Quantitative metabolomic profiling of serum, plasma, and urine by 1H NMR spectroscopy discriminates between patients with inflammatory bowel disease and healthy individuals

Journal of Proteome Research

Volumn 11, Issue 6, 2012, Pages 3344-3357

  Schicho, Rudolf ^a,b   Shaykhutdinov, Rustem ^c   Ngo, Jennifer ^a   Nazyrova, Alsu ^c   Schneider, Christopher ^a   Panaccione, Remo ^a   Kaplan, Gilaad G ^a   Vogel, Hans J ^c   Storr, Martin ^a,d  

^a Snyder Institute of Infection Immunity and Inflammation   (Canada)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF MUNICH   (Germany)

Author keywords

chemometrics; inflammatory bowel disease; metabonomics; OPLS

Indexed keywords

2 HYDROXYBUTYRATE DEHYDROGENASE; 3 METHYL 2 OXOVALERIC ACID; ALLANTOIN; AMIDE; ARGININE; BETAINE; CARNITINE; CHOLINESTERASE; CITRIC ACID; CREATINE; CREATININE; FORMIC ACID; GALACTOSE; GLUCOSE; HIPPURIC ACID; ISOLEUCINE; LACTIC ACID; LYSINE; MALTOSE; MANNITOL; MANNOSE; METHANOL; OXOACID; PYRUVIC ACID; SERINE; SUCCINIC ACID; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; UREA; XYLOSE;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CROHN DISEASE; DISEASE MARKER; FEMALE; HUMAN; HUMAN TISSUE; MALE; METABOLOMICS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; SEROLOGY; ULCERATIVE COLITIS; URINALYSIS; AREA UNDER THE CURVE; BLOOD; CASE CONTROL STUDY; COLITIS, ULCERATIVE; DIFFERENTIAL DIAGNOSIS; METABOLOME; MIDDLE AGED; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRINCIPAL COMPONENT ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; URINE; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; CASE-CONTROL STUDIES; COLITIS, ULCERATIVE; CROHN DISEASE; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOME; MIDDLE AGED; MULTIVARIATE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; ROC CURVE; YOUNG ADULT;

EID: 84861808541     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr300139q     Document Type: Article

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