LSK derived LSK- cells have a high apoptotic rate related to survival regulation of hematopoietic and leukemic stem cells

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Peng, Cong ^a,c   Chen, Yaoyu ^a,d   Shan, Yi ^a   Zhang, Haojian ^a   Guo, Zhiru ^a   Li, Dongguang ^b   Li, Shaoguang ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b EDITH COWAN UNIVERSITY   (Australia)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; FLUOROURACIL; HEAT SHOCK PROTEIN 90; IMATINIB; ARACHIDONATE 5 LIPOXYGENASE; CD150 ANTIGEN; CELL SURFACE RECEPTOR; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR; LEUKOCYTE ANTIGEN; LY ANTIGEN; LY6A PROTEIN, MOUSE; LYN PROTEIN-TYROSINE KINASE; MEMBRANE PROTEIN; PIPERAZINE DERIVATIVE; PROTEIN KINASE LYN; PROTEIN TYROSINE KINASE; PYRIMIDINE DERIVATIVE; STEM CELL FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL POPULATION; CELL SURVIVAL; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DOWNSTREAM PROCESSING; GENE DELETION; HEMATOPOIETIC STEM CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; ANIMAL; CANCER STEM CELL; CELL LINEAGE; DRUG EFFECT; GAMMA RADIATION; METABOLISM; PATHOLOGY; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; TIME;

MUS;

ANIMALS; ANTIGENS, CD; ANTIGENS, LY; APOPTOSIS; ARACHIDONATE 5-LIPOXYGENASE; CELL LINEAGE; CELL SURVIVAL; FLUOROURACIL; FUSION PROTEINS, BCR-ABL; GAMMA RAYS; HEMATOPOIETIC STEM CELLS; HSP90 HEAT-SHOCK PROTEINS; INTERFERON REGULATORY FACTORS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MEMBRANE PROTEINS; MICE; NEOPLASTIC STEM CELLS; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-KIT; PYRIMIDINES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TIME FACTORS;

EID: 84861872414     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038614     Document Type: Article

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