Identification of curcumin targets in neuroinflammatory pathways: Molecular docking scores with GSK-3β, P38 MAPK, COX, ICE and TACE enzymes

Acta Poloniae Pharmaceutica - Drug Research

Volumn 69, Issue 2, 2012, Pages 237-245

  Elumalai, Manogaran ^a   Muthaiah, Ramanathan ^a   Ali, Mohamed Ashraf ^b  

^a PSG COLLEGE OF PHARMACY   (India)

^b SCHOOL OF PHYSICS   (Malaysia)

Author keywords

COX; Curcumin; Glycogen synthase kinase (GSK 3 ); Interleukin 1 converting enzyme (ICE); p38 mitogen activated protein kinase (MAPK); Tumor necrosis factor converting enzyme (TACE)

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CURCUMIN; GLYCINE; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROGEN; INTERLEUKIN 1BETA CONVERTING ENZYME; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN SYNTHASE; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; VALINE; ADAM PROTEIN; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG CONFORMATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; ENZYME SUBSTRATE; HYDROGEN BOND; MOLECULAR DOCKING; NERVOUS SYSTEM INFLAMMATION; CHEMISTRY; PROTEIN CONFORMATION;

ADAM PROTEINS; ANTI-INFLAMMATORY AGENTS; CASPASE 1; CURCUMIN; CYCLOOXYGENASE 2; GLYCOGEN SYNTHASE KINASE 3; HYDROGEN BONDING; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN CONFORMATION;

EID: 84861674607     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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