The synergistic activity of α(v)β3 integrin and PDGF receptor increases cell migration

Journal of Cell Science

Volumn 111, Issue 4, 1998, Pages 469-478

  Woodard, Amy S ^a   García Cardeña, Guillermo ^a   Leong, Margaret ^a   Madri, Joseph A ^a   Sessa, William C ^a   Languino, Lucia R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Integrin; Migration; Platelet derived growth factor receptor

Indexed keywords

INTEGRIN; LAMININ; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR RECEPTOR; VITRONECTIN; ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; CD51 ANTIGEN; LEUKOCYTE ANTIGEN; OLIGOPEPTIDE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PLATELET-DERIVED GROWTH FACTOR BB; VITRONECTIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL STRAIN 3T3; ENDOTHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL ADHESION; CELL CULTURE; CELL DIVISION; CELL MOTION; CYTOLOGY; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; RAT; VASCULAR ENDOTHELIUM;

3T3 CELLS; ANIMALS; ANTIGENS, CD; CELL ADHESION; CELL DIVISION; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMANS; INTEGRIN ALPHAV; LAMININ; MICE; OLIGOPEPTIDES; PLATELET-DERIVED GROWTH FACTOR; RATS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RECEPTORS, VITRONECTIN; VITRONECTIN;

EID: 2642683513     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Bar, R. S., Boes, M., Booth, B. A., Dake, B. L., Henley, S. and Hart, M. N. (1989). The effects of platelel-derived growth factor in cultured microvessel endothelial cells. Endocrinology 124, 1841-1848.
2. 3 integrin associates with a 190-kDa protein that is phosphorylated on tyrosine in response to platelet-derived growth factor. J. Biol. Chem. 268, 17270-17276.
3. Beitz, J. G., Kim, I.-S., Calabresi, P. and Frackelton, A. R. Jr (1991). Human microvascular endothelial cells express receptors for platelet-derived growth factor. Proc. Nat. Acad. Sci. USA 88, 2021-2025.
4. 3 for angiogenesis. Science 264, 569-571.
5. 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels, Cell 79, 1157-1164.
6. 3 blocks human breast cancer growth and angiogenesis in human skin. J. Clin. Invest. 96, 1815-1822.
7. Cary, L. A., Chang, J. F. and Guan, J.-L. (1996). Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J. Cell Sci. 109, 1787-1794.
8. Cheng, Y. F. and Kramer, R. H. (1989). Human microvascular endothelial cells express integrin-related complexes that mediate adhesion to the extracellular matrix. J. Cell. Physiol. 139, 275-286.
9. Claesson-Welsh, L. (1996). Mechanism of action of platelet-derived growth factor. Int. J. Biochem. Cell Biol. 28, 373-385.
10. 3 integrins have different roles in the adhesion and migration of vascular smooth muscle cells on extracellular matrix. Exp. Cell Res. 200, 272-284.
11. Damsky, C. H. and Werb, Z. (1992). Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information. Curr. Opin. Cell Biol. 4, 772-781.
12. Felding-Habermann, B. and Cheresh, D. A. (1993). Vitronectin and its receptors. Curr. Opin. Cell Biol. 5, 864-868.
13. Fitzgerald, L. A., Steiner, B., Rall, S. C. Jr, Lo, S.-S. and Phillips, D. R. (1987). Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone: identity with platelet glycoprotein IIIa and similarity to 'integrin'. J. Biol. Chem. 262, 3936-3939.
14. 1C cytoplasmic domain regulates cell proliferation. J. Biol. Chem. 270, 24666-24669.
15. Fox, P. L. and DiCorleto, P. E. (1991). Endothelial cell production of platelet-derived growth factor. Semin. Perinatol. 15, 34-39.
16. 2 integrins. Science 270, 1500-1502.
17. Gamble, J. R., Matthias, L. J., Meyer, G., Kaur, P., Russ, G., Faull, R., Berndt, M. C. and Vadas, M. A. (1993). Regulation of in vitro capillary tube formation by anti-integrin antibodies. J. Cell Biol. 121, 931-943.
18. Gilmore, A. P. and Romer, L. H. (1996). Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol. Biol. Cell 7, 1209-1224.
19. Hermansson, M., Nistér, M., Betsholtz, C., Heldin, C.-H., Westermark, B. and Funa, K. (1988). Endothelial cell hyperplasia in human glioblastoma: Coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation. Proc. Nat. Acad. Sci. USA 85, 7748-7752.
20. Hynes, R. O. (1992). Integrins: versatility modulation and signaling in cell adhesion. Cell 69, 11-25.
21. Illć. D., Furuta, Y., Kanazawa, S., Takeda, N., Sobue, K., Nakatsuji, N., Nomura, S., Fujimoto, J., Okada, M., Yamamoto, T. and Alzawa, S. (1995). Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 377, 539-543.
22. Juliano, R. L. (1996). Cooperation between soluble factors and integrin-mediated cell anchorage in the control of cell growth and differentiation. BioEssays 18, 911-917.
23. Klein, S., Giancotti, F. G., Presta, M., Albelda, S. M., Buck, C. A. and Rifkin, D. B. (1993). Basic fibroblast growth factor modulates integrin expression in microvascular endothelial cells. Mol. Biol. Cell 4, 973-982.
24. 1 integrin as a laminin receptor. J. Cell Biol. 109, 2455-2462.
25. Languino, L. R., Plescia, J., Duperray, A., Brian, A. A., Plow, E. F., Geltosky, J. E. and Altieri, D. C. (1993). Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1 dependent pathway. Cell 73, 1423-1434.
26. 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. J. Cell Biol. 121, 163-170.
27. Lewis, J. M., Cheresh, D. A. and Schwartz, M. A. (1996). Protein kinase C regulates αvβ5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation. J. Cell Biol. 134, 1323-1332.
28. Lin, T. H., Rosales, C., Mondal, K., Bolen, J. B., Haskill, S. and Juliano, R. L. (1995). Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. J. Biol. Chem. 270, 16189-16197.
29. Madri, J. A. and Williams, S. K. (1983). Capillary endothelial cell cultures: phenotypic modulation by matrix components. J. Cell Biol. 97, 153-165.
30. Madri, J. A., Sankar, S. and Romanic, A. M. (1996). Angiogenesis. In The Molecular and Cellular Biology of Wound Repair (ed. R. A. F. Clark). pp. 355-371. Plenum Press, New York.
31. Marx, M., Perlmutter, R. A. and Madri, J. A. (1994). Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis. J. Clin. Invest. 93, 131-139.
32. Miyamoto, S., Teramoto, H., Gutkind, J. S. and Yamada, K. M. (1996). Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors. J. Cell Biol. 135, 1633-1642.
33. Nicosia, R. F., Nicosia, S. V. and Smith, M. (1994). Vascular endothelial growth factor, platelet-derived growth factor, and insulin-like growth factor-1 promote rat aortic angiogenesis in vitro. Am. J. Pathol. 145, 1023-1029.
34. FAK in the focal adhesion. Int. Rev. Cytol. 167, 161-183.
35. Pasquale, E. B., Maher, P. A. and Singer, S. J. (1988). Comparative study of the tyrosine phosphorylation of proteins in Swiss 3T3 fibroblasts stimulated by a variety of mitogenic agents. J. Cell. Physiol. 137, 146-156.
36. Plate, K. H., Breier, G., Farrell, C. L. and Risau, W. (1992). Platelet-derived growth factor receptor-β is induced during tumor development and upregulated during tumor progression in endothelial cells in human gliomas. Lab. Invest. 67, 529-534.
37. Preissner, K. T., Anders, E., Grulich-Henn, J. and Muller-Berghaus, G. (1988). Attachment of cultured human endothelial cells is promoted by specific association with S protein (vitronectin) as well as with the ternary S protein-thrombin-antithrombin III complex. Blood 71, 1581-1589.
38. Preissner, K. T. (1991). Structure and biological role of vitronectin. Annu. Rev. Cell Biol. 7, 275-310.
39. FAK) and paxillin tyrosine phosphorylation in Swiss 3T3 cells. J. Biol. Chem. 269, 704-710.
40. Ridley, A. J. and Hall, A. (1992). The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.
41. Risau, W., Drexler, H., Mironov, V., Smits, A., Siegbahn, A., Funa, K. and Heldin, C.-H. (1992). Platelet-derived growth factor is angiogenic in vivo. Growth Factors 7, 261-266.
42. Ruoslahti, E. and Reed, J. C. (1994). Anchorage dependence, integrins and apoptosis. Cell 77, 477-478.
43. FAK phosphorylation. Am. J. Pathol. 147, 601-608.
44. 3 integrin associates with activated insulin and PDGFβ receptors and potentiates the biological activity of PDGF. EMBO J. 16, 5600-5607.
45. Schwartz, M. A., Schaller, M. D. and Ginsberg, M. H. (1995). Integrins: emerging paradigms of signal transduction. Annu. Rev. Cell Dev. Biol. 11, 549-599.
46. 3 integrin, osteopontin, and thrombin. Am. J. Pathol. 149, 293-305.
47. Smits, A., Hermansson, M., Nistér, M., Karnushina, I., Heldin, C.-H., Westermark, B. and Funa, K. (1989). Rat brain capillary endothelial cells express functional PDGF B-type receptors. Growth Factors 2, 1-8.
48. Streeten, E. A., Ornberg, R., Curcio, F., Sakaguchi, K., Marx, S., Aurbach, G. D. and Brandi, M. L. (1989). Cloned endothelial cells from fetal bovine bone. Proc. Nat. Acad. Sci. USA 86, 916-920.
49. 3 cytoplasmic domain in triggering focal adhesion kinase phosphorylation. J. Biol. Chem. 272, 7892-7898.
50. Vernon, R. B. and Sage, E. H. (1995). Between molecules and morphology: extracellular matrix and creation of vascular form. Am. J. Pathol. 147, 873-883.
51. Wei, Y., Waltz, D. A., Rao, N., Drummond, R. J., Rosenberg, S. and Chapman, H. A. (1994). Identification of the urokinase receptor as an adhesion receptor for vitronectin. J. Biol. Chem. 269, 32380-32388.