Metoprolol reverses left ventricular remodeling in patients with asymptomatic systolic dysfunction: The REversal of VEntricular Remodeling with Toprol-XL (REVERT) Trial

Circulation

Volumn 116, Issue 1, 2007, Pages 49-56

  Colucci, Wilson S ^a   Kolias, Theodore J ^b   Adams, Kirkwood F ^c   Armstrong, William F ^b   Ghali, Jalal K ^d   Gottlieb, Stephen S ^e   Greenberg, Barry ^f   Klibaner, Michael I ^g   Kukin, Marrick L ^h   Sugg, Jennifer E ^g  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

^e UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g ASTRAZENECA   (United Kingdom)

^h Columbia University College of Physicians and Surgeons ^*  (United States)

Author keywords

Heart failure; Receptors, adrenergic, beta; Remodeling; Ventricles

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; METOPROLOL SUCCINATE; PLACEBO;

ADULT; AGED; ARTICLE; DIASTOLE; DIZZINESS; DRUG DOSE TITRATION; DRUG WITHDRAWAL; DYSPNEA; ECHOCARDIOGRAPHY; FATIGUE; FEMALE; GENDER; HEART DILATATION; HEART FAILURE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART VENTRICLE REMODELING; HEART VOLUME; HORMONE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; PERIPHERAL EDEMA; PRIORITY JOURNAL; REGRESSION ANALYSIS; SYSTOLE; SYSTOLIC DYSFUNCTION;

ADRENERGIC BETA-ANTAGONISTS; AGED; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BLOOD PRESSURE; CARDIOVASCULAR AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FEMALE; HEART RATE; HUMANS; MALE; METOPROLOL; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; STROKE VOLUME; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 34347361610     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.106.666016     Document Type: Article

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