001; 47: 1094-101.
    • (2001) Clin Chem , vol.47 , pp. 1094-1101
    • Herrmann, W.1    Schorr, H.2    Purschwitz, K.3    Rassoul, F.4    Richter, V.5
  • 15
    • 0023892344 scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase in patients with coronary artery disease
    • Kang SS, Wong PW, Zhou J. Thermolabile methylenetetrahydrofolate reductase in patients with coronary artery disease. Metabolism 1988; 37: 611-3.
    • (1988) Metabolism , vol.37 , pp. 611-613
    • Kang, S.S.1    Wong, P.W.2    Zhou, J.3
  • 16
    • 0029049553 scopus 로고
    • A candidate genetic risk factors for vascular disease: A common mutation in methylenetetrahydrofolate reductase: Isolation of cDNA, mapping and mutation identification
    • Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthew RG, et al. A candidate genetic risk factors for vascular disease: A common mutation in methylenetetrahydrofolate reductase: Isolation of cDNA, mapping and mutation identification. Nat Genet 1995; 10: 110-3.
    • (1995) Nat Genet , vol.10 , pp. 110-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3    Goyette, P.4    Sheppard, C.A.5    Matthew, R.G.6
  • 17
    • 0030934392 scopus 로고    scopus 로고
    • Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease
    • Christensen B, Frosst P, Lussier-Cacan S, Selhub J, Goyette P, Rosenblatt DS, et al. Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease. Arteriosler Thromb Vasc Biol 1997; 17: 569-73.
    • (1997) Arteriosler Thromb Vasc Biol , vol.17 , pp. 569-573
    • Christensen, B.1    Frosst, P.2    Lussier-Cacan, S.3    Selhub, J.4    Goyette, P.5    Rosenblatt, D.S.6
  • 18
    • 0020701346 scopus 로고
    • A more meaningful scoring system for determining the severity of coronary heart disease
    • Gensini GG. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol 1983; 51: 606.
    • (1983) Am J Cardiol , vol.51 , pp. 606
    • Gensini, G.G.1
  • 19
    • 0023628783 scopus 로고
    • Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection
    • Araki A, Sako Y. Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr 1987; 422: 43-52.
    • (1987) J Chromatogr , vol.422 , pp. 43-52
    • Araki, A.1    Sako, Y.2
  • 20
    • 2342485635 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms, plasma homocysteine, folate, vitamin B12 levels and the extent of coronary artery disease
    • Kolling K, Ndrepepa G, Koch W, Braun S, Mehilli J, Schomig A, et al. Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms, plasma homocysteine, folate, vitamin B12 levels and the extent of coronary artery disease. Am J Cardiol 2004; 93: 1201-6.
    • (2004) Am J Cardiol , vol.93 , pp. 1201-1206
    • Kolling, K.1    Ndrepepa, G.2    Koch, W.3    Braun, S.4    Mehilli, J.5    Schomig, A.6
  • 21
    • 0033623528 scopus 로고    scopus 로고
    • Correlation of homocysteine levels with the extent of coronary atherosclerosis in patients with low cardiovascular risk profiles
    • Tsai WC, Li YH, Tsai LM, Chao TH, Lin LJ, Chen TY, et al. Correlation of homocysteine levels with the extent of coronary atherosclerosis in patients with low cardiovascular risk profiles. Am J Cardiol 2000; 85: 49-52.
    • (2000) Am J Cardiol , vol.85 , pp. 49-52
    • Tsai, W.C.1    Li, Y.H.2    Tsai, L.M.3    Chao, T.H.4    Lin, L.J.5    Chen, T.Y.6
  • 23
    • 0033118493 scopus 로고    scopus 로고
    • Moderate hyperhomocyst(e)inemia is associated with the presence of coronary artery disease and the severity of coronary atherosclerosis in Koreans
    • Yoo HJ, Park JE, Hong KP, Lee SH, Kim DK, Lee WR, et al. Moderate hyperhomocyst(e)inemia is associated with the presence of coronary artery disease and the severity of coronary atherosclerosis in Koreans. Thromb Res 1999; 94: 45-52.
    • (1999) Thromb Res , vol.94 , pp. 45-52
    • Yoo, H.J.1    Park, J.E.2    Hong, K.P.3    Lee, S.H.4    Kim, D.K.5    Lee, W.R.6
  • 24
    • 0038167784 scopus 로고    scopus 로고
    • The Effects of hyperhomocysteinemia on the presence, extent, and severity of coronary artery disease
    • Bozkurt A, Toyaksi H, Acartürk E, Tuli A, Cayli M. The Effects of hyperhomocysteinemia on the presence, extent, and severity of coronary artery disease. Jpn Heart J 2003; 44: 357-68.
    • (2003) Jpn Heart J , vol.44 , pp. 357-368
    • Bozkurt, A.1    Toyaksi, H.2    Acartürk, E.3    Tuli, A.4    Cayli, M.5
  • 25
    • 2442629250 scopus 로고    scopus 로고
    • Plasma homocysteine levels and the angiographic extent of coronary artery disease
    • Bozkurt E, Keles S, Acikel M, Islek M, Atesal S. Plasma homocysteine levels and the angiographic extent of coronary artery disease. Angiology 2004; 55: 265-70.
    • (2004) Angiology , vol.55 , pp. 265-270
    • Bozkurt, E.1    Keles, S.2    Acikel, M.3    Islek, M.4    Atesal, S.5
  • 26
    • 17844365299 scopus 로고    scopus 로고
    • Plasma homocysteine levels and the left ventricular systolic function in coronary artery disease patients
    • Bokhari SW, Bokhari ZW, Zell JA, Lee DW, Faxon DP. Plasma homocysteine levels and the left ventricular systolic function in coronary artery disease patients. Coron Artery Dis 2005; 16: 153-61.
    • (2005) Coron Artery Dis , vol.16 , pp. 153-161
    • Bokhari, S.W.1    Bokhari, Z.W.2    Zell, J.A.3    Lee, D.W.4    Faxon, D.P.5
  • 27
    • 0032941872 scopus 로고    scopus 로고
    • TT genotype of the methylenetetrahydrofolate reductase C677T gene polymorphism is associated with the extent of coronary atherosclerosis in patients at high risk for coronary artery disease
    • Gardemann A, Weidemann H, Philipp M, Katz N, Tillmanns H, Hehrlein FW, et al. TT genotype of the methylenetetrahydrofolate reductase C677T gene polymorphism is associated with the extent of coronary atherosclerosis in patients at high risk for coronary artery disease. Eur Heart J 1999; 20: 584-92.
    • (1999) Eur Heart J , vol.20 , pp. 584-592
    • Gardemann, A.1    Weidemann, H.2    Philipp, M.3    Katz, N.4    Tillmanns, H.5    Hehrlein, F.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.