Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling

Circulation: Heart Failure

Volumn 4, Issue 2, 2011, Pages 214-223

  Landstrom, Andrew P ^a   Kellen, Cherisse A ^a   Dixit, Sayali S ^b   Van Oort, Ralph J ^b   Garbino, Alejandro ^b   Weisleder, Noah ^c   Ma, Jianjie ^c   Wehrens, Xander H T ^b   Ackerman, Michael J ^a,d  

^a MAYO GRADUATE SCHOOL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d MAYO CLINIC   (United States)

Author keywords

Calcium; Hypertrophic cardiomyopathy; JPH2; Junctophilin; Ryanodine receptor

Indexed keywords

CALCIUM CHANNEL L TYPE; JUNCTOPHILIN 2; MEMBRANE PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CAFFEINE; JUNCTOPHILIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL SIZE; CELL STRAIN; CHANNEL GATING; CONTROLLED STUDY; DOWN REGULATION; EXCITATION CONTRACTION COUPLING; GENE SILENCING; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; HUMAN; HUMAN TISSUE; HYPERTROPHIC CARDIOMYOPATHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; TISSUE LEVEL; ANIMAL; CALCIUM SIGNALING; CARDIOMEGALY; CASE CONTROL STUDY; CELL CULTURE; CELL MEMBRANE POTENTIAL; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; RNA INTERFERENCE; TIME;

ANIMALS; CAFFEINE; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CARDIOMEGALY; CARDIOMYOPATHY, HYPERTROPHIC; CASE-CONTROL STUDIES; CELL SIZE; CELLS, CULTURED; DOWN-REGULATION; EXCITATION CONTRACTION COUPLING; GENE SILENCING; HUMANS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MICE; MYOCYTES, CARDIAC; RNA INTERFERENCE; SARCOPLASMIC RETICULUM; TIME FACTORS; TRANSFECTION;

EID: 79955930209     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.110.958694     Document Type: Article

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