Nucleotide structure of equine platelet-derived growth factor-A and -B and expression in horses with induced acute tendinitis

American Journal of Veterinary Research

Volumn 67, Issue 7, 2006, Pages 1218-1225

  Donnelly, Brandon P ^a   Nixon, Alan J ^a   Haupt, Jennifer L ^a   Dahlgren, Linda A ^a,b  

^a Department of Molecular Biology and Genetics   (United States)

^b VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; FEMALE; FLEXOR TENDON; GENE EXPRESSION; GENE LOCATION; GENE STRUCTURE; HORSE DISEASE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARACRINE SIGNALING; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION; RNA ISOLATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; SYNOVIUM; TENDINITIS; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; COLLAGENASES; GENE EXPRESSION REGULATION; HORSE DISEASES; HORSES; MOLECULAR SEQUENCE DATA; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-SIS; RNA, MESSENGER; TENDINOPATHY;

ANIMALIA; EQUIDAE; EQUUS CABALLUS;

EID: 33747603714     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.67.7.1218     Document Type: Article

References (26)

1. Birch HL, Bailey AJ, Goodship AE. Macroscopic 'degeneration' of equine superficial digital flexor tendon is accompanied by a change in extracellular matrix composition. Equine Vet J 1998;30:534-539.
2. Goodship AE, Birch HL, Wilson AM. The pathobiology and repair of tendon and ligament injury. Vet Clin North Am Equine Pract 1994;10:323-349.
3. Pool RR. Pathologic changes in tendinitis of athletic horses. In: Rantanen NW, Hauser ML, eds. Proceedings of the Dubai 1st International Equine Symposium. The equine athlete: tendon, ligament and soft tissue injuries. Dubai, United Arab Emirates: Matthew R. Rantanen Design, 1996;109-117.
4. Goodship AE, Birch HL. The pathophysiology of the flexor tendons in the equine athlete. In: Rantanen NW, Hauser ML, eds. Proceedings of the Dubai 1st International Equine Symposium. The equine athlete: tendon, ligament and soft tissue injuries. Dubai, United Arab Emirates: Matthew R. Rantanen Design, 1996;83-107.
5. Molloy T, Wang Y, Murrell G. The roles of growth factors in tendon and ligament healing. Sports Med 2003;33:381-394.
6. Alberts B, Bray D, Lewis J, et al. In: Molecular biology of the cell. New York: Garland Publishing, 1983;692-708.
7. Deuel TF, Kawahara RS, Mustoe TA, et al. Growth factors and wound healing: platelet-derived growth factor as a model cytokine. Annu Rev Med 1991;42:567-584.
8. Lynch SE, Colvin RB, Antoniades HN. Growth factors in wound healing. Single and synergistic effects on partial thickness porcine skin wounds. J Clin Invest 1989;84:640-646.
9. Pierce GF, Mustoe TA, Lingelbach J, et al. Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms. J Cell Biol 1989;109:429-440.
10. Hart CE, Forstrom JW, Kelly JD, et al. Two classes of PDGF receptor recognize different isoforms of PDGF. Science 1988;240:1529-1531.
11. Heldin CH, Johnsson A, Wennergren S, et al. A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains. Nature 1986;319:511-514.
12. Stroobant P, Waterfield MD. Purification and properties of porcine platelet-derived growth factor. EMBO J 1984;3:2963-2967.
13. Lepisto J, Peltonen J, Vaha-Kreula M, et al. Platelet-derived growth factor isoforms PDGF-AA, -AB and -BB exert specific effects on collagen gene expression and mitotic activity of cultured human wound fibroblasts. Biochem Biophys Res Commun 1995;209:393-399.
14. Betsholtz C, Johnsson A, Heldin CH, et al. cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines. Nature 1986;320:695-699.
15. Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci USA 2002;99:16899-16903.
16. Dahlgren LA, Mohammed HO, Nixon AJ. Temporal expression of growth factors and matrix molecules in healing tendon lesions. J Orthop Res 2005;23:84-92.
17. Dahlgren LA, van der Meulen MC, Bertram JE, et al. Insulin-like growth factor-I improves cellular and molecular aspects of healing in a collagenase-induced model of flexor tendinitis. J Orthop Res 2002;20:910-919.
18. Meyer-Ingold W, Eichner W. Platelet-derived growth factor. Cell Biol Int 1995;19:389-398.
19. Hosgood G. Wound healing. The role of platelet-derived growth factor and transforming growth factor beta. Vet Surg 1993;22:490-495.
20. Wahl LM, Wahl SM. Inflammation. In: Cohen IK, Diegelmann RF, Lindblad WJ, eds. Wound healing: biochemical and clinical aspects. Philadelphia: WB Saunders Co, 1992;40-62.
21. Beer HD, Longaker MT, Werner S. Reduced expression of PDGF and PDGF receptors during impaired wound healing. J Invest Dermatol 1997;109:132-138.
22. Zhang F, Liu H, Stile F, et al. Effect of vascular endothelial growth factor on rat Achilles tendon healing. Plast Reconstr Surg 2003;112:1613-1619.
23. Morgan CJ, Pledger WJ. Fibroblast proliferation. In: Cohen IK, Diegelmann RF, Lindblad WJ, eds. Wound healing: biochemical and clinical aspects. Philadelphia: WB Saunders Co, 1992;63-76.
24. Bhandari B, Grandaliano G, Abboud HE. Platelet-derived growth factor (PDGF) BB homodimer regulates PDGF A- and PDGF B-chain gene transcription in human mesangial cells. Biochem J 1994;297:385-388.
25. Rydziel S, Canalis E. Expression and growth factor regulation of platelet-derived growth factor B transcripts in primary osteoblast cell cultures. Endocrinology 1996;137:4115-4119.
26. Lynch SE, Nixon JC, Calvin RB, et al. Role of platelet-derived growth factor in wound healing: synergistic effects with other growth factors. Proc Natl Acad Sci U S A 1987;84:7696-7700.