Prion potency in stem cells biology

Prion

Volumn 6, Issue 2, 2012, Pages 142-146

  Lopes, Marilene H ^a   Santos, Tiago G ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b A C CAMARGO CANCER CENTER   (Brazil)

Author keywords

Differentiation; Embryonic stem cells; Prion; Proliferation; Self renewal; Tissue specific stem cells

Indexed keywords

PRION PROTEIN;

CELL DIFFERENTIATION; CONFERENCE PAPER; CYTOLOGY; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; HEMATOPOIETIC SYSTEM; HUMAN; MUSCLE REGENERATION; NERVOUS SYSTEM; PROTEIN PROTEIN INTERACTION; STEM CELL;

ANIMALS; CELL BIOLOGY; EMBRYONIC DEVELOPMENT; HUMANS; MICE; PRIONS; STEM CELLS;

EID: 84861750243     PISSN: 19336896     EISSN: 1933690X     Source Type: Journal    
DOI: 10.4161/pri.19035     Document Type: Conference Paper

References (67)

1. Linden R, Martins VR, Prado MA, Cammarota M, Izquierdo I, Brentani RR. Physiology of the prion protein. Physiol Rev 2008; 88:673-728; PMID:18391177; http://dx.doi.org/10.1152/physrev.00007.2007.
2. Caughey B, Baron GS. Prions and their partners in crime. Nature 2006; 443:803-10; PMID:17051207; http://dx.doi.org/10.1038/nature05294.
3. Westaway D, Prusiner SB. Conservation of the cellular gene encoding the scrapie prion protein. Nucleic Acids Res 1986; 14:2035-44; PMID:2870469; http://dx.doi.org/10.1093/nar/14.5.2035.
4. Manson J, West JD, Thomson V, McBride P, Kaufman MH, Hope J. The prion protein gene: a role in mouse embryogenesis? Development 1992; 115:117-22; PMID:1353438.
5. Tremblay P, Bouzamondo-Bernstein E, Heinrich C, Prusiner SB, DeArmond SJ. Developmental expression of PrP in the post-implantation embryo. Brain Res 2007; 1139:60-7; PMID:17292334; http://dx.doi.org/10.1016/j.brainres.2006.12. 055.
6. Hajj GN, Santos TG, Cook ZS, Martins VR. Developmental expression of prion protein and its ligands stress-inducible protein 1 and vitronectin. J Comp Neurol 2009; 517:371-84; PMID:19760599; http://dx.doi.org/10.1002/cne.22157.
7. C) in the human forebrain during development. J Neuropathol Exp Neurol 2006; 65:698-706; PMID:16825956; http://dx.doi.org/10.1097/01.jnen.0000228137.10531.72.
8. Büeler H, Fischer M, Lang Y, Bluethmann H, Lipp HP, DeArmond SJ, et al. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 1992; 356:577-82; PMID:1373228; http://dx.doi.org/10.1038/ 356577a0.
9. Manson JC, Clarke AR, Hooper ML, Aitchison L, McConnell I, Hope J. 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol Neurobiol 1994; 8:121-7; PMID:7999308; http://dx.doi.org/10.1007/BF02780662.
10. Hajj GN, Lopes MH, Mercadante AF, Veiga SS, da Silveira RB, Santos TG, et al. Cellular prion protein interaction with vitronectin supports axonal growth and is compensated by integrins. J Cell Sci 2007; 120:1915-26; PMID:17504807; http://dx.doi.org/10.1242/jcs.03459.
11. Collinge J, Whittington MA, Sidle KC, Smith CJ, Palmer MS, Clarke AR, et al. Prion protein is necessary for normal synaptic function. Nature 1994; 370:295-7; PMID:8035877; http://dx.doi.org/10.1038/370295a0.
12. Maglio LE, Perez MF, Martins VR, Brentani RR, Ramirez OA. Hippocampal synaptic plasticity in mice devoid of cellular prion protein. Brain Res Mol Brain Res 2004; 131:58-64; PMID:15530652; http://dx.doi.org/10.1016/j. molbrainres.2004.08.004.
13. Prestori F, Rossi P, Bearzatto B, Lainé J, Necchi D, Diwakar S, et al. Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control. J Neurosci 2008; 28:7091-103; PMID:18614678; http://dx.doi.org/10.1523/ JNEUROSCI.0409-08.2008.
14. Criado JR, Sánchez-Alavez M, Conti B, Giacchino JL, Wills DN, Henriksen SJ, et al. Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons. Neurobiol Dis 2005; 19:255-65; PMID:15837581; http://dx.doi.org/10.1016/j.nbd.2005.01.001.
15. Coitinho AS, Roesler R, Martins VR, Brentani RR, Izquierdo I. Cellular prion protein ablation impairs behavior as a function of age. Neuroreport 2003; 14:1375-9; PMID:12876477.
16. Tobler I, Deboer T, Fischer M. Sleep and sleep regulation in normal and prion protein-deficient mice. J Neurosci 1997; 17:1869-79; PMID:9030645.
17. Tobler I, Gaus SE, Deboer T, Achermann P, Fischer M, Rülicke T, et al. Altered circadian activity rhythms and sleep in mice devoid of prion protein. Nature 1996; 380:639-42; PMID:8602267; http://dx.doi.org/10.1038/ 380639a0.
18. de Almeida CJ, Chiarini LB, da Silva JP, E Silva PM, Martins MA, Linden R. The cellular prion protein modulates phagocytosis and inflammatory response. J Leukoc Biol 2005; 77:238-46; PMID:15539455; http://dx.doi.org/10.1189/jlb. 1103531.
19. Bainbridge J, Walker KB. The normal cellular form of prion protein modulates T cell responses. Immunol Lett 2005; 96:147-50; PMID:15585317; http://dx.doi.org/10.1016/j.imlet.2004.08.006.
20. Shmerling D, Hegyi I, Fischer M, Blättler T, Brandner S, Götz J, et al. Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell 1998; 93:203-14; PMID:9568713; http://dx.doi.org/10.1016/S0092-8674(00)81572-X.
21. Baumann F, Tolnay M, Brabeck C, Pahnke J, Kloz U, Niemann HH, et al. Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J 2007; 26:538-47; PMID:17245436; http://dx.doi.org/10.1038/sj.emboj. 7601510.
22. Li A, Christensen HM, Stewart LR, Roth KA, Chiesa R, Harris DA. Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125. EMBO J 2007; 26:548-58; PMID:17245437; http://dx.doi.org/10. 1038/sj.emboj.7601507.
23. Martins VR, Beraldo FH, Hajj GN, Lopes MH, Lee KS, Prado MM, et al. Prion protein: orchestrating neurotrophic activities. Curr Issues Mol Biol 2010; 12:63-86; PMID:19767651.
24. Málaga-Trillo E, Solis GP, Schrock Y, Geiss C, Luncz L, Thomanetz V, et al. Regulation of embryonic cell adhesion by the prion protein. PLoS Biol 2009; 7:55; PMID:19278297; http://dx.doi.org/10.1371/journal.pbio.1000055.
25. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 292:154-6; PMID:7242681; http://dx.doi.org/10. 1038/292154a0.
26. Smith SK, Charnock-Jones DS, Sharkey AM. The role of leukemia inhibitory factor and interleukin-6 in human reproduction. Hum Reprod 1998; 13:237-43; PMID:9755426.
27. Williams RL, Hilton DJ, Pease S, Willson TA, Stewart CL, Gearing DP, et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 1988; 336:684-7; PMID:3143916; http://dx.doi.org/10.1038/336684a0.
28. Ying QL, Nichols J, Chambers I, Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003; 115:281-92; PMID:14636556; http://dx.doi.org/10.1016/S0092-8674(03)00847-X.
29. Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004; 10:55-63; PMID:14702635; http://dx.doi.org/10.1038/nm979.
30. Niwa H, Burdon T, Chambers I, Smith A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev 1998; 12:2048-60; PMID:9649508; http://dx.doi.org/10.1101/gad.12.13.2048.
31. Matsuda T, Nakamura T, Nakao K, Arai T, Katsuki M, Heike T, et al. STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J 1999; 18:4261-9; PMID:10428964; http://dx.doi.org/10.1093/emboj/18.15.4261.
32. Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, Chambers I, et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998; 95:379-91; PMID:9814708; http://dx.doi.org/10.1016/S0092-8674(00)81769-9.
33. Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000; 24:372-6; PMID:10742100; http://dx.doi.org/10.1038/74199.
34. Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113:631-42; PMID:12787504; http://dx.doi.org/10.1016/S0092-8674(03)00393-3.
35. Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S, et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003; 113:643-55; PMID:12787505; http://dx.doi.org/ 10.1016/S0092-8674(03)00392-1.
36. Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 2003; 17:126-40; PMID:12514105; http://dx.doi.org/10.1101/gad.224503.
37. Cartwright P, McLean C, Sheppard A, Rivett D, Jones K, Dalton S. LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 2005; 132:885-96; PMID:15673569; http://dx.doi.org/10. 1242/dev.01670.
38. Li Y, McClintick J, Zhong L, Edenberg HJ, Yoder MC, Chan RJ. Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. Blood 2005; 105:635-7; PMID:15358627; http://dx.doi.org/10.1182/blood-2004-07-2681.
39. Ralston A, Rossant J. The genetics of induced pluripotency. Reproduction 2010; 139:35-44; PMID:19605512; http://dx.doi.org/10.1530/REP-09-0024.
40. Lee YJ, Baskakov IV. Treatment with normal prion protein delays differentiation and helps to maintain high proliferation activity in human embryonic stem cells. J Neurochem 2010; 114:362-73; PMID:20089130; http://dx.doi.org/10.1111/j.1471-4159.2010.06601.x.
41. C) in differentiating mouse embryonic stem cells. Differentiation 2011; 81:68-77; PMID:20926176; http://dx.doi. org/10.1016/j.diff.2010.09.181.
42. Miranda A, Pericuesta E, Ramírez MA, Gutierrez-Adan A. Prion protein expression regulates embryonic stem cell pluripotency and differentiation. PLoS One 2011; 6:18422; PMID:21483752; http://dx.doi.org/10. 1371/journal.pone.0018422.
43. Huveneers S, Truong H, Danen HJ. Integrins: signaling, disease and therapy. Int J Radiat Biol 2007; 83:743-51; PMID:17852562; http://dx.doi.org/10. 1080/09553000701481808.
44. Hayashi Y, Furue MK, Okamoto T, Ohnuma K, Myoishi Y, Fukuhara Y, et al. Integrins regulate mouse embryonic stem cell self-renewal. Stem Cells 2007; 25:3005-15; PMID:17717067; http://dx.doi.org/10.1634/stemcells.2007-0103.
45. Lee ST, Yun JI, Jo YS, Mochizuki M, van der Vlies AJ, Kontos S, et al. Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely defined niche. Biomaterials 2010; 31:1219-26; PMID:19926127; http://dx.doi.org/10.1016/j.biomaterials.2009.10.054.
46. Hailesellasse Sene K, Porter CJ, Palidwor G, Perez-Iratxeta C, Muro EM, Campbell PA, et al. Gene function in early mouse embryonic stem cell differentiation. BMC Genomics 2007; 8:85; PMID:17394647; http://dx.doi.org/10. 1186/1471-2164-8-85.
47. Faustino RS, Behfar A, Perez-Terzic C, Terzic A. Genomic chart guiding embryonic stem cell cardiopoiesis. Genome Biol 2008; 9:6; PMID:18184438; http://dx.doi.org/10.1186/gb-2008-9-1-r6.
48. Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, et al. Dissecting direct reprogramming through integrative genomic analysis. Nature 2008; 454:49-55; PMID:18509334; http://dx.doi.org/10.1038/nature07056.
49. Hidaka K, Shirai M, Lee JK, Wakayama T, Kodama I, Schneider MD, et al. The cellular prion protein identifies bipotential cardiomyogenic progenitors. Circ Res 2010; 106:111-9; PMID:19910576; http://dx.doi.org/10.1161/CIRCRESAHA. 109.209478.
50. C) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis. Proc Natl Acad Sci USA 2006; 103:3416-21; PMID:16492732; http://dx.doi.org/10.1073/pnas.0511290103.
51. Alvarez-Buylla A, Seri B, Doetsch F. Identification of neural stem cells in the adult vertebrate brain. Brain Res Bull 2002; 57:751-8; PMID:12031271; http://dx.doi. org/10.1016/S0361-9230(01)00770-5.
52. Gage FH. Mammalian neural stem cells. Science 2000; 287:1433-8; PMID:10688783; http://dx.doi. org/10.1126/science.287.5457.1433.
53. C. Brain Res 2007; 1186:65-73; PMID:17996224; http://dx.doi.org/ 10.1016/j.brainres.2007.10.039.
54. Arantes C, Nomizo R, Lopes MH, Hajj GN, Lima FR, Martins VR. Prion protein and its ligand stress inducible protein 1 regulate astrocyte development. Glia 2009; 57:1439-49; PMID:19243016; http://dx.doi.org/10.1002/ glia.20861.
55. Santos TG, Silva IR, Costa-Silva B, Lepique AP, Martins VR, Lopes MH. Enhanced neural progenitor/stem cells self-renewal via the interaction of stress-inducible protein 1 with the prion protein. Stem Cells 2011; 29:1126-36; PMID:21608082; http://dx.doi.org/10.1002/stem.664.
56. Lopes MH, Hajj GN, Muras AG, Mancini GL, Castro RM, Ribeiro KC, et al. Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways. J Neurosci 2005; 25:11330-9; PMID:16339028; http://dx.doi.org/10.1523/JNEUROSCI.2313-05. 2005.
57. Chiarini LB, Freitas AR, Zanata SM, Brentani RR, Martins VR, Linden R. Cellular prion protein transduces neuroprotective signals. EMBO J 2002; 21:3317-26; PMID:12093733; http://dx.doi.org/10.1093/emboj/cdf324.
58. Beraldo FH, Arantes CP, Santos TG, Queiroz NG, Young KF, Rylett RJ, et al. Role of alpha7 nicotinic acetylcholine receptor in calcium signaling induced by prion protein interaction with stress-inducible protein 1. J Biol Chem 2010; 285:36542-50; PMID:20837487; http://dx.doi.org/10.1074/jbc.M110.157263.
59. Coitinho AS, Lopes MH, Hajj GN, Rossato JI, Freitas AR, Castro CC, et al. Short-term memory formation and long-term memory consolidation are enhanced by cellular prion association to stress-inducible protein 1. Neurobiol Dis 2007; 26:282-90; PMID:17329112; http://dx.doi.org/10.1016/j.nbd.2007.01.005.
60. Domen J, Weissman IL. Self-renewal, differentiation or death: regulation and manipulation of hematopoietic stem cell fate. Mol Med Today 1999; 5:201-8; PMID:10322312; http://dx.doi.org/10.1016/S1357-4310(99)01464-1.
61. Cashman NR, Loertscher R, Nalbantoglu J, Shaw I, Kascsak RJ, Bolton DC, et al. Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell 1990; 61:185-92; PMID:1969332; http://dx.doi.org/10.1016/0092- 8674(90)90225-4.
62. Dodelet VC, Cashman NR. Prion protein expression in human leukocyte differentiation. Blood 1998; 91:1556-61; PMID:9473220.
63. Rovera G, O'Brien TG, Diamond L. Induction of differentiation in human promyelocytic leukemia cells by tumor promoters. Science 1979; 204:868-70; PMID:286421; http://dx.doi.org/10.1126/science.286421.
64. Liu T, Li R, Wong BS, Liu D, Pan T, Petersen RB, et al. Normal cellular prion protein is preferentially expressed on subpopulations of murine hemopoietic cells. J Immunol 2001; 166:3733-42; PMID:11238614.
65. Zhang CC, Steele AD, Lindquist S, Lodish HF. Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal. Proc Natl Acad Sci USA 2006; 103:2184-9; PMID:16467153; http://dx.doi.org/10.1073/pnas.0510577103.
66. Stella R, Massimino ML, Sandri M, Sorgato MC, Bertoli A. Cellular prion protein promotes regeneration of adult muscle tissue. Mol Cell Biol 2010; 30:4864-76; PMID:20679477; http://dx.doi.org/10.1128/MCB.01040-09.
67. Tanaka EM, Reddien PW. The cellular basis for animal regeneration. Dev Cell 2011; 21:172-85; PMID:21763617; http://dx.doi.org/10.1016/j.devcel.2011.06. 016.