-
1
-
-
17944373014
-
Human hypertension caused by mutations in WNK kinases
-
Wilson FH, Disse-Nicodeme S, Choate KA, Ishikawa K, Nelson-Williams C, et al. (2001) Human hypertension caused by mutations in WNK kinases. Science 293: 1107-1112.
-
(2001)
Science
, vol.293
, pp. 1107-1112
-
-
Wilson, F.H.1
Disse-Nicodeme, S.2
Choate, K.A.3
Ishikawa, K.4
Nelson-Williams, C.5
-
3
-
-
78751654853
-
The WNKs: atypical protein kinases with pleiotropic actions
-
McCormick JA, Ellison DH, (2011) The WNKs: atypical protein kinases with pleiotropic actions. Physiol Rev 91: 177-219.
-
(2011)
Physiol Rev
, vol.91
, pp. 177-219
-
-
McCormick, J.A.1
Ellison, D.H.2
-
4
-
-
80051945662
-
WNK1 Regulates Vasoconstriction and Blood Pressure Response to {alpha}1-Adrenergic Stimulation in Mice
-
Bergaya S, Faure S, Baudrie V, Rio M, Escoubet B, et al. (2011) WNK1 Regulates Vasoconstriction and Blood Pressure Response to {alpha}1-Adrenergic Stimulation in Mice. Hypertension.
-
(2011)
Hypertension
-
-
Bergaya, S.1
Faure, S.2
Baudrie, V.3
Rio, M.4
Escoubet, B.5
-
5
-
-
70349238716
-
Endothelial-Specific Expression of WNK1 Kinase Is Essential for Angiogenesis and Heart Development in Mice
-
Xie J, Wu T, Xu K, Huang IK, Cleaver O, et al. (2009) Endothelial-Specific Expression of WNK1 Kinase Is Essential for Angiogenesis and Heart Development in Mice. Am J Pathol.
-
(2009)
Am J Pathol
-
-
Xie, J.1
Wu, T.2
Xu, K.3
Huang, I.K.4
Cleaver, O.5
-
6
-
-
10744226663
-
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention
-
Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, et al. (2003) Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A 100: 14109-14114.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 14109-14114
-
-
Zambrowicz, B.P.1
Abuin, A.2
Ramirez-Solis, R.3
Richter, L.J.4
Piggott, J.5
-
7
-
-
0842309871
-
Genome-wide RNAi analysis of growth and viability in Drosophila cells
-
Boutros M, Kiger AA, Armknecht S, Kerr K, Hild M, et al. (2004) Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303: 832-835.
-
(2004)
Science
, vol.303
, pp. 832-835
-
-
Boutros, M.1
Kiger, A.A.2
Armknecht, S.3
Kerr, K.4
Hild, M.5
-
8
-
-
33750484312
-
Down-regulation of WNK1 protein kinase in neural progenitor cells suppresses cell proliferation and migration
-
Sun X, Gao L, Yu RK, Zeng G, (2006) Down-regulation of WNK1 protein kinase in neural progenitor cells suppresses cell proliferation and migration. J Neurochem 99: 1114-1121.
-
(2006)
J Neurochem
, vol.99
, pp. 1114-1121
-
-
Sun, X.1
Gao, L.2
Yu, R.K.3
Zeng, G.4
-
9
-
-
1542319971
-
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
-
Xu BE, Stippec S, Lenertz L, Lee BH, Zhang W, et al. (2004) WNK1 activates ERK5 by an MEKK2/3-dependent mechanism. J Biol Chem 279: 7826-7831.
-
(2004)
J Biol Chem
, vol.279
, pp. 7826-7831
-
-
Xu, B.E.1
Stippec, S.2
Lenertz, L.3
Lee, B.H.4
Zhang, W.5
-
10
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, et al. (2007) Patterns of somatic mutation in human cancer genomes. Nature 446: 153-158.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
Dalgliesh, G.L.4
Hunter, C.5
-
11
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J, et al. (2006) The consensus coding sequences of human breast and colorectal cancers. Science 314: 268-274.
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
-
12
-
-
20044381123
-
A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer
-
Stephens P, Edkins S, Davies H, Greenman C, Cox C, et al. (2005) A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nat Genet 37: 590-592.
-
(2005)
Nat Genet
, vol.37
, pp. 590-592
-
-
Stephens, P.1
Edkins, S.2
Davies, H.3
Greenman, C.4
Cox, C.5
-
13
-
-
46749127782
-
Mutations in the nervous system-specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II
-
Shekarabi M, Girard N, Riviere JB, Dion P, Houle M, et al. (2008) Mutations in the nervous system-specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II. J Clin Invest 118: 2496-2505.
-
(2008)
J Clin Invest
, vol.118
, pp. 2496-2505
-
-
Shekarabi, M.1
Girard, N.2
Riviere, J.B.3
Dion, P.4
Houle, M.5
-
14
-
-
0344197746
-
Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform
-
Delaloy C, Lu J, Houot AM, Disse-Nicodeme S, Gasc JM, et al. (2003) Multiple promoters in the WNK1 gene: one controls expression of a kidney-specific kinase-defective isoform. Mol Cell Biol 23: 9208-9221.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 9208-9221
-
-
Delaloy, C.1
Lu, J.2
Houot, A.M.3
Disse-Nicodeme, S.4
Gasc, J.M.5
-
15
-
-
0141455346
-
WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain
-
O'Reilly M, Marshall E, Speirs HJ, Brown RW, (2003) WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain. J Am Soc Nephrol 14: 2447-2456.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 2447-2456
-
-
O'Reilly, M.1
Marshall, E.2
Speirs, H.J.3
Brown, R.W.4
-
16
-
-
0035817725
-
WNK kinases, a novel protein kinase subfamily in multi-cellular organisms
-
Verissimo F, Jordan P, (2001) WNK kinases, a novel protein kinase subfamily in multi-cellular organisms. Oncogene 20: 5562-5569.
-
(2001)
Oncogene
, vol.20
, pp. 5562-5569
-
-
Verissimo, F.1
Jordan, P.2
-
17
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
18
-
-
0034595634
-
WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II
-
Xu B, English JM, Wilsbacher JL, Stippec S, Goldsmith EJ, et al. (2000) WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II. J Biol Chem 275: 16795-16801.
-
(2000)
J Biol Chem
, vol.275
, pp. 16795-16801
-
-
Xu, B.1
English, J.M.2
Wilsbacher, J.L.3
Stippec, S.4
Goldsmith, E.J.5
-
19
-
-
0028808016
-
Stimulation of calcium transport by amiloride in mouse distal convoluted tubule cells
-
Friedman PA, Gesek FA, (1995) Stimulation of calcium transport by amiloride in mouse distal convoluted tubule cells. Kidney Int 48: 1427-1434.
-
(1995)
Kidney Int
, vol.48
, pp. 1427-1434
-
-
Friedman, P.A.1
Gesek, F.A.2
-
20
-
-
33748095919
-
Comparison of relative mRNA quantification models and the impact of RNA integrity in quantitative real-time RT-PCR
-
Fleige S, Walf V, Huch S, Prgomet C, Sehm J, et al. (2006) Comparison of relative mRNA quantification models and the impact of RNA integrity in quantitative real-time RT-PCR. Biotechnol Lett 28: 1601-1613.
-
(2006)
Biotechnol Lett
, vol.28
, pp. 1601-1613
-
-
Fleige, S.1
Walf, V.2
Huch, S.3
Prgomet, C.4
Sehm, J.5
-
21
-
-
3142600709
-
Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension
-
Min X, Lee BH, Cobb MH, Goldsmith EJ, (2004) Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension. Structure 12: 1303-1311.
-
(2004)
Structure
, vol.12
, pp. 1303-1311
-
-
Min, X.1
Lee, B.H.2
Cobb, M.H.3
Goldsmith, E.J.4
-
22
-
-
33745700719
-
Cardiovascular expression of the mouse WNK1 gene during development and adulthood revealed by a BAC reporter assay
-
Delaloy C, Hadchouel J, Imbert-Teboul M, Clemessy M, Houot AM, et al. (2006) Cardiovascular expression of the mouse WNK1 gene during development and adulthood revealed by a BAC reporter assay. Am J Pathol 169: 105-118.
-
(2006)
Am J Pathol
, vol.169
, pp. 105-118
-
-
Delaloy, C.1
Hadchouel, J.2
Imbert-Teboul, M.3
Clemessy, M.4
Houot, A.M.5
-
23
-
-
0037457954
-
WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia
-
Choate KA, Kahle KT, Wilson FH, Nelson-Williams C, Lifton RP, (2003) WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl--transporting epithelia. Proc Natl Acad Sci U S A 100: 663-668.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 663-668
-
-
Choate, K.A.1
Kahle, K.T.2
Wilson, F.H.3
Nelson-Williams, C.4
Lifton, R.P.5
-
24
-
-
67449090606
-
Renal and brain isoforms of WNK3 have opposite effects on NCCT expression
-
Glover M, Zuber AM, O'Shaughnessy KM, (2009) Renal and brain isoforms of WNK3 have opposite effects on NCCT expression. J Am Soc Nephrol 20: 1314-1322.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1314-1322
-
-
Glover, M.1
Zuber, A.M.2
O'Shaughnessy, K.M.3
-
25
-
-
80052307525
-
Similar effects of all WNK3 variants on SLC12 cotransporters
-
Cruz-Rangel S, Melo Z, Vazquez N, Meade P, Bobadilla NA, et al. (2011) Similar effects of all WNK3 variants on SLC12 cotransporters. Am J Physiol Cell Physiol 301: C601-608.
-
(2011)
Am J Physiol Cell Physiol
, vol.301
-
-
Cruz-Rangel, S.1
Melo, Z.2
Vazquez, N.3
Meade, P.4
Bobadilla, N.A.5
-
26
-
-
8644269702
-
Heterogeneous distribution of chloride channels along the distal convoluted tubule probed by single-cell RT-PCR and patch clamp
-
Nissant A, Lourdel S, Baillet S, Paulais M, Marvao P, et al. (2004) Heterogeneous distribution of chloride channels along the distal convoluted tubule probed by single-cell RT-PCR and patch clamp. Am J Physiol Renal Physiol 287: F1233-1243.
-
(2004)
Am J Physiol Renal Physiol
, vol.287
-
-
Nissant, A.1
Lourdel, S.2
Baillet, S.3
Paulais, M.4
Marvao, P.5
-
27
-
-
57649115440
-
Proteinase-activated receptor 2 stimulates Na,K-ATPase and sodium reabsorption in native kidney epithelium
-
Morla L, Crambert G, Mordasini D, Favre G, Doucet A, et al. (2008) Proteinase-activated receptor 2 stimulates Na,K-ATPase and sodium reabsorption in native kidney epithelium. J Biol Chem 283: 28020-28028.
-
(2008)
J Biol Chem
, vol.283
, pp. 28020-28028
-
-
Morla, L.1
Crambert, G.2
Mordasini, D.3
Favre, G.4
Doucet, A.5
-
28
-
-
79951929094
-
Atlas of gene expression in the mouse kidney: new features of glomerular parietal cells
-
Cheval L, Pierrat F, Dossat C, Genete M, Imbert-Teboul M, et al. (2011) Atlas of gene expression in the mouse kidney: new features of glomerular parietal cells. Physiol Genomics 43: 161-173.
-
(2011)
Physiol Genomics
, vol.43
, pp. 161-173
-
-
Cheval, L.1
Pierrat, F.2
Dossat, C.3
Genete, M.4
Imbert-Teboul, M.5
-
29
-
-
41949137062
-
Defective ENaC processing and function in tissue kallikrein-deficient mice
-
Picard N, Eladari D, El Moghrabi S, Planes C, Bourgeois S, et al. (2008) Defective ENaC processing and function in tissue kallikrein-deficient mice. J Biol Chem 283: 4602-4611.
-
(2008)
J Biol Chem
, vol.283
, pp. 4602-4611
-
-
Picard, N.1
Eladari, D.2
El Moghrabi, S.3
Planes, C.4
Bourgeois, S.5
|