메뉴 건너뛰기




Volumn 122, Issue 6, 2012, Pages 2239-2251

Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR-2 signaling

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR 2;

EID: 84861820916     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI58147     Document Type: Article
Times cited : (37)

References (58)
  • 1
    • 0031461206 scopus 로고    scopus 로고
    • Epithelial cells as sensors for microbial infection
    • Kagnoff MF, Eckmann L. Epithelial cells as sensors for microbial infection. J Clin Invest. 1997; 100(1):6-10. (Pubitemid 27311236)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.1 , pp. 6-10
    • Kagnoff, M.F.1    Eckman, L.2
  • 3
    • 2142813761 scopus 로고    scopus 로고
    • A porous defense: The leaky epithelial barrier in intestinal disease
    • DOI 10.1038/labinvest.3700050
    • Clayburgh DR, Shen L, Turner JR. A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest. 2004;84(3):282-291. (Pubitemid 41656483)
    • (2004) Laboratory Investigation , vol.84 , Issue.3 , pp. 282-291
    • Clayburgh, D.R.1    Shen, L.2    Turner, J.R.3
  • 4
    • 79956063855 scopus 로고    scopus 로고
    • Peyer's Patches: The immune sensors of the intestine
    • Jung C, Hugot JP, Barreau F. Peyer's Patches: The immune sensors of the intestine. Int J Inflam. 2010; 2010:823710.
    • (2010) Int J Inflam , vol.2010 , pp. 823710
    • Jung, C.1    Hugot, J.P.2    Barreau, F.3
  • 5
    • 58649090901 scopus 로고    scopus 로고
    • Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis
    • Su L, et al. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology. 2009;136(2):551-563.
    • (2009) Gastroenterology , vol.136 , Issue.2 , pp. 551-563
    • Su, L.1
  • 8
    • 13244298599 scopus 로고    scopus 로고
    • Interferon-gamam and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression
    • Wang F, Graham WV, Wang Y, Witkowski ED, Schwarz BT, Turner JR. Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. Am J Pathol. 2005;166(2):409-419. (Pubitemid 40189038)
    • (2005) American Journal of Pathology , vol.166 , Issue.2 , pp. 409-419
    • Wang, F.1    Graham, W.V.2    Wang, Y.3    Witkowski, E.D.4    Schwarz, B.T.5    Turner, J.R.6
  • 9
    • 45949086355 scopus 로고    scopus 로고
    • Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability
    • Al-Sadi R, Ye D, Dokladny K, Ma TY. Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. J Immunol. 2008; 180(8):5653-5661.
    • (2008) J Immunol , vol.180 , Issue.8 , pp. 5653-5661
    • Al-Sadi, R.1    Ye, D.2    Dokladny, K.3    Ma, T.Y.4
  • 10
    • 33947631511 scopus 로고    scopus 로고
    • IL-1beta causes an increase in intestinal epithelial tight junction permeability
    • Al-Sadi RM, Ma TY. IL-1beta causes an increase in intestinal epithelial tight junction permeability. J Immunol. 2007;178(7):4641-4649. (Pubitemid 46492417)
    • (2007) Journal of Immunology , vol.178 , Issue.7 , pp. 4641-4649
    • Al-Sadi, R.M.1    Ma, T.Y.2
  • 11
    • 22644444207 scopus 로고    scopus 로고
    • Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2
    • DOI 10.1136/gut.2004.062794
    • Cario E. Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2. Gut. 2005;54(8):1182-1193. (Pubitemid 41025918)
    • (2005) Gut , vol.54 , Issue.8 , pp. 1182-1193
    • Cario, E.1
  • 14
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
    • DOI 10.1016/S1074-7613(00)80119-3
    • Takeuchi O, et al. Differential roles of TLR2 and TLR4 in recognition of gram-negative and grampositive bacterial cell wall components. Immunity. 1999;11(4):443-451. (Pubitemid 29504199)
    • (1999) Immunity , vol.11 , Issue.4 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5    Ogawa, T.6    Takeda, K.7    Akira, S.8
  • 15
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • DOI 10.1016/j.cell.2004.07.002, PII S0092867404006610
    • Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell. 2004;118(2):229-241. (Pubitemid 38962578)
    • (2004) Cell , vol.118 , Issue.2 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 16
    • 33646037701 scopus 로고    scopus 로고
    • TLRs regulate the gatekeeping functions of the intestinal follicle-associated epithelium
    • Chabot S, Wagner JS, Farrant S, Neutra MR. TLRs regulate the gatekeeping functions of the intestinal follicle-associated epithelium. J Immunol. 2006; 176(7):4275-4283. (Pubitemid 44264407)
    • (2006) Journal of Immunology , vol.176 , Issue.7 , pp. 4275-4283
    • Chabot, S.1    Wagner, J.S.2    Farrant, S.3    Neutra, M.R.4
  • 17
    • 4444243168 scopus 로고    scopus 로고
    • Expression and distribution of beta1 integrins in in vitro-induced M cells: Implications for Yersinia adhesion to Peyer's patch epithelium
    • DOI 10.1111/j.1462-5822.2004.00391.x
    • Hamzaoui N, Kerneis S, Caliot E, Pringault E. Expression and distribution of beta1 integrins in in vitro-induced M cells: implications for Yersinia adhesion to Peyer's patch epithelium. Cell Microbiol. 2004;6(9):817-828. (Pubitemid 39162624)
    • (2004) Cellular Microbiology , vol.6 , Issue.9 , pp. 817-828
    • Hamzaoui, N.1    Kerneis, S.2    Caliot, E.3    Pringault, E.4
  • 18
    • 1342344906 scopus 로고    scopus 로고
    • Characterization of Oral Yersinia enterocolitica Infection in Three Different Strains of Inbred Mice
    • DOI 10.1128/IAI.72.3.1645-1656.2004
    • Handley SA, Dube PH, Revell PA, Miller VL. Characterization of oral Yersinia enterocolitica infection in three different strains of inbred mice. Infect Immun. 2004;72(3):1645-1656. (Pubitemid 38263788)
    • (2004) Infection and Immunity , vol.72 , Issue.3 , pp. 1645-1656
    • Handley, S.A.1    Dube, P.H.2    Revell, P.A.3    Miller, V.L.4
  • 19
    • 0035055291 scopus 로고    scopus 로고
    • Identification of attenuated Yersinia pseudotuberculosis strains and characterization of an orogastric infection in BALB/c mice on day 5 postinfection by signature-tagged mutagenesis
    • DOI 10.1128/IAI.67.5.2779-2787.2001
    • Mecsas J, Bilis I, Falkow S. Identification of attenuated Yersinia pseudotuberculosis strains and characterization of an orogastric infection in BALB/c mice on day 5 postinfection by signature-tagged mutagenesis. Infect Immun. 2001;69(5):2779-2787. (Pubitemid 32332165)
    • (2001) Infection and Immunity , vol.69 , Issue.5 , pp. 2779-2787
    • Mecsas, J.1    Bilis, I.2    Falkow, S.3
  • 20
    • 0028807421 scopus 로고
    • Pathogenesis of defined invasion mutants of Yersinia enterocolitica in a BALB/c mouse model of infection
    • Pepe JC, Wachtel MR, Wagar E, Miller VL. Pathogenesis of defined invasion mutants of Yersinia enterocolitica in a BALB/c mouse model of infection. Infect Immun. 1995;63(12):4837-4848.
    • (1995) Infect Immun , vol.63 , Issue.12 , pp. 4837-4848
    • Pepe, J.C.1    Wachtel, M.R.2    Wagar, E.3    Miller, V.L.4
  • 21
    • 66649092877 scopus 로고    scopus 로고
    • Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis
    • Dessein R, et al. Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis. Gut. 2009; 58(6):771-776.
    • (2009) Gut , vol.58 , Issue.6 , pp. 771-776
    • Dessein, R.1
  • 22
    • 34447286255 scopus 로고    scopus 로고
    • Growth of Yersinia pseudotuberculosis in mice occurs independently of toll-like receptor 2 expression and induction of interleukin-10
    • DOI 10.1128/IAI.01497-06
    • Auerbuch V, Isberg RR. Growth of Yersinia pseudotuberculosis in mice occurs independently of Toll-like receptor 2 expression and induction of interleukin-10. Infect Immun. 2007;75(7):3561-3570. (Pubitemid 47040959)
    • (2007) Infection and Immunity , vol.75 , Issue.7 , pp. 3561-3570
    • Auerbuch, V.1    Isberg, R.R.2
  • 25
    • 0022506170 scopus 로고
    • Acute yersinia infections in man increase intestinal permeability for low-molecular weight polyethylene glycols (PEG 400)
    • Serrander R, Magnusson KE, Kihlstrom E, Sundqvist T. Acute yersinia infections in man increase intestinal permeability for low-molecular weight polyethylene glycols (PEG 400). Scand J Infect Dis. 1986; 18(5):409-413. (Pubitemid 16017367)
    • (1986) Scandinavian Journal of Infectious Diseases , vol.18 , Issue.5 , pp. 409-413
    • Serrander, R.1    Magnusson, K.-E.2    Kihlstrom, E.3    Sundqvist, T.4
  • 26
    • 0033855909 scopus 로고    scopus 로고
    • Apically exposed, tight junction-associated beta1-integrins allow binding and YopE-mediated perturbation of epithelial barriers by wild-type Yersinia bacteria
    • Tafazoli F, Holmstrom A, Forsberg A, Magnusson KE. Apically exposed, tight junction-associated beta1-integrins allow binding and YopE-mediated perturbation of epithelial barriers by wild-type Yersinia bacteria. Infect Immun. 2000;68(9):5335-5343.
    • (2000) Infect Immun , vol.68 , Issue.9 , pp. 5335-5343
    • Tafazoli, F.1    Holmstrom, A.2    Forsberg, A.3    Magnusson, K.E.4
  • 27
    • 77149169405 scopus 로고    scopus 로고
    • Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches
    • Barreau F, et al. Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches. Gut. 2010;59(2):207-217.
    • (2010) Gut , vol.59 , Issue.2 , pp. 207-217
    • Barreau, F.1
  • 28
    • 25444476788 scopus 로고    scopus 로고
    • Yersinia outer proteins: Role in modulation of host cell signaling responses and pathogenesis
    • DOI 10.1146/annurev.micro.59.030804.121320
    • Viboud GI, Bliska JB. Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis. Annu Rev Microbiol. 2005;59:69-89. (Pubitemid 41507424)
    • (2005) Annual Review of Microbiology , vol.59 , pp. 69-89
    • Viboud, G.I.1    Bliska, J.B.2
  • 29
    • 13844308129 scopus 로고    scopus 로고
    • Mechanism of TNF-alpha modulation of Caco-2 intestinal epithelial tight junction barrier: Role of myosin light-chain kinase protein expression
    • DOI 10.1152/ajpgi.00412.2004
    • Ma TY, Boivin MA, Ye D, Pedram A, Said HM. Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression. Am J Physiol Gastrointest Liver Physiol. 2005;288(3):G422-G430. (Pubitemid 40261739)
    • (2005) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.288 , Issue.3
    • Ma, T.Y.1    Boivin, M.A.2    Ye, D.3    Pedram, A.4    Said, H.M.5
  • 30
    • 71949092030 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium
    • Cattin AL, et al. Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium. Mol Cell Biol. 2009;29(23):6294-6308.
    • (2009) Mol Cell Biol , vol.29 , Issue.23 , pp. 6294-6308
    • Cattin, A.L.1
  • 31
    • 77955593094 scopus 로고    scopus 로고
    • ClC-2 regulates mucosal barrier function associated with structural changes to the villus and epithelial tight junction
    • Nighot PK, Blikslager AT. ClC-2 regulates mucosal barrier function associated with structural changes to the villus and epithelial tight junction. Am J Physiol Gastrointest Liver Physiol. 2010; 299(2):G449-G456.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299 , Issue.2
    • Nighot, P.K.1    Blikslager, A.T.2
  • 32
    • 54949156390 scopus 로고    scopus 로고
    • Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis
    • Ragnarsson EG, et al. Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis. Lab Invest. 2008; 88(11):1215-1226.
    • (2008) Lab Invest , vol.88 , Issue.11 , pp. 1215-1226
    • Ragnarsson, E.G.1
  • 33
    • 21544450007 scopus 로고    scopus 로고
    • Listeriolysin O-induced membrane permeation mediates persistent interleukin-6 production in Caco-2 cells during Listeria monocytogenes infection in vitro
    • DOI 10.1128/IAI.73.7.3869-3877.2005
    • Tsuchiya K, Kawamura I, Takahashi A, Nomura T, Kohda C, Mitsuyama M. Listeriolysin O-induced membrane permeation mediates persistent interleukin-6 production in Caco-2 cells during Listeria monocytogenes infection in vitro. Infect Immun. 2005; 73(7):3869-3877. (Pubitemid 40923124)
    • (2005) Infection and Immunity , vol.73 , Issue.7 , pp. 3869-3877
    • Tsuchiya, K.1    Kawamura, I.2    Takahashi, A.3    Nomura, T.4    Kohda, C.5    Mitsuyama, M.6
  • 34
    • 0034799581 scopus 로고    scopus 로고
    • EPEC-activated ERK1/2 participate in inflammatory response but not tight junction barrier disruption
    • Savkovic SD, Ramaswamy A, Koutsouris A, Hecht G. EPEC-activated ERK1/2 participate in inflammatory response but not tight junction barrier disruption. Am J Physiol Gastrointest Liver Physiol. 2001; 281(4):G890-G898.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281 , Issue.4
    • Savkovic, S.D.1    Ramaswamy, A.2    Koutsouris, A.3    Hecht, G.4
  • 35
    • 0028961732 scopus 로고
    • Enteropathogenic Escherichia coli adherence to intestinal epithelial monolayers diminishes barrier function
    • Spitz J, Yuhan R, Koutsouris A, Blatt C, Alverdy J, Hecht G. Enteropathogenic Escherichia coli adherence to intestinal epithelial monolayers diminishes barrier function. Am J Physiol. 1995; 268(2 pt 1):G374-G379.
    • (1995) Am J Physiol , vol.268 , Issue.2 PART 1
    • Spitz, J.1    Yuhan, R.2    Koutsouris, A.3    Blatt, C.4    Alverdy, J.5    Hecht, G.6
  • 36
    • 0024204607 scopus 로고
    • Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers
    • Hecht G, Pothoulakis C, LaMont JT, Madara JL. Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers. J Clin Invest. 1988;82(5):1516-1524. (Pubitemid 19007753)
    • (1988) Journal of Clinical Investigation , vol.82 , Issue.5 , pp. 1516-1524
    • Hecht, G.1    Pothoulakis, C.2    LaMont, J.T.3    Madara, J.L.4
  • 37
    • 84855644351 scopus 로고    scopus 로고
    • Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and crohn's disease patients
    • Denizot J, et al. Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and crohn's disease patients. Inflamm Bowel Dis. 2012;18(2):294-304.
    • (2012) Inflamm Bowel Dis , vol.18 , Issue.2 , pp. 294-304
    • Denizot, J.1
  • 38
    • 0037040188 scopus 로고    scopus 로고
    • Protein kinase C signaling regulates ZO-1 translocation and increased paracellular flux of T84 colonocytes exposed to Clostridium difficile toxin A
    • DOI 10.1074/jbc.M109254200
    • Chen ML, Pothoulakis C, LaMont JT. Protein kinase C signaling regulates ZO-1 translocation and increased paracellular flux of T84 colonocytes exposed to Clostridium difficile toxin A. J Biol Chem. 2002;277(6):4247-4254. (Pubitemid 34968688)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.6 , pp. 4247-4254
    • Chen, M.L.1    Pothoulakis, C.2    Thomas, L.J.3
  • 39
    • 0030775148 scopus 로고    scopus 로고
    • Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability
    • Yuhan R, Koutsouris A, Savkovic SD, Hecht G. Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability. Gastroenterology. 1997; 113(6):1873-1882. (Pubitemid 27512145)
    • (1997) Gastroenterology , vol.113 , Issue.6 , pp. 1873-1882
    • Yuhan, R.1    Koutsouris, A.2    Savkovlc, S.D.3    Hecht, G.4
  • 41
    • 15544369643 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease
    • DOI 10.1016/S1473-3099(05)01308-3
    • Schroder NW, Schumann RR. Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease. Lancet Infect Dis. 2005; 5(3):156-164. (Pubitemid 40568671)
    • (2005) Lancet Infectious Diseases , vol.5 , Issue.3 , pp. 156-164
    • Schroder, N.W.J.1    Schumann, R.R.2
  • 42
    • 77149169405 scopus 로고    scopus 로고
    • Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches
    • Barreau F, et al. Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches. Gut. 2010;59(2):207-217.
    • (2010) Gut , vol.59 , Issue.2 , pp. 207-217
    • Barreau, F.1
  • 43
    • 3242692641 scopus 로고    scopus 로고
    • Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C
    • DOI 10.1053/j.gastro.2004.04.015, PII S0016508504007103
    • Cario E, Gerken G, Podolsky DK. Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. Gastroenterology. 2004;127(1):224-238. (Pubitemid 38962290)
    • (2004) Gastroenterology , vol.127 , Issue.1 , pp. 224-238
    • Cario, E.1    Gerken, G.2    Podolsky, D.K.3
  • 44
    • 34247235029 scopus 로고    scopus 로고
    • Toll-Like Receptor 2 Controls Mucosal Inflammation by Regulating Epithelial Barrier Function
    • DOI 10.1053/j.gastro.2007.02.056, PII S0016508507004155
    • Cario E, Gerken G, Podolsky DK. Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function. Gastroenterology. 2007; 132(4):1359-1374. (Pubitemid 46627595)
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. 1359-1374
    • Cario, E.1    Gerken, G.2    Podolsky, D.K.3
  • 45
    • 4444253690 scopus 로고    scopus 로고
    • NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
    • DOI 10.1038/ni1092
    • Watanabe T, Kitani A, Murray PJ, Strober W. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol. 2004;5(8):800-808. (Pubitemid 39172973)
    • (2004) Nature Immunology , vol.5 , Issue.8 , pp. 800-808
    • Watanabe, T.1    Kitani, A.2    Murray, P.J.3    Strober, W.4
  • 47
    • 37649013801 scopus 로고    scopus 로고
    • Chronic stimulation of Nod2 mediates tolerance to bacterial products
    • Hedl M, Li J, Cho JH, Abraham C. Chronic stimulation of Nod2 mediates tolerance to bacterial products. Proc Natl Acad Sci U S A. 2007; 104(49):19440-19445.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.49 , pp. 19440-19445
    • Hedl, M.1    Li, J.2    Cho, J.H.3    Abraham, C.4
  • 48
    • 0034667840 scopus 로고    scopus 로고
    • Mechanism of extracellular calcium regulation of intestinal epithelial tight junction permeability: Role of cytoskeletal involvement
    • Ma TY, Tran D, Hoa N, Nguyen D, Merryfield M, Tarnawski A. Mechanism of extracellular calcium regulation of intestinal epithelial tight junction permeability: role of cytoskeletal involvement. Microsc Res Tech. 2000;51(2):156-168.
    • (2000) Microsc Res Tech , vol.51 , Issue.2 , pp. 156-168
    • Ma, T.Y.1    Tran, D.2    Hoa, N.3    Nguyen, D.4    Merryfield, M.5    Tarnawski, A.6
  • 49
    • 0030669302 scopus 로고    scopus 로고
    • Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation
    • Turner JR, et al. Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation. Am J Physiol. 1997; 273(4 pt 1):C1378-C1385.
    • (1997) Am J Physiol , vol.273 , Issue.4 PART 1
    • Turner, J.R.1
  • 50
    • 0032036518 scopus 로고    scopus 로고
    • Signal Transduction Pathways Involved in Enterohemorrhagic Escherichia coli-Induced Alterations in T84 Epithelial Permeability
    • Philpott DJ, McKay DM, Mak W, Perdue MH, Sherman PM. Signal transduction pathways involved in enterohemorrhagic Escherichia coli-induced alterations in T84 epithelial permeability. Infect Immun. 1998;66(4):1680-1687. (Pubitemid 128471535)
    • (1998) Infection and Immunity , vol.66 , Issue.4 , pp. 1680-1687
    • Philpott, D.J.1    Mckay, D.M.2    Mak, W.3    Perdue, M.H.4    Sherman, P.M.5
  • 51
    • 0036789132 scopus 로고    scopus 로고
    • Intestinal infection with Giardia spp. reduces epithelial barrier function in a myosin light chain kinase-dependent fashion
    • Scott KG, Meddings JB, Kirk DR, Lees-Miller SP, Buret AG. Intestinal infection with Giardia spp. reduces epithelial barrier function in a myosin light chain kinase-dependent fashion. Gastroenterology. 2002;123(4):1179-1190.
    • (2002) Gastroenterology , vol.123 , Issue.4 , pp. 1179-1190
    • Scott, K.G.1    Meddings, J.B.2    Kirk, D.R.3    Lees-Miller, S.P.4    Buret, A.G.5
  • 53
    • 0036192679 scopus 로고    scopus 로고
    • Origin, originality, functions, subversions and molecular signalling of macropinocytosis
    • Amyere M, et al. Origin, originality, functions, subversions and molecular signalling of macropinocytosis. Int J Med Microbiol. 2002;291(6-7):487-494.
    • (2002) Int J Med Microbiol , vol.291 , Issue.6-7 , pp. 487-494
    • Amyere, M.1
  • 55
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • DOI 10.1016/S1074-7613(00)80086-2
    • Kawai T, Adachi O, Ogawa T, Takeda K, Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity. 1999;11(1):115-122. (Pubitemid 29359962)
    • (1999) Immunity , vol.11 , Issue.1 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 56
    • 0029908022 scopus 로고    scopus 로고
    • The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity
    • Hakansson S, et al. The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity. Embo J. 1996;15(21):5812-5823. (Pubitemid 26375503)
    • (1996) EMBO Journal , vol.15 , Issue.21 , pp. 5812-5823
    • Hakansson, S.1    Schesser, K.2    Persson, C.3    Galyov, E.E.4    Rosqvist, R.5    Homble, F.6    Wolf-Watz, H.7
  • 57
    • 0036139428 scopus 로고    scopus 로고
    • Plasmidic versus insertional cloning of heterologous genes in Mycobacterium bovis BCG: Impact on in vivo antigen persistence and immune responses
    • DOI 10.1128/IAI.70.1.303-314.2002
    • Mederle I, et al. Plasmidic versus insertional cloning of heterologous genes in Mycobacterium bovis BCG: impact on in vivo antigen persistence and immune responses. Infect Immun. 2002;70(1):303-314. (Pubitemid 34028631)
    • (2002) Infection and Immunity , vol.70 , Issue.1 , pp. 303-314
    • Mederle, I.1    Bourguin, I.2    Ensergueix, D.3    Badell, E.4    Moniz-Peireira, J.5    Gicquel, B.6    Winter, N.7
  • 58
    • 1342325735 scopus 로고    scopus 로고
    • Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection
    • DOI 10.1046/j.1462-5822.2004.00368.x
    • Rousseau C, et al. Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection. Cell Microbiol. 2004;6(3):277-287. (Pubitemid 38248011)
    • (2004) Cellular Microbiology , vol.6 , Issue.3 , pp. 277-287
    • Rousseau, C.1    Winter, N.2    Privert, E.3    Bordat, Y.4    Neyrolles, O.5    Ave, P.6    Huerre, M.7    Gicquel, B.8    Jackson, M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.