Ethanol extracts of fruiting bodies of Antrodia cinnamomea exhibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways

Phytomedicine

Volumn 19, Issue 8-9, 2012, Pages 768-778

  Chen, Ying Yi ^a   Chou, Pei Yu ^b   Chien, Yi Chung ^b   Wu, Chieh Hsi ^a   Wu, Tian Shung ^a,c   Sheu, Ming Jyh ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Antrodia cinnamomea; Chinese herb; CL1 0; Matrix metalloproteinase; Metastasis; Mushroom

Indexed keywords

ALCOHOL; ANTINEOPLASTIC AGENT; ANTRODIA CINNAMOMEA EXTRACT; GELATIN; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE 1; SYNAPTOPHYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ANTIMIGRATION ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTRODIA CINNAMOMEA; ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; CELL MOTILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; FRUITING BODY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ZYMOGRAPHY;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; ANTRODIA; CELL LINE, TUMOR; CELL MOVEMENT; DEOXYADENOSINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; ERGOSTEROL; ETHANOL; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE 9; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

ANTRODIA CINNAMOMEA; BASIDIOMYCOTA;

EID: 84861793666     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.02.016     Document Type: Article

References (41)

1. Z.H. Ao, Z.H. Xu, Z.M. Lu, H.Y. Xu, X.M. Zhang, and W.F. Dou Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases J Ethnopharmacol 121 2009 194 212
2. I.G. Campbell, S.E. Russell, D.Y. Choong, K.G. Montgomery, M.L. Ciavarella, C.S. Hooi, B.E. Cristiano, R.B. Pearson, and W.A. Phillips Mutation of the PIK3CA gene in ovarian and breast cancer Cancer Res 64 2004 7678 7681
3. M. Canel, P. Secades, M. Garzon-Arango, E. Allonca, C. Suarez, A. Serrels, M. Frame, V. Brunton, and M.D. Chiara Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression Br J Cancer 98 2008 1274 1284
4. L. Chang, and M. Karin Mammalian MAP kinase signalling cascades Nature 410 2001 37 40
5. Y.M. Chang, Y.T. Shih, Y.S. Chen, C.L. Liu, W.K. Fang, C.H. Tsai, F.J. Tsai, W.W. Kuo, T.Y. Lai, and C.Y. Huang Schwann cell migration induced by earthworm extract via activation of PAs and MMP2/9 mediated through ERK1/2 and p38 Evid Based Complement Alternat Med 2011 2011 10.1093/ecam/nep131 Article ID: 395458, 12 pages
6. C.C. Chen, Y.W. Liu, Y.B. Ker, Y.Y. Wu, E.Y. Lai, C.C. Chyau, T.H. Hseu, and R.Y. Peng Chemical characterization and anti-inflammatory effect of polysaccharides fractionated from submerge-cultured Antrodia camphorata mycelia J Agric Food Chem 55 2007 5007 5012
7. K.C. Chen, C.C. Peng, R.Y. Peng, C.H. Su, H.S. Chiang, J.H. Yan, and H.M. Hsieh-Li Unique formosan mushroom Antrodia camphorata differentially inhibits androgen-responsive LNCaP and -independent PC-3 prostate cancer cells Nutr Cancer 57 2007 111 121
8. Y.A. Choi, H.K. Lim, J.R. Kim, C.H. Lee, Y.J. Kim, S.S. Kang, and S.H. Baek Group IB secretory phospholipase A2 promotes matrix metalloproteinase-2- mediated cell migration via the phosphatidylinositol 3-kinase and AKT pathway J Biol Chem 279 2004 36579 36585
9. Y.W. Chu, P.C. Yang, S.C. Yang, Y.C. Shyu, M.J. Hendrix, R. Wu, and C.W. Wu Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line Am J Respir Cell Mol Biol 17 1997 353 360
10. P. Fishman, S. Bar-Yehuda, G. Ohana, S. Pathak, L. Wasserman, F. Barer, and A.S. Multani Adenosine acts as an inhibitor of lymphoma cell growth: a major role for the A3 adenosine receptor Eur J Cancer 36 2000 1452 1458
11. A.K. Gupta, D.E. Soto, M.D. Feldman, J.D. Goldsmith, R. Mick, S.M. Hahn, M. Machtay, R.J. Muschel, and W.G. McKenna Signaling pathways in NSCLC as a predictor of outcome and response to therapy Lung 182 2004 151 162
12. Y.C. Hseu, S.C. Chen, H.C. Chen, J.W. Liao, and H.L. Yang Antrodia camphorata inhibits proliferation of human breast cancer cells in vitro and in vivo Food Chem Toxicol 46 2008 2680 2688
13. Y.L. Hsu, P.L. Kuo, C.Y. Cho, W.C. Ni, T.F. Tzeng, L.T. Ng, Y.H. Kuo, and C.C. Lin Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor kappaB pathway Food Chem Toxicol 45 2007 1249 1257
14. G.J. Huang, C.M. Yang, Y.S. Chang, S. Amagaya, H.C. Wang, W.C. Hou, S.S. Huang, and M.L. Hu Hispolon suppresses SK-Hep1 human hepatoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen activator through the PI3K/AKT and ERK signaling pathways J Agric Food Chem 58 2010 9468 9475
15. C. Hwangbo, J. Kim, J.J. Lee, and J.H. Lee Activation of the integrin effector kinase focal adhesion kinase in cancer cells is regulated by crosstalk between protein kinase Calpha and the PDZ adapter protein mda-9/Syntenin Cancer Res 70 2010 1645 1655
16. A. Jemal, T. Murray, E. Ward, A. Samuels, R.C. Tiwari, A. Ghafoor, E.J. Feuer, and M.J. Thun Cancer statistics, 2005 CA Cancer J Clin 55 2005 10 30
17. B. Kumar, S. Koul, J. Petersen, L. Khandrika, J.S. Hwa, R.B. Meacham, S. Wilson, and H.K. Koul p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity Cancer Res 70 2010 832 841
18. P.T. Kuo, T.P. Lin, L.C. Liu, C.H. Huang, J.K. Lin, J.Y. Kao, and T.D. Way Penta-O-galloyl-beta-d-glucose suppresses prostate cancer bone metastasis by transcriptionally repressing EGF-induced MMP-9 expression J Agric Food Chem 57 2009 3331 3339
19. K.C. Lai, A.C. Huang, S.C. Hsu, C.L. Kuo, J.S. Yang, S.H. Wu, and J.G. Chung Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway J Agric Food Chem 58 2010 2935 2942
20. S.J. Lee, S.K. Kim, W.S. Choi, W.J. Kim, and S.K. Moon Cordycepin causes p21WAF1-mediated G2/M cell-cycle arrest by regulating c-Jun N-terminal kinase activation in human bladder cancer cells Arch Biochem Biophys 490 2009 103 109
21. H.F. Liao, Y.Y. Chen, J.J. Liu, M.L. Hsu, H.J. Shieh, H.J. Liao, C.J. Shieh, M.S. Shiao, and Y.J. Chen Inhibitory effect of caffeic acid phenethyl ester on angiogenesis, tumor invasion, and metastasis J Agric Food Chem 51 2003 7907 7912
22. Y.W. Lin, J.H. Pan, R.H. Liu, Y.H. Kuo, L.Y. Sheen, and B.H. Chiang The 4-acetylantroquinonol B isolated from mycelium of Antrodia cinnamomea inhibits proliferation of hepatoma cells J Sci Food Agric 90 2010 1739 1744
23. K. Lirdprapamongkol, J.P. Kramb, T. Suthiphongchai, R. Surarit, C. Srisomsap, G. Dannhardt, and J. Svasti Vanillin suppresses metastatic potential of human cancer cells through PI3K inhibition and decreases angiogenesis in vivo J Agric Food Chem 57 2009 3055 3063
24. M. Loesch, H.Y. Zhi, S.W. Hou, X.M. Qi, R.S. Li, Z. Basir, T. Iftner, A. Cuenda, and G. Chen p38gamma MAPK cooperates with c-Jun in trans-activating matrix metalloproteinase 9 J Biol Chem 285 2010 15149 15158
25. M.C. Lu, Y.C. Du, J.J. Chuu, S.L. Hwang, P.C. Hsieh, C.S. Hung, F.R. Chang, and Y.C. Wu Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A Arch Toxicol 83 2009 121 129
26. S. Man, W. Gao, Y. Zhang, Z. Liu, L. Yan, L. Huang, and C. Liu Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma Cancer Biol Ther 11 2011 592 598
27. X.N. Meng, Y. Jin, Y. Yu, J. Bai, G.Y. Liu, J. Zhu, Y.Z. Zhao, Z. Wang, F. Chen, K.Y. Lee, and S.B. Fu Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion Br J Cancer 101 2009 327 334
28. K. Nakamura, K. Konoha, N. Yoshikawa, Y. Yamaguchi, S. Kagota, K. Shinozuka, and M. Kunitomo Effect of cordycepin (3′-deoxyadenosine) on hematogenic lung metastatic model mice In Vivo 19 2005 137 141
29. E.M. Noh, J.S. Kim, H. Hur, B.H. Park, E.K. Song, M.K. Han, K.B. Kwon, W.H. Yoo, I.K. Shim, S.J. Lee, H.J. Youn, and Y.R. Lee Cordycepin inhibits IL-1beta-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts Rheumatology (Oxford) 48 2009 45 48
30. M.H. Pan, C.C. Lin, J.K. Lin, and W.J. Chen Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/AKT and mitogen-activated protein kinase cascade signaling J Agric Food Chem 55 2007 5030 5037
31. J.T. Parsons Focal adhesion kinase: the first ten years J Cell Sci 116 2003 1409 1416
32. C.C. Peng, K.C. Chen, R.Y. Peng, C.C. Chyau, C.H. Su, and H.M. Hsieh-Li Antrodia camphorata extract induces replicative senescence in superficial TCC, and inhibits the absolute migration capability in invasive bladder carcinoma cells J Ethnopharmacol 109 2007 93 103
33. K. Shibata, F. Kikkawa, A. Nawa, A.A. Thant, K. Naruse, S. Mizutani, and M. Hamaguchi Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells Cancer Res 58 1998 900 903
34. Y.W. Shih, P.S. Chen, C.H. Wu, Y.F. Jeng, and C.J. Wang Alpha-chaconine-reduced metastasis involves a PI3K/AKT signaling pathway with downregulation of NF-kappaB in human lung adenocarcinoma A549 cells J Agric Food Chem 55 2007 11035 11043
35. Z.T. Tsai, and S.L. Liaw The Use and the Effect of Ganoderma 2010 San Yun Press Taichung, Taiwan pp. 116-117
36. Y.Y. Wong, A. Moon, R. Duffin, A. Barthet-Barateig, H.A. Meijer, M.J. Clemens, and C.H. de Moor Cordycepin inhibits protein synthesis and cell adhesion through effects on signal transduction J Biol Chem 285 2010 2610 2621
37. H. Wu, C.L. Pan, Y.C. Yao, S.S. Chang, S.L. Li, and T.F. Wu Proteomic analysis of the effect of Antrodia camphorata extract on human lung cancer A549 cell Proteomics 6 2006 826 835
38. H.L. Yang, Y.C. Hseu, J.Y. Chen, Y.J. Yech, F.J. Lu, H.H. Wang, P.S. Lin, and B.C. Wang Antrodia camphorata in submerged culture protects low density lipoproteins against oxidative modification Am J Chin Med 34 2006 217 231
39. H.L. Yang, Y.H. Kuo, C.T. Tsai, Y.T. Huang, S.C. Chen, H.W. Chang, E. Lin, W.H. Lin, and Y.C. Hseu Anti-metastatic activities of Antrodia camphorata against human breast cancer cells mediated through suppression of the MAPK signaling pathway Food Chem Toxicol 49 2011 290 298
40. Z.Z. Zeng, Y. Jia, N.J. Hahn, S.M. Markwart, K.F. Rockwood, and D.L. Livant Role of focal adhesion kinase and phosphatidylinositol 3′-kinase in integrin fibronectin receptor-mediated, matrix metalloproteinase-1-dependent invasion by metastatic prostate cancer cells Cancer Res 66 2006 8091 8099
41. Y. Zhang, A.A. Thant, Y. Hiraiwa, Y. Naito, T.T. Sein, Y. Sohara, S. Matsuda, and M. Hamaguchi A role for focal adhesion kinase in hyluronan-dependent MMP-2 secretion in a human small-cell lung carcinoma cell line, QG90 Biochem Biophys Res Commun 290 2002 1123 1127