Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes

Oncogene

Volumn 31, Issue 22, 2012, Pages 2750-2760

  Schepeler, T ^a   Holm, A ^a   Halvey, P ^b   Nordentoft, I ^a   Lamy, P ^a   Riising, E M ^c   Christensen, L L ^a   Thorsen, K ^a   Liebler, D C ^b   Helin, K ^c   Oorntoft T F ^a   Andersen, C L ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Cancer; MicroRNA; MiR 30e 3p; PIK3C2A; TCF4; Wnt

Indexed keywords

BETA CATENIN; MICRORNA; MICRORNA 126; MICRORNA 139 5P; MICRORNA 145; MICRORNA 30E 3P; TRANSCRIPTOME; UNCLASSIFIED DRUG; WNT PROTEIN;

3' UNTRANSLATED REGION; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CANCER GROWTH; CARCINOGENESIS; CELL VIABILITY; CHROMATIN; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION PROFILING; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROARRAY ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEOMICS; SIGNAL TRANSDUCTION;

AGED; AGED, 80 AND OVER; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BETA CATENIN; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, LIQUID; COLON; COLORECTAL NEOPLASMS; FEMALE; GENE EXPRESSION PROFILING; GENES, DOMINANT; HUMANS; LUCIFERASES; MALE; MICRORNAS; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENES; RECTUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSCRIPTION FACTORS; TRANSCRIPTOME; TUMOR CELLS, CULTURED; WNT SIGNALING PATHWAY;

EID: 84861709195     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.453     Document Type: Article

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