β-adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction

FASEB Journal

Volumn 26, Issue 6, 2012, Pages 2531-2537

  Chen, Biyi ^a   Li, Yue ^a   Jiang, Shuxia ^a   Xie, Yu Ping ^a   Guo, Ang ^a   Kutschke, William ^a   Zimmerman, Kathy ^b   Weiss, Robert M ^a   Miller, Francis J ^a,b   Anderson, Mark E ^a   Song, Long Sheng ^a  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

AR blockers; Heart failure

Indexed keywords

CARVEDILOL; CAVEOLIN 3; CELL PROTEIN; JUNCTOPHILLIN 2; METOPROLOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG MECHANISM; HEART INFARCTION; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART PERFUSION; ISOLATED HEART; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOPLASMIC RETICULUM; TISSUE STRUCTURE; TRANSVERSE TUBULAR SYSTEM;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CARBAZOLES; CAVEOLIN 3; MALE; MEMBRANE PROTEINS; METOPROLOL; MICE; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PROPANOLAMINES; VENTRICULAR REMODELING;

MURINAE;

EID: 84861782410     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-199505     Document Type: Article

References (45)

1. Epstein, S., Robinson, B. F., Kahler, R. L., and Braunwald, E. (1965) Effects of beta-adrenergic blockade on the cardiac response to maximal and submaximal exercise in man. J. Clin. Invest. 44, 1745-1753
2. Hall, S. A., Cigarroa, C. G., Marcoux, L., Risser, R. C., Grayburn, P. A., and Eichhorn, E. J. (1995) Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade. J. Am. Coll. Cardiol. 25, 1154-1161
3. Janosi, A., Ghali, J. K., Herlitz, J., Czuriga, I., Klibaner, M., Wikstrand, J., and Hjalmarson, A. (2003) Metoprolol CR/XL in postmyocardial infarction patients with chronic heart failure: experiences from MERIT-HF. Am. Heart. J. 146, 721-728 (Pubitemid 37281720)
4. Gheorghiade, M., Colucci, W. S., and Swedberg, K. (2003) Betablockers in chronic heart failure. Circulation 107, 1570-1575
5. Packer, M., Coats, A. J., Fowler, M. B., Katus, H. A., Krum, H., Mohacsi, P., Rouleau, J. L., Tendera, M., Castaigne, A., Roecker, E. B., Schultz, M. K., and DeMets, D. L. (2001) Effect of carvedilol on survival in severe chronic heart failure. N. Engl. J. Med. 344, 1651-1658 (Pubitemid 32479962)
6. Packer, M., Fowler, M. B., Roecker, E. B., Coats, A. J., Katus, H. A., Krum, H., Mohacsi, P., Rouleau, J. L., Tendera, M., Staiger, C., Holcslaw, T. L., Amann-Zalan, I., and DeMets, D. L. (2002) Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study. Circulation 106, 2194-2199 (Pubitemid 35222212)
7. Song, L. S., Guatimosim, S., Gomez-Viquez, L., Sobie, E. A., Ziman, A., Hartmann, H., and Lederer, W. J. (2005) Calcium biology of the transverse tubules in heart. Ann. N. Y. Acad. Sci. 1047, 99-111 (Pubitemid 41123831)
8. 2+ channels and ryanodine receptors in heart cells. Nature 410, 592-596
9. Brette, F., and Orchard, C. (2003) T-tubule function in mammalian cardiac myocytes. Circ. Res. 92, 1182-1192 (Pubitemid 36723645)
10. 2+ channels and the sarcoplasmic reticulum: alterations during cardiac remodelling. Cardiovasc. Res. 77, 315-324
11. Ibrahim, M., Al Masri, A., Navaratnarajah, M., Siedlecka, U., Soppa, G. K., Moshkov, A., Al-Saud, S. A., Gorelik, J., Yacoub, M. H., and Terracciano, C. M. (2010) Prolonged mechanical unloading affects cardiomyocyte excitation-contraction coupling, transverse-tubule structure, and the cell surface. FASEB J. 24, 3321-3329
12. Franzini-Armstrong, C. (1999) The sarcoplasmic reticulum and the control of muscle contraction. FASEB J. 13(Suppl. 2), S266-S270
13. Song, L. S., Wang, S. Q., Xiao, R. P., Spurgeon, H., Lakatta, E. G., and Cheng, H. (2001) beta-Adrenergic stimulation synchronizes intracellular Ca(2+) release during excitation-contraction coupling in cardiac myocytes. Circ. Res. 88, 794-801 (Pubitemid 32429975)
14. Lyon, A. R., MacLeod, K. T., Zhang, Y., Garcia, E., Kanda, G. K., Lab, M. J., Korchev, Y. E., Harding, S. E., and Gorelik, J. (2009) Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart. Proc. Natl. Acad. Sci. U. S. A. 106, 6854-6859
15. Crossman, D. J., Ruygrok, P. N., Soeller, C., and Cannell, M. B. (2011) Changes in the organization of excitation-contraction coupling structures in failing human heart. PLoS One 6, e17901
16. Song, L. S., Sobie, E. A., McCulle, S., Lederer, W. J., Balke, C. W., and Cheng, H. (2006) Orphaned ryanodine receptors in the failing heart. Proc. Natl. Acad. Sci. U. S. A. 103, 4305-4310
17. Louch, W. E., Mork, H. K., Sexton, J., Stromme, T. A., Laake, P., Sjaastad, I., and Sejersted, O. M. (2006) T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction. J. Physiol. 574, 519-533
18. Heinzel, F. R., Bito, V., Biesmans, L., Wu, M., Detre, E., von Wegner, F., Claus, P., Dymarkowski, S., Maes, F., Bogaert, J., Rademakers, F., D'Hooge, J., and Sipido, K. (2008) Remodeling of T-tubules and reduced synchrony of Ca2+ release in myocytes from chronically ischemic myocardium. Circ. Res. 102, 338-346 (Pubitemid 351271654)
19. Xie, Y. P., Chen, B., Sanders, P., Guo, A., Li, Y., Zimmerman, K., Wang, L. C., Weiss, R. M., Grumbach, I. M., Anderson, M. E., and Song, L. S. (2012) Sildenafil prevents and reverses transverse- tubule remodeling and Ca2+ handling dysfunction in right ventricle failure induced by pulmonary artery hypertension. Hypertension 59, 355-362
20. Wu, C. Y., Jia, Z., Wang, W., Ballou, L. M., Jiang, Y. P., Chen, B., Mathias, R. T., Cohen, I. S., Song, L. S., Entcheva, E., and Lin, R. Z. (2011) PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes. PLoS One 6, e24404
21. Brette, F., Despa, S., Bers, D. M., and Orchard, C. H. (2005) Spatiotemporal characteristics of SR Ca(2+) uptake and release in detubulated rat ventricular myocytes. J. Mol. Cell. Cardiol. 39, 804-812 (Pubitemid 41464417)
22. Brette, F., Rodriguez, P., Komukai, K., Colyer, J., and Orchard, C. H. (2004) beta-adrenergic stimulation restores the Ca transient of ventricular myocytes lacking t-tubules. J. Mol. Cell. Cardiol. 36, 265-275 (Pubitemid 38202355)
23. Wei, S., Guo, A., Chen, B., Kutschke, W., Xie, Y. P., Zimmerman, K., Weiss, R. M., Anderson, M. E., Cheng, H., and Song, L. S. (2010) T-tubule remodeling during transition from hypertrophy to heart failure. Circ. Res. 107, 520-531
24. Takeshima, H., Komazaki, S., Nishi, M., Iino, M., and Kangawa, K. (2000) Junctophilins: a novel family of junctional membrane complex proteins. Mol. Cell 6, 11-22
25. Van Oort, R. J., Garbino, A., Wang, W., Dixit, S. S., Landstrom, A. P., Gaur, N., De Almeida, A. C., Skapura, D. G., Rudy, Y., Burns, A. R., Ackerman, M. J., and Wehrens, X. H. (2011) Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice. Circulation 123, 979-988
26. Zhang, R., Khoo, M. S., Wu, Y., Yang, Y., Grueter, C. E., Ni, G., Price, E. E., Thiel, W., Guatimosim, S., Song, L. S., Madu, E. C., Shah, A. N., Vishnivetskaya, T. A., Atkinson, J. B., Gurevich, V. V., Salama, G., Lederer, W. J., Colbran, R. J., and Anderson, M. E. (2005) Calmodulin kinase II inhibition protects against structural heart disease. Nat. Med. 11, 409-417 (Pubitemid 40562331)
27. Erickson, J. R., Joiner, M. L., Guan, X., Kutschke, W., Yang, J., Oddis, C. V., Bartlett, R. K., Lowe, J. S., O'Donnell, S. E., Aykin-Burns, N., Zimmerman, M. C., Zimmerman, K., Ham, A. J., Weiss, R. M., Spitz, D. R., Shea, M. A., Colbran, R. J., Mohler, P. J., and Anderson, M. E. (2008) A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell 133, 462-474 (Pubitemid 351608692)
28. Francis, J., Weiss, R. M., Wei, S. G., Johnson, A. K., and Felder, R. B. (2001) Progression of heart failure after myocardial infarction in the rat. Am. J. Physiol. 281, R1734-R1745
29. Sun, Y. L., Hu, S. J., Wang, L. H., Hu, Y., and Zhou, J. Y. (2005) Effect of beta-blockers on cardiac function and calcium handling protein in postinfarction heart failure rats. Chest 128, 1812-1821 (Pubitemid 41324480)
30. Bartholomeu, J. B., Vanzelli, A. S., Rolim, N. P., Ferreira, J. C., Bechara, L. R., Tanaka, L. Y., Rosa, K. T., Alves, M. M., Medeiros, A., Mattos, K. C., Coelho, M. A., Irigoyen, M. C., Krieger, E. M., Krieger, J. E., Negrao, C. E., Ramires, P. R., Guatimosim, S., and Brum, P. C. (2008) Intracellular mechanisms of specific beta-adrenoceptor antagonists involved in improved cardiac function and survival in a genetic model of heart failure. J. Mol. Cell. Cardiol. 45, 240-249
31. Kemi, O. J., Hoydal, M. A., Macquaide, N., Haram, P. M., Koch, L. G., Britton, S. L., Ellingsen, O., Smith, G. L., and Wisloff, U. (2011) The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts. J. Cell. Physiol. 226, 2235-2243
32. Minetti, C., Bado, M., Broda, P., Sotgia, F., Bruno, C., Galbiati, F., Volonte, D., Lucania, G., Pavan, A., Bonilla, E., Lisanti, M. P., and Cordone, G. (2002) Impairment of caveolae formation and T-system disorganization in human muscular dystrophy with caveolin-3 deficiency. Am. J. Pathol. 160, 265-270 (Pubitemid 34052287)
33. Ratajczak, P., Damy, T., Heymes, C., Oliviero, P., Marotte, F., Robidel, E., Sercombe, R., Boczkowski, J., Rappaport, L., and Samuel, J. L. (2003) Caveolin-1 and -3 dissociations from caveolae to cytosol in the heart during aging and after myocardial infarction in rat. Cardiovasc. Res. 57, 358-369 (Pubitemid 36144214)
34. Maczewski, M., and Mackiewicz, U. (2008) Effect of metoprolol and ivabradine on left ventricular remodelling and Ca2+ handling in the post-infarction rat heart. Cardiovasc. Res. 79, 42-51 (Pubitemid 351881928)
35. Rehsia, N. S., and Dhalla, N. S. (2010) Mechanisms of the beneficial effects of beta-adrenoceptor antagonists in congestive heart failure. Exp. Clin. Cardiol. 15, e86-95
36. Reiken, S., Wehrens, X. H., Vest, J. A., Barbone, A., Klotz, S., Mancini, D., Burkhoff, D., and Marks, A. R. (2003) Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure. Circulation 107, 2459-2466 (Pubitemid 36605229)
37. Wei, S., Chow, L. T., and Sanderson, J. E. (2000) Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction. J. Am. Coll. Cardiol. 36, 276-281 (Pubitemid 30466145)
38. Colucci, W. S., Kolias, T. J., Adams, K. F., Armstrong, W. F., Ghali, J. K., Gottlieb, S. S., Greenberg, B., Klibaner, M. I., Kukin, M. L., and Sugg, J. E. (2007) Metoprolol reverses left ventricular remodeling in patients with asymptomatic systolic dysfunction: the reversal of ventricular remodeling with Toprol-XL (REVERT) trial. Circulation 116, 49-56 (Pubitemid 47016246)
39. Doughty, R. N., Whalley, G. A., Gamble, G., MacMahon, S., and Sharpe, N. (1997) Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. Australia-New Zealand Heart Failure Research Collaborative Group. J. Am. Coll. Cardiol. 29, 1060-1066 (Pubitemid 27149582)
40. Khattar, R. S., Senior, R., Soman, P., van der Does, R., and Lahiri, A. (2001) Regression of left ventricular remodeling in chronic heart failure: comparative and combined effects of captopril and carvedilol. Am. Heart. J. 142, 704-713 (Pubitemid 32900499)
41. Doughty, R. N., Whalley, G. A., Walsh, H. A., Gamble, G. D., Lopez-Sendon, J., and Sharpe, N. (2004) Effects of carvedilol on left ventricular remodeling after acute myocardial infarction: the CAPRICORN Echo Substudy. Circulation 109, 201-206 (Pubitemid 38114140)
42. Landstrom, A. P., Kellen, C. A., Dixit, S. S., van Oort, R. J., Garbino, A., Weisleder, N., Ma, J., Wehrens, X. H., and Ackerman, M. J. (2011) Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calciumhandling. Circ. Heart Fail. 4, 214-223
43. Minamisawa, S., Oshikawa, J., Takeshima, H., Hoshijima, M., Wang, Y., Chien, K. R., Ishikawa, Y., and Matsuoka, R. (2004) Junctophilin type 2 is associated with caveolin-3 and is downregulated in the hypertrophic and dilated cardiomyopathies. Biochem. Biophys. Res. Commun. 325, 852-856 (Pubitemid 39487950)
44. Xu, M., Zhou, P., Xu, S. M., Liu, Y., Feng, X., Bai, S. H., Bai, Y., Hao, X. M., Han, Q., Zhang, Y., and Wang, S. Q. (2007) Intermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy. PLoS Biol. 5, e21
45. Ziman, A. P., Gomez-Viquez, N. L., Bloch, R. J., and Lederer, W. J. (2010) Excitation-contraction coupling changes during postnatal cardiac development. J. Mol. Cell. Cardiol. 48, 379-386