ACL reconstruction in a rabbit model using irradiated Achilles allograft seeded with mesenchymal stem cells or PDGF-B gene-transfected mesenchymal stem cells

Knee Surgery, Sports Traumatology, Arthroscopy

Volumn 15, Issue 10, 2007, Pages 1219-1227

  Li, Feng ^a   Jia, Hongti ^b   Yu, Changlong ^a  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Allograft; Anterior cruciate ligament; Mesenchymal stem cells; PDGF BB; Retrovirus

Indexed keywords

COBALT; COLLAGEN; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB; UNCLASSIFIED DRUG;

ACHILLES TENDON; ALLOTRANSPLANTATION; ANIMAL; ANIMAL MODEL; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; BIOSYNTHESIS; FEMALE; GENETIC TRANSFECTION; GENETICS; MESENCHYMAL STEM CELL TRANSPLANTATION; PATHOLOGY; RABBIT; RADIATION EXPOSURE; TISSUE ENGINEERING; TRANSPLANTATION; WOUND HEALING;

ACHILLES TENDON; ANIMALS; ANTERIOR CRUCIATE LIGAMENT; COBALT RADIOISOTOPES; COLLAGEN; FEMALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MODELS, ANIMAL; PLATELET-DERIVED GROWTH FACTOR; RABBITS; TISSUE ENGINEERING; TRANSFECTION; TRANSPLANTATION, HOMOLOGOUS; WOUND HEALING;

EID: 34848925117     PISSN: 09422056     EISSN: 14337347     Source Type: Journal    
DOI: 10.1007/s00167-007-0385-x     Document Type: Article

References (33)

1. Arnoczky SP, Warren RF, Ashlock MA (1986) Replacement of the anterior cruciate ligament using a patellar tendon allograft: an experimental study. J Bone Joint Surg Am 68A:376-385
2. Awad HA, Butler DL, Boivin GP, Smith FN, Malaviya P, Huibregtse B, Caplan AI (1999) Autologous mesenchymal stem cell-mediated repair of tendon. Tissue Eng 5:267-277
3. Awad HA, Butler DL, Dressler MR, Smith F, Boivin GP, Young RG (2003) Repair of patellar tendon injuries using mesenchymal stem cells and collagen scaffolds. J Orthop Res 21:420-431
4. Batten ML, Hansen JC, Dahners LE (1996) Influence of dosage and timing of application of platelet-derived growth factor on early healing of the rat medial collateral ligament. J Orthop Res 14:736-741
5. Bellincampi LD, Closkey RF, Prasad R, Zawadsky JP, Dunn MG (1998) Viability of fibroblast-seeded ligament analogs after autogenous implantation. J Orthop Res 16:414-420
6. Bos GD, Goldberg VM, Powell AE, Heiple KG, Zika JM (1984) The effect of histocompatibility matching on canine frozen bone allografts. J Bone Joint Surg Am 65A:89-96
7. Heldin C-H, Westermark B (1999) Mechanism of action and in vivo role of Platelet-derived growth factor. Phys Rev 79:1283-1316
8. DesRosiers EA, Yahia L, Rivard CH (1996) Proliferative and matrix synthesis response of canine anterior cruciate ligament fibroblasts submitted to combined growth factors. J Orthop Res 14:200-208
9. Dunn MG, Liesch JB, Tiku ML, Zawadsky JP (1995) Development of fibroblast-seeded ligament analogs for ACL reconstruction. J Biomed Mater Res 29:1363-1371
10. Friedlaender GE, Strong DM, Sell KW (1976) Studies on the antigenicity of bone: freeze-dried and deep-frozen bone allografts in rabbits. J. Bone Joint Surg Am 58A:854-858
11. Graham WC, Smith PA, McGuire MP (1955) The use of frozen stored tendons for grafting: an experimental study. J Bone Joint Surg Am 37A:624
12. Hildebrand KA, Woo SL, Smith DW, Allen CR, Deie M, Taylor BJ, Schmidt CC (1998) The effects of platelet-derived growth factor-BB on healing of the rabbit medial collateral ligament: an in vivo study. Am J Sports Med 26:549-554
13. Kang HJ, Kang ES (1999) Ideal concentration of growth factors in rabbit's flexor tendon culture. Yonsei Med J 40:26-29
14. Letson AK, Dahners LE (1994) The effect of combinations of growth factors on ligament healing. Clin Orthop Relat Res 308:207-212
15. Lin VS, Lee MC, O'Neal S, McKean J, Sung KL (1999) Ligament tissue engineering using synthetic biodegradable fiber scaffolds. Tissue Eng 5:443-452
16. Meaney Murray M, Rice K, Wright RJ, Spector M (2003) The effect of selected growth factors on human anterior cruciate ligament cell interactions with a three-dimensional collagen-GAG scaffold. J Orthop Res 21:238-244
17. Minami A, Ishii S, Ogino T (1982) The effect of the immunological antigenicity of the allogenic tendinosus tendon grafting. Hand 14:111-119
18. Minguell JJ, Erices A, Conget P (2002) Mesenchymal stem cells. Exp Biol Med 226:507-520
19. Agung M, Ochi M, Yanada S, Adachi N, Izuta Y, Yamasaki T, Toda K (2006) Mobilization of bone marrow-derived mesenchymal stem cells into the injured tissues after intraarticular injection and their contribution to tissue regeneration. Knee Surg Sports Traumatol Arthrosc 14:1307-1314
20. Nakamura N, Shino K, Natsuume T, Horibe S, Matsumoto N, Kaneda Y, Ochi T (1998) Early biological effect of in vivo gene transfer of platelet-derived growth factor (PDGF)-B into healing patellar ligament. Gene Ther 5:1165-1170
21. Peacock EE, Petty J (1960) Antigenicity of tendon. J Surg Gynecol Obstet 110:187-192
22. Peter M, Prokopis, Schepsis AA (1999) Allograft use in ACL reconstruction. Knee 6:75-85
23. Petersen W, Pufe T, Zantop T, Tillmann B, Mentlein R (2003) Hypoxia and PDGF have a synergistic effect that increases the expression of the angiogenetic peptide vascular endothelial growth factor in Achilles tendon fibroblasts. Arch Orthop Trauma Surg 123:485-488
24. Kuroda R, Kurosaka M, Yoshiya S, Mizuno K (2000) Localization of growth factors in the reconstructed anterior cruciate ligament: immunohistological study in dogs. Knee Surg Sports Traumatol Arthrosc 8:120-126
25. Scherping SC Jr, Schmidt CC, Georgescu HI, Kwoh CK, Evans CH, Woo SL (1997) Effect of growth factors on the proliferation of ligament fibroblasts from skeletally mature rabbits. Connect Tissue Res 36:1-8
26. Schmidt CC, Georgescu HI, Kwoh CK, Blomstrom GL, Engle CP, Larkin LA, Evans CH, Woo SL (1995) Effect of growth factors on the proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments. J Orthop Res 13:184-190
27. Spindler KP, Clark SW, Nanney LB, Davidson JM (1996) Expression of collagen and matrix metalloproteinases in ruptured human anterior cruciate ligament: an in situ hybridization study. J Orthop Res 14:857-861
28. Stevenson S, Honn RB, Templeton JW (1983) Effects of tissue antigen matching on the healing of fresh cancellous bone allografts in dogs. Am J Vet Res 44:204-206
29. Van Ei jk F, Saris DB, Riesle J, Willems WJ, Van Blitterswi jk CA, Verbout AJ, Dhert WJ (2004) Tissue engineering of ligaments: a comparison of bone marrow stromal cells, anterior cruciate ligament, and skin fibroblast as cell source. Tissue Eng 10:893-903
30. Wakitani S, Goto T, Pineda SJ, Young RG, Mansour JM, Caplan AI, Goldberg VM (1994) Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage. J Bone Joint Surg Am 76:579-592
31. Watanabe N, Woo SL, Papageorgiou C, Celechovsky C, Takai S (2002) Fate of donor bone marrow cells in medial collateral ligament after simulated autologous transplantation. Microsc Res Tech 58:39-44
32. Yasuhiro Y, Abrahamson S (2000) Dose-related effects of platelet-derived growth factor-BB vary by different rabbit tendons in vitro. Transactions of the 46th annual meeting of the Orthopaedic Research Society
33. Young RG, Butler DL, Weber W, Caplan AI, Gordon SL, Fink DJ (1998) Use of mesenchymal stem cells in a collagen matrix for Achilles tendon repair. J Orthop Res 16:406-413