-
1
-
-
1842331509
-
Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project
-
Graham IM, Daly LE, Refsum HM, Robinson K, Brattstrom LE, Ueland PM et al. Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. JAMA. 1997;277:1775-81.
-
(1997)
JAMA
, vol.277
, pp. 1775-81
-
-
Graham, I.M.1
Daly, L.E.2
Refsum, H.M.3
Robinson, K.4
Brattstrom, L.E.5
Ueland, P.M.6
-
2
-
-
0032420184
-
Recent data are not in conflict with homocysteine as a cardiovascular risk factor
-
Refsum H, Ueland PM. Recent data are not in conflict with homocysteine as a cardiovascular risk factor. Curr Opin Lipidol. 1998;9:533-9.
-
(1998)
Curr Opin Lipidol
, vol.9
, pp. 533-9
-
-
Refsum, H.1
Ueland, P.M.2
-
4
-
-
0029655724
-
Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
-
Kluijtmans LA, van den Heuvel LP, Boers GH, Frosst P, Stevens EM, van Oost BA et al. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet. 1996;58: 35-41.
-
(1996)
Am J Hum Genet.
, vol.58
, pp. 35-41
-
-
Kluijtmans, L.A.1
van den Heuvel, L.P.2
Boers, G.H.3
Frosst, P.4
Stevens, E.M.5
van Oost, B.A.6
-
5
-
-
0030897112
-
Genetic polymorphism of 5 10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
-
Morita H, Taguchi J, Kurihara H, Kitaoka M, Kaneda H, Kurihara Y et al. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation. 1997;95:2032-6.
-
(1997)
Circulation
, vol.95
, pp. 2032-6
-
-
Morita, H.1
Taguchi, J.2
Kurihara, H.3
Kitaoka, M.4
Kaneda, H.5
Kurihara, Y.6
-
6
-
-
0023696435
-
Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase
-
Kang SS, Zhou J, Wong PW, Kowalisyn J, Strokosch G. Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet. 1998;43:414-21.
-
(1998)
Am J Hum Genet
, vol.43
, pp. 414-21
-
-
Kang, S.S.1
Zhou, J.2
Wong, P.W.3
Kowalisyn, J.4
Strokosch, G.5
-
7
-
-
0030826587
-
Thermolabile methylenetetrahydrofolate reductase in coronary artery disease
-
Kluijtmans LA, Kastelein JJP, Lindemans J, Boers GH J, Hell SG, Bruschke AVG et al. Thermolabile methylenetetrahydrofolate reductase in coronary artery disease. Circulation. 1997;96:2573-7.
-
(1997)
Circulation
, vol.96
, pp. 2573-7
-
-
Kluijtmans, L.A.1
Kastelein, J.J.P.2
Lindemans, J.3
Boers, G.H.J.4
Hell, S.G.5
Bruschke, A.V.G.6
-
8
-
-
2142819381
-
High prevalence of hyperhomocysteinemia related to folate deficiency and the 677C-->T mutation of the gene encoding methylenetetrahydrofolate reductase in coastal West Africa
-
Amouzou EK, Chabi NW, Adjalla CE, Rodriguez-Gueant RM, Feillet F, Villaume C, Sanni A, Gueant JL. High prevalence of hyperhomocysteinemia related to folate deficiency and the 677C-->T mutation of the gene encoding methylenetetrahydrofolate reductase in coastal West Africa. Am J Clin Nutr. 2004;79:619-24.
-
(2004)
Am J Clin Nutr
, vol.79
, pp. 619-24
-
-
Amouzou, E.K.1
Chabi, N.W.2
Adjalla, C.E.3
Rodriguez-Gueant, R.M.4
Feillet, F.5
Villaume, C.6
Sanni, A.7
Gueant, J.L.8
-
9
-
-
22044432413
-
Dose-related association of MTHFR 677T allele with risk of ischemic stroke: evidence from a cumulative meta-analysis
-
Cronin S, Furie KL, Kelly PJ. Dose-related association of MTHFR 677T allele with risk of ischemic stroke: evidence from a cumulative meta-analysis. Stroke. 2005;36:1581-7.
-
(2005)
Stroke
, vol.36
, pp. 1581-7
-
-
Cronin, S.1
Furie, K.L.2
Kelly, P.J.3
-
10
-
-
0032497941
-
Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis
-
Brattström L, Wilcken DE, Öhrvik J, Brudin L. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. Circulation. 1998;98:2520-6.
-
(1998)
Circulation
, vol.98
, pp. 2520-6
-
-
Brattström, L.1
Wilcken, D.E.2
Öhrvik, J.3
Brudin, L.4
-
11
-
-
0023628783
-
Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection
-
Araki A, Sako Y. Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr. 1987; 422:43-52.
-
(1987)
J Chromatogr
, vol.422
, pp. 43-52
-
-
Araki, A.1
Sako, Y.2
-
12
-
-
0032965761
-
A simple, sensitive and reproducible assay for pyridoxal 5'-phosphate and 4-pyridoxic acid in human plasma
-
Bates CJ, Pentieva KD, Matthews N, Macdonald A. A simple, sensitive and reproducible assay for pyridoxal 5'-phosphate and 4-pyridoxic acid in human plasma. Clin Chim Acta. 1999;280:101-11.
-
(1999)
Clin Chim Acta
, vol.280
, pp. 101-11
-
-
Bates, C.J.1
Pentieva, K.D.2
Matthews, N.3
Macdonald, A.4
-
13
-
-
4644332790
-
Measurement of C-reactive protein: two high sensitivity methods compared
-
Dominici R, Luraschi P, Franzini C. Measurement of C-reactive protein: two high sensitivity methods compared. J Clin Lab Anal. 2004;18:280-4.
-
(2004)
J Clin Lab Anal
, vol.18
, pp. 280-4
-
-
Dominici, R.1
Luraschi, P.2
Franzini, C.3
-
14
-
-
0030859681
-
A mutation in the methylenetetrahydrofolate reductase gene is not associated with increase risk for coronary artery disease or myocardial infarction
-
Anderson JL, King GJ, Thomson J, Todd M, Bair TL, Muhlestein JB, Carlquist JF. A mutation in the methylenetetrahydrofolate reductase gene is not associated with increase risk for coronary artery disease or myocardial infarction. J Am Coll Cardiol. 1997;30:1206-11.
-
(1997)
J Am Coll Cardiol
, vol.30
, pp. 1206-11
-
-
Anderson, J.L.1
King, G.J.2
Thomson, J.3
Todd, M.4
Bair, T.L.5
Muhlestein, J.B.6
Carlquist, J.F.7
-
15
-
-
0030880665
-
A common polymorphism in the methylenetetrahydrofolate reductase gene, homocysteine, and ischemic cerebrovascular disease
-
Markus HS, Ali N, Swaminathan R, Sankaralingam A, Molloy J, Powell J. A common polymorphism in the methylenetetrahydrofolate reductase gene, homocysteine, and ischemic cerebrovascular disease. Stroke. 1997;28:1739-43.
-
(1997)
Stroke
, vol.28
, pp. 1739-43
-
-
Markus, H.S.1
Ali, N.2
Swaminathan, R.3
Sankaralingam, A.4
Molloy, J.5
Powell, J.6
-
16
-
-
0030027668
-
Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
-
Jacques PF, Bostom AG, Williams RR, Ellison R C, Eckfeldt JH, Rosenberg IH, Selhub J, Rozen R. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation. 1996; 93:7-9.
-
(1996)
Circulation
, vol.93
, pp. 7-9
-
-
Jacques, P.F.1
Bostom, A.G.2
Williams, R.R.3
Ellison, R.C.4
Eckfeldt, J.H.5
Rosenberg, I.H.6
Selhub, J.7
Rozen, R.8
-
19
-
-
0037214152
-
EC Concerted Action Project: Homocysteine and Vascular Disease. Thermolabile methylenetetrahydrofolate reductase, homocysteine, and cardiovascular disease risk: the European Concerted Action Project
-
Meleady R, Ueland PM, Blom H, Whitehead AS, Refsum H, Daly LE et al. EC Concerted Action Project: Homocysteine and Vascular Disease. Thermolabile methylenetetrahydrofolate reductase, homocysteine, and cardiovascular disease risk: the European Concerted Action Project. Am J Clin Nutr. 2003;77:63-70.
-
(2003)
Am J Clin Nutr
, vol.77
, pp. 63-70
-
-
Meleady, R.1
Ueland, P.M.2
Blom, H.3
Whitehead, A.S.4
Refsum, H.5
Daly, L.E.6
-
20
-
-
0031961002
-
Worldwide distribution of a common methylenetetrahydrofolate reductase mutation
-
Schneider JA, Rees DC, Liu YT, Clegg JB. Worldwide distribution of a common methylenetetrahydrofolate reductase mutation. Am J Hum Genet. 1998;62:1258-60.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1258-60
-
-
Schneider, J.A.1
Rees, D.C.2
Liu, Y.T.3
Clegg, J.B.4
-
21
-
-
0037163849
-
MTHFR 677C → T polymorphism and risk of coronary heart disease: a meta-analysis
-
Klerk M, Verhoef P, Clarke P, Blom HJ, Kok FJ, Schouten EG et al. MTHFR 677C → T polymorphism and risk of coronary heart disease: a meta-analysis. JAMA. 2002;288: 2023-31.
-
(2002)
JAMA
, vol.288
, pp. 2023-31
-
-
Klerk, M.1
Verhoef, P.2
Clarke, P.3
Blom, H.J.4
Kok, F.J.5
Schouten, E.G.6
-
22
-
-
0029806746
-
Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
-
Ma J, Stampfer MJ, Hennekens CH, Frosst P, Selhub J, Horsford J, Malinow MR, Willett WC, Rozen R. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation. 1996;94: 2410-6
-
(1996)
Circulation
, vol.94
, pp. 2410-6
-
-
Ma, J.1
Stampfer, M.J.2
Hennekens, C.H.3
Frosst, P.4
Selhub, J.5
Horsford, J.6
Malinow, M.R.7
Willett, W.C.8
Rozen, R.9
-
23
-
-
0032714729
-
The graded effect of hyperhomocysteinemia on the severity and extent of coronary atherosclerosis
-
Chao CL, Tsai HH, Lee CM, Hsu SM, Kao JT, Chien KL, Sung FC, Lee YT. The graded effect of hyperhomocysteinemia on the severity and extent of coronary atherosclerosis. Atherosclerosis. 1999;147:379-86.
-
(1999)
Atherosclerosis
, vol.147
, pp. 379-86
-
-
Chao, C.L.1
Tsai, H.H.2
Lee, C.M.3
Hsu, S.M.4
Kao, J.T.5
Chien, K.L.6
Sung, F.C.7
Lee, Y.T.8
-
24
-
-
0031757073
-
Genotyping method for methylenetetrahydrofolate reductase (C677T thermolabile variant) using heteroduplex technology
-
Clark ZE, Bowen DJ, Whatley SD, Bellamy MF, Collins PW, McDowell IF. Genotyping method for methylenetetrahydrofolate reductase (C677T thermolabile variant) using heteroduplex technology. Clin Chem. 1998;44:2360-2.
-
(1998)
Clin Chem
, vol.44
, pp. 2360-2
-
-
Clark, Z.E.1
Bowen, D.J.2
Whatley, S.D.3
Bellamy, M.F.4
Collins, P.W.5
McDowell, I.F.6
-
25
-
-
2342528999
-
The 5 10-methylenetetrahydrofolate reductase C677T polymorphism interacts with smoking to increase homocysteine
-
Brown KS, Kluijtmans LA, Young IS, Murray L, McMaster D, Woodside JV et al. The 5,10-methylenetetrahydrofolate reductase C677T polymorphism interacts with smoking to increase homocysteine. Atherosclerosis. 2004;174:315-22.
-
(2004)
Atherosclerosis
, vol.174
, pp. 315-22
-
-
Brown, K.S.1
Kluijtmans, L.A.2
Young, I.S.3
Murray, L.4
McMaster, D.5
Woodside, J.V.6
-
26
-
-
0030897112
-
Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease
-
Morita H, Taguchi J, Kurihara H, Kitaoka M, Kaneda H, Kurihara Y et al. Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation. 1997;95:2032-6.
-
(1997)
Circulation
, vol.95
, pp. 2032-6
-
-
Morita, H.1
Taguchi, J.2
Kurihara, H.3
Kitaoka, M.4
Kaneda, H.5
Kurihara, Y.6
-
28
-
-
0042919553
-
Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a multicenter case-control study in China
-
Li Z, Sun L, Zhang H, Liao Y, Wang D, Zhao B et al. Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a multicenter case-control study in China. Stroke. 2003;34:2085-90.
-
(2003)
Stroke
, vol.34
, pp. 2085-90
-
-
Li, Z.1
Sun, L.2
Zhang, H.3
Liao, Y.4
Wang, D.5
Zhao, B.6
-
30
-
-
0022471265
-
Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease
-
Kang SS, Wong PWK, Cook HY, Norusis M, Messer JV. Protein-bound homocyst(e)ine. A possible risk factor for coronary artery disease. J Clin Invest. 1986;77:1482-6.
-
(1986)
J Clin Invest
, vol.77
, pp. 1482-6
-
-
Kang, S.S.1
Wong, P.W.K.2
Cook, H.Y.3
Norusis, M.4
Messer, J.V.5
-
31
-
-
0028284362
-
Rapid HPLC determination of total homocysteine and other thiols in serum and plasma: sex differences and correlation with cobalamin and folate concentrations in healthy subjects
-
Jacobsen DW, Gatautis VJ, Green R, Robinson K, Savon SR, Secic M, Ji J, Otto JM, Taylor LM Jr. Rapid HPLC determination of total homocysteine and other thiols in serum and plasma: sex differences and correlation with cobalamin and folate concentrations in healthy subjects. Clin Chem. 1994;40:873-81.
-
(1994)
Clin Chem
, vol.40
, pp. 873-81
-
-
Jacobsen, D.W.1
Gatautis, V.J.2
Green, R.3
Robinson, K.4
Savon, S.R.5
Secic, M.6
Ji, J.7
Otto, J.M.8
Taylor L.M., Jr.9
-
32
-
-
0038721954
-
Homocysteine and risk of coronary artery disease: Folate is the important determinant of plasma homocysteine concentration
-
Lee BJ, Lin PT, Liaw YP, Chang SJ, Cheng CH, Huang YC. Homocysteine and risk of coronary artery disease: Folate is the important determinant of plasma homocysteine concentration. Nutrition. 2003;19:577-83.
-
(2003)
Nutrition
, vol.19
, pp. 577-83
-
-
Lee, B.J.1
Lin, P.T.2
Liaw, Y.P.3
Chang, S.J.4
Cheng, C.H.5
Huang, Y.C.6
-
33
-
-
0038648465
-
Secondary prevention with folic acid: effects on clinical outcomes
-
Liem A, Reynierse-Buitenwerf GH, Zwinderman AH, Jukema JW, van Veldhuisen DJ. Secondary prevention with folic acid: effects on clinical outcomes. J Am College Cardiol. 2003;41:2105-13.
-
(2003)
J Am College Cardiol
, vol.41
, pp. 2105-13
-
-
Liem, A.1
Reynierse-Buitenwerf, G.H.2
Zwinderman, A.H.3
Jukema, J.W.4
van Veldhuisen, D.J.5
-
34
-
-
33645796222
-
Homocysteine lowering and cardiovascular events after acute myocardial infarction
-
Bǿnaa KH, Njǿlstad I, Ueland PM, Schirmer H, Tverdal A, Steigen T et al. Homocysteine lowering and cardiovascular events after acute myocardial infarction. N Engl J Med. 2006;354:1578-88.
-
(2006)
N Engl J Med
, vol.354
, pp. 1578-88
-
-
Bǿnaa, K.H.1
Njǿlstad, I.2
Ueland, P.M.3
Schirmer, H.4
Tverdal, A.5
Steigen, T.6
-
35
-
-
33645753544
-
The Heart Outcomes Prevention Evaluation (HOPE) 2 investigators. Homocysteine lowering with folic acid and B vitamins in vascular disease
-
The Heart Outcomes Prevention Evaluation (HOPE) 2 investigators. Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med. 2006;354:1567-77.
-
(2006)
N Engl J Med
, vol.354
, pp. 1567-77
-
-
-
36
-
-
0029963687
-
Will an increased dietary folate intake reduce the incidence of cardiovascular disease?
-
Ubbink JB, Becker PJ, Vermaak WJH. Will an increased dietary folate intake reduce the incidence of cardiovascular disease? Nutr Rev. 1996;54:213-6.
-
(1996)
Nutr Rev
, vol.54
, pp. 213-6
-
-
Ubbink, J.B.1
Becker, P.J.2
Vermaak, W.J.H.3
|