Novel lipoidal amine-based nanocarrier formulations for siRNA delivery

Therapeutic Delivery

Volumn 3, Issue 6, 2012, Pages 715-723

  Zhou, Chenguang ^a,b   Zhang, Yue ^a,c   Lee, L James ^b   Lee, Robert J ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b The Ohio State University   (United States)

^c NANKAI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AVRIDINE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; NANOCARRIER; SMALL INTERFERING RNA; SORBITAN OLEATE; TOCOFERSOLAN;

ARTICLE; BIOCHEMICAL COMPOSITION; CELL BASED GENE THERAPY; CONTROLLED STUDY; CYTOTOXICITY TEST; DOWN REGULATION; DRUG STRUCTURE; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; IN VITRO GENE TRANSFER; IN VITRO STUDY; INTRACELLULAR TRANSPORT; LIPOSOMAL DELIVERY; LUCIFERASE GENE; NANOANALYSIS; NANOPHARMACEUTICS; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RNA VECTOR; STRUCTURE ANALYSIS;

EID: 84861801328     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.12.47     Document Type: Article

References (32)

1. Bumcrot D, Manoharan M, Koteliansky V et al. RNAi therapeutics: A potential new class of pharmaceutical drugs. Nat. Chem. Biol. 2(12), 711-719 (2006).
2. Palliser D, Chowdhury D, Wang QY et al. An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection. Nature 439(7072), 89-94 (2006).
3. Judge AD, Robbins M, Tavakoli I et al. Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice. J. Clin. Invest. 119(3), 661-673 (2009).
4. Morille M, Passirani C, Vonarbourg A et al. Progress in developing cationic vectors for non-viral systemic gene therapy against cancer. Biomaterials 29(24-25), 3477-3496 (2008).
5. Simoes S, Filipe A, Faneca H et al. Cationic liposomes for gene delivery. Expert Opin. Drug Deliv. 2(2), 237-254 (2005).
6. Love KT, Mahon KP, Levins CG et al. Lipid-like materials for low-dose, in vivo gene silencing. Proc. Natl Acad. Sci. USA 107(5), 1864-1869 (2010).
7. Akinc A, Zumbuehl A, Goldberg M et al. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat. Biotechnol. 26(5), 561-569 (2008).
8. Fatunmbi OO, Newman JA, Sivanandan V et al. Enhancement of antibody response of turkeys to trivalent avian influenza vaccine by positively charged liposomal Avridine adjuvant. Vaccine 10(9), 623-626 (1992).
9. Zhou C, Mao Y, Sugimoto Y et al. SPANosomes as delivery vehicles for small interfering RNA (siRNA). Mol. Pharm. 9(2), 201-210 (2012).
10. Boukany PE, Morss A, Liao WC et al. Nanochannel electroporation delivers precise amounts of biomolecules into living cells. Nat. Nanotechnol. 6(11), 747-754 (2011).
11. Heyes J, Palmer L, Bremner K et al. Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids. J. Control. Release 107(2), 276-287 (2005).
12. Jeffs LB, Palmer LR, Ambegia EG et al. A scalable, extrusion-free method for efficient liposomal encapsulation of plasmid DNA. Pharm. Res. 22(3), 362-372 (2005).
13. Zhou C, Yu B, Yang X et al. Lipid-coated nano-calcium-phosphate (LNCP) for gene delivery. Int. J. Pharm. 392(1-2), 201-208 (2010).
14. Zhou C, Lee LJ, Lee RJ. Cellular pharmacokinetics (PK) and target gene knockdown of surfactant-And lipid-based nanocarriers (NCs) of siRNA. AAPS J. 13(Suppl. 1), Abstract W3028 (2011).
15. Zhang Y, Zhou C, Kwang KJ et al. Efficient siRNA delivery using a polyamidoamine dendrimer with a modified pentaerythritol core. Pharm. Res. 29(6), 1627-1636 (2012).
16. Semple SC, Akinc A, Chen J et al. Rational design of cationic lipids for siRNA delivery. Nat. Biotechnol. 28(2), 172-176 (2010).
17. Ozpolat B, Sood AK, Lopez-Berestein G. Nanomedicine based approaches for the delivery of siRNA in cancer. J. Intern. Med. 267(1), 44-53 (2010).
18. Ma B, Zhang S, Jiang H et al. Lipoplex morphologies and their influences on transfection efficiency in gene delivery. J. Control. Release 123(3), 184-194 (2007).
19. Akhtar S, Benter IF. Nonviral delivery of synthetic siRNAs in vivo. J. Clin. Invest. 117(12), 3623-3632 (2007).
20. Ying B, Campbell R. Optimized formulation for liposomal siRNA delivery to the tumor vasculature. AAPS J. 11(Suppl. 2), Abstract AM2009 (2009).
21. Zhou C, Mao Y, Lee LJ et al. Quantitative analysis of intracellular and cytoplasmic siRNA delivery by SPANosomes. AAPS J. 12(Suppl. 2), Abstract T2073 (2010).
22. Zhang Y, Li H, Sun J et al. DC-Chol/DOPE cationic liposomes: A comparative study of the influence factors on plasmid pDNA and siRNA gene delivery. Int. J. Pharm. 390(2), 198-207 (2010).
23. Vighi E, Leo E, Montanari M et al. Structural investigation and intracellular trafficking of a novel multicomposite cationic solid lipid nanoparticle platform as a pDNA carrier. Therapeutic Delivery 2(11), 1419-1435 (2011).
24. Li SD, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Mol. Pharm. 5(4), 496-504 (2008).
25. Malam Y, Loizidou M, Seifalian AM. Liposomes and nanoparticles: Nanosized vehicles for drug delivery in cancer. Trends Pharmacol. Sci. 30(11), 592-599 (2009).
26. Yim KL, Cunningham D. Targeted drug therapies and cancer. Recent Results Cancer Res. 185, 159-171 (2011).
27. Anderson AO, Wood OL, King AD et al. Studies on anti-viral mucosal immunity with the lipoidal amine adjuvant Avridine. Adv. Exp. Med. Biol. 216B, 1781-1790 (1987).
28. Hughes HP, Campos M, van Drunen Littel-van den Hurk S et al. Multiple administration with interleukin-2 potentiates antigen-specific responses to subunit vaccination with bovine herpesvirus-1 glycoprotein IV. Vaccine 10(4), 226-230 (1992).
29. Berinstein A, Perez Filgueira M, Schudel A et al. Avridine and LPS from Brucella ovis: Effect on the memory induced by foot-And-mouth disease virus vaccination in mice. Vaccine 11(13), 1295-1301 (1993).
30. Rettig GR, Behlke MA. Progress toward in vivo use of siRNAs-II. Mol. Ther. 20, 483-512 (2012).
31. Chen Y, Wu JJ, Huang L. Nanoparticles targeted with NGR motif deliver c-myc siRNA and doxorubicin for anticancer therapy. Mol. Ther. 18(4), 828-834 (2010).
32. Saad M, Garbuzenko OB, Minko T. Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer. Nanomedicine (Lond.) 3(6), 761-776 (2008).