Dissociation of recombinant prion protein fibrils into short protofilaments: Implications for the endocytic pathway and involvement of the N-terminal domain

Biochemistry

Volumn 51, Issue 22, 2012, Pages 4600-4608

  Qi, Xu ^a   Moore, Roger A ^b   McGuirl, Michele A ^a  

^a UNIVERSITY OF MONTANA   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID FIBRIL; BIOPHYSICAL CHARACTERISTICS; CHARGE REPULSION; DISSOCIATION PROCESS; ENDOCYTIC PATHWAYS; LATE ENDOSOMES; N-TERMINAL DOMAINS; PRION PROTEIN; PRION PROTEIN FIBRILS; PROTOFILAMENTS;

DISSOCIATION; GLYCOPROTEINS; PH EFFECTS;

RECOMBINANT PROTEINS;

PRION PROTEIN; RECOMBINANT PRION PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISSOCIATION; ENDOCYTOSIS; ENDOSOME; FIBER; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON TRANSPORT;

AMYLOID; ANIMALS; CIRCULAR DICHROISM; CRICETINAE; ENDOCYTOSIS; HYDROGEN-ION CONCENTRATION; MESOCRICETUS; PRIONS; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84861892097     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300201e     Document Type: Article

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