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Volumn 18, Issue 3, 2012, Pages 225-234

Regenerative tendon and ligament healing: Opportunities with recombinant human platelet-derived growth factor BB-Homodimer

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICAL PROPERTIES; EXTRACELLULAR MATRIX DEPOSITION; LIGAMENT HEALING; LIGAMENT INJURY; MITOGENIC; PLATELET-DERIVED GROWTH FACTORS; PRECLINICAL STUDIES; SCAR TISSUES; TENDON HEALING;

EID: 84861804831     PISSN: 19373368     EISSN: 19373376     Source Type: Journal    
DOI: 10.1089/ten.teb.2011.0603     Document Type: Review
Times cited : (33)

References (109)
  • 1
    • 11844274558 scopus 로고    scopus 로고
    • Tendon injury and tendinopathy: Healing and repair
    • Sharma, P., and Maffulli, N. Tendon injury and tendinopathy: healing and repair. J Bone Joint SurgAm87, 187, 2005.
    • (2005) J Bone Joint SurgAm87 , pp. 187
    • Sharma, P.1    Maffulli, N.2
  • 2
    • 0348226283 scopus 로고    scopus 로고
    • Regenerative versus reparative healing in tendon: A study of biochemical and histological properties in fetal sheep
    • Beredjiklian, P., Favata, M., Cartmell, J.S., Flanagan, C.L., Crombleholme, T.M., and Soslowsky, L.J. Regenerative versus reparative healing in tendon: a study of biochemical and histological properties in fetal sheep. Ann Biomed Eng 31, 1143, 2003.
    • (2003) Ann Biomed Eng , vol.31 , pp. 1143
    • Beredjiklian, P.1    Favata, M.2    Cartmell, J.S.3    Flanagan, C.L.4    Crombleholme, T.M.5    Soslowsky, L.J.6
  • 3
    • 38849090654 scopus 로고    scopus 로고
    • Tendon: Biology, biomechanics, repair, growth factors and evolving treatment options
    • James, R., Kesturu, G., Balian, G., and Chhabra, A. Tendon: biology, biomechanics, repair, growth factors and evolving treatment options. J Hand Surg Am 33, 102, 2008.
    • (2008) J Hand Surg Am , vol.33 , pp. 102
    • James, R.1    Kesturu, G.2    Balian, G.3    Chhabra, A.4
  • 4
    • 79958826761 scopus 로고    scopus 로고
    • Tissue engineered biological augmentation for tendon healing: A systematic review
    • Longo, U.G., Lamberti, A., Maffulli, N., and Denaro, V. Tissue engineered biological augmentation for tendon healing: a systematic review. Br Med Bull 98, 31, 2011.
    • (2011) Br Med Bull , vol.98 , pp. 31
    • Longo, U.G.1    Lamberti, A.2    Maffulli, N.3    Denaro, V.4
  • 5
    • 77952529143 scopus 로고    scopus 로고
    • Strategies in biologic augmentation of rotator cuff repair: A review
    • Cheung, E.V., Silverio, L., and Sperling, J.W. Strategies in biologic augmentation of rotator cuff repair: a review. Clin Orthop Rel Res 468, 1476, 2010.
    • (2010) Clin Orthop Rel Res , vol.468 , pp. 1476
    • Cheung, E.V.1    Silverio, L.2    Sperling, J.W.3
  • 6
    • 84855829524 scopus 로고    scopus 로고
    • Tendon phenotype should dictate tissue engineering modality in tendon repair: A review
    • Gott, M., Ast, M., Lane, L.B., Schwartz, J.A., Catanzano, A., Razzano, P., et al. Tendon phenotype should dictate tissue engineering modality in tendon repair: a review. Discov Med 12, 75, 2011.
    • (2011) Discov Med , vol.12 , pp. 75
    • Gott, M.1    Ast, M.2    Lane, L.B.3    Schwartz, J.A.4    Catanzano, A.5    Razzano, P.6
  • 7
    • 1642475081 scopus 로고    scopus 로고
    • Autologous platelets as a source of proteins for healing and tissue regeneration
    • Anitua, E., Andia, I., Ardanza, B., Nurden, P., and Nurden, A.T. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 91, 4, 2004.
    • (2004) Thromb Haemost , vol.91 , pp. 4
    • Anitua, E.1    Andia, I.2    Ardanza, B.3    Nurden, P.4    Nurden, A.T.5
  • 8
    • 79952307230 scopus 로고    scopus 로고
    • Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems
    • Castillo, T., Pouliot, M., Kim, H., and Dragoo, J. Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems. Am J Sports Med 39, 266, 2011.
    • (2011) Am J Sports Med , vol.39 , pp. 266
    • Castillo, T.1    Pouliot, M.2    Kim, H.3    Dragoo, J.4
  • 9
    • 1642301324 scopus 로고    scopus 로고
    • Comparison of methods for point of care preparation of autologous platelet gel
    • Kevy, S., and Jacobson, M. Comparison of methods for point of care preparation of autologous platelet gel. J Extra Corpor Technol 32, 28, 2004.
    • (2004) J Extra Corpor Technol , vol.32 , pp. 28
    • Kevy, S.1    Jacobson, M.2
  • 10
    • 14944364940 scopus 로고    scopus 로고
    • Platelet quantification and growth factor analysis from platelet rich plasma: Implications for wound healing
    • Eppley, B., Woodell, J., and Higgins, J. Platelet quantification and growth factor analysis from platelet rich plasma: implications for wound healing. Plast Reconstr Surg 114, 1502, 2004.
    • (2004) Plast Reconstr Surg , vol.114 , pp. 1502
    • Eppley, B.1    Woodell, J.2    Higgins, J.3
  • 11
    • 33750540817 scopus 로고    scopus 로고
    • Platelet-rich plasma preparation using three devices: Implications for platelet activation and platelet growth factor release
    • Everts, P., Mahoney, C., Hoffmann, J., Schonberger, J., Box, H., van Zundert, A., et al. Platelet-rich plasma preparation using three devices: implications for platelet activation and platelet growth factor release. Growth Factors 24, 165, 2006.
    • (2006) Growth Factors , vol.24 , pp. 165
    • Everts, P.1    Mahoney, C.2    Hoffmann, J.3    Schonberger, J.4    Box, H.5    Van Zundert, A.6
  • 12
    • 0043261429 scopus 로고    scopus 로고
    • An in vitro and in vivo evaluation of autologous platelet concentrate in oral reconstruction
    • Babbush, C.A., Kevy, S.V., and Jacobson, M.S. An in vitro and in vivo evaluation of autologous platelet concentrate in oral reconstruction. Implant Dent 12, 24, 2003.
    • (2003) Implant Dent , vol.12 , pp. 24
    • Babbush, C.A.1    Kevy, S.V.2    Jacobson, M.S.3
  • 13
    • 77951969379 scopus 로고    scopus 로고
    • Autologous growth factor injections in chronic tendinopathy: A systematic review
    • de Vos, R.J., van Veldhoven PLJ, Moen, M.H., Weir, A., Tol, J.L., and Mafulli, N. Autologous growth factor injections in chronic tendinopathy: a systematic review. Br Med Bull 95, 63, 2010.
    • (2010) Br Med Bull , vol.95 , pp. 63
    • De Vos, R.J.1    Van Veldhoven Plj2    Moen, M.H.3    Weir, A.4    Tol, J.L.5    Mafulli, N.6
  • 14
    • 78650300731 scopus 로고    scopus 로고
    • Autologous platelet-rich plasma: A revolution in soft tissue sports injury management?
    • Mei-Dan, O., Lippi, G., Sanchez, M., Andia, I., and Mafulli, N. Autologous platelet-rich plasma: a revolution in soft tissue sports injury management? Phys Sportsmed 38, 127, 2010.
    • (2010) Phys Sportsmed , vol.38 , pp. 127
    • Mei-Dan, O.1    Lippi, G.2    Sanchez, M.3    Andia, I.4    Mafulli, N.5
  • 16
    • 33846405718 scopus 로고    scopus 로고
    • Comparison of surgically repaired achilles tendon tears using platelet-rich fibrin matrices
    • Sanchez, M., Anitua, E., Azofra, J., Andia, I., Padilla, S., and Mujika, I. Comparison of surgically repaired achilles tendon tears using platelet-rich fibrin matrices. Am J Sports Med 35, 245, 2007.
    • (2007) Am J Sports Med , vol.35 , pp. 245
    • Sanchez, M.1    Anitua, E.2    Azofra, J.3    Andia, I.4    Padilla, S.5    Mujika, I.6
  • 17
    • 78651404912 scopus 로고    scopus 로고
    • Autologous platelets have no effect on the healing of human achilles tendon ruptures. A randomized single-blind study
    • Schepull, T., Kvist, J., Norrman, H., Trinks, M., Berlin, G., and Aspenberg, P. Autologous platelets have no effect on the healing of human achilles tendon ruptures. A randomized single-blind study. Am J Sports Med 39, 38, 2011.
    • (2011) Am J Sports Med , vol.39 , pp. 38
    • Schepull, T.1    Kvist, J.2    Norrman, H.3    Trinks, M.4    Berlin, G.5    Aspenberg, P.6
  • 18
    • 79955831900 scopus 로고    scopus 로고
    • Platelet rich plasma in arthroscopic rotator cuff repair: A prospective RCT study, 2-year follow-up
    • Randelli, P., Arrigoni, P., Ragone, V., Aliprandi, A., and Cabitza, P. Platelet rich plasma in arthroscopic rotator cuff repair: a prospective RCT study, 2-year follow-up. J Shoulder Elbow Surg 20, 518, 2011.
    • (2011) J Shoulder Elbow Surg , vol.20 , pp. 518
    • Randelli, P.1    Arrigoni, P.2    Ragone, V.3    Aliprandi, A.4    Cabitza, P.5
  • 19
    • 79960947167 scopus 로고    scopus 로고
    • Rotator cuff repair healing influenced by platelet-rich plasma construct augmentation
    • Barber, F.A., Hrnack, S.A., Snyder, S.J., and Hapa, O. Rotator cuff repair healing influenced by platelet-rich plasma construct augmentation. Arthroscopy 27, 1029, 2011.
    • (2011) Arthroscopy , vol.27 , pp. 1029
    • Barber, F.A.1    Hrnack, S.A.2    Snyder, S.J.3    Hapa, O.4
  • 20
    • 79952309929 scopus 로고    scopus 로고
    • Platelet-rich plasma augmentation for arthroscopic rotator cuff repair: A randomized controlled trial
    • Castricini, R., Longo, U.G., De Benedetto, M., Panfoli, N., Pirani, P., Zini, R., et al. Platelet-rich plasma augmentation for arthroscopic rotator cuff repair: a randomized controlled trial. Am J Sports Med 39, 258, 2011.
    • (2011) Am J Sports Med , vol.39 , pp. 258
    • Castricini, R.1    Longo, U.G.2    De Benedetto, M.3    Panfoli, N.4    Pirani, P.5    Zini, R.6
  • 21
    • 67349131552 scopus 로고    scopus 로고
    • Platelet-rich plasma: New clinical application: A pilot study for treatment of jumper's knee
    • Kon, E., Filardo, G., Delcogliano, M., Presti, M.L., Russo, A., Bondi, A., et al. Platelet-rich plasma: new clinical application: a pilot study for treatment of jumper's knee. Injury 40, 598, 2009.
    • (2009) Injury , vol.40 , pp. 598
    • Kon, E.1    Filardo, G.2    Delcogliano, M.3    Presti, M.L.4    Russo, A.5    Bondi, A.6
  • 23
    • 79952535413 scopus 로고    scopus 로고
    • No effects of PRP on ultrasonographic tendon structure and neovascularisation in chronic midportion Achilles tendinopathy
    • de Vos, R.J., Weir, A., Tol, J.L., Verhaar, J.A., Weinans, H., and van Schie, H.T. No effects of PRP on ultrasonographic tendon structure and neovascularisation in chronic midportion Achilles tendinopathy. Br J Sports Med 45, 387, 2011.
    • (2011) Br J Sports Med , vol.45 , pp. 387
    • De Vos, R.J.1    Weir, A.2    Tol, J.L.3    Verhaar, J.A.4    Weinans, H.5    Van Schie, H.T.6
  • 24
    • 33750957498 scopus 로고    scopus 로고
    • Treatment of chronic elbow tendinosis with buffered platelet-rich plasma
    • Mishra, A., and Pavelko, T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med 34, 1774, 2006.
    • (2006) Am J Sports Med , vol.34 , pp. 1774
    • Mishra, A.1    Pavelko, T.2
  • 25
    • 76849103704 scopus 로고    scopus 로고
    • Positive effect of an autologous platelet concentration in lateral epicondylitis in a double-blind randomized controlled trial: Platelet-rich plasma versus corticosteroid injection with a 1-year follow-up
    • Peerbooms, J.C., Sluimer, J., Bruijn, D.J., and Gosens, T. Positive effect of an autologous platelet concentration in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-year follow-up. Am J Sports Med 38, 255, 2010.
    • (2010) Am J Sports Med , vol.38 , pp. 255
    • Peerbooms, J.C.1    Sluimer, J.2    Bruijn, D.J.3    Gosens, T.4
  • 26
    • 79957612332 scopus 로고    scopus 로고
    • Ongoing positive effect of platelet-rich plasma versus corticosteroid injection in lateral epicondylitis. A doubleblind randomized controlled trial with 2-year follow-up
    • Gosens, T., Peerbooms, J., van Laar, W., and den Oudsten, B. Ongoing positive effect of platelet-rich plasma versus corticosteroid injection in lateral epicondylitis. A doubleblind randomized controlled trial with 2-year follow-up. Am J Sports Med 39, 1200, 2011.
    • (2011) Am J Sports Med , vol.39 , pp. 1200
    • Gosens, T.1    Peerbooms, J.2    Van Laar, W.3    Den Oudsten, B.4
  • 27
    • 0029023981 scopus 로고
    • Growth factors and canine flexor tendon healing: Initial studies in uninjured and repair models
    • Duffy, F.J., Seiler, J.G., Gelberman, R.H., and Hergrueter, C.A. Growth factors and canine flexor tendon healing: initial studies in uninjured and repair models. J Hand Surg Am 20, 645, 1995.
    • (1995) J Hand Surg Am , vol.20 , pp. 645
    • Duffy, F.J.1    Seiler, J.G.2    Gelberman, R.H.3    Hergrueter, C.A.4
  • 28
    • 0032248213 scopus 로고    scopus 로고
    • Growth factor expression in healing rabbit medial collateral and anterior cruciate ligaments
    • Lee, J., Harwood, F.L., Akeson, W.H., and Amiel, D. Growth factor expression in healing rabbit medial collateral and anterior cruciate ligaments. Iowa Orthop J 18, 19, 1998.
    • (1998) Iowa Orthop J , vol.18 , pp. 19
    • Lee, J.1    Harwood, F.L.2    Akeson, W.H.3    Amiel, D.4
  • 29
    • 4644296349 scopus 로고    scopus 로고
    • Expression of growth factors in canine flexor tendon after laceration in vivo
    • Tsubone, T., Moran, S., Amadio, P.C., Zhao, C., and An, K. Expression of growth factors in canine flexor tendon after laceration in vivo. Ann Plast Surg 53, 393, 2004.
    • (2004) Ann Plast Surg , vol.53 , pp. 393
    • Tsubone, T.1    Moran, S.2    Amadio, P.C.3    Zhao, C.4    An, K.5
  • 30
    • 33747603714 scopus 로고    scopus 로고
    • Nucleotide structure of equine platelet-derived growth factor-A and-B and expression in horses with induced acute tendinitis
    • Donnelly, B.P., Nixon, A.J., Haupt, J.L., and Dahlgren, L. Nucleotide structure of equine platelet-derived growth factor-A and-B and expression in horses with induced acute tendinitis. Am J Vet Res 67, 1218, 2005.
    • (2005) Am J Vet Res , vol.67 , pp. 1218
    • Donnelly, B.P.1    Nixon, A.J.2    Haupt, J.L.3    Dahlgren, L.4
  • 33
    • 0033658226 scopus 로고    scopus 로고
    • Localization of growth factors in the reconstructed anterior cruciate ligament: Immunohistological study in dogs
    • Kuroda, R., Kurosaka, M., Yoshiya, S., and Mizuno, K. Localization of growth factors in the reconstructed anterior cruciate ligament: immunohistological study in dogs. Knee Surg Sports Traumatol Arthrosc 8, 120, 2000.
    • (2000) Knee Surg Sports Traumatol Arthrosc , vol.8 , pp. 120
    • Kuroda, R.1    Kurosaka, M.2    Yoshiya, S.3    Mizuno, K.4
  • 34
    • 0031688508 scopus 로고    scopus 로고
    • A review of nonclinical toxicology studies of becaplermin (rhPDGF-BB)
    • Knight, E.V., Oldham, J.W., Mohler, M., Liu, S., and Dooley, J. A review of nonclinical toxicology studies of becaplermin (rhPDGF-BB). Am J Surg 176, 55S, 1998.
    • (1998) Am J Surg , vol.176
    • Knight, E.V.1    Oldham, J.W.2    Mohler, M.3    Liu, S.4    Dooley, J.5
  • 35
    • 0031713762 scopus 로고    scopus 로고
    • Clinical safety of becaplermin (rhPDGF-BB) gel
    • Smiell, J.M. Clinical safety of becaplermin (rhPDGF-BB) gel. Am J Surg 176, 68S, 1998.
    • (1998) Am J Surg , vol.176
    • Smiell, J.M.1
  • 36
    • 3142690429 scopus 로고    scopus 로고
    • Clinical implications of growth factors in flexor tendon wound healing
    • Hsu, C., and Chang, J. Clinical implications of growth factors in flexor tendon wound healing. J Hand Surg 29-A, 551, 2004.
    • (2004) J Hand Surg , vol.29 A , pp. 551
    • Hsu, C.1    Chang, J.2
  • 37
    • 0037877976 scopus 로고    scopus 로고
    • The roles of growth factors in tendon and ligament healing
    • Molloy, T., Wang, Y., and Murrell, G.A.C. The roles of growth factors in tendon and ligament healing. Sports Med 33, 381, 2003.
    • (2003) Sports Med , vol.33 , pp. 381
    • Molloy, T.1    Wang, Y.2    Murrell, G.A.C.3
  • 38
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin, C.-H., and Westermark, B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 79, 1283, 1999.
    • (1999) Physiol Rev , vol.79 , pp. 1283
    • Heldin, C.-H.1    Westermark, B.2
  • 39
    • 33748175142 scopus 로고    scopus 로고
    • Biology of platelet-derived growth factor and its involvement in disease
    • Alvarez, R.H., Kantarjian, H.M., and Cortes, J.E. Biology of platelet-derived growth factor and its involvement in disease. Mayo Clin Proc 81, 1241, 2006.
    • (2006) Mayo Clin Proc , vol.81 , pp. 1241
    • Alvarez, R.H.1    Kantarjian, H.M.2    Cortes, J.E.3
  • 40
    • 0142243109 scopus 로고    scopus 로고
    • Roles of PDGF in animal development
    • Hoch, R.V., and Soriano, P. Roles of PDGF in animal development. Development 130, 4769, 2003.
    • (2003) Development , vol.130 , pp. 4769
    • Hoch, R.V.1    Soriano, P.2
  • 41
    • 0025067429 scopus 로고
    • Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets
    • Hart, C., Bailey, M., Curtis, D., Osborn, S., Raines, E., Ross, R., et al. Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets. Biochemistry 29, 166, 1990.
    • (1990) Biochemistry , vol.29 , pp. 166
    • Hart, C.1    Bailey, M.2    Curtis, D.3    Osborn, S.4    Raines, E.5    Ross, R.6
  • 42
    • 0025295662 scopus 로고
    • Platelet-derived growth factor receptor: Current views of the two-subunit model
    • Hart, C., and Bowen-Pope, D. Platelet-derived growth factor receptor: current views of the two-subunit model. J Invest Dermatol 94, 53S, 1990.
    • (1990) J Invest Dermatol , vol.94
    • Hart, C.1    Bowen-Pope, D.2
  • 43
    • 11144357325 scopus 로고    scopus 로고
    • PDGF C is a selective alpha plateletderived growth factor receptor agonist that is highly expressed in platelet alpha granules and vascular smooth muscle
    • Fang, L., Yan, Y., Komuves, L., Yonkovich, S., Sullivan, C., Stringer, B., et al. PDGF C is a selective alpha plateletderived growth factor receptor agonist that is highly expressed in platelet alpha granules and vascular smooth muscle. Arterioscler Thromb Vasc Biol 24, 787, 2004.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 787
    • Fang, L.1    Yan, Y.2    Komuves, L.3    Yonkovich, S.4    Sullivan, C.5    Stringer, B.6
  • 44
    • 0023738922 scopus 로고
    • A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain
    • Hammacher, A., Hellman, U., Johnsson, A., Ostman, A., Gunnarsson, K., Westermark, B., et al. A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain. J Biol Chem 263, 16493, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 16493
    • Hammacher, A.1    Hellman, U.2    Johnsson, A.3    Ostman, A.4    Gunnarsson, K.5    Westermark, B.6
  • 45
    • 0020046560 scopus 로고
    • Chemotaxis of monocytes and neutrophils to platelet-derived growth factor
    • Deuel, T., Senior, R., Huang, J., and Griffin, G. Chemotaxis of monocytes and neutrophils to platelet-derived growth factor. J Clin Invest 69, 1046, 1982.
    • (1982) J Clin Invest , vol.69 , pp. 1046
    • Deuel, T.1    Senior, R.2    Huang, J.3    Griffin, G.4
  • 46
    • 0021751289 scopus 로고
    • Platelet-derived growth factor promotes polymorphonuclear leukocyte activation
    • Tzeng, D., Deuel, T., Huang, J., Senior, R., Boxer, L., and Baehner, R. Platelet-derived growth factor promotes polymorphonuclear leukocyte activation. Blood 64, 1123, 1984.
    • (1984) Blood , vol.64 , pp. 1123
    • Tzeng, D.1    Deuel, T.2    Huang, J.3    Senior, R.4    Boxer, L.5    Baehner, R.6
  • 47
    • 0021830028 scopus 로고
    • Plateletderived growth factor promotes human peripheral monocyte activation
    • Tzeng, D., Deuel, T., Huang, J., and Baehner, R. Plateletderived growth factor promotes human peripheral monocyte activation. Blood 66, 179, 1985.
    • (1985) Blood , vol.66 , pp. 179
    • Tzeng, D.1    Deuel, T.2    Huang, J.3    Baehner, R.4
  • 48
    • 0025216650 scopus 로고
    • Differential effects of the various isoforms of plateletderived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes
    • Siegbahn, A., Hammacher, A., Westermark, B., and Heldin, C. Differential effects of the various isoforms of plateletderived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes. J Clin Invest 85, 916, 1990.
    • (1990) J Clin Invest , vol.85 , pp. 916
    • Siegbahn, A.1    Hammacher, A.2    Westermark, B.3    Heldin, C.4
  • 49
    • 0027367406 scopus 로고
    • Expression of platelet-derived growth factor beta receptor on human monocyte-derived macrophages and effects of platelet-derived growth factor BB dimer on the cellular function
    • Inaba, T., Shimano, H., Gotoda, T., Harada, K., Shimada, M., Ohsuga, J., et al. Expression of platelet-derived growth factor beta receptor on human monocyte-derived macrophages and effects of platelet-derived growth factor BB dimer on the cellular function. J Biol Chem 268, 24353, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 24353
    • Inaba, T.1    Shimano, H.2    Gotoda, T.3    Harada, K.4    Shimada, M.5    Ohsuga, J.6
  • 50
    • 0029551217 scopus 로고
    • Platelet-derived growth factor Distinct signal transduction pathways associated with migration versus proliferation
    • Bornfeldt, K.E., Raines, E.W., Graves, L.M., Skinner, M.P., Krebs, E.G., and Ross, R. Platelet-derived growth factor. Distinct signal transduction pathways associated with migration versus proliferation. Ann N Y Acad Sci 766, 416, 1995.
    • (1995) Ann N y Acad Sci , vol.766 , pp. 416
    • Bornfeldt, K.E.1    Raines, E.W.2    Graves, L.M.3    Skinner, M.P.4    Krebs, E.G.5    Ross, R.6
  • 51
    • 0033994703 scopus 로고    scopus 로고
    • Novel method for the quantitative assessment of cell migration: A study on the motility of anterior cruciate (ACL) and medial collateral ligament (MCL) cells
    • Kobayashi, K., Healey, R.M., Sah, R.L., Clark, J.J., Tu, B.P., Goomer, R.S., et al. Novel method for the quantitative assessment of cell migration: a study on the motility of anterior cruciate (ACL) and medial collateral ligament (MCL) cells. Tissue Eng 6, 29, 2000.
    • (2000) Tissue Eng , vol.6 , pp. 29
    • Kobayashi, K.1    Healey, R.M.2    Sah, R.L.3    Clark, J.J.4    Tu, B.P.5    Goomer, R.S.6
  • 52
    • 0035229079 scopus 로고    scopus 로고
    • The effect of cytokines on the migration of fibroblasts derived from different regions of the canine shoulder capsule
    • Suzuki, K., Attia, E., Hannafin, J., Rodeo, S., Warren, R., and Bhargava, M. The effect of cytokines on the migration of fibroblasts derived from different regions of the canine shoulder capsule. J Shoulder Elbow Surg 10, 62, 2001.
    • (2001) J Shoulder Elbow Surg , vol.10 , pp. 62
    • Suzuki, K.1    Attia, E.2    Hannafin, J.3    Rodeo, S.4    Warren, R.5    Bhargava, M.6
  • 53
    • 0029610147 scopus 로고
    • PDGF-BB, IGF-I and mechanical load stimulate DNA synthesis in avian tendon fibroblasts in vitro
    • Banes, A.J., Tsuzaki, M., Hu, P., Brigman, B., Brown, T., Almekinders, L., et al. PDGF-BB, IGF-I and mechanical load stimulate DNA synthesis in avian tendon fibroblasts in vitro. J Biomech 28, 1505, 1995.
    • (1995) J Biomech , vol.28 , pp. 1505
    • Banes, A.J.1    Tsuzaki, M.2    Hu, P.3    Brigman, B.4    Brown, T.5    Almekinders, L.6
  • 54
    • 33746684965 scopus 로고    scopus 로고
    • Tissue engineering of flexor tendons: Optimization of tenocyte proliferation using growth factor supplementation
    • Costa, M.A., Wu, C., Pham, B.V., Chong, A.K., Pham, H.M., and Chang, J. Tissue engineering of flexor tendons: optimization of tenocyte proliferation using growth factor supplementation. Tissue Eng 12, 1937, 2006.
    • (2006) Tissue Eng , vol.12 , pp. 1937
    • Costa, M.A.1    Wu, C.2    Pham, B.V.3    Chong, A.K.4    Pham, H.M.5    Chang, J.6
  • 55
    • 0037229235 scopus 로고    scopus 로고
    • The effect of selected growth factors on human anterior cruciate ligament cell interactions with a three-dimensional collagen-GAG scaffold
    • Meaney Murray, M., Rice, K., Wright, R., and Spector, M. The effect of selected growth factors on human anterior cruciate ligament cell interactions with a three-dimensional collagen-GAG scaffold. J Orthop Res 21, 238, 2003.
    • (2003) J Orthop Res , vol.21 , pp. 238
    • Meaney Murray, M.1    Rice, K.2    Wright, R.3    Spector, M.4
  • 56
    • 54949089299 scopus 로고    scopus 로고
    • Controlled-release kinetics and biologic activity of platelet-derived growth factor-BB for use in flexor tendon repair
    • Sakiyama-Elbert, S.E., Das, R., Gelberman, R.H., Harwood, F., Amiel, D., and Thomopoulos, S. Controlled-release kinetics and biologic activity of platelet-derived growth factor-BB for use in flexor tendon repair. J Hand Surg Am 33, 1548, 2008.
    • (2008) J Hand Surg Am , vol.33 , pp. 1548
    • Sakiyama-Elbert, S.E.1    Das, R.2    Gelberman, R.H.3    Harwood, F.4    Amiel, D.5    Thomopoulos, S.6
  • 57
    • 0029168411 scopus 로고
    • Proliferative responses to platelet-derived growth factor in young and old rat patellar tendon
    • Spindler, K.P., Nanney, L.B., and Davidson, J.M. Proliferative responses to platelet-derived growth factor in young and old rat patellar tendon. Connect Tissue Res 31, 171, 1995.
    • (1995) Connect Tissue Res , vol.31 , pp. 171
    • Spindler, K.P.1    Nanney, L.B.2    Davidson, J.M.3
  • 58
    • 0030198962 scopus 로고    scopus 로고
    • Patellar tendon and anterior cruciate ligament have different mitogenic responses to platelet-derived growth factor and transforming growth factor B
    • Spindler, K.P., Imro, A.K., Mayes, C.E., and Davidson, J.M. Patellar tendon and anterior cruciate ligament have different mitogenic responses to platelet-derived growth factor and transforming growth factor B. J Orthop Res 14, 542, 1996.
    • (1996) J Orthop Res , vol.14 , pp. 542
    • Spindler, K.P.1    Imro, A.K.2    Mayes, C.E.3    Davidson, J.M.4
  • 59
    • 19944422742 scopus 로고    scopus 로고
    • Effect of several growth factors on canine flexor tendon fibroblast proliferation and collagen synthesis in vitro
    • Thomopoulos, S., Harwood, F., Silva, M., Amiel, D., and Gelberman, R. Effect of several growth factors on canine flexor tendon fibroblast proliferation and collagen synthesis in vitro. J Hand Surg Am 30, 441, 2005.
    • (2005) J Hand Surg Am , vol.30 , pp. 441
    • Thomopoulos, S.1    Harwood, F.2    Silva, M.3    Amiel, D.4    Gelberman, R.5
  • 60
    • 34948878596 scopus 로고    scopus 로고
    • PDGF-BB released in tendon repair using a novel delivery system promotes cell proliferation and collagen remodeling
    • Thomopoulos, S., Zaegel, M., Das, R., Harwood, F., Silva, M., Amiel, D., et al. PDGF-BB released in tendon repair using a novel delivery system promotes cell proliferation and collagen remodeling. J Orthop Res 25, 1358, 2007.
    • (2007) J Orthop Res , vol.25 , pp. 1358
    • Thomopoulos, S.1    Zaegel, M.2    Das, R.3    Harwood, F.4    Silva, M.5    Amiel, D.6
  • 62
    • 0034964145 scopus 로고    scopus 로고
    • Dose-related cellular effects of platelet-derived growth factor-BB differ in various types of rabbit tendons in vitro
    • Yoshikawa, Y., and Abrahamsson, S.O. Dose-related cellular effects of platelet-derived growth factor-BB differ in various types of rabbit tendons in vitro. Acta Orthop Scand 72, 287, 2001.
    • (2001) Acta Orthop Scand , vol.72 , pp. 287
    • Yoshikawa, Y.1    Abrahamsson, S.O.2
  • 63
    • 77249143315 scopus 로고    scopus 로고
    • BFGF and PDGF-BB for tendon repair: Controlled release and biologic activity by tendon fibroblasts in vitro
    • Thomopoulos, S., Das, R., Sakiyama-Elbert, S., Silva, M., Charlton, N., and Gelberman, R. bFGF and PDGF-BB for tendon repair: controlled release and biologic activity by tendon fibroblasts in vitro. Ann Biomed Eng 38, 225, 2010.
    • (2010) Ann Biomed Eng , vol.38 , pp. 225
    • Thomopoulos, S.1    Das, R.2    Sakiyama-Elbert, S.3    Silva, M.4    Charlton, N.5    Gelberman, R.6
  • 64
    • 0033072033 scopus 로고    scopus 로고
    • Ideal concentration of growth factors in rabbit's flexor tendon culture
    • Kang, H.J., and Kang, E.S. Ideal concentration of growth factors in rabbit's flexor tendon culture. Yonsei Med J 40, 26, 1999.
    • (1999) Yonsei Med J , vol.40 , pp. 26
    • Kang, H.J.1    Kang, E.S.2
  • 67
    • 0028935418 scopus 로고
    • Effect of growth factors on the proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments
    • Schmidt, C.C., Georgescu, H.I., Kwoh, C.K., Blomstrom, G.L., Engle, C.P., Larkin, L.A., et al. Effect of growth factors on the proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments. J Orthop Res 13, 184, 1995.
    • (1995) J Orthop Res , vol.13 , pp. 184
    • Schmidt, C.C.1    Georgescu, H.I.2    Kwoh, C.K.3    Blomstrom, G.L.4    Engle, C.P.5    Larkin, L.A.6
  • 68
    • 0033033078 scopus 로고    scopus 로고
    • Characterization of chemotactic migration and growth kinetics of canine knee ligament fibroblasts
    • Hannafin, J.A., Attia, E.T., Warren, R.F., and Bhargava, M.M. Characterization of chemotactic migration and growth kinetics of canine knee ligament fibroblasts. J Orthop Res 17, 398, 1999.
    • (1999) J Orthop Res , vol.17 , pp. 398
    • Hannafin, J.A.1    Attia, E.T.2    Warren, R.F.3    Bhargava, M.M.4
  • 69
    • 0030110970 scopus 로고    scopus 로고
    • Proliferative and matrix synthesis response of canine anterior cruciate ligament fibroblasts submitted to combined growth factors
    • DesRosiers, E.A., Yahia, L., and Rivard, C.-H. Proliferative and matrix synthesis response of canine anterior cruciate ligament fibroblasts submitted to combined growth factors. J Orthop Res 14, 200, 1996.
    • (1996) J Orthop Res , vol.14 , pp. 200
    • Desrosiers, E.A.1    Yahia, L.2    Rivard, C.-H.3
  • 70
    • 53549114786 scopus 로고    scopus 로고
    • Chemotaxis of human articular chondrocytes and mesenchymal stem cells
    • Mishima, Y., and Lotz, M. Chemotaxis of human articular chondrocytes and mesenchymal stem cells. J Orthop Res 26, 1407, 2008.
    • (2008) J Orthop Res , vol.26 , pp. 1407
    • Mishima, Y.1    Lotz, M.2
  • 71
    • 0027997094 scopus 로고
    • Platelet-derived growth factor-BB stimulates synthesis of the integrin [alpha]2-subunit in human diploid fibroblasts
    • Ahlén, K., and Rubin, K. Platelet-derived growth factor-BB stimulates synthesis of the integrin [alpha]2-subunit in human diploid fibroblasts. Exp Cell Res 215, 347, 1994.
    • (1994) Exp Cell Res , vol.215 , pp. 347
    • Ahlén, K.1    Rubin, K.2
  • 72
    • 0029860547 scopus 로고    scopus 로고
    • Platelet-derived growth factor and inflammatory cytokines have differential effects on the expression of integrins alpha 1 beta 1 and alpha 5 beta 1 by human dermal fibroblasts in vitro
    • Gailit, J., Xu, J., Bueller, H., and Clark, R. Platelet-derived growth factor and inflammatory cytokines have differential effects on the expression of integrins alpha 1 beta 1 and alpha 5 beta 1 by human dermal fibroblasts in vitro. J Cell Physiol 169, 281, 1996.
    • (1996) J Cell Physiol , vol.169 , pp. 281
    • Gailit, J.1    Xu, J.2    Bueller, H.3    Clark, R.4
  • 73
    • 0026777480 scopus 로고
    • Regulation of vascular smooth muscle cell integrin expression by transforming growth factor beta1 and by platelet-derived growth factor-BB
    • Janat, M., Argraves, W., and Liau, G. Regulation of vascular smooth muscle cell integrin expression by transforming growth factor beta1 and by platelet-derived growth factor-BB. J Cell Physiol 151, 588, 1992.
    • (1992) J Cell Physiol , vol.151 , pp. 588
    • Janat, M.1    Argraves, W.2    Liau, G.3
  • 74
    • 0028978783 scopus 로고
    • Induction of beta 1 integrin synthesis by recombinant platelet-derived growth factor (PDGF-AB) correlates with an enhanced migratory response of human dermal fibroblasts to various extracellular matrix proteins
    • Kirchberg, K., Lange, T., Klein, E., Jungtä ubl, H., Heinen, G., Meyer-Ingold, W., et al. Induction of beta 1 integrin synthesis by recombinant platelet-derived growth factor (PDGF-AB) correlates with an enhanced migratory response of human dermal fibroblasts to various extracellular matrix proteins. Exp Cell Res 220, 29, 1995.
    • (1995) Exp Cell Res , vol.220 , pp. 29
    • Kirchberg, K.1    Lange, T.2    Klein, E.3    Jungtäubl, H.4    Heinen, G.5    Meyer-Ingold, W.6
  • 75
    • 0026047499 scopus 로고
    • Epidermal growth factor activation of vinculin and beta 1-integrin gene transcription in quiescent Swiss 3T3 cells. Regulation through a protein kinase C-independent pathway
    • Bellas, R., Bendori, R., and Farmer, S. Epidermal growth factor activation of vinculin and beta 1-integrin gene transcription in quiescent Swiss 3T3 cells. Regulation through a protein kinase C-independent pathway. J Biol Chem 266, 12008, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 12008
    • Bellas, R.1    Bendori, R.2    Farmer, S.3
  • 76
    • 0032692250 scopus 로고    scopus 로고
    • Regulation of avB3 and a5B1 integrin receptors by basic fibroblast growth factor and platelet-derived growth factor-BB in intrasynovial flexor tendon cells
    • Harwood, F., Goomer, R., Gelberman, R., Silva, M., and Amiel, D. Regulation of avB3 and a5B1 integrin receptors by basic fibroblast growth factor and platelet-derived growth factor-BB in intrasynovial flexor tendon cells. Wound Repair Regen 7, 381, 1999.
    • (1999) Wound Repair Regen , vol.7 , pp. 381
    • Harwood, F.1    Goomer, R.2    Gelberman, R.3    Silva, M.4    Amiel, D.5
  • 77
    • 0030023905 scopus 로고    scopus 로고
    • Extracellular matrix alters PDGF regulation of integrins
    • Xu, J., and Clark, R. Extracellular matrix alters PDGF regulation of integrins. J Biol Chem 132, 239, 1996.
    • (1996) J Biol Chem , vol.132 , pp. 239
    • Xu, J.1    Clark, R.2
  • 78
    • 33746902029 scopus 로고    scopus 로고
    • Supplementation-time dependence of growth factors in promoting tendon healing
    • Chan, B.P., Fu, S.C., Qin, L., Rolf, C., and Chan, K.M. Supplementation-time dependence of growth factors in promoting tendon healing. Clin Orthop Relat Res 448, 240, 2006.
    • (2006) Clin Orthop Relat Res , vol.448 , pp. 240
    • Chan, B.P.1    Fu, S.C.2    Qin, L.3    Rolf, C.4    Chan, K.M.5
  • 79
    • 33748755977 scopus 로고    scopus 로고
    • Effects of platelet-derived growth factor-BB on the metabolic function and morphologic features of equine tendon in explant culture
    • Haupt, J.L., Donnelly, B.P., and Nixon, A.J. Effects of platelet-derived growth factor-BB on the metabolic function and morphologic features of equine tendon in explant culture. Am J Vet Res 67, 1595, 2006.
    • (2006) Am J Vet Res , vol.67 , pp. 1595
    • Haupt, J.L.1    Donnelly, B.P.2    Nixon, A.J.3
  • 80
    • 34848925117 scopus 로고    scopus 로고
    • ACL reconstruction in a rabbit model using irradiated Achilles allograft seeded with mesenchymal stem cells or PDGF-B gene-transfected mesenchymal stem cells
    • Li, F., Jia, H., and Yu, C. ACL reconstruction in a rabbit model using irradiated Achilles allograft seeded with mesenchymal stem cells or PDGF-B gene-transfected mesenchymal stem cells. Knee Surg Sports Traumatol Arthrosc 15, 1219, 2007.
    • (2007) Knee Surg Sports Traumatol Arthrosc , vol.15 , pp. 1219
    • Li, F.1    Jia, H.2    Yu, C.3
  • 81
    • 0031665826 scopus 로고    scopus 로고
    • Early biological effect of in vivo gene transfer of platelet-derived growth factor (PDGF)-B into healing patellar ligament
    • Nakamura, N., Shino, K., Natsuume, T., Horibe, S., Matsumoto, N., Kaneda, Y., et al. Early biological effect of in vivo gene transfer of platelet-derived growth factor (PDGF)-B into healing patellar ligament. Gene Ther 5, 1165, 1998.
    • (1998) Gene Ther , vol.5 , pp. 1165
    • Nakamura, N.1    Shino, K.2    Natsuume, T.3    Horibe, S.4    Matsumoto, N.5    Kaneda, Y.6
  • 82
    • 0035985789 scopus 로고    scopus 로고
    • The vasculature and its role in the damaged and healing tendon
    • Fenwick, S., Hazleman, B., and Riley, G. The vasculature and its role in the damaged and healing tendon. Arthritis Res 4, 252, 2002.
    • (2002) Arthritis Res , vol.4 , pp. 252
    • Fenwick, S.1    Hazleman, B.2    Riley, G.3
  • 83
    • 33746869619 scopus 로고    scopus 로고
    • Biology of tendon injury: Healing, modeling and remodeling
    • Sharma, P., and Maffulli, N. Biology of tendon injury: healing, modeling and remodeling. J Musculoskelet Neuronal Interact 6, 181, 2006.
    • (2006) J Musculoskelet Neuronal Interact , vol.6 , pp. 181
    • Sharma, P.1    Maffulli, N.2
  • 84
    • 0032973230 scopus 로고    scopus 로고
    • Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact
    • Hirschi, K., Rohovsky, S., Beck, L., Smith, S., and D'Amore, P. Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact. Circ Res 84, 298, 1999.
    • (1999) Circ Res , vol.84 , pp. 298
    • Hirschi, K.1    Rohovsky, S.2    Beck, L.3    Smith, S.4    D'Amore, P.5
  • 85
    • 0028355888 scopus 로고
    • PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors
    • Battegay, E., Rupp, J., Iruela-Arispe, L., Sage, E., and Pech, M. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors. J Cell Biol 125, 917, 1994.
    • (1994) J Cell Biol , vol.125 , pp. 917
    • Battegay, E.1    Rupp, J.2    Iruela-Arispe, L.3    Sage, E.4    Pech, M.5
  • 87
    • 80955178835 scopus 로고    scopus 로고
    • PDGF in bone formation and regeneration: New insights into a novel mechanism involving MSCs
    • Caplan, A., and Correa, D. PDGF in bone formation and regeneration: new insights into a novel mechanism involving MSCs. J Orthop Res 29, 1795, 2011.
    • (2011) J Orthop Res , vol.29 , pp. 1795
    • Caplan, A.1    Correa, D.2
  • 88
    • 2642683513 scopus 로고    scopus 로고
    • The synergistic activity of alphavbeta3 integrin and PDGF receptor increases cell migration
    • Woodard, A., García-Cardeñ a, G., Leong, M., Madri, J., Sessa, W., and Languino, L. The synergistic activity of alphavbeta3 integrin and PDGF receptor increases cell migration. J Cell Sci 111, 469, 1998.
    • (1998) J Cell Sci , vol.111 , pp. 469
    • Woodard, A.1    García-Cardeña, G.2    Leong, M.3    Madri, J.4    Sessa, W.5    Languino, L.6
  • 89
    • 0031834239 scopus 로고    scopus 로고
    • A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin, L.E., Hemo, I., and Keshet, E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125, 1591, 1998.
    • (1998) Development , vol.125 , pp. 1591
    • Benjamin, L.E.1    Hemo, I.2    Keshet, E.3
  • 91
    • 77955895442 scopus 로고    scopus 로고
    • PDGF and bFGF modulate tube formation in adipose tissue-derived stem cells
    • Keerl, S., Gehmert, S., Gehmert, S., Song, Y.-H., and Alt, E. PDGF and bFGF modulate tube formation in adipose tissue-derived stem cells. Ann Plast Surg 64, 487, 2010.
    • (2010) Ann Plast Surg , vol.64 , pp. 487
    • Keerl, S.1    Gehmert, S.2    Gehmert, S.3    Song, Y.-H.4    Alt, E.5
  • 92
    • 72449198945 scopus 로고    scopus 로고
    • Plateletderived growth factor receptors regulate mesenchymal cell fate: Implications for neovascularization
    • Ball, S.G., Schuttleworth, C.A., and Kielty, C.M. Plateletderived growth factor receptors regulate mesenchymal cell fate: implications for neovascularization. Expert Opin Biol Ther 10, 57, 2010.
    • (2010) Expert Opin Biol Ther , vol.10 , pp. 57
    • Ball, S.G.1    Schuttleworth, C.A.2    Kielty, C.M.3
  • 93
    • 0028100605 scopus 로고
    • Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells whereas hypoxia upregulates VEGF expression only
    • Brogi, E., Wu, T., Namiki, A., and Isner, J.M. Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells. Whereas hypoxia upregulates VEGF expression only. Circulation 90, 649, 1994.
    • (1994) Circulation , vol.90 , pp. 649
    • Brogi, E.1    Wu, T.2    Namiki, A.3    Isner, J.M.4
  • 94
    • 0142025875 scopus 로고    scopus 로고
    • Hypoxia and PDGF have a synergistic effect that increases the expression of the angiogenic peptide vascular endothelial growth factor in Achilles tendon fibroblasts
    • Petersen, W., Pufe, T., Zantop, T., Tillmann, B., and Mentlein, R. Hypoxia and PDGF have a synergistic effect that increases the expression of the angiogenic peptide vascular endothelial growth factor in Achilles tendon fibroblasts. Arch Orthop Trauma Surg 123, 485, 2003.
    • (2003) Arch Orthop Trauma Surg , vol.123 , pp. 485
    • Petersen, W.1    Pufe, T.2    Zantop, T.3    Tillmann, B.4    Mentlein, R.5
  • 96
    • 0036433229 scopus 로고    scopus 로고
    • PDGF(BB) increases myocardial production of VEGF: Shift in VEGF mRNA splice variants after direct injection of bFGF, PDGF(BB), and PDGF(AB)
    • Affleck, D.G., Bull, D.A., Bailey, S.H., Albanil, A., Connors, R., Stringham, J.C., et al. PDGF(BB) increases myocardial production of VEGF: shift in VEGF mRNA splice variants after direct injection of bFGF, PDGF(BB), and PDGF(AB). J Surg Res 107, 203, 2002.
    • (2002) J Surg Res , vol.107 , pp. 203
    • Affleck, D.G.1    Bull, D.A.2    Bailey, S.H.3    Albanil, A.4    Connors, R.5    Stringham, J.C.6
  • 97
    • 0021216774 scopus 로고
    • Platelet-derived growth factor in vivo: Levels, activity, and rate of clearance
    • Bowen-Pope, D.F. Platelet-derived growth factor in vivo: levels, activity, and rate of clearance. Blood 64, 458, 1984.
    • (1984) Blood , vol.64 , pp. 458
    • Bowen-Pope, D.F.1
  • 99
    • 0025834986 scopus 로고
    • The effects of shortterm application of a combination of platelet-derived and insulin-like growth factors on periodontal wound healing
    • Lynch, S.E., Castilla GRd, Williams, R.C., Kiritsy, C.P., Howell, H., Reddy, M.S., et al. The effects of shortterm application of a combination of platelet-derived and insulin-like growth factors on periodontal wound healing. J Periodontol 62, 458, 1991.
    • (1991) J Periodontol , vol.62 , pp. 458
    • Lynch, S.E.1    Grd, C.2    Williams, R.C.3    Kiritsy, C.P.4    Howell, H.5    Reddy, M.S.6
  • 100
    • 0030250521 scopus 로고    scopus 로고
    • Influence of dosage and timing of application of platelet-derived growth factor on early healing of the rat medial collateral ligament
    • Batten, M.L., Hansen, J.C., and Dahners, L.E. Influence of dosage and timing of application of platelet-derived growth factor on early healing of the rat medial collateral ligament. J Orthop Res 14, 736, 1996.
    • (1996) J Orthop Res , vol.14 , pp. 736
    • Batten, M.L.1    Hansen, J.C.2    Dahners, L.E.3
  • 101
    • 33847293855 scopus 로고    scopus 로고
    • The early effects of sustained plateletderived growth factor administration on the functional and structural properties of repaired intrasynovial flexor tendons: An in vivo biomechanic study at 3 weeks in canines
    • Gelberman, R., Thomopoulos, S., Sakiyama-Elbert, S., Das, R., and Silva, M.J. The early effects of sustained plateletderived growth factor administration on the functional and structural properties of repaired intrasynovial flexor tendons: an in vivo biomechanic study at 3 weeks in canines. J Hand Surg Am 32, 373, 2007.
    • (2007) J Hand Surg Am , vol.32 , pp. 373
    • Gelberman, R.1    Thomopoulos, S.2    Sakiyama-Elbert, S.3    Das, R.4    Silva, M.J.5
  • 102
    • 80052553409 scopus 로고    scopus 로고
    • Augmentation of a rotator cuff suture repair using rhPDGF-BB and a type i bovine collagen matrix in an ovine model
    • Hee, C.K., Dines, J.S., Dines, D.M., Roden, C.M., Wisner-Lynch, L.A., Turner, A.S., et al. Augmentation of a rotator cuff suture repair using rhPDGF-BB and a type I bovine collagen matrix in an ovine model. Am J Sports Med 39, 1630, 2011.
    • (2011) Am J Sports Med , vol.39 , pp. 1630
    • Hee, C.K.1    Dines, J.S.2    Dines, D.M.3    Roden, C.M.4    Wisner-Lynch, L.A.5    Turner, A.S.6
  • 103
    • 78049361323 scopus 로고    scopus 로고
    • The effect of recombinant human plateletderived growth factor BB-coated sutures on rotator cuff healing in a sheep model
    • Uggen, C., Dines, J., McGarry, M., Grande, D., Lee, T., and Limpisvasti, O. The effect of recombinant human plateletderived growth factor BB-coated sutures on rotator cuff healing in a sheep model. Arthroscopy 26, 1456, 2010.
    • (2010) Arthroscopy , vol.26 , pp. 1456
    • Uggen, C.1    Dines, J.2    McGarry, M.3    Grande, D.4    Lee, T.5    Limpisvasti, O.6
  • 104
    • 0028063663 scopus 로고
    • The effect of combinations of growth factors on ligament healing
    • Letson, A.K., and Dahners, L.E. The effect of combinations of growth factors on ligament healing. Clin Orthop Relat Res 308, 207, 1994.
    • (1994) Clin Orthop Relat Res , vol.308 , pp. 207
    • Letson, A.K.1    Dahners, L.E.2
  • 105
    • 0031820226 scopus 로고    scopus 로고
    • The effects of platelet-derived growth factor-BB on healing of the rabbit medial collateral ligament: An in vivo study
    • Hildebrand, K.A., Woo, S.L.Y., Smith, D.W., Allen, C.R., Deie, M., Taylor, B.J., et al. The effects of platelet-derived growth factor-BB on healing of the rabbit medial collateral ligament: an in vivo study. Am J Sports Med 26, 549, 1998.
    • (1998) Am J Sports Med , vol.26 , pp. 549
    • Hildebrand, K.A.1    Woo, S.L.Y.2    Smith, D.W.3    Allen, C.R.4    Deie, M.5    Taylor, B.J.6
  • 106
    • 2442677986 scopus 로고    scopus 로고
    • The influence of locally applied platelet-derived growth factor-BB on free tendon graft remodeling after anterior cruciate ligament reconstruction
    • Weiler, A., Forster, C., Hunt, P., Falk, R., Jung, T., Unterhauser, F.N., et al. The influence of locally applied platelet-derived growth factor-BB on free tendon graft remodeling after anterior cruciate ligament reconstruction. Am J Sports Med 32, 881, 2004.
    • (2004) Am J Sports Med , vol.32 , pp. 881
    • Weiler, A.1    Forster, C.2    Hunt, P.3    Falk, R.4    Jung, T.5    Unterhauser, F.N.6
  • 109
    • 77952293567 scopus 로고    scopus 로고
    • Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles
    • Suwalski, A., Dabboue, H., Delalande, A., Bensamoun, S., Canon, F., Midoux, P., et al. Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles. Biomaterials 31, 5237, 2010.
    • (2010) Biomaterials , vol.31 , pp. 5237
    • Suwalski, A.1    Dabboue, H.2    Delalande, A.3    Bensamoun, S.4    Canon, F.5    Midoux, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.