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Volumn 56, Issue 5, 2012, Pages 733-740

Squalene ameliorates atherosclerotic lesions through the reduction of CD36 scavenger receptor expression in macrophages

Author keywords

Atherosclerosis; Hydroxytyrosol; Minor compounds; Olive oil; Squalene

Indexed keywords

3,4-DIHYDROXYPHENYLETHANOL; 4-HYDROXYPHENYLETHANOL; ANTIOXIDANT; CD36 ANTIGEN; DRUG DERIVATIVE; HYDROXYTYROSOL; LOW DENSITY LIPOPROTEIN; OLIVE OIL; OXIDIZED LOW DENSITY LIPOPROTEIN; PHENETHYL ALCOHOL; SQUALENE; TYROSOL; VEGETABLE OIL;

EID: 84861691259     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201100703     Document Type: Article
Times cited : (34)

References (41)
  • 1
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis, A. J., Atherosclerosis. Nature 2000, 407, 233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 3
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby, P., Inflammation in atherosclerosis. Nature 2002, 420, 868-874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 4
    • 61749103652 scopus 로고    scopus 로고
    • CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima
    • Park, Y. M., Febbraio, M., Silverstein, R. L., CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima. J. Clin. Invest. 2009, 119, 136-145.
    • (2009) J. Clin. Invest. , vol.119 , pp. 136-145
    • Park, Y.M.1    Febbraio, M.2    Silverstein, R.L.3
  • 5
    • 74849121758 scopus 로고    scopus 로고
    • Dietary compound quercitrin dampens VEGF induction and PPARgamma activation in oxidized LDL-exposed murine macrophages: association with scavenger receptor CD36
    • Choi, J. S., Bae, J. Y., Kim, D. S., Li, J. et al., Dietary compound quercitrin dampens VEGF induction and PPARgamma activation in oxidized LDL-exposed murine macrophages: association with scavenger receptor CD36. J. Agric. Food Chem. 2010, 58, 1333-1341.
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 1333-1341
    • Choi, J.S.1    Bae, J.Y.2    Kim, D.S.3    Li, J.4
  • 6
    • 67649314071 scopus 로고    scopus 로고
    • The role of the scavenger receptor CD36 in regulating mononuclear phagocyte trafficking to atherosclerotic lesions and vascular inflammation
    • Harb, D., Bujold, K., Febbraio, M., Sirois, M. G. et al., The role of the scavenger receptor CD36 in regulating mononuclear phagocyte trafficking to atherosclerotic lesions and vascular inflammation. Cardiovasc. Res. 2009, 83, 42-51.
    • (2009) Cardiovasc. Res. , vol.83 , pp. 42-51
    • Harb, D.1    Bujold, K.2    Febbraio, M.3    Sirois, M.G.4
  • 7
    • 67650905114 scopus 로고    scopus 로고
    • oxLDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation
    • Nickel, T., Schmauss, D., Hanssen, H., Sicic, Z. et al., oxLDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation. Atherosclerosis 2009, 205, 442-450.
    • (2009) Atherosclerosis , vol.205 , pp. 442-450
    • Nickel, T.1    Schmauss, D.2    Hanssen, H.3    Sicic, Z.4
  • 8
    • 64549154448 scopus 로고    scopus 로고
    • Inhibitory effects of grape seed procyanidins on foam cell formation in vitro
    • Terra, X., Fernández-Larrea, J., Pujadas, G., Ardèvol, A. et al., Inhibitory effects of grape seed procyanidins on foam cell formation in vitro. J. Agric. Food Chem. 2009, 57, 2588-2594.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 2588-2594
    • Terra, X.1    Fernández-Larrea, J.2    Pujadas, G.3    Ardèvol, A.4
  • 9
    • 73849107792 scopus 로고    scopus 로고
    • Nobiletin metabolite, 3',4'-dihydroxy-5,6,7,8-tetramethoxyflavone, inhibits LDL oxidation and down-regulates scavenger receptor expression and activity in THP-1 cells
    • Lo, Y. H., Pan, M. H., Li, S., Yen, J. H. et al., Nobiletin metabolite, 3', 4'-dihydroxy-5, 6, 7, 8-tetramethoxyflavone, inhibits LDL oxidation and down-regulates scavenger receptor expression and activity in THP-1 cells. Biochim. Biophys. Acta. 2010, 1801, 114-126.
    • (2010) Biochim. Biophys. Acta. , vol.1801 , pp. 114-126
    • Lo, Y.H.1    Pan, M.H.2    Li, S.3    Yen, J.H.4
  • 10
    • 77950952757 scopus 로고    scopus 로고
    • Olive oil and health: summary of the II international conference on olive oil and health consensus report, Jaén and Córdoba (Spain) 2008
    • López-Miranda, J., Pérez-Jiménez, F., Ros, E., De Caterina, R. et al., Olive oil and health: summary of the II international conference on olive oil and health consensus report, Jaén and Córdoba (Spain) 2008. Nutr. Metab. Cardiovasc. Dis. 2010, 20, 284-294.
    • (2010) Nutr. Metab. Cardiovasc. Dis. , vol.20 , pp. 284-294
    • López-Miranda, J.1    Pérez-Jiménez, F.2    Ros, E.3    De Caterina, R.4
  • 12
    • 0036233708 scopus 로고    scopus 로고
    • Sunflower, virgin-olive and fish oils differentially affect the progression of aortic lesions in rabbits with experimental atherosclerosis
    • Aguilera, C. M., Ramírez-Tortosa, M. C., Mesa, M. D., Ramírez-Tortosa, C. L., et al., Sunflower, virgin-olive and fish oils differentially affect the progression of aortic lesions in rabbits with experimental atherosclerosis. Atherosclerosis 2002, 162, 335-344.
    • (2002) Atherosclerosis , vol.162 , pp. 335-344
    • Aguilera, C.M.1    Ramírez-Tortosa, M.C.2    Mesa, M.D.3    Ramírez-Tortosa, C.L.4
  • 13
    • 34248221610 scopus 로고    scopus 로고
    • Olive oil preparation determines the atherosclerotic protection in apolipoprotein E knockout mice
    • Acín, S., Navarro, M. A., Perona, J. S., Arbonés-Mainar, J. M. et al., Olive oil preparation determines the atherosclerotic protection in apolipoprotein E knockout mice. J. Nutr. Biochem. 2007, 18, 418-424.
    • (2007) J. Nutr. Biochem. , vol.18 , pp. 418-424
    • Acín, S.1    Navarro, M.A.2    Perona, J.S.3    Arbonés-Mainar, J.M.4
  • 14
    • 79960697415 scopus 로고    scopus 로고
    • The effect of olive oil polyphenols on antibodies against oxidized LDL. A randomized clinical trial
    • EUROLIVE Study Group
    • Castañer, O., Fitó, M., López-Sabater, M. C., Poulsen, H. E. EUROLIVE Study Group et al., The effect of olive oil polyphenols on antibodies against oxidized LDL. A randomized clinical trial. Clin. Nutr. 2011, 30, 490-493.
    • (2011) Clin. Nutr. , vol.30 , pp. 490-493
    • Castañer, O.1    Fitó, M.2    López-Sabater, M.C.3    Poulsen, H.E.4
  • 15
    • 0035076365 scopus 로고    scopus 로고
    • An olive oil-rich diet reduces scavenger receptor mRNA in murine macrophages
    • Miles, E. A., Wallace, F. A., Calder, P. C., An olive oil-rich diet reduces scavenger receptor mRNA in murine macrophages. Br. J. Nutr. 2001, 85, 185-191.
    • (2001) Br. J. Nutr. , vol.85 , pp. 185-191
    • Miles, E.A.1    Wallace, F.A.2    Calder, P.C.3
  • 16
    • 33750201671 scopus 로고    scopus 로고
    • Minor components of olive oil: evidence to date of health benefits in humans
    • Covas, M. I., Ruiz-Gutiérrez, V., Torre, R., Kafatos, A. et al., Minor components of olive oil: evidence to date of health benefits in humans. Nutr. Rev. 2006, 64, 220-230.
    • (2006) Nutr. Rev. , vol.64 , pp. 220-230
    • Covas, M.I.1    Ruiz-Gutiérrez, V.2    Torre, R.3    Kafatos, A.4
  • 17
    • 0032902899 scopus 로고    scopus 로고
    • Solid monounsaturated diet lowers LDL unsaturation trait and oxidisability in hypercholesterolemic (type IIb) patients
    • Baroni, S. S., Amelio, M., Sangiorgi, Z., Gaddi, A., et al., Solid monounsaturated diet lowers LDL unsaturation trait and oxidisability in hypercholesterolemic (type IIb) patients. Free Radic. Res. 1999, 30, 275-285.
    • (1999) Free Radic. Res. , vol.30 , pp. 275-285
    • Baroni, S.S.1    Amelio, M.2    Sangiorgi, Z.3    Gaddi, A.4
  • 19
    • 0032700863 scopus 로고    scopus 로고
    • Extra-virgin olive oil increases the resistance of LDL to oxidation more than refined olive oil in free-living men with peripheral vascular disease
    • Ramirez-Tortosa, M. C., Urbano, G., López-Jurado, M., Nestares, T. et al., Extra-virgin olive oil increases the resistance of LDL to oxidation more than refined olive oil in free-living men with peripheral vascular disease. J. Nutr. 1999, 129, 2177-2183.
    • (1999) J. Nutr. , vol.129 , pp. 2177-2183
    • Ramirez-Tortosa, M.C.1    Urbano, G.2    López-Jurado, M.3    Nestares, T.4
  • 20
    • 67949091005 scopus 로고    scopus 로고
    • Gingival vascular damage in atherosclerotic rabbits: hydroxytyrosol and squalene benefits
    • Bullon, P., Quiles, J. L., Morillo, J. M., Rubini, C. et al., Gingival vascular damage in atherosclerotic rabbits: hydroxytyrosol and squalene benefits. Food Chem. Toxicol. 2009, 47, 2327-2331.
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 2327-2331
    • Bullon, P.1    Quiles, J.L.2    Morillo, J.M.3    Rubini, C.4
  • 21
    • 84861689171 scopus 로고    scopus 로고
    • Expression of proinflammatory, proatherogenic genes is reduced by the Mediterranean diet in elderly people
    • Camargo, A., Delgado-Lista, J., Garcia-Rios, A., Cruz-Teno, C. et al., Expression of proinflammatory, proatherogenic genes is reduced by the Mediterranean diet in elderly people. Br. J. Nutr. 2011, 15, 1-9.
    • (2011) Br. J. Nutr. , vol.15 , pp. 1-9
    • Camargo, A.1    Delgado-Lista, J.2    Garcia-Rios, A.3    Cruz-Teno, C.4
  • 22
    • 26844480960 scopus 로고    scopus 로고
    • Interaction of SP-A (surfactant protein A) with bacterial rough lipopolysaccharide (Re-LPS), and effects of SP-A on the binding of Re-LPS to CD14 and LPS-binding protein
    • García-Verdugo, I., Sánchez-Barbero, F., Soldau, K., Tobias, P. S., et al., Interaction of SP-A (surfactant protein A) with bacterial rough lipopolysaccharide (Re-LPS), and effects of SP-A on the binding of Re-LPS to CD14 and LPS-binding protein. Biochem. J. 2005, 391, 115-124.
    • (2005) Biochem. J. , vol.391 , pp. 115-124
    • García-Verdugo, I.1    Sánchez-Barbero, F.2    Soldau, K.3    Tobias, P.S.4
  • 23
    • 0031046475 scopus 로고    scopus 로고
    • Inhibitors of arterial relaxation among components of human oxidized low-density lipoproteins. Cholesterol derivatives oxidized in position 7 are potent inhibitors of endothelium-dependent relaxation
    • Deckert, V., Perségol, L., Viens, L., Lizard, G. et al., Inhibitors of arterial relaxation among components of human oxidized low-density lipoproteins. Cholesterol derivatives oxidized in position 7 are potent inhibitors of endothelium-dependent relaxation. Circulation 1997, 95, 723-731.
    • (1997) Circulation , vol.95 , pp. 723-731
    • Deckert, V.1    Perségol, L.2    Viens, L.3    Lizard, G.4
  • 24
    • 0036840613 scopus 로고    scopus 로고
    • Prevention of LDL alpha-tocopherol consumption, cholesterol oxidation, and vascular endothelium dysfunction by polyphenolic compounds from red wine
    • Deckert, V., Desrumaux, C., Athias, A., Duverneuil, L. et al., Prevention of LDL alpha-tocopherol consumption, cholesterol oxidation, and vascular endothelium dysfunction by polyphenolic compounds from red wine. Atherosclerosis 2002, 165, 41-50.
    • (2002) Atherosclerosis , vol.165 , pp. 41-50
    • Deckert, V.1    Desrumaux, C.2    Athias, A.3    Duverneuil, L.4
  • 25
    • 3242730602 scopus 로고    scopus 로고
    • Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on the oxidizability and thrombogenicity of low-density lipoprotein
    • Mesa, M. D., Buckley, R., Minihane, A. M., Yaqoob, P., Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on the oxidizability and thrombogenicity of low-density lipoprotein. Atherosclerosis 2004, 175, 333-343.
    • (2004) Atherosclerosis , vol.175 , pp. 333-343
    • Mesa, M.D.1    Buckley, R.2    Minihane, A.M.3    Yaqoob, P.4
  • 26
    • 0024550456 scopus 로고
    • Continuous monitoring of in vitro oxidation of human low density lipoprotein
    • Esterbauer, H., Striegl, G., Puhl, H., Rotheneder, M., Continuous monitoring of in vitro oxidation of human low density lipoprotein. Free Radic. Res. Commun. 1989, 6, 67-75.
    • (1989) Free Radic. Res. Commun. , vol.6 , pp. 67-75
    • Esterbauer, H.1    Striegl, G.2    Puhl, H.3    Rotheneder, M.4
  • 27
    • 0023019005 scopus 로고
    • Use of MTT colorimetric assay to measure cell activation
    • Gerlier, D., Homasset, N., Use of MTT colorimetric assay to measure cell activation. J. Immunol. Methods. 1986, 94, 57-63.
    • (1986) J. Immunol. Methods. , vol.94 , pp. 57-63
    • Gerlier, D.1    Homasset, N.2
  • 28
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V
    • Vermes, I., Haanen, C., Steffens, N. H., Reutelingsperger, C., A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J. Immunol. Methods. 1995, 184, 39-51.
    • (1995) J. Immunol. Methods. , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens, N.H.3    Reutelingsperger, C.4
  • 29
    • 75049085882 scopus 로고    scopus 로고
    • Effect of Mediterranean diet on the expression of pro-atherogenic genes in a population at high cardiovascular risk
    • Llorente-Cortés, V., Estruch, R., Mena, M. P., Ros, E. et al., Effect of Mediterranean diet on the expression of pro-atherogenic genes in a population at high cardiovascular risk. Atherosclerosis 2010, 208, 442-450.
    • (2010) Atherosclerosis , vol.208 , pp. 442-450
    • Llorente-Cortés, V.1    Estruch, R.2    Mena, M.P.3    Ros, E.4
  • 30
    • 39449090109 scopus 로고    scopus 로고
    • Squalene in a sex-dependent manner modulates atherosclerotic lesion which correlates with hepatic fat content in apoE-knockout male mice
    • Guillén, N., Acín, S., Navarro, M. A., Perona, J. S. et al., Squalene in a sex-dependent manner modulates atherosclerotic lesion which correlates with hepatic fat content in apoE-knockout male mice. Atherosclerosis 2008, 197, 72-83.
    • (2008) Atherosclerosis , vol.197 , pp. 72-83
    • Guillén, N.1    Acín, S.2    Navarro, M.A.3    Perona, J.S.4
  • 31
    • 0024496727 scopus 로고
    • Variations of hepatic cholesterol precursors during altered flows of endogenous and exogenous squalene in the rat
    • Strandberg, T. E., Tilvis, R. S., Miettinen, T. A., Variations of hepatic cholesterol precursors during altered flows of endogenous and exogenous squalene in the rat. Biochim. Biophys. Acta 1989, 1001, 150-156.
    • (1989) Biochim. Biophys. Acta , vol.1001 , pp. 150-156
    • Strandberg, T.E.1    Tilvis, R.S.2    Miettinen, T.A.3
  • 32
    • 1242336795 scopus 로고    scopus 로고
    • Pitavastatin downregulates expression of the macrophage type B scavenger receptor, CD36
    • Han, J., Zhou, X., Yokoyama, T., Hajjar, D. P. et al., Pitavastatin downregulates expression of the macrophage type B scavenger receptor, CD36. Circulation 2004, 109, 790-796.
    • (2004) Circulation , vol.109 , pp. 790-796
    • Han, J.1    Zhou, X.2    Yokoyama, T.3    Hajjar, D.P.4
  • 33
    • 34447563762 scopus 로고    scopus 로고
    • Anti-adipogenic action of pitavastatin occurs through the coordinate regulation of PPARgamma and Pref-1 expression
    • Nicholson, A. C., Hajjar, D. P., Zhou, X., He, W. et al., Anti-adipogenic action of pitavastatin occurs through the coordinate regulation of PPARgamma and Pref-1 expression. Br. J. Pharmacol. 2007, 151, 807-815.
    • (2007) Br. J. Pharmacol. , vol.151 , pp. 807-815
    • Nicholson, A.C.1    Hajjar, D.P.2    Zhou, X.3    He, W.4
  • 34
    • 0032540012 scopus 로고    scopus 로고
    • PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz, P., Nagy, L., Alvarez, J. G., Thomazy, V. A., et al., PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998, 93, 241-252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4
  • 35
    • 34249048898 scopus 로고    scopus 로고
    • Lycopene, quercetin and tyrosol prevent macrophage activation induced by gliadin and IFN-gamma
    • De Stefano, D., Maiuri, M. C., Simeon, V., Grassia, G. et al., Lycopene, quercetin and tyrosol prevent macrophage activation induced by gliadin and IFN-gamma. Eur. J. Pharmacol. 2007, 566, 192-199.
    • (2007) Eur. J. Pharmacol. , vol.566 , pp. 192-199
    • De Stefano, D.1    Maiuri, M.C.2    Simeon, V.3    Grassia, G.4
  • 36
    • 33746567447 scopus 로고    scopus 로고
    • One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development
    • González-Santiago, M., Martín-Bautista, E., Carrero, J. J., Fonollá, J. et al., One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development. Atherosclerosis 2006, 188, 35-42.
    • (2006) Atherosclerosis , vol.188 , pp. 35-42
    • González-Santiago, M.1    Martín-Bautista, E.2    Carrero, J.J.3    Fonollá, J.4
  • 37
    • 33750727360 scopus 로고    scopus 로고
    • Hydroxytyrosol administration enhances atherosclerotic lesion development in apo E deficient mice
    • Acín, S., Navarro, M. A., Arbonés-Mainar, J. M., Guillén, N. et al., Hydroxytyrosol administration enhances atherosclerotic lesion development in apo E deficient mice. J. Biochem. 2006, 140, 383-391.
    • (2006) J. Biochem. , vol.140 , pp. 383-391
    • Acín, S.1    Navarro, M.A.2    Arbonés-Mainar, J.M.3    Guillén, N.4
  • 38
    • 0034735996 scopus 로고    scopus 로고
    • Hydroxytyrosol, a natural molecule occurring in olive oil, induces cytochrome C-dependent apoptosis
    • Ragione, F. D., Cucciolla, V., Borriello, A., Pietra, V. D. et al., Hydroxytyrosol, a natural molecule occurring in olive oil, induces cytochrome C-dependent apoptosis. Biochem. Biophys. Res. Commun. 2000, 278, 733-739.
    • (2000) Biochem. Biophys. Res. Commun. , vol.278 , pp. 733-739
    • Ragione, F.D.1    Cucciolla, V.2    Borriello, A.3    Pietra, V.D.4
  • 39
    • 38049095656 scopus 로고    scopus 로고
    • Cytoprotective effects of phenolic antioxidants and essential fatty acids in human blood monocyte and neuroblastoma cell lines: surrogates for neurological damage in vivo
    • Young, J., Wahle, K. W., Boyle, S. P., Cytoprotective effects of phenolic antioxidants and essential fatty acids in human blood monocyte and neuroblastoma cell lines: surrogates for neurological damage in vivo. Prostaglandins Leukot. Essent. Fatty Acids 2008, 78, 45-59.
    • (2008) Prostaglandins Leukot. Essent. Fatty Acids , vol.78 , pp. 45-59
    • Young, J.1    Wahle, K.W.2    Boyle, S.P.3
  • 40
    • 64749111428 scopus 로고    scopus 로고
    • Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells
    • Zhang, X., Cao, J., Zhong, L., Hydroxytyrosol inhibits pro-inflammatory cytokines, iNOS, and COX-2 expression in human monocytic cells. Naunyn Schmiedebergs Arch. Pharmacol. 2009, 379, 581-586.
    • (2009) Naunyn Schmiedebergs Arch. Pharmacol. , vol.379 , pp. 581-586
    • Zhang, X.1    Cao, J.2    Zhong, L.3
  • 41
    • 34547468916 scopus 로고    scopus 로고
    • Tyrosol, the major extra virgin olive oil compound, restored intracellular antioxidant defences in spite of its weak antioxidative effectiveness
    • Di Benedetto, R., Varì, R., Scazzocchio, B., Filesi, C. et al., Tyrosol, the major extra virgin olive oil compound, restored intracellular antioxidant defences in spite of its weak antioxidative effectiveness. Nutr. Metab. Cardiovasc. Dis. 2007, 17, 535-545.
    • (2007) Nutr. Metab. Cardiovasc. Dis. , vol.17 , pp. 535-545
    • Di Benedetto, R.1    Varì, R.2    Scazzocchio, B.3    Filesi, C.4


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